Q6V0I7: Protocadherin Fat 4
| Protein names | - Protocadherin Fat 4 - hFat4 - Cadherin family member 14 - FAT tumor suppressor homolog 4 - Fat-like cadherin protein FAT-J |
|---|---|
| Gene names | FAT4 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q6V0I7 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDLAPDRATG RPWLPLHTLS VSQLLRVFWL LSLLPGQAWV HGAEPRQVFQ VLEEQPPGTL
70 80 90 100 110 120
VGTIQTRPGF TYRLSESHAL FAINSSTGAL YTTSTIDRES LPSDVINLVV LSSAPTYPTE
130 140 150 160 170 180
VRVLVRDLND NAPVFPDPSI VVTFKEDSSS GRQVILDTAT DSDIGSNGVD HRSYRIIRGN
190 200 210 220 230 240
EAGRFRLDIT LNPSGEGAFL HLVSKGGLDR EVTPQYQLLV EVEDKGEPKR RGYLQVNVTV
250 260 270 280 290 300
QDINDNPPVF GSSHYQAGVP EDAVVGSSVL QVAAADADEG TNADIRYRLQ DEGTPFQMDP
310 320 330 340 350 360
ETGLITVREP LDFEARRQYS LTVQAMDRGV PSLTGRAEAL IQLLDVNDND PVVKFRYFPA
370 380 390 400 410 420
TSRYASVDEN AQVGTVVALL TVTDADSPAA NGNISVQILG GNEQRHFEVQ SSKVPNLSLI
430 440 450 460 470 480
KVASALDRER IPSYNLTVSV SDNYGAPPGA AVQARSSVAS LVIFVNDIND HPPVFSQQVY
490 500 510 520 530 540
RVNLSEEAPP GSYVSGISAT DGDSGLNANL RYSIVSGNGL GWFHISEHSG LVTTGSSGGL
550 560 570 580 590 600
DRELASQIVL NISARDQGVH PKVSYAQLVV TLLDVNDEKP VFSQPEGYDV SVVENAPTGT
610 620 630 640 650 660
ELLMLRATDG DLGDNGTVRF SLQEAETDRR SFRLDPVSGR LSTISSLDRE EQAFYSLLVL
670 680 690 700 710 720
ATDLGSPPQS SMARINVSLL DINDNSPVFY PVQYFAHIKE NEPGGSYITT VSATDPDLGT
730 740 750 760 770 780
NGTVKYSISA GDRSRFQVNA QSGVISTRMA LDREEKTAYQ LQIVATDGGN LQSPNQAIVT
790 800 810 820 830 840
ITVLDTQDNP PVFSQVAYSF VVFENVALGY HVGSVSASTM DLNSNISYLI TTGDQKGMFA
850 860 870 880 890 900
INQVTGQLTT ANVIDREEQS FYQLKVVASG GTVTGDTMVN ITVKDLNDNS PHFLQAIESV
910 920 930 940 950 960
NVVENWQAGH SIFQAKAVDP DEGVNGMVLY SLKQNPKNLF AINEKNGTIS LLGPLDVHAG
970 980 990 1000 1010 1020
SYQIEILASD MGVPQLSSSV ILTVYVHDVN DNSPVFDQLS YEVTLSESEP VNSRFFKVQA
1030 1040 1050 1060 1070 1080
SDKDSGANGE IAYTIAEGNT GDAFGIFPDG QLYIKSELDR ELQDRYVLMV VASDRAVEPL
1090 1100 1110 1120 1130 1140
SATVNVTVIL EDVNDNRPLF NSTNYTFYFE EEQRAGSFVG KVSAVDKDFG PNGEVRYSFE
1150 1160 1170 1180 1190 1200
MVQPDFELHA ISGEITNTHQ FDRESLMRRR GTAVFSFTVI ATDQGIPQPL KDQATVHVYM
1210 1220 1230 1240 1250 1260
KDINDNAPKF LKDFYQATIS ESAANLTQVL RVSASDVDEG NNGLIHYSII KGNEERQFAI
1270 1280 1290 1300 1310 1320
DSTSGQVTLI GKLDYEATPA YSLVIQAVDS GTIPLNSTCT LNIDILDEND NTPSFPKSTL
1330 1340 1350 1360 1370 1380
FVDVLENMRI GELVSSVTAT DSDSGDNADL YYSITGTNNH GTFSISPNTG SIFLAKKLDF
1390 1400 1410 1420 1430 1440
ETQSLYKLNI TAKDQGRPPR SSTMSVVIHV RDFNDNPPSF PPGDIFKSIV ENIPIGTSVI
1450 1460 1470 1480 1490 1500
SVTAHDPDAD INGQLSYTII QQMPRGNHFT IDEVKGTIYT NAEIDREFAN LFELTVKAND
1510 1520 1530 1540 1550 1560
QAVPIETRRY ALKNVTILVT DLNDNVPMFI SQNALAADPS AVIGSVLTTI MAADPDEGAN
1570 1580 1590 1600 1610 1620
GEIEYEIING DTDTFIVDRY SGDLRVASAL VPSQLIYNLI VSATDLGPER RKSTTELTII
1630 1640 1650 1660 1670 1680
LQGLDGPVFT QPKYITILKE GEPIGTNVIS IEAASPRGSE APVEYYIVSV RCEEKTVGRL
1690 1700 1710 1720 1730 1740
FTIGRHTGII QTAAILDREQ GACLYLVDVY AIEKSTAFPR TQRAEVEITL QDINDNPPVF
1750 1760 1770 1780 1790 1800
PTDMLDLTVE ENIGDGSKIM QLTAMDADEG ANALVTYTII SGADDSFRID PESGDLIATR
