TopFIND 4.0

Q6R6M4: Ubiquitin carboxyl-terminal hydrolase 17

General Information

Protein names
- Ubiquitin carboxyl-terminal hydrolase 17
- USP17
- 3.4.19.12 {ECO:0000269|PubMed:14699124, ECO:0000269|PubMed:20228808, ECO:0000269|PubMed:20368735}
- Deubiquitinating enzyme 17-like protein 2
- Deubiquitinating protein 3
- DUB-3
- Ubiquitin carboxyl-terminal hydrolase 17-like protein 2
- Ubiquitin thioesterase 17-like protein 2
- Ubiquitin-specific-processing protease 17-like protein 2
Gene names USP17L2
Organism Homo sapiens
Protease Family
Protease ID C19.023
Chromosome location
UniProt ID Q6R6M4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEDDSLYLGG EWQFNHFSKL TSSRPDAAFA EIQRTSLPEK SPLSSEARVD LCDDLAPVAR 
        70         80         90        100        110        120 
QLAPRKKLPL SSRRPAAVGA GLQNMGNTCY ENASLQCLTY TPPLANYMLS REHSQTCQRP 
       130        140        150        160        170        180 
KCCMLCTMQA HITWALHSPG HVIQPSQALA AGFHRGKQED AHEFLMFTVD AMKKACLPGH 
       190        200        210        220        230        240 
KQVDHHSKDT TLIHQIFGGC WRSQIKCLHC HGISDTFDPY LDIALDIQAA QSVKQALEQL 
       250        260        270        280        290        300 
VKPEELNGEN AYHCGLCLQR APASKTLTLH TSAKVLILVL KRFSDVTGNK LAKNVQYPEC 
       310        320        330        340        350        360 
LDMQPYMSQQ NTGPLVYVLY AVLVHAGWSC HDGHYFSYVK AQEGQWYKMD DAKVTACSIT 
       370        380        390        400        410        420 
SVLSQQAYVL FYIQKSEWER HSESVSRGRE PRALGAEDTD RRATQGELKR DHPCLQAPEL 
       430        440        450        460        470        480 
DERLVERATQ ESTLDHWKFP QEQNKTKPEF NVRKVEGTLP PNVLVIHQSK YKCGMKNHHP 
       490        500        510        520        530    
EQQSSLLNLS STTRTDQESV NTGTLASLQG RTRRSKGKNK HSKRALLVCQ 

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6R6M4-1-unknown MEDDSL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLVCQ 530 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)