TopFIND 4.0

Q6P253: Dermokine

General Information

Protein names
- Dermokine
- Epidermis-specific secreted protein SK30/SK89
Gene names Dmkn
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q6P253

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLQGSLACL LLALCLGGGA ANPLHSGGEG TGASAAHGAG DAISHGIGEA VGQGAKEAAS 
        70         80         90        100        110        120 
SGIQNALGQG HGEEGGSTLM GSRGDVFEHR LGEAARSLGN AGNEIGRQAE DIIRQGVDAV 
       130        140        150        160        170        180 
HNAGSWGTSG GHGAYGSQGG AGVQGNPGPQ GTPWASGGNY GTNSLGGSVG QGGNGGPLDY 
       190        200        210        220        230        240 
ETNAQGAVAQ PGYGTVRGNN QNSGCTNPPP SGSHESFSNS GGSSNDGSRG SQGSHGSNGQ 
       250        260        270        280        290        300 
GSSGRGGGQG NSDNNGSSSS SSGSNSGNSN SGNSGNSNSG NSGNSGSGSR DIETSNFDEG 
       310        320        330        340        350        360 
YSVSRGTGSR GGSGGSGGSG GSGGSGGSGG GNKPECNNPG NDVRMAGGSG SQGHGSNGGN 
       370        380        390        400        410        420 
IQKEAVNGLN TMNSDASTLP FNIDNFWENL KSKTRFINWD AINKGHAPSP STRALLYFRK 
       430        440        450        460        470        480 
LWENFKRSTP FFNWKQIEGS DLSSLQKRAG GADQFSKPEA RQDLSADSSK NYYNNQQVNP 
       490        500        510    
TYNWQYYTKT TAKAGVTPSS SSASRAQPGL LKWLKFW

Isoforms

- Isoform 2 of Dermokine - Isoform 3 of Dermokine - Isoform 4 of Dermokine

Sequence View

        10         20         30         40         50         60 
MKLQGSLACL LLALCLGGGA ANPLHSGGEG TGASAAHGAG DAISHGIGEA VGQGAKEAAS 
        70         80         90        100        110        120 
SGIQNALGQG HGEEGGSTLM GSRGDVFEHR LGEAARSLGN AGNEIGRQAE DIIRQGVDAV 
       130        140        150        160        170        180 
HNAGSWGTSG GHGAYGSQGG AGVQGNPGPQ GTPWASGGNY GTNSLGGSVG QGGNGGPLDY 
       190        200        210        220        230        240 
ETNAQGAVAQ PGYGTVRGNN QNSGCTNPPP SGSHESFSNS GGSSNDGSRG SQGSHGSNGQ 
       250        260        270        280        290        300 
GSSGRGGGQG NSDNNGSSSS SSGSNSGNSN SGNSGNSNSG NSGNSGSGSR DIETSNFDEG 
       310        320        330        340        350        360 
YSVSRGTGSR GGSGGSGGSG GSGGSGGSGG GNKPECNNPG NDVRMAGGSG SQGHGSNGGN 
       370        380        390        400        410        420 
IQKEAVNGLN TMNSDASTLP FNIDNFWENL KSKTRFINWD AINKGHAPSP STRALLYFRK 
       430        440        450        460        470        480 
LWENFKRSTP FFNWKQIEGS DLSSLQKRAG GADQFSKPEA RQDLSADSSK NYYNNQQVNP 
       490        500        510    
TYNWQYYTKT TAKAGVTPSS SSASRAQPGL LKWLKFW         10         20         30         40         50         60 
MKLQGSLACL LLALCLGGGA ANPLHSGGEG TGASAAHGAG DAISHGIGEA VGQGAKEAAS 
        70         80         90        100        110        120 
SGIQNALGQG HGEEGGSTLM GSRGDVFEHR LGEAARSLGN AGNEIGRQAE DIIRQGVDAV 
       130        140        150        160        170        180 
HNAGSWGTSG GHGAYGSQGG AGVQGNPGPQ GTPWASGGNY GTNSLGGSVG QGGNGGPLDY 
       190        200        210        220        230        240 
ETNAQGAVAQ PGYGTVRGNN QNSGCTNPPP SGSHESFSNS GGSSNDGSRG SQGSHGSNGQ 
       250        260        270        280        290        300 
GSSGRGGGQG NSDNNGSSSS SSGSNSGNSN SGNSGNSNSG NSGNSGSGSR DIETSNFDEG 
       310        320        330        340        350        360 
YSVSRGTGSR GGSGGSGGSG GSGGSGGSGG GNKPECNNPG NDVRMAGGSG SQGHGSNGGN 
       370        380        390        400        410        420 
IQKEAVNGLN TMNSDASTLP FNIDNFWENL KSKTRFINWD AINKGHAPSP STRALLYFRK 
       430        440        450        460        470        480 
LWENFKRSTP FFNWKQIEGS DLSSLQKRAG GADQFSKPEA RQDLSADSSK NYYNNQQVNP 
       490        500        510    
TYNWQYYTKT TAKAGVTPSS SSASRAQPGL LKWLKFW         10         20         30         40         50         60 
MKLQGSLACL LLALCLGGGA ANPLHSGGEG TGASAAHGAG DAISHGIGEA VGQGAKEAAS 
        70         80         90        100        110        120 
SGIQNALGQG HGEEGGSTLM GSRGDVFEHR LGEAARSLGN AGNEIGRQAE DIIRQGVDAV 
       130        140        150        160        170        180 
HNAGSWGTSG GHGAYGSQGG AGVQGNPGPQ GTPWASGGNY GTNSLGGSVG QGGNGGPLDY 
       190        200        210        220        230        240 
ETNAQGAVAQ PGYGTVRGNN QNSGCTNPPP SGSHESFSNS GGSSNDGSRG SQGSHGSNGQ 
       250        260        270        280        290        300 
GSSGRGGGQG NSDNNGSSSS SSGSNSGNSN SGNSGNSNSG NSGNSGSGSR DIETSNFDEG 
       310        320        330        340        350        360 
YSVSRGTGSR GGSGGSGGSG GSGGSGGSGG GNKPECNNPG NDVRMAGGSG SQGHGSNGGN 
       370        380        390        400        410        420 
IQKEAVNGLN TMNSDASTLP FNIDNFWENL KSKTRFINWD AINKGHAPSP STRALLYFRK 
       430        440        450        460        470        480 
LWENFKRSTP FFNWKQIEGS DLSSLQKRAG GADQFSKPEA RQDLSADSSK NYYNNQQVNP 
       490        500        510    
TYNWQYYTKT TAKAGVTPSS SSASRAQPGL LKWLKFW



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)