1810 1820 1830 1840 1850 1860
RLDRERRSKY SLLVRADDGL QSSDMRINIT VSDVNDHTPK FSRPVYSFDI PEDTIPGSLV
1870 1880 1890 1900 1910 1920
AAILATDDDS GVNGEITYIV NEDDEDGIFF LNPITGVFNL TRLLDYEVQQ YYILTVRAED
1930 1940 1950 1960 1970 1980
GGGQFTTIRV YFNILDVNDN PPIFSLNSYS TSLMENLPVG STVLVFNVTD ADDGINSQLT
1990 2000 2010 2020 2030 2040
YSIASGDSLG QFTVDKNGVL KVLKALDRES QSFYNLVVQV HDLPQIPASR FTSTAQVSII
2050 2060 2070 2080 2090 2100
LLDVNDNPPT FLSPKLTYIP ENTPIDTVVF KAQATDPDSG PNSYIEYTLL NPLGNKFSIG
2110 2120 2130 2140 2150 2160
TIDGEVRLTG ELDREEVSNY TLTVVATDKG QPSLSSSTEV VVMVLDINDN NPIFAQALYK
2170 2180 2190 2200 2210 2220
VEINENTLTG TDIIQVFAAD GDEGTNGQVR YGIVNGNTNQ EFRIDSVTGA ITVAKPLDRE
2230 2240 2250 2260 2270 2280
KTPTYHLTVQ ATDRGSTPRT DTSTVSIVLL DINDFVPVFE LSPYSVNVPE NLGTLPRTIL
2290 2300 2310 2320 2330 2340
QVVARDDDRG SNSKLSYVLF GGNEDNAFTL SASGELGVTQ SLDRETKERF VLMITATDSG
2350 2360 2370 2380 2390 2400
SPALTGTGTI NVIVDDVNDN VPTFASKAYF TTIPEDAPTG TDVLLVNASD ADASKNAVIR
2410 2420 2430 2440 2450 2460
IIGGNSQFTI NPSTGQIITS ALLDRETKDN YTLVVVCSDA GSPEPLSSST SVLVTVTDVN
2470 2480 2490 2500 2510 2520
DNPPRFQHHP YVTHIPSPTL PGSFVFAVTV TDADIGPNSE LHYSLSGRNS EKFHIDPLRG
2530 2540 2550 2560 2570 2580
AIMAAGPLNG ASEVTFSVHV KDGGSFPKTD STTVTVRFVN KADFPKVRAK EQTFMFPENQ
2590 2600 2610 2620 2630 2640
PVSSLVTTIT GSSLRGEPMS YYIASGNLGN TFQIDQLTGQ VSISQPLDFE KIQKYVVWIE
2650 2660 2670 2680 2690 2700
ARDGGFPPFS SYEKLDITVL DVNDNAPIFK EDPFISEILE NLSPRKILTV SAMDKDSGPN
2710 2720 2730 2740 2750 2760
GQLDYEIVNG NMENSFSINH ATGEIRSVRP LDREKVSHYV LTIKSSDKGS PSQSTSVKVM
2770 2780 2790 2800 2810 2820
INILDENDNA PRFSQIFSAH VPENSPLGYT VTRVTTSDED IGINAISRYS IMDASLPFTI
2830 2840 2850 2860 2870 2880
NPSTGDIVIS RPLNREDTDR YRIRVSAHDS GWTVSTDVTI FVTDINDNAP RFSRTSYYLD
2890 2900 2910 2920 2930 2940
CPELTEIGSK VTQVFATDPD EGSNGQVFYF IKSQSEYFRI NATTGEIFNK QILKYQNVTG
2950 2960 2970 2980 2990 3000
FSNVNINRHS FIVTSSDRGK PSLISETTVT INIVDSNDNA PQFLKSKYFT PVTKNVKVGT
3010 3020 3030 3040 3050 3060
KLIRVTAIDD KDFGLNSEVE YFISNDNHLG KFKLDNDTGW ISVASSLISD LNQNFFITVT
3070 3080 3090 3100 3110 3120
AKDKGNPPLS SQATVHITVT EENYHTPEFS QSHMSATIPE SHSIGSIVRT VSARDRDAAM
3130 3140 3150 3160 3170 3180
NGLIKYSISS GNEEGIFAIN SSTGILTLAK ALDYELCQKH EMTISAIDGG WVARTGYCSV
3190 3200 3210 3220 3230 3240
TVNVIDVNDN SPVFLSDDYF PTVLENAPSG TTVIHLNATD ADSGTNAVIA YTVQSSDSDL
3250 3260 3270 3280 3290 3300
FVIDPNTGVI TTQGFLDFET KQSYHLTVKA FNVPDEERCS FATVNIQLKG TNEYVPRFVS
3310 3320 3330 3340 3350 3360
KLYYFEISEA APKGTIVGEV FASDRDLGTD GEVHYLIFGN SRKKGFQINK KTGQIYVSGI
3370 3380 3390 3400 3410 3420
LDREKEERVS LKVLAKNFGS IRGADIDEVT VNVTVLDAND PPIFTLNIYS VQISEGVPIG
3430 3440 3450 3460 3470 3480
THVTFVSAFD SDSIPSWSRF SYFIGSGNEN GAFSINPQTG QITVTAELDR ETLPIYNLSV
3490 3500 3510 3520 3530 3540
LAVDSGTPSA TGSASLLVTL EDINDNGPML TVSEGEVMEN KRPGTLVMTL QSTDPDLPPN
3550 3560 3570 3580 3590 3600
QGPFTYYLLS TGPATSYFSL STAGVLSTTR EIDREQIADF YLSVVTKDSG VPQMSSTGTV
3610 3620 3630 3640 3650 3660
HITVIDQNDN PSQSRTVEIF VNYYGNLFPG GILGSVKPQD PDVLDSFHCS LTSGVTSLFS
3670 3680 3690 3700 3710 3720
IPGGTCDLNS QPRSTDGTFD LTVLSNDGVH STVTSNIRVF FAGFSNATVD NSILLRLGVP
3730 3740 3750 3760 3770 3780
