TopFIND 4.0

Q6PCB0: von Willebrand factor A domain-containing protein 1

General Information

Protein names
- von Willebrand factor A domain-containing protein 1
Gene names VWA1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6PCB0

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLPWTALGLA LSLRLALARS GAERGPPASA PRGDLMFLLD SSASVSHYEF SRVREFVGQL 
        70         80         90        100        110        120 
VAPLPLGTGA LRASLVHVGS RPYTEFPFGQ HSSGEAAQDA VRASAQRMGD THTGLALVYA 
       130        140        150        160        170        180 
KEQLFAEASG ARPGVPKVLV WVTDGGSSDP VGPPMQELKD LGVTVFIVST GRGNFLELSA 
       190        200        210        220        230        240 
AASAPAEKHL HFVDVDDLHI IVQELRGSIL DAMRPQQLHA TEITSSGFRL AWPPLLTADS 
       250        260        270        280        290        300 
GYYVLELVPS AQPGAARRQQ LPGNATDWIW AGLDPDTDYD VALVPESNVR LLRPQILRVR 
       310        320        330        340        350        360 
TRPGEAGPGA SGPESGAGPA PTQLAALPAP EEAGPERIVI SHARPRSLRV SWAPALGSAA 
       370        380        390        400        410        420 
ALGYHVQFGP LRGGEAQRVE VPAGRNCTTL QGLAPGTAYL VTVTAAFRSG RESALSAKAC 
       430        440    
TPDGPRPRPR PVPRAPTPGT ASREP

Isoforms

- Isoform 2 of von Willebrand factor A domain-containing protein 1 - Isoform 3 of von Willebrand factor A domain-containing protein 1

Sequence View

        10         20         30         40         50         60 
MLPWTALGLA LSLRLALARS GAERGPPASA PRGDLMFLLD SSASVSHYEF SRVREFVGQL 
        70         80         90        100        110        120 
VAPLPLGTGA LRASLVHVGS RPYTEFPFGQ HSSGEAAQDA VRASAQRMGD THTGLALVYA 
       130        140        150        160        170        180 
KEQLFAEASG ARPGVPKVLV WVTDGGSSDP VGPPMQELKD LGVTVFIVST GRGNFLELSA 
       190        200        210        220        230        240 
AASAPAEKHL HFVDVDDLHI IVQELRGSIL DAMRPQQLHA TEITSSGFRL AWPPLLTADS 
       250        260        270        280        290        300 
GYYVLELVPS AQPGAARRQQ LPGNATDWIW AGLDPDTDYD VALVPESNVR LLRPQILRVR 
       310        320        330        340        350        360 
TRPGEAGPGA SGPESGAGPA PTQLAALPAP EEAGPERIVI SHARPRSLRV SWAPALGSAA 
       370        380        390        400        410        420 
ALGYHVQFGP LRGGEAQRVE VPAGRNCTTL QGLAPGTAYL VTVTAAFRSG RESALSAKAC 
       430        440    
TPDGPRPRPR PVPRAPTPGT ASREP         10         20         30         40         50         60 
MLPWTALGLA LSLRLALARS GAERGPPASA PRGDLMFLLD SSASVSHYEF SRVREFVGQL 
        70         80         90        100        110        120 
VAPLPLGTGA LRASLVHVGS RPYTEFPFGQ HSSGEAAQDA VRASAQRMGD THTGLALVYA 
       130        140        150        160        170        180 
KEQLFAEASG ARPGVPKVLV WVTDGGSSDP VGPPMQELKD LGVTVFIVST GRGNFLELSA 
       190        200        210        220        230        240 
AASAPAEKHL HFVDVDDLHI IVQELRGSIL DAMRPQQLHA TEITSSGFRL AWPPLLTADS 
       250        260        270        280        290        300 
GYYVLELVPS AQPGAARRQQ LPGNATDWIW AGLDPDTDYD VALVPESNVR LLRPQILRVR 
       310        320        330        340        350        360 
TRPGEAGPGA SGPESGAGPA PTQLAALPAP EEAGPERIVI SHARPRSLRV SWAPALGSAA 
       370        380        390        400        410        420 
ALGYHVQFGP LRGGEAQRVE VPAGRNCTTL QGLAPGTAYL VTVTAAFRSG RESALSAKAC 
       430        440    
TPDGPRPRPR PVPRAPTPGT ASREP



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(REFRESH)

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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6PCB0-1-unknown MLPWTA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94346
    Q6PCB0-23-unknown ERGPPA... 23 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6PCB0-213-unknown MRPQQL... 213 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94345

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ASREP 445 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ASREP 445 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89963

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)