Q6PDI5: Proteasome adapter and scaffold protein ECM29 {ECO:0000250|UniProtKB:Q5VYK3}
| Protein names | - Proteasome adapter and scaffold protein ECM29 {ECO:0000250|UniProtKB:Q5VYK3} - Proteasome-associated protein ECM29 homolog |
|---|---|
| Gene names | Ecm29 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q6PDI5 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
METGSDSDQL ERVFLRLGHA ETDEQLQNII SKFLPPVLLK LSSTQEGVRK KVMELLVHLN
70 80 90 100 110 120
KRIKSRPKIQ LPVETLLVQY QDPAAVSFVT NFTIIYVKMG YPRLPVEKQC ELAPTLLTAM
130 140 150 160 170 180
EGKPQPQQDS LMHLLIPTLF HMKYPAESSK SASPFNLAEK PKTVQLLLDF MLDVLLMPYG
190 200 210 220 230 240
YVLNESQSRQ NSSSSSQGSS SNSGGGSGIP QPPPGMSFYA AKRVIGDNPW TPEQLEQCKL
250 260 270 280 290 300
GIVKFIEAEQ VPELEAVLHL VIASSDTRHS VATAADLELK SKQSLIDWNN PAIINKMYKV
310 320 330 340 350 360
YLGDIPLKTK EGAVLKPELK RDPVSTRVKL KIVPHLLRSR QAAETFPANI QVVYDGLFGT
370 380 390 400 410 420
NTNSKLRTLS LQFVHHICLT CPEIKIKPLG PMLLNGLTKL INEYKEDPKL LSMAYSAVGK
430 440 450 460 470 480
LSSRMPHLFT KDIALVQQLF EALCKEEPET RLAIQEALSM MVGAYSTLEG AQRTLMEALV
490 500 510 520 530 540
ASYLIKPEVQ VRQVAVKFAS TVFPSDHIPS RYLLLLAAGD PREEVHGEAQ RVLRCLPGRN
550 560 570 580 590 600
KKESASKQMP SFPEMVYYIQ EKASHRMKTP VKYMTGTTVL PFNPAAFGEI VLYLRMCLAH
610 620 630 640 650 660
SAGVVPTSQS LADMQDHAPA IGRYIRALMS SSQATASSSN KSGETNPVQI YTGLLQQLLA
670 680 690 700 710 720
GVGGLPVMYC LLEAVSVYPE KLATKFVDKT EWIKSLMSSS KEEMRELAAL FYSVVVSTVS
730 740 750 760 770 780
GIELKSMIEQ LIKATKDNHS PEVQHGSLLA LGFTVGRYLA KKRVRMAEQH DLETDADLLP
790 800 810 820 830 840
EQEEIIRSAT ETIGSFLDST SPLLAIAACT ALGEIGRNGP LPIPSEGSGF TKLHLVESLL
850 860 870 880 890 900
NRIPSSKETN KMKERAIQTL GYFPVGDGVF PHQKLLLQGL MDSVEAKQIE LQFTIGEAIT
910 920 930 940 950 960
SAAIGTNSVA ARDAWLVTEE EYIPPAGAKV NDVVPWVLDV ILNKHIISPN PHVRQAACIW
970 980 990 1000 1010 1020
LLSLVRKLST HREVKSHLKE IQSAFVSVLS ENDELSQDVA SKGLGLVYEL GNEQDQQELV
1030 1040 1050 1060 1070 1080
STLVETLMTG KRVKHEVSGE TVVFQGGGLG KTPDGQGLST YKELCSLASD LSQPDLVYKF
1090 1100 1110 1120 1130 1140
MNLANHHAMW NSRKGAAFGF NVIATRAGEQ LAPFLPQLVP RLYRYQFDPN LGIRQAMTSI
1150 1160 1170 1180 1190 1200
WNALVTDKSM VDKYLKEILQ DLIKNLTSNM WRVRESSCLA LNDLLRGRPL DDVIDKLPEM
1210 1220 1230 1240 1250 1260
WETLFRVQDD IKESVRKAAE LALKTLSKVC VKMCDPAKGA AGQRTIAVLL PCLLDKGMMS
1270 1280 1290 1300 1310 1320
PVTEVRALSI NTLVKISKSA GAMLKPHAPK LIPALLESLS VLEPQVLNYL SLRATEQEKD
1330 1340 1350 1360 1370 1380
VMDSARLSAA KSSPMMETIN MCLQYLDVSV LGELVPRLCE LIRSGVGLGT KGGCASVIVS
1390 1400 1410 1420 1430 1440