TVKDFLTNHY LHFLRIASSQ LTGLGTAVQL YSAYEENNRT FLLAAVKRNH NQYVNPSGVA
3790 3800 3810 3820 3830 3840
TFFESIKEIL LRQSGVKVES VDHDSCVHGP CQNGGSCLRR LAVSSVLKSR ESLPVIIVAN
3850 3860 3870 3880 3890 3900
EPLQPFLCKC LPGYAGSWCE IDIDECLPSP CHSGGTCHNL VGGFSCSCPD GFTGRACERD
3910 3920 3930 3940 3950 3960
INECLQSPCK NGAICQNFPG SFNCVCKTGY TGKMCESSVN YCECNPCFNG GSCQSGVDSY
3970 3980 3990 4000 4010 4020
YCHCPFGVFG KHCELNSYGF EELSYMEFPS LDPNNNYIYV KFATIKSHAL LLYNYDNQTG
4030 4040 4050 4060 4070 4080
DRAEFLALEI AEERLRFSYN LGSGTYKLTT MKKVSDGHFH TVIARRAGMA ASLTVDSCSE
4090 4100 4110 4120 4130 4140
NQEPGYCTVS NVAVSDDWTL DVQPNRVTVG GIRSLEPILQ RRGHVESHDF VGCIMEFAVN
4150 4160 4170 4180 4190 4200
GRPLEPSQAL AAQGILDQCP RLEGACTRSP CQHGGTCMDY WSWQQCHCKE GLTGKYCEKS
4210 4220 4230 4240 4250 4260
VTPDTALSLE GKGRLDYHMS QNEKREYLLR QSLRGAMLEP FGVNSLEVKF RTRSENGVLI
4270 4280 4290 4300 4310 4320
HIQESSNYTT VKIKNGKVYF TSDAGIAGKV ERNIPEVYVA DGHWHTFLIG KNGTATVLSV
4330 4340 4350 4360 4370 4380
DRIYNRDIIH PTQDFGGLDV LTISLGGIPP NQAHRDAQTA GFDGCIASMW YGGESLPFSG
4390 4400 4410 4420 4430 4440
KHSLASISKT DPSVKIGCRG PNICASNPCW GDLLCINQWY AYRCVPPGDC ASHPCQNGGS
4450 4460 4470 4480 4490 4500
CEPGLHSGFT CSCPDSHTGR TCEMVVACLG VLCPQGKVCK AGSPAGHVCV LSQGPEEISL
4510 4520 4530 4540 4550 4560
PLWAVPAIVG SCATVLALLV LSLILCNQCR GKKAKNPKEE KKPKEKKKKG SENVAFDDPD
4570 4580 4590 4600 4610 4620
NIPPYGDDMT VRKQPEGNPK PDIIERENPY LIYDETDIPH NSETIPSAPL ASPEQEIEHY
4630 4640 4650 4660 4670 4680
DIDNASSIAP SDADIIQHYK QFRSHTPKFS IQRHSPLGFA RQSPMPLGAS SLTYQPSYGQ
4690 4700 4710 4720 4730 4740
GLRTSSLSHS ACPTPNPLSR HSPAPFSKSS TFYRNSPARE LHLPIRDGNT LEMHGDTCQP
4750 4760 4770 4780 4790 4800
GIFNYATRLG RRSKSPQAMA SHGSRPGSRL KQPIGQIPLE SSPPVGLSIE EVERLNTPRP
4810 4820 4830 4840 4850 4860
RNPSICSADH GRSSSEEDCR RPLSRTRNPA DGIPAPESSS DSDSHESFTC SEMEYDREKP
4870 4880 4890 4900 4910 4920
MVYTSRMPKL SQVNESDADD EDNYGARLKP RRYHGRRAEG GPVGTQAAAP GTADNTLPMK
4930 4940 4950 4960 4970 4980
LGQQAGTFNW DNLLNWGPGF GHYVDVFKDL ASLPEKAAAN EEGKAGTTKP VPKDGEAEQY
V
Isoforms
- Isoform 2 of Protocadherin Fat 4 - Isoform 3 of Protocadherin Fat 4Sequence View
10 20 30 40 50 60
MDLAPDRATG RPWLPLHTLS VSQLLRVFWL LSLLPGQAWV HGAEPRQVFQ VLEEQPPGTL
70 80 90 100 110 120
VGTIQTRPGF TYRLSESHAL FAINSSTGAL YTTSTIDRES LPSDVINLVV LSSAPTYPTE
130 140 150 160 170 180
VRVLVRDLND NAPVFPDPSI VVTFKEDSSS GRQVILDTAT DSDIGSNGVD HRSYRIIRGN
190 200 210 220 230 240
EAGRFRLDIT LNPSGEGAFL HLVSKGGLDR EVTPQYQLLV EVEDKGEPKR RGYLQVNVTV
250 260 270 280 290 300
QDINDNPPVF GSSHYQAGVP EDAVVGSSVL QVAAADADEG TNADIRYRLQ DEGTPFQMDP
310 320 330 340 350 360
ETGLITVREP LDFEARRQYS LTVQAMDRGV PSLTGRAEAL IQLLDVNDND PVVKFRYFPA
370 380 390 400 410 420
TSRYASVDEN AQVGTVVALL TVTDADSPAA NGNISVQILG GNEQRHFEVQ SSKVPNLSLI
430 440 450 460 470 480
KVASALDRER IPSYNLTVSV SDNYGAPPGA AVQARSSVAS LVIFVNDIND HPPVFSQQVY
490 500 510 520 530 540
RVNLSEEAPP GSYVSGISAT DGDSGLNANL RYSIVSGNGL GWFHISEHSG LVTTGSSGGL
550 560 570 580 590 600
DRELASQIVL NISARDQGVH PKVSYAQLVV TLLDVNDEKP VFSQPEGYDV SVVENAPTGT
610 620 630 640 650 660
ELLMLRATDG DLGDNGTVRF SLQEAETDRR SFRLDPVSGR LSTISSLDRE EQAFYSLLVL
