TopFIND 4.0

Q6PDI6: Ubiquitin carboxyl-terminal hydrolase MINDY-2

General Information

Protein names
- Ubiquitin carboxyl-terminal hydrolase MINDY-2
- 3.4.19.12
- Deubiquitinating enzyme MINDY-2
- Protein FAM63B
Gene names Fam63b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q6PDI6

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MENSPDSPQP LELGVAAGRV SPPEGRRRGG REAEDGPAGR AVDSGGQGAA AAAARSSLGD 
        70         80         90        100        110        120 
PTSPSQLGCG AGSDLKDGAS SSPAASEVPS RGQHKVTASP ELAEAAAGRG SGPVGDTGTC 
       130        140        150        160        170        180 
RVEQAAEEPS STGAPSSSCS EPSPPGDSPS LDSLESFSNL HSFPSSSEFN SEEGAETRVP 
       190        200        210        220        230        240 
EDVEEGAAGP PRAAPLCKEE EEDPAQVLAA SKERFPGQSV YHIKWIQWKE ENTPIITQNE 
       250        260        270        280        290        300 
NGPCPLLAIL NVLLLAWKVK LPPMMEIITA EQLMEYLGDY MLEAKPKEIS EIQRVNYEQN 
       310        320        330        340        350        360 
MSDAMAILHK LQTGLDVNVR FTGVRVFEYT PECIVFDLLD IPLYHGWLVD PQIDDIVKAV 
       370        380        390        400        410        420 
GNCSYNQLVE KIISCKQSDN SQLVSEGFVA EQFLNNTATQ LTYHGLCELT STVQEGELCV 
       430        440        450        460        470        480 
FFRNNHFSTM TKYKGQLYLL VTDQGFLTEE KIVWESLHNV DGDGNFCDSE FHLRPPSDPE 
       490        500        510        520        530        540 
TVYKGQQDQI DQDYLMALSL QQEQQSQEIN WEQIPEGISD LELAKKLQEE EDRRASQYYQ 
       550        560        570        580        590        600 
EQEQAQAVVT TTTPSTQAQQ GQPAQASPSS IKQPGNSERK RKEPREKDKE KEKEKNSCVI 
   
L

Isoforms

- Isoform 2 of Protein FAM63B - Isoform 3 of Protein FAM63B - Isoform 2 of Ubiquitin carboxyl-terminal hydrolase MINDY-2 - Isoform 3 of Ubiquitin carboxyl-terminal hydrolase MINDY-2

Sequence View

        10         20         30         40         50         60 
MENSPDSPQP LELGVAAGRV SPPEGRRRGG REAEDGPAGR AVDSGGQGAA AAAARSSLGD 
        70         80         90        100        110        120 
PTSPSQLGCG AGSDLKDGAS SSPAASEVPS RGQHKVTASP ELAEAAAGRG SGPVGDTGTC 
       130        140        150        160        170        180 
RVEQAAEEPS STGAPSSSCS EPSPPGDSPS LDSLESFSNL HSFPSSSEFN SEEGAETRVP 
       190        200        210        220        230        240 
EDVEEGAAGP PRAAPLCKEE EEDPAQVLAA SKERFPGQSV YHIKWIQWKE ENTPIITQNE 
       250        260        270        280        290        300 
NGPCPLLAIL NVLLLAWKVK LPPMMEIITA EQLMEYLGDY MLEAKPKEIS EIQRVNYEQN 
       310        320        330        340        350        360 
MSDAMAILHK LQTGLDVNVR FTGVRVFEYT PECIVFDLLD IPLYHGWLVD PQIDDIVKAV 
       370        380        390        400        410        420 
GNCSYNQLVE KIISCKQSDN SQLVSEGFVA EQFLNNTATQ LTYHGLCELT STVQEGELCV 
       430        440        450        460        470        480 
FFRNNHFSTM TKYKGQLYLL VTDQGFLTEE KIVWESLHNV DGDGNFCDSE FHLRPPSDPE 
       490        500        510        520        530        540 
TVYKGQQDQI DQDYLMALSL QQEQQSQEIN WEQIPEGISD LELAKKLQEE EDRRASQYYQ 
       550        560        570        580        590        600 
EQEQAQAVVT TTTPSTQAQQ GQPAQASPSS IKQPGNSERK RKEPREKDKE KEKEKNSCVI 
   
