TopFIND 4.0

Q6ZNE9: RUN and FYVE domain-containing protein 4

General Information

Protein names
- RUN and FYVE domain-containing protein 4
Gene names RUFY4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6ZNE9

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAEEGAILKV TKDLRAAVSA ILQGYGDGQG PVTDTSAELH RLCGCLELLL QFDQKEQKSF 
        70         80         90        100        110        120 
LGPRKDYWDF LCTALRRQRG NMEPIHFVRS QDKLKTPLGK GRAFIRFCLA RGQLAEALQL 
       130        140        150        160        170        180 
CLLNSELTRE WYGPRSPLLC PERQEDILDS LYALNGVAFE LDLQQPDLDG AWPMFSESRC 
       190        200        210        220        230        240 
SSSTQTQGRR PRKNKDAPKK IPAAYGGPEN VQIEDSHTSQ AICLQDAPSG QQLAGLPRSQ 
       250        260        270        280        290        300 
QQRHLPFFLE KKGESSRKHR YPQSMWEPEG KELQLDQEER APWIEIFLGN STPSTQGQGK 
       310        320        330        340        350        360 
GAMGTQKEVI GMEAEVTGVL LVAEGQRTTE GTHKKEAEWS HVQRLLMPSP RGAVEGAVSG 
       370        380        390        400        410        420 
SRQGSGGSSI LGEPWVLQGH ATKEDSTVEN PQVQTEVTLV ARREEQAEVS LQDEIKSLRL 
       430        440        450        460        470        480 
GLRKAEEQAQ RQEQLLREQE GELQALREQL SRCQEERAEL QAQLEQKQQE AERRDAMYQE 
       490        500        510        520        530        540 
ELGGQRDLVQ AMKRRVLELI QEKDRLWQRL QHLSSMAPEC CVACSKIFGR FSRRYPCRLC 
       550        560        570    
GGLLCHACSM DYKKRDRCCP PCAQGREAQV T

Isoforms

- Isoform 2 of RUN and FYVE domain-containing protein 4

Sequence View

        10         20         30         40         50         60 
MAEEGAILKV TKDLRAAVSA ILQGYGDGQG PVTDTSAELH RLCGCLELLL QFDQKEQKSF 
        70         80         90        100        110        120 
LGPRKDYWDF LCTALRRQRG NMEPIHFVRS QDKLKTPLGK GRAFIRFCLA RGQLAEALQL 
       130        140        150        160        170        180 
CLLNSELTRE WYGPRSPLLC PERQEDILDS LYALNGVAFE LDLQQPDLDG AWPMFSESRC 
       190        200        210        220        230        240 
SSSTQTQGRR PRKNKDAPKK IPAAYGGPEN VQIEDSHTSQ AICLQDAPSG QQLAGLPRSQ 
       250        260        270        280        290        300 
QQRHLPFFLE KKGESSRKHR YPQSMWEPEG KELQLDQEER APWIEIFLGN STPSTQGQGK 
       310        320        330        340        350        360 
GAMGTQKEVI GMEAEVTGVL LVAEGQRTTE GTHKKEAEWS HVQRLLMPSP RGAVEGAVSG 
       370        380        390        400        410        420 
SRQGSGGSSI LGEPWVLQGH ATKEDSTVEN PQVQTEVTLV ARREEQAEVS LQDEIKSLRL 
       430        440        450        460        470        480 
GLRKAEEQAQ RQEQLLREQE GELQALREQL SRCQEERAEL QAQLEQKQQE AERRDAMYQE 
       490        500        510        520        530        540 
ELGGQRDLVQ AMKRRVLELI QEKDRLWQRL QHLSSMAPEC CVACSKIFGR FSRRYPCRLC 
       550        560        570    
GGLLCHACSM DYKKRDRCCP PCAQGREAQV T



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6ZNE9-1-unknown MAEEGA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6ZNE9-1-unknown MAEEGA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88393

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EAQVT 571 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)