TopFIND 4.0

Q6P1E7: DNA-directed primase/polymerase protein

General Information

Protein names
- DNA-directed primase/polymerase protein
- 2.7.7.-
- Coiled-coil domain-containing protein 111
Gene names Primpol
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q6P1E7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLRKWEARVK QIEERASHYE RKPLSSVYRP RLAKPEEPSS IWKLFHRQNQ AFNFVKSCKE 
        70         80         90        100        110        120 
SVHVFALECK RGNGQRIYLV TSYAQLWFYY KTRKTLLHCY EVIPENAVCK LYFDLEFNKL 
       130        140        150        160        170        180 
ANPGADGKMM VALLIQHVCK ALEEFYNVQC SAEDVFNLDS STEEKFSRHL IFQLHNVAFK 
       190        200        210        220        230        240 
DNRHAGNFVR KILQPALHLI AEDDEAKVPE AVGQDASGFS VTPLKQEISE AREKVGLPKQ 
       250        260        270        280        290        300 
CDPDLSFLVV KNHMGEKCLF VDLGVYTKNR NFRLYQSSKI GKCVSLEVAE DNRFIPKQSK 
       310        320        330        340        350        360 
DISEENQYFL SSLVSNVRFS DTLRVLTCHP SQTKRKRAEC FNSTGTSVES IEGFQGSPYP 
       370        380        390        400        410        420 
EVDQFVLSLV NKHDIKGGIR RWNYFFPEEL LVYDICKYRW CENIGRAHKS NNIMILVDLK 
       430        440        450        460        470        480 
NEVWYQKCHD PVCKAQNFKS TCSPLPTEVS LLFLLKDEDF TSGETDDTST SLTKDSQTPP 
       490        500        510        520        530    
SCNLSAGGLS AAAWDDEDDA LFLEATEDAE FADAADKSLG SMDDIPDELI IEALQNS

Isoforms

- Isoform 2 of DNA-directed primase/polymerase protein

Sequence View

        10         20         30         40         50         60 
MLRKWEARVK QIEERASHYE RKPLSSVYRP RLAKPEEPSS IWKLFHRQNQ AFNFVKSCKE 
        70         80         90        100        110        120 
SVHVFALECK RGNGQRIYLV TSYAQLWFYY KTRKTLLHCY EVIPENAVCK LYFDLEFNKL 
       130        140        150        160        170        180 
ANPGADGKMM VALLIQHVCK ALEEFYNVQC SAEDVFNLDS STEEKFSRHL IFQLHNVAFK 
       190        200        210        220        230        240 
DNRHAGNFVR KILQPALHLI AEDDEAKVPE AVGQDASGFS VTPLKQEISE AREKVGLPKQ 
       250        260        270        280        290        300 
CDPDLSFLVV KNHMGEKCLF VDLGVYTKNR NFRLYQSSKI GKCVSLEVAE DNRFIPKQSK 
       310        320        330        340        350        360 
DISEENQYFL SSLVSNVRFS DTLRVLTCHP SQTKRKRAEC FNSTGTSVES IEGFQGSPYP 
       370        380        390        400        410        420 
EVDQFVLSLV NKHDIKGGIR RWNYFFPEEL LVYDICKYRW CENIGRAHKS NNIMILVDLK 
       430        440        450        460        470        480 
NEVWYQKCHD PVCKAQNFKS TCSPLPTEVS LLFLLKDEDF TSGETDDTST SLTKDSQTPP 
       490        500        510        520        530    
SCNLSAGGLS AAAWDDEDDA LFLEATEDAE FADAADKSLG SMDDIPDELI IEALQNS



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6P1E7-1-unknown MLRKWE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6P1E7-1-unknown MLRKWE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86203

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ALQNS 537 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)