TopFIND 4.0

Q6P720: Rho guanine nucleotide exchange factor 25

General Information

Protein names
- Rho guanine nucleotide exchange factor 25
- Guanine nucleotide exchange factor GEFT
- Rac/Cdc42/Rho exchange factor GEFT
- RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT
Gene names Arhgef25
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q6P720

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKPPDRPTPG RTDRILGVMG GMLRACAVPG QEGPQERDPL GPGSTKTESE CTEEDQTGER 
        70         80         90        100        110        120 
EREVLAWAPQ PESYSIAGSE GSMSASAVSG LAALSGPSSG LSSHPCSPVP PGPVTGLRRW 
       130        140        150        160        170        180 
LDHSKHCLSV ETEADSGQTR QCENWMLEPT LTTGQELPEL TLLTTLLEGP GVKAQPAEEE 
       190        200        210        220        230        240 
TLSQAPKNEE EQKKTALERS MFVLSELVET ERMYVDDLGQ IVEGYMATMA TQGVPESLRG 
       250        260        270        280        290        300 
RDRIVFGNIQ QIYEWHRDYF LQELQQCLKD PDWLAQLFIK HERRLHMYVV YCQNKPKSEH 
       310        320        330        340        350        360 
VLSEFGDSYF EELRQQLGHR LQLSDLLIKP VQRIMKYQLL LKDFLKYYRR AGMDTEELEQ 
       370        380        390        400        410        420 
AVEVMCFVPK RCNDMMSLGR LRGFEGKLTA QGKLLGQDTF LVTEPEAGGL LSSRGRERRV 
       430        440        450        460        470        480 
FLFEQIVIFS EALGGGGRGG TQPGYVYKNS IKASDPAVSQ AWIKQVAQIL ESQRDFLNAL 
       490        500        510        520        530        540 
QSPIEYQRRE SQTNSLGRSG GPGVGSPGRM AQVSMHTPIN GSLPSLLLLP RGEVPRAPLP 
       550        560        570    
LDTQALSETP LTPYDPPALP TVNSPPGQAR LAKLDEDEL

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6P720-1-unknown MKPPDR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DEDEL 579 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)