TopFIND 4.0

Q6X9E4: F-box/WD repeat-containing protein 12

General Information

Protein names
- F-box/WD repeat-containing protein 12
- F-box and WD-40 domain-containing protein 12
- F-box only protein 35
Gene names FBXW12
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6X9E4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEIRLPDLAL KRIFSFLDLF GLLQVSQVNK HWNRIADSDY LWRSLSLQRW DCSNFTNQHL 
        70         80         90        100        110        120 
GTHTWKQFFL HQRRKELRLA LAQPHNFIYK VTKNIAFETE LAYLSGNRLT VDEQEKSIIC 
       130        140        150        160        170        180 
SVSPKQELCA WDVQEGTMIW SSPVQEFHFS NLVTLPQMHL AITMDRKKTI KVWNCQDRDA 
       190        200        210        220        230        240 
LAVLPMPQPC YCMEAYLTKD GPFLMVGDAA GDIYTFTLPG LRDVSKVTAF QYGIVLLHCS 
       250        260        270        280        290        300 
PDKKWVFACG TYSRTLPQVF LTESLLRPSE GSVPLSTFLP HKLCASACWT PKVKNRITLM 
       310        320        330        340        350        360 
SQSSTGKKTE FITFDLTTKK TGGQTVIQAY EIASFQVAAH LKCPIWMGAS DGYMIVFTSG 
       370        380        390        400        410        420 
PYLLLFSITG FLLQRFEDHQ AAINNFWVDP CYVLTTSENS VHVYMWEEGG RHPYLRSCCH 
       430        440        450        460    
LENTWHDHTT DSCISSVMCD NASIVLRVRK VSDSSILVMY SLNT

Isoforms

- Isoform 2 of F-box/WD repeat-containing protein 12 - Isoform 3 of F-box/WD repeat-containing protein 12

Sequence View

        10         20         30         40         50         60 
MEIRLPDLAL KRIFSFLDLF GLLQVSQVNK HWNRIADSDY LWRSLSLQRW DCSNFTNQHL 
        70         80         90        100        110        120 
GTHTWKQFFL HQRRKELRLA LAQPHNFIYK VTKNIAFETE LAYLSGNRLT VDEQEKSIIC 
       130        140        150        160        170        180 
SVSPKQELCA WDVQEGTMIW SSPVQEFHFS NLVTLPQMHL AITMDRKKTI KVWNCQDRDA 
       190        200        210        220        230        240 
LAVLPMPQPC YCMEAYLTKD GPFLMVGDAA GDIYTFTLPG LRDVSKVTAF QYGIVLLHCS 
       250        260        270        280        290        300 
PDKKWVFACG TYSRTLPQVF LTESLLRPSE GSVPLSTFLP HKLCASACWT PKVKNRITLM 
       310        320        330        340        350        360 
SQSSTGKKTE FITFDLTTKK TGGQTVIQAY EIASFQVAAH LKCPIWMGAS DGYMIVFTSG 
       370        380        390        400        410        420 
PYLLLFSITG FLLQRFEDHQ AAINNFWVDP CYVLTTSENS VHVYMWEEGG RHPYLRSCCH 
       430        440        450        460    
LENTWHDHTT DSCISSVMCD NASIVLRVRK VSDSSILVMY SLNT         10         20         30         40         50         60 
MEIRLPDLAL KRIFSFLDLF GLLQVSQVNK HWNRIADSDY LWRSLSLQRW DCSNFTNQHL 
        70         80         90        100        110        120 
GTHTWKQFFL HQRRKELRLA LAQPHNFIYK VTKNIAFETE LAYLSGNRLT VDEQEKSIIC 
       130        140        150        160        170        180 
SVSPKQELCA WDVQEGTMIW SSPVQEFHFS NLVTLPQMHL AITMDRKKTI KVWNCQDRDA 
       190        200        210        220        230        240 
LAVLPMPQPC YCMEAYLTKD GPFLMVGDAA GDIYTFTLPG LRDVSKVTAF QYGIVLLHCS 
       250        260        270        280        290        300 
PDKKWVFACG TYSRTLPQVF LTESLLRPSE GSVPLSTFLP HKLCASACWT PKVKNRITLM 
       310        320        330        340        350        360 
SQSSTGKKTE FITFDLTTKK TGGQTVIQAY EIASFQVAAH LKCPIWMGAS DGYMIVFTSG 
       370        380        390        400        410        420 
PYLLLFSITG FLLQRFEDHQ AAINNFWVDP CYVLTTSENS VHVYMWEEGG RHPYLRSCCH 
       430        440        450        460    
LENTWHDHTT DSCISSVMCD NASIVLRVRK VSDSSILVMY SLNT



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6X9E4-1-unknown MEIRLP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6X9E4-1-unknown MEIRLP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74880

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)