TopFIND 4.0

Q6ZMJ4: Interleukin-34

General Information

Protein names
- Interleukin-34
- IL-34
Gene names IL34
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6ZMJ4

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPRGFTWLRY LGIFLGVALG NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI 
        70         80         90        100        110        120 
NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ 
       130        140        150        160        170        180 
EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC 
       190        200        210        220        230        240 
KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL 
   
LP

Isoforms

- Isoform 2 of Interleukin-34

Sequence View

        10         20         30         40         50         60 
MPRGFTWLRY LGIFLGVALG NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI 
        70         80         90        100        110        120 
NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ 
       130        140        150        160        170        180 
EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC 
       190        200        210        220        230        240 
KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL 
   
LP



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6ZMJ4-1-unknown MPRGFT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77778
    Q6ZMJ4-21-unknown NEPLEM... 21 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6ZMJ4-21-unknown NEPLEM... 21 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112692

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EGLLP 242 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EGLLP 242 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73396

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)