TopFIND 4.0

Q6W3F0: Prolyl 4-hydroxylase subunit alpha-3

General Information

Protein names
- Prolyl 4-hydroxylase subunit alpha-3
- 4-PH alpha-3
- 1.14.11.2
- Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3
Gene names P4ha3
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q6W3F0

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGPGARLALL ALLALGGDPA AATGREDTFS ALTSVARALA PERRLLGTLR RYLRGEEARL 
        70         80         90        100        110        120 
RDLTRFYDKV LSLHEDLKIP VVNPLLAFTV IKRLQSDWRN VVHSLEATEN IRALKDGYEK 
       130        140        150        160        170        180 
VEQDLPAFED LEGAARALMR LQDVYMLNVK GLARGVFQRV TGSSITDLYS PRQLFSLTAD 
       190        200        210        220        230        240 
DCFQVGKVAY DTGDYYHAIP WLEEAVSLFR RAHGEWKTED EASLEDALDY LAFACFQVGN 
       250        260        270        280        290        300 
VSCALSLSRE FLVYSPDNKR MARNVLKYER LLAENGHQMA AETAIQRPNV PHLQTRDTYE 
       310        320        330        340        350        360 
GLCQTLGSQP THYQIPSLYC SYETNSSPYL LLQPARKEVV HLRPLIALYH DFVSDEEAQK 
       370        380        390        400        410        420 
IRELAEPWLQ RSVVASGEKQ LQVEYRISKS AWLKDTVDPM LVTLDHRIAA LTGLDIQPPY 
       430        440        450        460        470        480 
AEYLQVVNYG IGGHYEPHFD HATSPSSPLY RMKSGNRVAT FMIYLSSVEA GGATAFIYGN 
       490        500        510        520        530        540 
FSVPVVKNAA LFWWNLHRSG EGDGDTLHAG CPVLVGDKWV ANKWIHEYGQ EFRRPCSTNP 
   
ED

Isoforms

- Isoform 2 of Prolyl 4-hydroxylase subunit alpha-3 - Isoform 3 of Prolyl 4-hydroxylase subunit alpha-3

Sequence View

        10         20         30         40         50         60 
MGPGARLALL ALLALGGDPA AATGREDTFS ALTSVARALA PERRLLGTLR RYLRGEEARL 
        70         80         90        100        110        120 
RDLTRFYDKV LSLHEDLKIP VVNPLLAFTV IKRLQSDWRN VVHSLEATEN IRALKDGYEK 
       130        140        150        160        170        180 
VEQDLPAFED LEGAARALMR LQDVYMLNVK GLARGVFQRV TGSSITDLYS PRQLFSLTAD 
       190        200        210        220        230        240 
DCFQVGKVAY DTGDYYHAIP WLEEAVSLFR RAHGEWKTED EASLEDALDY LAFACFQVGN 
       250        260        270        280        290        300 
VSCALSLSRE FLVYSPDNKR MARNVLKYER LLAENGHQMA AETAIQRPNV PHLQTRDTYE 
       310        320        330        340        350        360 
GLCQTLGSQP THYQIPSLYC SYETNSSPYL LLQPARKEVV HLRPLIALYH DFVSDEEAQK 
       370        380        390        400        410        420 
IRELAEPWLQ RSVVASGEKQ LQVEYRISKS AWLKDTVDPM LVTLDHRIAA LTGLDIQPPY 
       430        440        450        460        470        480 
AEYLQVVNYG IGGHYEPHFD HATSPSSPLY RMKSGNRVAT FMIYLSSVEA GGATAFIYGN 
       490        500        510        520        530        540 
FSVPVVKNAA LFWWNLHRSG EGDGDTLHAG CPVLVGDKWV ANKWIHEYGQ EFRRPCSTNP 
   
ED         10         20         30         40         50         60 
MGPGARLALL ALLALGGDPA AATGREDTFS ALTSVARALA PERRLLGTLR RYLRGEEARL 
        70         80         90        100        110        120 
RDLTRFYDKV LSLHEDLKIP VVNPLLAFTV IKRLQSDWRN VVHSLEATEN IRALKDGYEK 
       130        140        150        160        170        180 
VEQDLPAFED LEGAARALMR LQDVYMLNVK GLARGVFQRV TGSSITDLYS PRQLFSLTAD 
       190        200        210        220        230        240 
DCFQVGKVAY DTGDYYHAIP WLEEAVSLFR RAHGEWKTED EASLEDALDY LAFACFQVGN 
       250        260        270        280        290        300 
VSCALSLSRE FLVYSPDNKR MARNVLKYER LLAENGHQMA AETAIQRPNV PHLQTRDTYE 
       310        320        330        340        350        360 
GLCQTLGSQP THYQIPSLYC SYETNSSPYL LLQPARKEVV HLRPLIALYH DFVSDEEAQK 
       370        380        390        400        410        420 
IRELAEPWLQ RSVVASGEKQ LQVEYRISKS AWLKDTVDPM LVTLDHRIAA LTGLDIQPPY 
       430        440        450        460        470        480 
AEYLQVVNYG IGGHYEPHFD HATSPSSPLY RMKSGNRVAT FMIYLSSVEA GGATAFIYGN 
       490        500        510        520        530        540 
FSVPVVKNAA LFWWNLHRSG EGDGDTLHAG CPVLVGDKWV ANKWIHEYGQ EFRRPCSTNP 
   
ED



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6W3F0-25-unknown REDTFS... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6W3F0-139-unknown MRLQDV... 139 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt84047
    Q6W3F0-139-unknown MRLQDV... 139 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt84048

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)