LTTQCPQDLT PYSGKLMSAL LSGLTDRNSV IQKSCAFAMG HLVRTSRDSS TEKLLQKLNG
1450 1460 1470 1480 1490 1500
WYMEKDEPVY KTSCALTIHA IGRYSPDVLK NHAKEVLPLA FLGMHEIADE EKSEKEECNM
1510 1520 1530 1540 1550 1560
WTEVWQENVP GSFGGIRLYL QELITITQKA LQSQSWKMKA QGAIAMASIS KQTSSLVPPY
1570 1580 1590 1600 1610 1620
LGMILSALMQ GLAGRTWAGK EELLKAIACV VTACSTELEK SVPNQPTTNE ILQAVLKECC
1630 1640 1650 1660 1670 1680
KENLKYKIVA ISCAADVLKA TKEDRFQEFS DIVIPLIKKN SLESMGVRTT KAEDENEKER
1690 1700 1710 1720 1730 1740
ELQLESLLGA FESLGKAWPR NPDTQRCYRQ ELCKLMCERL RLSTWKVQLG VLQSMNAFFQ
1750 1760 1770 1780 1790 1800
GLMLLEEEHA DPEALAEILL ETCKSITYSL ENKTYSSVRT EALSVVELLL KKLEEAKQWE
1810 1820 1830 1840
SLTAECRGLL IESLATMETD NRPELQEKAS VLKKTLESLE
Isoforms
- Isoform 2 of Proteasome-associated protein ECM29 homolog - Isoform 2 of Proteasome adapter and scaffold protein ECM29Sequence View
10 20 30 40 50 60
METGSDSDQL ERVFLRLGHA ETDEQLQNII SKFLPPVLLK LSSTQEGVRK KVMELLVHLN
70 80 90 100 110 120
KRIKSRPKIQ LPVETLLVQY QDPAAVSFVT NFTIIYVKMG YPRLPVEKQC ELAPTLLTAM
130 140 150 160 170 180
EGKPQPQQDS LMHLLIPTLF HMKYPAESSK SASPFNLAEK PKTVQLLLDF MLDVLLMPYG
190 200 210 220 230 240
YVLNESQSRQ NSSSSSQGSS SNSGGGSGIP QPPPGMSFYA AKRVIGDNPW TPEQLEQCKL
250 260 270 280 290 300
GIVKFIEAEQ VPELEAVLHL VIASSDTRHS VATAADLELK SKQSLIDWNN PAIINKMYKV
310 320 330 340 350 360
YLGDIPLKTK EGAVLKPELK RDPVSTRVKL KIVPHLLRSR QAAETFPANI QVVYDGLFGT
370 380 390 400 410 420
NTNSKLRTLS LQFVHHICLT CPEIKIKPLG PMLLNGLTKL INEYKEDPKL LSMAYSAVGK
430 440 450 460 470 480
LSSRMPHLFT KDIALVQQLF EALCKEEPET RLAIQEALSM MVGAYSTLEG AQRTLMEALV
490 500 510 520 530 540
ASYLIKPEVQ VRQVAVKFAS TVFPSDHIPS RYLLLLAAGD PREEVHGEAQ RVLRCLPGRN
550 560 570 580 590 600
KKESASKQMP SFPEMVYYIQ EKASHRMKTP VKYMTGTTVL PFNPAAFGEI VLYLRMCLAH
610 620 630 640 650 660
SAGVVPTSQS LADMQDHAPA IGRYIRALMS SSQATASSSN KSGETNPVQI YTGLLQQLLA
670 680 690 700 710 720
GVGGLPVMYC LLEAVSVYPE KLATKFVDKT EWIKSLMSSS KEEMRELAAL FYSVVVSTVS
730 740 750 760 770 780
GIELKSMIEQ LIKATKDNHS PEVQHGSLLA LGFTVGRYLA KKRVRMAEQH DLETDADLLP
790 800 810 820 830 840
EQEEIIRSAT ETIGSFLDST SPLLAIAACT ALGEIGRNGP LPIPSEGSGF TKLHLVESLL
850 860 870 880 890 900
NRIPSSKETN KMKERAIQTL GYFPVGDGVF PHQKLLLQGL MDSVEAKQIE LQFTIGEAIT
910 920 930 940 950 960
SAAIGTNSVA ARDAWLVTEE EYIPPAGAKV NDVVPWVLDV ILNKHIISPN PHVRQAACIW
970 980 990 1000 1010 1020
LLSLVRKLST HREVKSHLKE IQSAFVSVLS ENDELSQDVA SKGLGLVYEL GNEQDQQELV
1030 1040 1050 1060 1070 1080
STLVETLMTG KRVKHEVSGE TVVFQGGGLG KTPDGQGLST YKELCSLASD LSQPDLVYKF
