TopFIND 4.0

Q6KB66: Keratin, type II cytoskeletal 80

General Information

Protein names
- Keratin, type II cytoskeletal 80
- Cytokeratin-80
- CK-80
- Keratin-80
- K80
- Type-II keratin Kb20
Gene names KRT80
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6KB66

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MACRSCVVGF SSLSSCEVTP VGSPRPGTSG WDSCRAPGPG FSSRSLTGCW SAGTISKVTV 
        70         80         90        100        110        120 
NPGLLVPLDV KLDPAVQQLK NQEKEEMKAL NDKFASLIGK VQALEQRNQL LETRWSFLQG 
       130        140        150        160        170        180 
QDSAIFDLGH LYEEYQGRLQ EELRKVSQER GQLEANLLQV LEKVEEFRIR YEDEISKRTD 
       190        200        210        220        230        240 
MEFTFVQLKK DLDAECLHRT ELETKLKSLE SFVELMKTIY EQELKDLAAQ VKDVSVTVGM 
       250        260        270        280        290        300 
DSRCHIDLSG IVEEVKAQYD AVAARSLEEA EAYSRSQLEE QAARSAEYGS SLQSSRSEIA 
       310        320        330        340        350        360 
DLNVRIQKLR SQILSVKSHC LKLEENIKTA EEQGELAFQD AKTKLAQLEA ALQQAKQDMA 
       370        380        390        400        410        420 
RQLRKYQELM NVKLALDIEI ATYRKLVEGE EGRMDSPSAT VVSAVQSRCK TAASRSGLSK 
       430        440        450    
APSRKKKGSK GPVIKITEMS EKYFSQESEV SE

Isoforms

- Isoform 2 of Keratin, type II cytoskeletal 80 - Isoform 3 of Keratin, type II cytoskeletal 80

Sequence View

        10         20         30         40         50         60 
MACRSCVVGF SSLSSCEVTP VGSPRPGTSG WDSCRAPGPG FSSRSLTGCW SAGTISKVTV 
        70         80         90        100        110        120 
NPGLLVPLDV KLDPAVQQLK NQEKEEMKAL NDKFASLIGK VQALEQRNQL LETRWSFLQG 
       130        140        150        160        170        180 
QDSAIFDLGH LYEEYQGRLQ EELRKVSQER GQLEANLLQV LEKVEEFRIR YEDEISKRTD 
       190        200        210        220        230        240 
MEFTFVQLKK DLDAECLHRT ELETKLKSLE SFVELMKTIY EQELKDLAAQ VKDVSVTVGM 
       250        260        270        280        290        300 
DSRCHIDLSG IVEEVKAQYD AVAARSLEEA EAYSRSQLEE QAARSAEYGS SLQSSRSEIA 
       310        320        330        340        350        360 
DLNVRIQKLR SQILSVKSHC LKLEENIKTA EEQGELAFQD AKTKLAQLEA ALQQAKQDMA 
       370        380        390        400        410        420 
RQLRKYQELM NVKLALDIEI ATYRKLVEGE EGRMDSPSAT VVSAVQSRCK TAASRSGLSK 
       430        440        450    
APSRKKKGSK GPVIKITEMS EKYFSQESEV SE         10         20         30         40         50         60 
MACRSCVVGF SSLSSCEVTP VGSPRPGTSG WDSCRAPGPG FSSRSLTGCW SAGTISKVTV 
        70         80         90        100        110        120 
NPGLLVPLDV KLDPAVQQLK NQEKEEMKAL NDKFASLIGK VQALEQRNQL LETRWSFLQG 
       130        140        150        160        170        180 
QDSAIFDLGH LYEEYQGRLQ EELRKVSQER GQLEANLLQV LEKVEEFRIR YEDEISKRTD 
       190        200        210        220        230        240 
MEFTFVQLKK DLDAECLHRT ELETKLKSLE SFVELMKTIY EQELKDLAAQ VKDVSVTVGM 
       250        260        270        280        290        300 
DSRCHIDLSG IVEEVKAQYD AVAARSLEEA EAYSRSQLEE QAARSAEYGS SLQSSRSEIA 
       310        320        330        340        350        360 
DLNVRIQKLR SQILSVKSHC LKLEENIKTA EEQGELAFQD AKTKLAQLEA ALQQAKQDMA 
       370        380        390        400        410        420 
RQLRKYQELM NVKLALDIEI ATYRKLVEGE EGRMDSPSAT VVSAVQSRCK TAASRSGLSK 
       430        440        450    
APSRKKKGSK GPVIKITEMS EKYFSQESEV SE



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6KB66-1-unknown MACRSC... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6KB66-1-unknown MACRSC... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78481

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SEVSE 452 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SEVSE 452 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74100

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)