670 680 690 700 710 720
ATDLGSPPQS SMARINVSLL DINDNSPVFY PVQYFAHIKE NEPGGSYITT VSATDPDLGT
730 740 750 760 770 780
NGTVKYSISA GDRSRFQVNA QSGVISTRMA LDREEKTAYQ LQIVATDGGN LQSPNQAIVT
790 800 810 820 830 840
ITVLDTQDNP PVFSQVAYSF VVFENVALGY HVGSVSASTM DLNSNISYLI TTGDQKGMFA
850 860 870 880 890 900
INQVTGQLTT ANVIDREEQS FYQLKVVASG GTVTGDTMVN ITVKDLNDNS PHFLQAIESV
910 920 930 940 950 960
NVVENWQAGH SIFQAKAVDP DEGVNGMVLY SLKQNPKNLF AINEKNGTIS LLGPLDVHAG
970 980 990 1000 1010 1020
SYQIEILASD MGVPQLSSSV ILTVYVHDVN DNSPVFDQLS YEVTLSESEP VNSRFFKVQA
1030 1040 1050 1060 1070 1080
SDKDSGANGE IAYTIAEGNT GDAFGIFPDG QLYIKSELDR ELQDRYVLMV VASDRAVEPL
1090 1100 1110 1120 1130 1140
SATVNVTVIL EDVNDNRPLF NSTNYTFYFE EEQRAGSFVG KVSAVDKDFG PNGEVRYSFE
1150 1160 1170 1180 1190 1200
MVQPDFELHA ISGEITNTHQ FDRESLMRRR GTAVFSFTVI ATDQGIPQPL KDQATVHVYM
1210 1220 1230 1240 1250 1260
KDINDNAPKF LKDFYQATIS ESAANLTQVL RVSASDVDEG NNGLIHYSII KGNEERQFAI
1270 1280 1290 1300 1310 1320
DSTSGQVTLI GKLDYEATPA YSLVIQAVDS GTIPLNSTCT LNIDILDEND NTPSFPKSTL
1330 1340 1350 1360 1370 1380
FVDVLENMRI GELVSSVTAT DSDSGDNADL YYSITGTNNH GTFSISPNTG SIFLAKKLDF
1390 1400 1410 1420 1430 1440
ETQSLYKLNI TAKDQGRPPR SSTMSVVIHV RDFNDNPPSF PPGDIFKSIV ENIPIGTSVI
1450 1460 1470 1480 1490 1500
SVTAHDPDAD INGQLSYTII QQMPRGNHFT IDEVKGTIYT NAEIDREFAN LFELTVKAND
1510 1520 1530 1540 1550 1560
QAVPIETRRY ALKNVTILVT DLNDNVPMFI SQNALAADPS AVIGSVLTTI MAADPDEGAN
1570 1580 1590 1600 1610 1620
GEIEYEIING DTDTFIVDRY SGDLRVASAL VPSQLIYNLI VSATDLGPER RKSTTELTII
1630 1640 1650 1660 1670 1680
LQGLDGPVFT QPKYITILKE GEPIGTNVIS IEAASPRGSE APVEYYIVSV RCEEKTVGRL
1690 1700 1710 1720 1730 1740
FTIGRHTGII QTAAILDREQ GACLYLVDVY AIEKSTAFPR TQRAEVEITL QDINDNPPVF
1750 1760 1770 1780 1790 1800
PTDMLDLTVE ENIGDGSKIM QLTAMDADEG ANALVTYTII SGADDSFRID PESGDLIATR
1810 1820 1830 1840 1850 1860
RLDRERRSKY SLLVRADDGL QSSDMRINIT VSDVNDHTPK FSRPVYSFDI PEDTIPGSLV
1870 1880 1890 1900 1910 1920
AAILATDDDS GVNGEITYIV NEDDEDGIFF LNPITGVFNL TRLLDYEVQQ YYILTVRAED
1930 1940 1950 1960 1970 1980
GGGQFTTIRV YFNILDVNDN PPIFSLNSYS TSLMENLPVG STVLVFNVTD ADDGINSQLT
1990 2000 2010 2020 2030 2040
YSIASGDSLG QFTVDKNGVL KVLKALDRES QSFYNLVVQV HDLPQIPASR FTSTAQVSII
2050 2060 2070 2080 2090 2100
LLDVNDNPPT FLSPKLTYIP ENTPIDTVVF KAQATDPDSG PNSYIEYTLL NPLGNKFSIG
2110 2120 2130 2140 2150 2160
TIDGEVRLTG ELDREEVSNY TLTVVATDKG QPSLSSSTEV VVMVLDINDN NPIFAQALYK
2170 2180 2190 2200 2210 2220
VEINENTLTG TDIIQVFAAD GDEGTNGQVR YGIVNGNTNQ EFRIDSVTGA ITVAKPLDRE
2230 2240 2250 2260 2270 2280
KTPTYHLTVQ ATDRGSTPRT DTSTVSIVLL DINDFVPVFE LSPYSVNVPE NLGTLPRTIL
2290 2300 2310 2320 2330 2340
QVVARDDDRG SNSKLSYVLF GGNEDNAFTL SASGELGVTQ SLDRETKERF VLMITATDSG
2350 2360 2370 2380 2390 2400
SPALTGTGTI NVIVDDVNDN VPTFASKAYF TTIPEDAPTG TDVLLVNASD ADASKNAVIR
2410 2420 2430 2440 2450 2460
IIGGNSQFTI NPSTGQIITS ALLDRETKDN YTLVVVCSDA GSPEPLSSST SVLVTVTDVN
2470 2480 2490 2500 2510 2520
DNPPRFQHHP YVTHIPSPTL PGSFVFAVTV TDADIGPNSE LHYSLSGRNS EKFHIDPLRG
2530 2540 2550 2560 2570 2580
AIMAAGPLNG ASEVTFSVHV KDGGSFPKTD STTVTVRFVN KADFPKVRAK EQTFMFPENQ
2590 2600 2610 2620 2630 2640
