Q6NSJ5: Volume-regulated anion channel subunit LRRC8E

General Information

Protein names	- Volume-regulated anion channel subunit LRRC8E - Leucine-rich repeat-containing protein 8E
Gene names	LRRC8E
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6NSJ5

2 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MIPVAEFKQF TEQQPAFKVL KPWWDVLAEY LTVAMLMIGV FGCTLQVTQD KIICLPNHEL
        70         80         90        100        110        120
QENLSEAPCQ QLLPRGIPEQ IGALQEVKGL KNNLDLQQYS FINQLCYETA LHWYAKYFPY
       130        140        150        160        170        180
LVVIHTLIFM VCTSFWFKFP GTSSKIEHFI SILGKCFDSP WTTRALSEVS GENQKGPAAT
       190        200        210        220        230        240
ERAAATIVAM AGTGPGKAGE GEKEKVLAEP EKVVTEPPVV TLLDKKEGEQ AKALFEKVKK
       250        260        270        280        290        300
FRMHVEEGDI LYTMYIRQTV LKVCKFLAIL VYNLVYVEKI SFLVACRVET SEVTGYASFC
       310        320        330        340        350        360
CNHTKAHLFS KLAFCYISFV CIYGLTCIYT LYWLFHRPLK EYSFRSVREE TGMGDIPDVK
       370        380        390        400        410        420
NDFAFMLHLI DQYDSLYSKR FAVFLSEVSE SRLKQLNLNH EWTPEKLRQK LQRNAAGRLE
       430        440        450        460        470        480
LALCMLPGLP DTVFELSEVE SLRLEAICDI TFPPGLSQLV HLQELSLLHS PARLPFSLQV
       490        500        510        520        530        540
FLRDHLKVMR VKCEELREVP LWVFGLRGLE ELHLEGLFPQ ELARAATLES LRELKQLKVL
       550        560        570        580        590        600
SLRSNAGKVP ASVTDVAGHL QRLSLHNDGA RLVALNSLKK LAALRELELV ACGLERIPHA
       610        620        630        640        650        660
VFSLGALQEL DLKDNHLRSI EEILSFQHCR KLVTLRLWHN QIAYVPEHVR KLRSLEQLYL
       670        680        690        700        710        720
SYNKLETLPS QLGLCSGLRL LDVSHNGLHS LPPEVGLLQN LQHLALSYNA LEALPEELFF
       730        740        750        760        770        780
CRKLRTLLLG DNQLSQLSPH VGALRALSRL ELKGNRLEAL PEELGNCGGL KKAGLLVEDT
       790
LYQGLPAEVR DKMEEE

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6NSJ5-1-unknown	MIPVAE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6NSJ5-130-unknown	MVCTSF...	130		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000473127

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KNNLDL	95	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472642
...TSFWFK	137	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472491
...AAATIV	187	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470302
...AGEGEK	202	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473127
...KMEEE	796	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)