1090 1100 1110 1120 1130 1140
MNLANHHAMW NSRKGAAFGF NVIATRAGEQ LAPFLPQLVP RLYRYQFDPN LGIRQAMTSI
1150 1160 1170 1180 1190 1200
WNALVTDKSM VDKYLKEILQ DLIKNLTSNM WRVRESSCLA LNDLLRGRPL DDVIDKLPEM
1210 1220 1230 1240 1250 1260
WETLFRVQDD IKESVRKAAE LALKTLSKVC VKMCDPAKGA AGQRTIAVLL PCLLDKGMMS
1270 1280 1290 1300 1310 1320
PVTEVRALSI NTLVKISKSA GAMLKPHAPK LIPALLESLS VLEPQVLNYL SLRATEQEKD
1330 1340 1350 1360 1370 1380
VMDSARLSAA KSSPMMETIN MCLQYLDVSV LGELVPRLCE LIRSGVGLGT KGGCASVIVS
1390 1400 1410 1420 1430 1440
LTTQCPQDLT PYSGKLMSAL LSGLTDRNSV IQKSCAFAMG HLVRTSRDSS TEKLLQKLNG
1450 1460 1470 1480 1490 1500
WYMEKDEPVY KTSCALTIHA IGRYSPDVLK NHAKEVLPLA FLGMHEIADE EKSEKEECNM
1510 1520 1530 1540 1550 1560
WTEVWQENVP GSFGGIRLYL QELITITQKA LQSQSWKMKA QGAIAMASIS KQTSSLVPPY
1570 1580 1590 1600 1610 1620
LGMILSALMQ GLAGRTWAGK EELLKAIACV VTACSTELEK SVPNQPTTNE ILQAVLKECC
1630 1640 1650 1660 1670 1680
KENLKYKIVA ISCAADVLKA TKEDRFQEFS DIVIPLIKKN SLESMGVRTT KAEDENEKER
1690 1700 1710 1720 1730 1740
ELQLESLLGA FESLGKAWPR NPDTQRCYRQ ELCKLMCERL RLSTWKVQLG VLQSMNAFFQ
1750 1760 1770 1780 1790 1800
GLMLLEEEHA DPEALAEILL ETCKSITYSL ENKTYSSVRT EALSVVELLL KKLEEAKQWE
1810 1820 1830 1840
SLTAECRGLL IESLATMETD NRPELQEKAS VLKKTLESLE
10 20 30 40 50 60
METGSDSDQL ERVFLRLGHA ETDEQLQNII SKFLPPVLLK LSSTQEGVRK KVMELLVHLN
70 80 90 100 110 120
KRIKSRPKIQ LPVETLLVQY QDPAAVSFVT NFTIIYVKMG YPRLPVEKQC ELAPTLLTAM
130 140 150 160 170 180
EGKPQPQQDS LMHLLIPTLF HMKYPAESSK SASPFNLAEK PKTVQLLLDF MLDVLLMPYG
190 200 210 220 230 240
YVLNESQSRQ NSSSSSQGSS SNSGGGSGIP QPPPGMSFYA AKRVIGDNPW TPEQLEQCKL
250 260 270 280 290 300
GIVKFIEAEQ VPELEAVLHL VIASSDTRHS VATAADLELK SKQSLIDWNN PAIINKMYKV
310 320 330 340 350 360
YLGDIPLKTK EGAVLKPELK RDPVSTRVKL KIVPHLLRSR QAAETFPANI QVVYDGLFGT
370 380 390 400 410 420
NTNSKLRTLS LQFVHHICLT CPEIKIKPLG PMLLNGLTKL INEYKEDPKL LSMAYSAVGK
430 440 450 460 470 480
LSSRMPHLFT KDIALVQQLF EALCKEEPET RLAIQEALSM MVGAYSTLEG AQRTLMEALV
490 500 510 520 530 540
ASYLIKPEVQ VRQVAVKFAS TVFPSDHIPS RYLLLLAAGD PREEVHGEAQ RVLRCLPGRN
550 560 570 580 590 600
KKESASKQMP SFPEMVYYIQ EKASHRMKTP VKYMTGTTVL PFNPAAFGEI VLYLRMCLAH
610 620 630 640 650 660
SAGVVPTSQS LADMQDHAPA IGRYIRALMS SSQATASSSN KSGETNPVQI YTGLLQQLLA
670 680 690 700 710 720
GVGGLPVMYC LLEAVSVYPE KLATKFVDKT EWIKSLMSSS KEEMRELAAL FYSVVVSTVS
730 740 750 760 770 780
GIELKSMIEQ LIKATKDNHS PEVQHGSLLA LGFTVGRYLA KKRVRMAEQH DLETDADLLP
790 800 810 820 830 840
EQEEIIRSAT ETIGSFLDST SPLLAIAACT ALGEIGRNGP LPIPSEGSGF TKLHLVESLL