PVSSLVTTIT GSSLRGEPMS YYIASGNLGN TFQIDQLTGQ VSISQPLDFE KIQKYVVWIE
2650 2660 2670 2680 2690 2700
ARDGGFPPFS SYEKLDITVL DVNDNAPIFK EDPFISEILE NLSPRKILTV SAMDKDSGPN
2710 2720 2730 2740 2750 2760
GQLDYEIVNG NMENSFSINH ATGEIRSVRP LDREKVSHYV LTIKSSDKGS PSQSTSVKVM
2770 2780 2790 2800 2810 2820
INILDENDNA PRFSQIFSAH VPENSPLGYT VTRVTTSDED IGINAISRYS IMDASLPFTI
2830 2840 2850 2860 2870 2880
NPSTGDIVIS RPLNREDTDR YRIRVSAHDS GWTVSTDVTI FVTDINDNAP RFSRTSYYLD
2890 2900 2910 2920 2930 2940
CPELTEIGSK VTQVFATDPD EGSNGQVFYF IKSQSEYFRI NATTGEIFNK QILKYQNVTG
2950 2960 2970 2980 2990 3000
FSNVNINRHS FIVTSSDRGK PSLISETTVT INIVDSNDNA PQFLKSKYFT PVTKNVKVGT
3010 3020 3030 3040 3050 3060
KLIRVTAIDD KDFGLNSEVE YFISNDNHLG KFKLDNDTGW ISVASSLISD LNQNFFITVT
3070 3080 3090 3100 3110 3120
AKDKGNPPLS SQATVHITVT EENYHTPEFS QSHMSATIPE SHSIGSIVRT VSARDRDAAM
3130 3140 3150 3160 3170 3180
NGLIKYSISS GNEEGIFAIN SSTGILTLAK ALDYELCQKH EMTISAIDGG WVARTGYCSV
3190 3200 3210 3220 3230 3240
TVNVIDVNDN SPVFLSDDYF PTVLENAPSG TTVIHLNATD ADSGTNAVIA YTVQSSDSDL
3250 3260 3270 3280 3290 3300
FVIDPNTGVI TTQGFLDFET KQSYHLTVKA FNVPDEERCS FATVNIQLKG TNEYVPRFVS
3310 3320 3330 3340 3350 3360
KLYYFEISEA APKGTIVGEV FASDRDLGTD GEVHYLIFGN SRKKGFQINK KTGQIYVSGI
3370 3380 3390 3400 3410 3420
LDREKEERVS LKVLAKNFGS IRGADIDEVT VNVTVLDAND PPIFTLNIYS VQISEGVPIG
3430 3440 3450 3460 3470 3480
THVTFVSAFD SDSIPSWSRF SYFIGSGNEN GAFSINPQTG QITVTAELDR ETLPIYNLSV
3490 3500 3510 3520 3530 3540
LAVDSGTPSA TGSASLLVTL EDINDNGPML TVSEGEVMEN KRPGTLVMTL QSTDPDLPPN
3550 3560 3570 3580 3590 3600
QGPFTYYLLS TGPATSYFSL STAGVLSTTR EIDREQIADF YLSVVTKDSG VPQMSSTGTV
3610 3620 3630 3640 3650 3660
HITVIDQNDN PSQSRTVEIF VNYYGNLFPG GILGSVKPQD PDVLDSFHCS LTSGVTSLFS
3670 3680 3690 3700 3710 3720
IPGGTCDLNS QPRSTDGTFD LTVLSNDGVH STVTSNIRVF FAGFSNATVD NSILLRLGVP
3730 3740 3750 3760 3770 3780
TVKDFLTNHY LHFLRIASSQ LTGLGTAVQL YSAYEENNRT FLLAAVKRNH NQYVNPSGVA
3790 3800 3810 3820 3830 3840
TFFESIKEIL LRQSGVKVES VDHDSCVHGP CQNGGSCLRR LAVSSVLKSR ESLPVIIVAN
3850 3860 3870 3880 3890 3900
EPLQPFLCKC LPGYAGSWCE IDIDECLPSP CHSGGTCHNL VGGFSCSCPD GFTGRACERD
3910 3920 3930 3940 3950 3960
INECLQSPCK NGAICQNFPG SFNCVCKTGY TGKMCESSVN YCECNPCFNG GSCQSGVDSY
3970 3980 3990 4000 4010 4020
YCHCPFGVFG KHCELNSYGF EELSYMEFPS LDPNNNYIYV KFATIKSHAL LLYNYDNQTG
4030 4040 4050 4060 4070 4080
DRAEFLALEI AEERLRFSYN LGSGTYKLTT MKKVSDGHFH TVIARRAGMA ASLTVDSCSE
4090 4100 4110 4120 4130 4140
NQEPGYCTVS NVAVSDDWTL DVQPNRVTVG GIRSLEPILQ RRGHVESHDF VGCIMEFAVN
4150 4160 4170 4180 4190 4200
GRPLEPSQAL AAQGILDQCP RLEGACTRSP CQHGGTCMDY WSWQQCHCKE GLTGKYCEKS
4210 4220 4230 4240 4250 4260
VTPDTALSLE GKGRLDYHMS QNEKREYLLR QSLRGAMLEP FGVNSLEVKF RTRSENGVLI
4270 4280 4290 4300 4310 4320
HIQESSNYTT VKIKNGKVYF TSDAGIAGKV ERNIPEVYVA DGHWHTFLIG KNGTATVLSV
4330 4340 4350 4360 4370 4380
DRIYNRDIIH PTQDFGGLDV LTISLGGIPP NQAHRDAQTA GFDGCIASMW YGGESLPFSG
4390 4400 4410 4420 4430 4440
KHSLASISKT DPSVKIGCRG PNICASNPCW GDLLCINQWY AYRCVPPGDC ASHPCQNGGS
4450 4460 4470 4480 4490 4500
CEPGLHSGFT CSCPDSHTGR TCEMVVACLG VLCPQGKVCK AGSPAGHVCV LSQGPEEISL
4510 4520 4530 4540 4550 4560
