Q6P1B1: Xaa-Pro aminopeptidase 1

General Information

Protein names	- Xaa-Pro aminopeptidase 1 - 3.4.11.9 - Aminoacylproline aminopeptidase - Cytosolic aminopeptidase P - Soluble aminopeptidase P - sAmp - X-Pro aminopeptidase 1 - X-prolyl aminopeptidase 1, soluble
Gene names	Xpnpep1
Organism	Mus musculus
Protease Family
Protease ID	M24.009
Chromosome location
UniProt ID	Q6P1B1

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPKVTSELL RQLRQAMRNS EYVAEPIQAY IIPSGDAHQS EYIAPCDCRR AFVSGFDGSA
        70         80         90        100        110        120
GTAIITEEHA AMWTDGRYFL QAAKQMDNNW TLMKMGLKDT PTQEDWLVSV LPEGSRVGVD
       130        140        150        160        170        180
PLIIPTDYWK KMAKVLRSAG HHLVPVKENL VDKIWTDRPE RPCKPLLTLG LDYTGISWKE
       190        200        210        220        230        240
KVADLRLKMA ERSIAWFVVT ALDEIAWLFN LRGSDVEHNP VFFSYAIVGL ETIMLFIDGD
       250        260        270        280        290        300
RVDAPGVKQH LLLDLGLEAE YRIQVLPYKS ILSELKALCA DLSPREKVWV SDKASYAVSE
       310        320        330        340        350        360
AIPKDHRCCM PYTPICIAKA VKNSAESDGM RRAHIKDAVA LCELFNWLEQ EVPKGGVTEI
       370        380        390        400        410        420
SAADKAEEFR RQQADFVDLS FPTISSTGPN GAIIHYAPVP ETNRTLSLDE VYLIDSGAQY
       430        440        450        460        470        480
KDGTTDVTRT MHFGTPTAYE KECFTYVLKG HIAVSAAVFP TGTKGHLLDS FARSALWDSG
       490        500        510        520        530        540
LDYLHGTGHG VGSFLNVHEG PCGISYKTFS DEPLEAGMIV TDEPGYYEDG AFGIRIENVV
       550        560        570        580        590        600
LVVPAKTKYN FNNRGSLTFE PLTLVPIQTK MIDVNALTDK ECDWLNSYHQ TCRDVVGKEL
       610        620
QSQGRQEALE WLIRETEPVS RQH

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6P1B1-2-unmodified	APKVTS...	2		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q6P1B1-2-unknown	APKVTS...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6P1B1-2-unknown	APKVTS...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q6P1B1-413-unknown	LIDSGA...	413	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30615

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SRVGVD	119	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138473
...LDEVYL	412	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30615
...VSRQH	623	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	412	EVYL.\|.LIDS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> XPP1_MOUSE @412

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)