L         10         20         30         40         50         60 
MENSPDSPQP LELGVAAGRV SPPEGRRRGG REAEDGPAGR AVDSGGQGAA AAAARSSLGD 
        70         80         90        100        110        120 
PTSPSQLGCG AGSDLKDGAS SSPAASEVPS RGQHKVTASP ELAEAAAGRG SGPVGDTGTC 
       130        140        150        160        170        180 
RVEQAAEEPS STGAPSSSCS EPSPPGDSPS LDSLESFSNL HSFPSSSEFN SEEGAETRVP 
       190        200        210        220        230        240 
EDVEEGAAGP PRAAPLCKEE EEDPAQVLAA SKERFPGQSV YHIKWIQWKE ENTPIITQNE 
       250        260        270        280        290        300 
NGPCPLLAIL NVLLLAWKVK LPPMMEIITA EQLMEYLGDY MLEAKPKEIS EIQRVNYEQN 
       310        320        330        340        350        360 
MSDAMAILHK LQTGLDVNVR FTGVRVFEYT PECIVFDLLD IPLYHGWLVD PQIDDIVKAV 
       370        380        390        400        410        420 
GNCSYNQLVE KIISCKQSDN SQLVSEGFVA EQFLNNTATQ LTYHGLCELT STVQEGELCV 
       430        440        450        460        470        480 
FFRNNHFSTM TKYKGQLYLL VTDQGFLTEE KIVWESLHNV DGDGNFCDSE FHLRPPSDPE 
       490        500        510        520        530        540 
TVYKGQQDQI DQDYLMALSL QQEQQSQEIN WEQIPEGISD LELAKKLQEE EDRRASQYYQ 
       550        560        570        580        590        600 
EQEQAQAVVT TTTPSTQAQQ GQPAQASPSS IKQPGNSERK RKEPREKDKE KEKEKNSCVI 
   
L         10         20         30         40         50         60 
MENSPDSPQP LELGVAAGRV SPPEGRRRGG REAEDGPAGR AVDSGGQGAA AAAARSSLGD 
        70         80         90        100        110        120 
PTSPSQLGCG AGSDLKDGAS SSPAASEVPS RGQHKVTASP ELAEAAAGRG SGPVGDTGTC 
       130        140        150        160        170        180 
RVEQAAEEPS STGAPSSSCS EPSPPGDSPS LDSLESFSNL HSFPSSSEFN SEEGAETRVP 
       190        200        210        220        230        240 
EDVEEGAAGP PRAAPLCKEE EEDPAQVLAA SKERFPGQSV YHIKWIQWKE ENTPIITQNE 
       250        260        270        280        290        300 
NGPCPLLAIL NVLLLAWKVK LPPMMEIITA EQLMEYLGDY MLEAKPKEIS EIQRVNYEQN 
       310        320        330        340        350        360 
MSDAMAILHK LQTGLDVNVR FTGVRVFEYT PECIVFDLLD IPLYHGWLVD PQIDDIVKAV 
       370        380        390        400        410        420 
GNCSYNQLVE KIISCKQSDN SQLVSEGFVA EQFLNNTATQ LTYHGLCELT STVQEGELCV 
       430        440        450        460        470        480 
FFRNNHFSTM TKYKGQLYLL VTDQGFLTEE KIVWESLHNV DGDGNFCDSE FHLRPPSDPE 
       490        500        510        520        530        540 
TVYKGQQDQI DQDYLMALSL QQEQQSQEIN WEQIPEGISD LELAKKLQEE EDRRASQYYQ 
       550        560        570        580        590        600 
EQEQAQAVVT TTTPSTQAQQ GQPAQASPSS IKQPGNSERK RKEPREKDKE KEKEKNSCVI 
   
L         10         20         30         40         50         60 
MENSPDSPQP LELGVAAGRV SPPEGRRRGG REAEDGPAGR AVDSGGQGAA AAAARSSLGD 
        70         80         90        100        110        120 
PTSPSQLGCG AGSDLKDGAS SSPAASEVPS RGQHKVTASP ELAEAAAGRG SGPVGDTGTC 
       130        140        150        160        170        180 
RVEQAAEEPS STGAPSSSCS EPSPPGDSPS LDSLESFSNL HSFPSSSEFN SEEGAETRVP 
       190        200        210        220        230        240 
EDVEEGAAGP PRAAPLCKEE EEDPAQVLAA SKERFPGQSV YHIKWIQWKE ENTPIITQNE 
       250        260        270        280        290        300 
NGPCPLLAIL NVLLLAWKVK LPPMMEIITA EQLMEYLGDY MLEAKPKEIS EIQRVNYEQN 
       310        320        330        340        350        360 
MSDAMAILHK LQTGLDVNVR FTGVRVFEYT PECIVFDLLD IPLYHGWLVD PQIDDIVKAV 
       370        380        390        400        410        420 
GNCSYNQLVE KIISCKQSDN SQLVSEGFVA EQFLNNTATQ LTYHGLCELT STVQEGELCV 
       430        440        450        460        470        480 
FFRNNHFSTM TKYKGQLYLL VTDQGFLTEE KIVWESLHNV DGDGNFCDSE FHLRPPSDPE 
       490        500        510        520        530        540 
TVYKGQQDQI DQDYLMALSL QQEQQSQEIN WEQIPEGISD LELAKKLQEE EDRRASQYYQ 
       550        560        570        580        590        600 
EQEQAQAVVT TTTPSTQAQQ GQPAQASPSS IKQPGNSERK RKEPREKDKE KEKEKNSCVI 
   
L



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Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6PDI6-1-unknown MENSPD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6PDI6-1-unknown MENSPD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74648
    Q6PDI6-264-unknown MMEIIT... 264 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74647
    Q6PDI6-264-unknown MMEIIT... 264 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt104408

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SCVIL 601 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SCVIL 601 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt70265

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)