TopFIND 4.0

Q6P087: Mitochondrial mRNA pseudouridine synthase RPUSD3

General Information

Protein names
- Mitochondrial mRNA pseudouridine synthase RPUSD3
- 5.4.99.- {ECO:0000269|PubMed:27974379}
- RNA pseudouridylate synthase domain-containing protein 3
Gene names RPUSD3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6P087

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRAVLAREMD GRRVLGRFWS GWRRGLGVRP VPEDAGFGTE ARHQRQPRGS CQRSGPLGDQ 
        70         80         90        100        110        120 
PFAGLLPKNL SREELVDALR AAVVDRKGPL VTLNKPQGLP VTGKPGELTL FSVLPELSQS 
       130        140        150        160        170        180 
LGLREQELQV VRASGKESSG LVLLSSCPQT ASRLQKYFTH ARRAQRPTAT YCAVTDGIPA 
       190        200        210        220        230        240 
ASEGKIQAAL KLEHIDGVNL TVPVKAPSRK DILEGVKKTL SHFRVVATGS GCALVQLQPL 
       250        260        270        280        290        300 
TVFSSQLQVH MVLQLCPVLG DHMYSARVGT VLGQRFLLPA ENNKPQRQVL DEALLRRLHL 
       310        320        330        340        350    
TPSQAAQLPL HLHLHRLLLP GTRARDTPVE LLAPLPPYFS RTLQCLGLRL Q

Isoforms

- Isoform 2 of RNA pseudouridylate synthase domain-containing protein 3 - Isoform 3 of RNA pseudouridylate synthase domain-containing protein 3 - Isoform 2 of Mitochondrial mRNA pseudouridine synthase RPUSD3 - Isoform 3 of Mitochondrial mRNA pseudouridine synthase RPUSD3

Sequence View

        10         20         30         40         50         60 
MRAVLAREMD GRRVLGRFWS GWRRGLGVRP VPEDAGFGTE ARHQRQPRGS CQRSGPLGDQ 
        70         80         90        100        110        120 
PFAGLLPKNL SREELVDALR AAVVDRKGPL VTLNKPQGLP VTGKPGELTL FSVLPELSQS 
       130        140        150        160        170        180 
LGLREQELQV VRASGKESSG LVLLSSCPQT ASRLQKYFTH ARRAQRPTAT YCAVTDGIPA 
       190        200        210        220        230        240 
ASEGKIQAAL KLEHIDGVNL TVPVKAPSRK DILEGVKKTL SHFRVVATGS GCALVQLQPL 
       250        260        270        280        290        300 
TVFSSQLQVH MVLQLCPVLG DHMYSARVGT VLGQRFLLPA ENNKPQRQVL DEALLRRLHL 
       310        320        330        340        350    
TPSQAAQLPL HLHLHRLLLP GTRARDTPVE LLAPLPPYFS RTLQCLGLRL Q         10         20         30         40         50         60 
MRAVLAREMD GRRVLGRFWS GWRRGLGVRP VPEDAGFGTE ARHQRQPRGS CQRSGPLGDQ 
        70         80         90        100        110        120 
PFAGLLPKNL SREELVDALR AAVVDRKGPL VTLNKPQGLP VTGKPGELTL FSVLPELSQS 
       130        140        150        160        170        180 
LGLREQELQV VRASGKESSG LVLLSSCPQT ASRLQKYFTH ARRAQRPTAT YCAVTDGIPA 
       190        200        210        220        230        240 
ASEGKIQAAL KLEHIDGVNL TVPVKAPSRK DILEGVKKTL SHFRVVATGS GCALVQLQPL 
       250        260        270        280        290        300 
TVFSSQLQVH MVLQLCPVLG DHMYSARVGT VLGQRFLLPA ENNKPQRQVL DEALLRRLHL 
       310        320        330        340        350    
TPSQAAQLPL HLHLHRLLLP GTRARDTPVE LLAPLPPYFS RTLQCLGLRL Q         10         20         30         40         50         60 
MRAVLAREMD GRRVLGRFWS GWRRGLGVRP VPEDAGFGTE ARHQRQPRGS CQRSGPLGDQ 
        70         80         90        100        110        120 
PFAGLLPKNL SREELVDALR AAVVDRKGPL VTLNKPQGLP VTGKPGELTL FSVLPELSQS 
       130        140        150        160        170        180 
LGLREQELQV VRASGKESSG LVLLSSCPQT ASRLQKYFTH ARRAQRPTAT YCAVTDGIPA 
       190        200        210        220        230        240 
ASEGKIQAAL KLEHIDGVNL TVPVKAPSRK DILEGVKKTL SHFRVVATGS GCALVQLQPL 
       250        260        270        280        290        300 
TVFSSQLQVH MVLQLCPVLG DHMYSARVGT VLGQRFLLPA ENNKPQRQVL DEALLRRLHL 
       310        320        330        340        350    
TPSQAAQLPL HLHLHRLLLP GTRARDTPVE LLAPLPPYFS RTLQCLGLRL Q         10         20         30         40         50         60 
MRAVLAREMD GRRVLGRFWS GWRRGLGVRP VPEDAGFGTE ARHQRQPRGS CQRSGPLGDQ 
        70         80         90        100        110        120 
PFAGLLPKNL SREELVDALR AAVVDRKGPL VTLNKPQGLP VTGKPGELTL FSVLPELSQS 
       130        140        150        160        170        180 
LGLREQELQV VRASGKESSG LVLLSSCPQT ASRLQKYFTH ARRAQRPTAT YCAVTDGIPA 
       190        200        210        220        230        240 
ASEGKIQAAL KLEHIDGVNL TVPVKAPSRK DILEGVKKTL SHFRVVATGS GCALVQLQPL 
       250        260        270        280        290        300 
TVFSSQLQVH MVLQLCPVLG DHMYSARVGT VLGQRFLLPA ENNKPQRQVL DEALLRRLHL 
       310        320        330        340        350    
TPSQAAQLPL HLHLHRLLLP GTRARDTPVE LLAPLPPYFS RTLQCLGLRL Q



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6P087-1-unknown MRAVLA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6P087-1-unknown MRAVLA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88438
    Q6P087-1-unknown MRAVLA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88439

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)