PLWAVPAIVG SCATVLALLV LSLILCNQCR GKKAKNPKEE KKPKEKKKKG SENVAFDDPD
4570 4580 4590 4600 4610 4620
NIPPYGDDMT VRKQPEGNPK PDIIERENPY LIYDETDIPH NSETIPSAPL ASPEQEIEHY
4630 4640 4650 4660 4670 4680
DIDNASSIAP SDADIIQHYK QFRSHTPKFS IQRHSPLGFA RQSPMPLGAS SLTYQPSYGQ
4690 4700 4710 4720 4730 4740
GLRTSSLSHS ACPTPNPLSR HSPAPFSKSS TFYRNSPARE LHLPIRDGNT LEMHGDTCQP
4750 4760 4770 4780 4790 4800
GIFNYATRLG RRSKSPQAMA SHGSRPGSRL KQPIGQIPLE SSPPVGLSIE EVERLNTPRP
4810 4820 4830 4840 4850 4860
RNPSICSADH GRSSSEEDCR RPLSRTRNPA DGIPAPESSS DSDSHESFTC SEMEYDREKP
4870 4880 4890 4900 4910 4920
MVYTSRMPKL SQVNESDADD EDNYGARLKP RRYHGRRAEG GPVGTQAAAP GTADNTLPMK
4930 4940 4950 4960 4970 4980
LGQQAGTFNW DNLLNWGPGF GHYVDVFKDL ASLPEKAAAN EEGKAGTTKP VPKDGEAEQY
V
10 20 30 40 50 60
MDLAPDRATG RPWLPLHTLS VSQLLRVFWL LSLLPGQAWV HGAEPRQVFQ VLEEQPPGTL
70 80 90 100 110 120
VGTIQTRPGF TYRLSESHAL FAINSSTGAL YTTSTIDRES LPSDVINLVV LSSAPTYPTE
130 140 150 160 170 180
VRVLVRDLND NAPVFPDPSI VVTFKEDSSS GRQVILDTAT DSDIGSNGVD HRSYRIIRGN
190 200 210 220 230 240
EAGRFRLDIT LNPSGEGAFL HLVSKGGLDR EVTPQYQLLV EVEDKGEPKR RGYLQVNVTV
250 260 270 280 290 300
QDINDNPPVF GSSHYQAGVP EDAVVGSSVL QVAAADADEG TNADIRYRLQ DEGTPFQMDP
310 320 330 340 350 360
ETGLITVREP LDFEARRQYS LTVQAMDRGV PSLTGRAEAL IQLLDVNDND PVVKFRYFPA
370 380 390 400 410 420
TSRYASVDEN AQVGTVVALL TVTDADSPAA NGNISVQILG GNEQRHFEVQ SSKVPNLSLI
430 440 450 460 470 480
KVASALDRER IPSYNLTVSV SDNYGAPPGA AVQARSSVAS LVIFVNDIND HPPVFSQQVY
490 500 510 520 530 540
RVNLSEEAPP GSYVSGISAT DGDSGLNANL RYSIVSGNGL GWFHISEHSG LVTTGSSGGL
550 560 570 580 590 600
DRELASQIVL NISARDQGVH PKVSYAQLVV TLLDVNDEKP VFSQPEGYDV SVVENAPTGT
610 620 630 640 650 660
ELLMLRATDG DLGDNGTVRF SLQEAETDRR SFRLDPVSGR LSTISSLDRE EQAFYSLLVL
670 680 690 700 710 720
ATDLGSPPQS SMARINVSLL DINDNSPVFY PVQYFAHIKE NEPGGSYITT VSATDPDLGT
730 740 750 760 770 780
NGTVKYSISA GDRSRFQVNA QSGVISTRMA LDREEKTAYQ LQIVATDGGN LQSPNQAIVT
790 800 810 820 830 840
ITVLDTQDNP PVFSQVAYSF VVFENVALGY HVGSVSASTM DLNSNISYLI TTGDQKGMFA
850 860 870 880 890 900
INQVTGQLTT ANVIDREEQS FYQLKVVASG GTVTGDTMVN ITVKDLNDNS PHFLQAIESV
910 920 930 940 950 960
NVVENWQAGH SIFQAKAVDP DEGVNGMVLY SLKQNPKNLF AINEKNGTIS LLGPLDVHAG
970 980 990 1000 1010 1020
SYQIEILASD MGVPQLSSSV ILTVYVHDVN DNSPVFDQLS YEVTLSESEP VNSRFFKVQA
1030 1040 1050 1060 1070 1080
SDKDSGANGE IAYTIAEGNT GDAFGIFPDG QLYIKSELDR ELQDRYVLMV VASDRAVEPL
1090 1100 1110 1120 1130 1140
SATVNVTVIL EDVNDNRPLF NSTNYTFYFE EEQRAGSFVG KVSAVDKDFG PNGEVRYSFE
1150 1160 1170 1180 1190 1200
MVQPDFELHA ISGEITNTHQ FDRESLMRRR GTAVFSFTVI ATDQGIPQPL KDQATVHVYM
1210 1220 1230 1240 1250 1260
KDINDNAPKF LKDFYQATIS ESAANLTQVL RVSASDVDEG NNGLIHYSII KGNEERQFAI
1270 1280 1290 1300 1310 1320
DSTSGQVTLI GKLDYEATPA YSLVIQAVDS GTIPLNSTCT LNIDILDEND NTPSFPKSTL
1330 1340 1350 1360 1370 1380
FVDVLENMRI GELVSSVTAT DSDSGDNADL YYSITGTNNH GTFSISPNTG SIFLAKKLDF
1390 1400 1410 1420 1430 1440
ETQSLYKLNI TAKDQGRPPR SSTMSVVIHV RDFNDNPPSF PPGDIFKSIV ENIPIGTSVI
1450 1460 1470 1480 1490 1500
SVTAHDPDAD INGQLSYTII QQMPRGNHFT IDEVKGTIYT NAEIDREFAN LFELTVKAND
1510 1520 1530 1540 1550 1560
QAVPIETRRY ALKNVTILVT DLNDNVPMFI SQNALAADPS AVIGSVLTTI MAADPDEGAN