850 860 870 880 890 900
NRIPSSKETN KMKERAIQTL GYFPVGDGVF PHQKLLLQGL MDSVEAKQIE LQFTIGEAIT
910 920 930 940 950 960
SAAIGTNSVA ARDAWLVTEE EYIPPAGAKV NDVVPWVLDV ILNKHIISPN PHVRQAACIW
970 980 990 1000 1010 1020
LLSLVRKLST HREVKSHLKE IQSAFVSVLS ENDELSQDVA SKGLGLVYEL GNEQDQQELV
1030 1040 1050 1060 1070 1080
STLVETLMTG KRVKHEVSGE TVVFQGGGLG KTPDGQGLST YKELCSLASD LSQPDLVYKF
1090 1100 1110 1120 1130 1140
MNLANHHAMW NSRKGAAFGF NVIATRAGEQ LAPFLPQLVP RLYRYQFDPN LGIRQAMTSI
1150 1160 1170 1180 1190 1200
WNALVTDKSM VDKYLKEILQ DLIKNLTSNM WRVRESSCLA LNDLLRGRPL DDVIDKLPEM
1210 1220 1230 1240 1250 1260
WETLFRVQDD IKESVRKAAE LALKTLSKVC VKMCDPAKGA AGQRTIAVLL PCLLDKGMMS
1270 1280 1290 1300 1310 1320
PVTEVRALSI NTLVKISKSA GAMLKPHAPK LIPALLESLS VLEPQVLNYL SLRATEQEKD
1330 1340 1350 1360 1370 1380
VMDSARLSAA KSSPMMETIN MCLQYLDVSV LGELVPRLCE LIRSGVGLGT KGGCASVIVS
1390 1400 1410 1420 1430 1440
LTTQCPQDLT PYSGKLMSAL LSGLTDRNSV IQKSCAFAMG HLVRTSRDSS TEKLLQKLNG
1450 1460 1470 1480 1490 1500
WYMEKDEPVY KTSCALTIHA IGRYSPDVLK NHAKEVLPLA FLGMHEIADE EKSEKEECNM
1510 1520 1530 1540 1550 1560
WTEVWQENVP GSFGGIRLYL QELITITQKA LQSQSWKMKA QGAIAMASIS KQTSSLVPPY
1570 1580 1590 1600 1610 1620
LGMILSALMQ GLAGRTWAGK EELLKAIACV VTACSTELEK SVPNQPTTNE ILQAVLKECC
1630 1640 1650 1660 1670 1680
KENLKYKIVA ISCAADVLKA TKEDRFQEFS DIVIPLIKKN SLESMGVRTT KAEDENEKER
1690 1700 1710 1720 1730 1740
ELQLESLLGA FESLGKAWPR NPDTQRCYRQ ELCKLMCERL RLSTWKVQLG VLQSMNAFFQ
1750 1760 1770 1780 1790 1800
GLMLLEEEHA DPEALAEILL ETCKSITYSL ENKTYSSVRT EALSVVELLL KKLEEAKQWE
1810 1820 1830 1840
SLTAECRGLL IESLATMETD NRPELQEKAS VLKKTLESLE
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q6PDI5-1-unknown | METGSD... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q6PDI5-39-unknown | LKLSST... | 39 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30623 | |||
| Q6PDI5-39-unknown | LKLSST... | 39 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt138274 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LPPVLL | 38 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30623 | |||
| ...LPPVLL | 38 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt121306 | |||
| ...LESLE | 1840 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...LESLE | 1840 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt69220 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CATE_MOUSE | 38 | PVLL.|.LKLS | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> ECM29_MOUSE @38 |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|