Q6XZB0: Lipase member I

General Information

Protein names	- Lipase member I - LIPI - 3.1.1.- - Cancer/testis antigen 17 - CT17 - LPD lipase - Membrane-associated phosphatidic acid-selective phospholipase A1-beta - mPA-PLA1 beta
Gene names	LIPI
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6XZB0

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Lipase member I - Isoform 3 of Lipase member I - Isoform 4 of Lipase member I - Isoform 5 of Lipase member I - Isoform 6 of Lipase member I - Isoform 7 of Lipase member I - Isoform 8 of Lipase member I - Isoform 2 of Lipase member I - Isoform 3 of Lipase member I - Isoform 4 of Lipase member I - Isoform 5 of Lipase member I - Isoform 8 of Lipase member I

Sequence View

        10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT         10         20         30         40         50         60
MRVYIFLCLM CWVRSDNKRP CLEFSQLSVK DSFRDLFIPR IETILMMYTR NNLNCAEPLF
        70         80         90        100        110        120
EQNNSLNVNF NTQKKTVWLI HGYRPVGSIP LWLQNFVRIL LNEEDMNVIV VDWSRGATTF
       130        140        150        160        170        180
IYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK IFHGQLGRIT
       190        200        210        220        230        240
GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGLGIQE PLGHIDFYPN GGNKQPGCPK
       250        260        270        280        290        300
SIFSGIQFIK CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD CFKEKSCPRL
       310        320        330        340        350        360
GYQAKLFKGV LKERMEGRPL RTTVFLDTSG TYPFCTYYFV LSIIVPDKTM MDGSFSFKLL
       370        380        390        400        410        420
NQLGMIEEPR LYEKNKPFYK LQEVKILAQF YNDFVNISSI GLTYFQSSNL QCSTCTYKIQ
       430        440        450        460
SLMLKSLTYP ERPPLCRYNI VLKDREEVFL NPNTCTPKNT

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6XZB0-1-unknown	MRVYIF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79656
Q6XZB0-1-unknown	MRVYIF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79657
Q6XZB0-1-unknown	MRVYIF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79658
Q6XZB0-1-unknown	MRVYIF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79659
Q6XZB0-1-unknown	MRVYIF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79660
Q6XZB0-16-unknown	DNKRPC...	16	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6XZB0-16-unknown	DNKRPC...	16	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111793
Q6XZB0-16-unknown	DNKRPC...	16	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111794
Q6XZB0-16-unknown	DNKRPC...	16	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111795
Q6XZB0-16-unknown	DNKRPC...	16	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111796
Q6XZB0-16-unknown	DNKRPC...	16	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111797
Q6XZB0-16-unknown	DNKRPC...	16	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111798

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TPKNT	460	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TPKNT	460	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75279
...TPKNT	460	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75275
...TPKNT	460	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75276
...TPKNT	460	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75274
...TPKNT	460	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75273

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)