1570 1580 1590 1600 1610 1620
GEIEYEIING DTDTFIVDRY SGDLRVASAL VPSQLIYNLI VSATDLGPER RKSTTELTII
1630 1640 1650 1660 1670 1680
LQGLDGPVFT QPKYITILKE GEPIGTNVIS IEAASPRGSE APVEYYIVSV RCEEKTVGRL
1690 1700 1710 1720 1730 1740
FTIGRHTGII QTAAILDREQ GACLYLVDVY AIEKSTAFPR TQRAEVEITL QDINDNPPVF
1750 1760 1770 1780 1790 1800
PTDMLDLTVE ENIGDGSKIM QLTAMDADEG ANALVTYTII SGADDSFRID PESGDLIATR
1810 1820 1830 1840 1850 1860
RLDRERRSKY SLLVRADDGL QSSDMRINIT VSDVNDHTPK FSRPVYSFDI PEDTIPGSLV
1870 1880 1890 1900 1910 1920
AAILATDDDS GVNGEITYIV NEDDEDGIFF LNPITGVFNL TRLLDYEVQQ YYILTVRAED
1930 1940 1950 1960 1970 1980
GGGQFTTIRV YFNILDVNDN PPIFSLNSYS TSLMENLPVG STVLVFNVTD ADDGINSQLT
1990 2000 2010 2020 2030 2040
YSIASGDSLG QFTVDKNGVL KVLKALDRES QSFYNLVVQV HDLPQIPASR FTSTAQVSII
2050 2060 2070 2080 2090 2100
LLDVNDNPPT FLSPKLTYIP ENTPIDTVVF KAQATDPDSG PNSYIEYTLL NPLGNKFSIG
2110 2120 2130 2140 2150 2160
TIDGEVRLTG ELDREEVSNY TLTVVATDKG QPSLSSSTEV VVMVLDINDN NPIFAQALYK
2170 2180 2190 2200 2210 2220
VEINENTLTG TDIIQVFAAD GDEGTNGQVR YGIVNGNTNQ EFRIDSVTGA ITVAKPLDRE
2230 2240 2250 2260 2270 2280
KTPTYHLTVQ ATDRGSTPRT DTSTVSIVLL DINDFVPVFE LSPYSVNVPE NLGTLPRTIL
2290 2300 2310 2320 2330 2340
QVVARDDDRG SNSKLSYVLF GGNEDNAFTL SASGELGVTQ SLDRETKERF VLMITATDSG
2350 2360 2370 2380 2390 2400
SPALTGTGTI NVIVDDVNDN VPTFASKAYF TTIPEDAPTG TDVLLVNASD ADASKNAVIR
2410 2420 2430 2440 2450 2460
IIGGNSQFTI NPSTGQIITS ALLDRETKDN YTLVVVCSDA GSPEPLSSST SVLVTVTDVN
2470 2480 2490 2500 2510 2520
DNPPRFQHHP YVTHIPSPTL PGSFVFAVTV TDADIGPNSE LHYSLSGRNS EKFHIDPLRG
2530 2540 2550 2560 2570 2580
AIMAAGPLNG ASEVTFSVHV KDGGSFPKTD STTVTVRFVN KADFPKVRAK EQTFMFPENQ
2590 2600 2610 2620 2630 2640
PVSSLVTTIT GSSLRGEPMS YYIASGNLGN TFQIDQLTGQ VSISQPLDFE KIQKYVVWIE
2650 2660 2670 2680 2690 2700
ARDGGFPPFS SYEKLDITVL DVNDNAPIFK EDPFISEILE NLSPRKILTV SAMDKDSGPN
2710 2720 2730 2740 2750 2760
GQLDYEIVNG NMENSFSINH ATGEIRSVRP LDREKVSHYV LTIKSSDKGS PSQSTSVKVM
2770 2780 2790 2800 2810 2820
INILDENDNA PRFSQIFSAH VPENSPLGYT VTRVTTSDED IGINAISRYS IMDASLPFTI
2830 2840 2850 2860 2870 2880
NPSTGDIVIS RPLNREDTDR YRIRVSAHDS GWTVSTDVTI FVTDINDNAP RFSRTSYYLD
2890 2900 2910 2920 2930 2940
CPELTEIGSK VTQVFATDPD EGSNGQVFYF IKSQSEYFRI NATTGEIFNK QILKYQNVTG
2950 2960 2970 2980 2990 3000
FSNVNINRHS FIVTSSDRGK PSLISETTVT INIVDSNDNA PQFLKSKYFT PVTKNVKVGT
3010 3020 3030 3040 3050 3060
KLIRVTAIDD KDFGLNSEVE YFISNDNHLG KFKLDNDTGW ISVASSLISD LNQNFFITVT
3070 3080 3090 3100 3110 3120
AKDKGNPPLS SQATVHITVT EENYHTPEFS QSHMSATIPE SHSIGSIVRT VSARDRDAAM
3130 3140 3150 3160 3170 3180
NGLIKYSISS GNEEGIFAIN SSTGILTLAK ALDYELCQKH EMTISAIDGG WVARTGYCSV
3190 3200 3210 3220 3230 3240
TVNVIDVNDN SPVFLSDDYF PTVLENAPSG TTVIHLNATD ADSGTNAVIA YTVQSSDSDL
3250 3260 3270 3280 3290 3300
FVIDPNTGVI TTQGFLDFET KQSYHLTVKA FNVPDEERCS FATVNIQLKG TNEYVPRFVS
3310 3320 3330 3340 3350 3360
KLYYFEISEA APKGTIVGEV FASDRDLGTD GEVHYLIFGN SRKKGFQINK KTGQIYVSGI
3370 3380 3390 3400 3410 3420
LDREKEERVS LKVLAKNFGS IRGADIDEVT VNVTVLDAND PPIFTLNIYS VQISEGVPIG
3430 3440 3450 3460 3470 3480
THVTFVSAFD SDSIPSWSRF SYFIGSGNEN GAFSINPQTG QITVTAELDR ETLPIYNLSV
