TopFIND 4.0

Q6P531: Glutathione hydrolase 6

General Information

Protein names
- Glutathione hydrolase 6
- 3.4.19.13
- Gamma-glutamyltransferase 6
- GGT 6
- 2.3.2.2
- Gamma-glutamyltranspeptidase 6
- Glutathione hydrolase 6 heavy chain
- Glutathione hydrolase 6 light chain
Gene names GGT6
Organism Homo sapiens
Protease Family
Protease ID T03.024
Chromosome location
UniProt ID Q6P531

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MERAEEPVVY QKLLPWEPSL ESEEEVEEEE TSEALVLNPR RHQDSSRNKA GGLPGTWARV 
        70         80         90        100        110        120 
VAALLLLAVG CSLAVRQLQN QGRSTGSLGS VAPPPGGHSH GPGVYHHGAI ISPAGRELLV 
       130        140        150        160        170        180 
AGGNVVDAGV GAALCLAVVH PHATGLGAMF WGLFHDSSSG NSTALTSGPA QTLAPGLGLP 
       190        200        210        220        230        240 
AALPTLHLLH ARFGRLPWPR LLVGPTTLAQ EGFLVDTPLA RALVARGTEG LCPLLCHADG 
       250        260        270        280        290        300 
TPLGAGARAT NPQLAAVLRS AALAPTSDLA GDALLSLLAG DLGVEVPSAV PRPTLEPAEQ 
       310        320        330        340        350        360 
LPVPQGILFT TPSPSAGPEL LALLEAALRS GAPIPDPCPP FLQTAVSPES SALAAVDSSG 
       370        380        390        400        410        420 
SVLLLTSSLN CSFGSAHLSP STGVLLSNLV AKSTTSAWAC PLILRGSLDD TEADVLGLVA 
       430        440        450        460        470        480 
SGTPDVARAM THTLLRHLAA RPPTQAQHQH QGQQEPTEHP STCGQGTLLQ VAAHTEHAHV 
       490    
SSVPHACCPF QGF

Isoforms

- Isoform 2 of Gamma-glutamyltransferase 6 - Isoform 2 of Glutathione hydrolase 6

Sequence View

        10         20         30         40         50         60 
MERAEEPVVY QKLLPWEPSL ESEEEVEEEE TSEALVLNPR RHQDSSRNKA GGLPGTWARV 
        70         80         90        100        110        120 
VAALLLLAVG CSLAVRQLQN QGRSTGSLGS VAPPPGGHSH GPGVYHHGAI ISPAGRELLV 
       130        140        150        160        170        180 
AGGNVVDAGV GAALCLAVVH PHATGLGAMF WGLFHDSSSG NSTALTSGPA QTLAPGLGLP 
       190        200        210        220        230        240 
AALPTLHLLH ARFGRLPWPR LLVGPTTLAQ EGFLVDTPLA RALVARGTEG LCPLLCHADG 
       250        260        270        280        290        300 
TPLGAGARAT NPQLAAVLRS AALAPTSDLA GDALLSLLAG DLGVEVPSAV PRPTLEPAEQ 
       310        320        330        340        350        360 
LPVPQGILFT TPSPSAGPEL LALLEAALRS GAPIPDPCPP FLQTAVSPES SALAAVDSSG 
       370        380        390        400        410        420 
SVLLLTSSLN CSFGSAHLSP STGVLLSNLV AKSTTSAWAC PLILRGSLDD TEADVLGLVA 
       430        440        450        460        470        480 
SGTPDVARAM THTLLRHLAA RPPTQAQHQH QGQQEPTEHP STCGQGTLLQ VAAHTEHAHV 
       490    
SSVPHACCPF QGF         10         20         30         40         50         60 
MERAEEPVVY QKLLPWEPSL ESEEEVEEEE TSEALVLNPR RHQDSSRNKA GGLPGTWARV 
        70         80         90        100        110        120 
VAALLLLAVG CSLAVRQLQN QGRSTGSLGS VAPPPGGHSH GPGVYHHGAI ISPAGRELLV 
       130        140        150        160        170        180 
AGGNVVDAGV GAALCLAVVH PHATGLGAMF WGLFHDSSSG NSTALTSGPA QTLAPGLGLP 
       190        200        210        220        230        240 
AALPTLHLLH ARFGRLPWPR LLVGPTTLAQ EGFLVDTPLA RALVARGTEG LCPLLCHADG 
       250        260        270        280        290        300 
TPLGAGARAT NPQLAAVLRS AALAPTSDLA GDALLSLLAG DLGVEVPSAV PRPTLEPAEQ 
       310        320        330        340        350        360 
LPVPQGILFT TPSPSAGPEL LALLEAALRS GAPIPDPCPP FLQTAVSPES SALAAVDSSG 
       370        380        390        400        410        420 
SVLLLTSSLN CSFGSAHLSP STGVLLSNLV AKSTTSAWAC PLILRGSLDD TEADVLGLVA 
       430        440        450        460        470        480 
SGTPDVARAM THTLLRHLAA RPPTQAQHQH QGQQEPTEHP STCGQGTLLQ VAAHTEHAHV 
       490    
SSVPHACCPF QGF



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6P531-0-unknown FMERAE... 0 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6P531-1-unknown MERAEE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6P531-1-unknown MERAEE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75952

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)