Q6PCD5: E3 ubiquitin-protein ligase RFWD3 {ECO:0000305}

General Information

Protein names	- E3 ubiquitin-protein ligase RFWD3 {ECO:0000305} - 2.3.2.27 {ECO:0000269\|PubMed:26474068, ECO:0000269\|PubMed:28575657, ECO:0000269\|PubMed:28575658} - RING finger and WD repeat domain-containing protein 3 - RING finger protein 201
Gene names	RFWD3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6PCD5

2 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAHEAMEYDV QVQLNHAEQQ PAPAGMASSQ GGPALLQPVP ADVVSSQGVP SILQPAPAEV
        70         80         90        100        110        120
ISSQATPPLL QPAPQLSVDL TEVEVLGEDT VENINPRTSE QHRQGSDGNH TIPASSLHSM
       130        140        150        160        170        180
TNFISGLQRL HGMLEFLRPS SSNHSVGPMR TRRRVSASRR ARAGGSQRTD SARLRAPLDA
       190        200        210        220        230        240
YFQVSRTQPD LPATTYDSET RNPVSEELQV SSSSDSDSDS SAEYGGVVDQ AEESGAVILE
       250        260        270        280        290        300
EQLAGVSAEQ EVTCIDGGKT LPKQPSPQKS EPLLPSASMD EEEGDTCTIC LEQWTNAGDH
       310        320        330        340        350        360
RLSALRCGHL FGYRCISTWL KGQVRKCPQC NKKARHSDIV VLYARTLRAL DTSEQERMKS
       370        380        390        400        410        420
SLLKEQMLRK QAELESAQCR LQLQVLTDKC TRLQRRVQDL QKLTSHQSQN LQQPRGSQAW
       430        440        450        460        470        480
VLSCSPSSQG QHKHKYHFQK TFTVSQAGNC RIMAYCDALS CLVISQPSPQ ASFLPGFGVK
       490        500        510        520        530        540
MLSTANMKSS QYIPMHGKQI RGLAFSSYLR GLLLSASLDN TIKLTSLETN TVVQTYNAGR
       550        560        570        580        590        600
PVWSCCWCLD EANYIYAGLA NGSILVYDVR NTSSHVQELV AQKARCPLVS LSYMPRAASA
       610        620        630        640        650        660
AFPYGGVLAG TLEDASFWEQ KMDFSHWPHV LPLEPGGCID FQTENSSRHC LVTYRPDKNH
       670        680        690        700        710        720
TTIRSVLMEM SYRLDDTGNP ICSCQPVHTF FGGPTCKLLT KNAIFQSPEN DGNILVCTGD
       730        740        750        760        770
EAANSALLWD AASGSLLQDL QTDQPVLDIC PFEVNRNSYL ATLTEKMVHI YKWE

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6PCD5-1-unknown	MAHEAM...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6PCD5-279-unknown	MDEEEG...	279		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000459465

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IPASSL	116	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000461285
...HSMTNF	122	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000459515
...VGPMRT	150	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000459899
...GDHRLS	302	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000459465
...IYKWE	774	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)