3490 3500 3510 3520 3530 3540
LAVDSGTPSA TGSASLLVTL EDINDNGPML TVSEGEVMEN KRPGTLVMTL QSTDPDLPPN
3550 3560 3570 3580 3590 3600
QGPFTYYLLS TGPATSYFSL STAGVLSTTR EIDREQIADF YLSVVTKDSG VPQMSSTGTV
3610 3620 3630 3640 3650 3660
HITVIDQNDN PSQSRTVEIF VNYYGNLFPG GILGSVKPQD PDVLDSFHCS LTSGVTSLFS
3670 3680 3690 3700 3710 3720
IPGGTCDLNS QPRSTDGTFD LTVLSNDGVH STVTSNIRVF FAGFSNATVD NSILLRLGVP
3730 3740 3750 3760 3770 3780
TVKDFLTNHY LHFLRIASSQ LTGLGTAVQL YSAYEENNRT FLLAAVKRNH NQYVNPSGVA
3790 3800 3810 3820 3830 3840
TFFESIKEIL LRQSGVKVES VDHDSCVHGP CQNGGSCLRR LAVSSVLKSR ESLPVIIVAN
3850 3860 3870 3880 3890 3900
EPLQPFLCKC LPGYAGSWCE IDIDECLPSP CHSGGTCHNL VGGFSCSCPD GFTGRACERD
3910 3920 3930 3940 3950 3960
INECLQSPCK NGAICQNFPG SFNCVCKTGY TGKMCESSVN YCECNPCFNG GSCQSGVDSY
3970 3980 3990 4000 4010 4020
YCHCPFGVFG KHCELNSYGF EELSYMEFPS LDPNNNYIYV KFATIKSHAL LLYNYDNQTG
4030 4040 4050 4060 4070 4080
DRAEFLALEI AEERLRFSYN LGSGTYKLTT MKKVSDGHFH TVIARRAGMA ASLTVDSCSE
4090 4100 4110 4120 4130 4140
NQEPGYCTVS NVAVSDDWTL DVQPNRVTVG GIRSLEPILQ RRGHVESHDF VGCIMEFAVN
4150 4160 4170 4180 4190 4200
GRPLEPSQAL AAQGILDQCP RLEGACTRSP CQHGGTCMDY WSWQQCHCKE GLTGKYCEKS
4210 4220 4230 4240 4250 4260
VTPDTALSLE GKGRLDYHMS QNEKREYLLR QSLRGAMLEP FGVNSLEVKF RTRSENGVLI
4270 4280 4290 4300 4310 4320
HIQESSNYTT VKIKNGKVYF TSDAGIAGKV ERNIPEVYVA DGHWHTFLIG KNGTATVLSV
4330 4340 4350 4360 4370 4380
DRIYNRDIIH PTQDFGGLDV LTISLGGIPP NQAHRDAQTA GFDGCIASMW YGGESLPFSG
4390 4400 4410 4420 4430 4440
KHSLASISKT DPSVKIGCRG PNICASNPCW GDLLCINQWY AYRCVPPGDC ASHPCQNGGS
4450 4460 4470 4480 4490 4500
CEPGLHSGFT CSCPDSHTGR TCEMVVACLG VLCPQGKVCK AGSPAGHVCV LSQGPEEISL
4510 4520 4530 4540 4550 4560
PLWAVPAIVG SCATVLALLV LSLILCNQCR GKKAKNPKEE KKPKEKKKKG SENVAFDDPD
4570 4580 4590 4600 4610 4620
NIPPYGDDMT VRKQPEGNPK PDIIERENPY LIYDETDIPH NSETIPSAPL ASPEQEIEHY
4630 4640 4650 4660 4670 4680
DIDNASSIAP SDADIIQHYK QFRSHTPKFS IQRHSPLGFA RQSPMPLGAS SLTYQPSYGQ
4690 4700 4710 4720 4730 4740
GLRTSSLSHS ACPTPNPLSR HSPAPFSKSS TFYRNSPARE LHLPIRDGNT LEMHGDTCQP
4750 4760 4770 4780 4790 4800
GIFNYATRLG RRSKSPQAMA SHGSRPGSRL KQPIGQIPLE SSPPVGLSIE EVERLNTPRP
4810 4820 4830 4840 4850 4860
RNPSICSADH GRSSSEEDCR RPLSRTRNPA DGIPAPESSS DSDSHESFTC SEMEYDREKP
4870 4880 4890 4900 4910 4920
MVYTSRMPKL SQVNESDADD EDNYGARLKP RRYHGRRAEG GPVGTQAAAP GTADNTLPMK
4930 4940 4950 4960 4970 4980
LGQQAGTFNW DNLLNWGPGF GHYVDVFKDL ASLPEKAAAN EEGKAGTTKP VPKDGEAEQY
V
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q6V0I7-1-unknown | MDLAPD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt74811 | |||
| Q6V0I7-39-unknown | WVHGAE... | 39 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q6V0I7-39-unknown | WVHGAE... | 39 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt115363 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...AEQYV | 4981 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...AEQYV | 4981 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt70428 | |||
| ...AEQYV | 4981 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt70429 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|