Q6ZQ93: Ubiquitin carboxyl-terminal hydrolase 34
| Protein names | - Ubiquitin carboxyl-terminal hydrolase 34 - 3.4.19.12 {ECO:0000250|UniProtKB:Q70CQ2} - Deubiquitinating enzyme 34 - Ubiquitin thioesterase 34 - Ubiquitin-specific-processing protease 34 |
|---|---|
| Gene names | Usp34 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | C19.067 |
| Chromosome location | |
| UniProt ID | Q6ZQ93 |
1
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MCENCADLVE VLNEISDIEG GDGLQLRKEH TLKIFAYINS WTQRQCLCCF KEYKHLEIFN
70 80 90 100 110 120
QVVCALINLV IAQVQVLRDQ LCKHCTTINI DSTWQDESNQ AEEPLSIDRE CNEGNTERQK
130 140 150 160 170 180
SIEKKSNSTR TCNLTEEESS KSSDPFSLWN TDEKEKLLLC VAKIFQIQFP LYTAYKHNTH
190 200 210 220 230 240
PTIEDISTQE SNILGAFCDM NDVEVPLHLL RYVCLFCGKN GLSLMKDCFE YGTPETLPFL
250 260 270 280 290 300
IAHAFITVVS NIRIWLHIPA VMQHIIPFRT YVIRYLCKLS DQELRQSAAR NMADLMWSTV
310 320 330 340 350 360
KEPLDTTLCF DKESLDLAFK YFMSPTLTMR LAGLSQITNQ LHTFNDVCNN ESLVSDTETS
370 380 390 400 410 420
IAKELADWLI SNNVVEHIFG PNLHIEIIKQ CQVILNFLAA EGRLSTQHID CIWAAAQLKH
430 440 450 460 470 480
CSRYIHDLFP SLIKNLDPVP LRHLLNLVSA LEPGVHTEQT LYLASMLIKA LWNNALAAKA
490 500 510 520 530 540
QLSKQSSFAS LLNTNMPIGN KKEEEELRRA APSPWSPAAS PQSSDNSDTH QSGASDIEMD
550 560 570 580 590 600
EQLINRNKHV QQRLSDTEES MQGSSDETAN SGEDGSSGPG SSSGHSDGSS NEVNSSHASQ
610 620 630 640 650 660
SAGSPGSEVQ SEDIADIEAL KEEEEEEEEE EEEEEEEDDE EEEDEEEDDD DDDDHGHNPA
670 680 690 700 710 720
KNTCGTELRN RKLENPAGIC LGESQGTSER NGTNSGTGKD LVFNTEPLPS VDNRIRMLDA
730 740 750 760 770 780
CAHSEDPEHG ISGEVSSAHL AQGSQEACIT RSGDFLGETI GNELFNCRQF IGPQHHHHHH
790 800 810 820 830 840
HHHHHHHHHH HHHHHHHDGH MVDDMLSADD VSCSSSQVSA KSEKNMADFD GEESGCEEEL
850 860 870 880 890 900
VQINSHAELT SHLQQHLPNL ASIYHEHLSQ GPAVHKHQFS SNAVTDINLD NVCKKGNTLL
910 920 930 940 950 960
WDIVQDDDAI NLSEGLINEA EKLLCSLVCW FTDRQIRMRF IEGCLENLGN NRSVVISLRL
970 980 990 1000 1010 1020
LPKLFGTFQQ FGSSYDTHWI TMWAEKELNM MKLFFDNLVY YIQGIREGRQ KHALYSHSAE
1030 1040 1050 1060 1070 1080
VQVRLQFLTC VFSTLGSPDH FRLSLEQVDI LWHCLVEDSE CYDDALHWFL NQVRSKDQHA
1090 1100 1110 1120 1130 1140
MGMETYKHLF LEKMPQLKPE TISMTGLNLF QHLCNLARLA TSAYDGGSNS ELCGMDQFWG
1150 1160 1170 1180 1190 1200
IALRAQSGDV SRAAIQYINS YYINGKTGLE KEQEFISKCM ESLMIASSSL EQESHSSLTV
1210 1220 1230 1240 1250 1260
IERGLLMLKT HLEAFRRRFA YHLRQWQIEG TGISSHLKAL SDKQSLPLRV VCQPAGLPDK
1270 1280 1290 1300 1310 1320
MTIEMYPSDQ VADLRAEVTH WYENLQKEQI NQQAQLQEFG QSSRKGEFPG GLMGPVRMIS
1330 1340 1350 1360 1370 1380
SGHELTTDYD EKALHELGFK DMQMVFVSLG APRRERKGEG VQLPASCLPP PQKDNIPMLL
1390 1400 1410 1420 1430 1440
LLQEPHLTTL FDLLEMLASF KPPSGKVAVD DSESLKCEEL HLHAENLSRR VWELLMLLPT
1450 1460 1470 1480 1490 1500
CPNMLTAFQN VSDEQSNDGL NWKELLKIKS AHKLLYALEI IEALGKPNRR IRRESTGSYS
1510 1520 1530 1540 1550 1560
DLYPDSDDSS EDQVENSKNS WTCKFVAAGG LQQLLEIFNS AILEPKEQES WTVWQLDCLA
1570 1580 1590 1600 1610 1620
CLLKLICQFA VDPSDLDLAY HDVFAWSGIA ESHRKRTWPG KSRKAAGDHA KSLHIPRLTE
1630 1640 1650 1660 1670 1680
VFLVLVQGTS LIQRLMSVAY TYDNLAPRVL KAQSDHRSRH EVSHYSMWLL VSWAHCCSLV
1690 1700 1710 1720 1730 1740
KSSLADSDHL QDWLKQLTLL IPETAVRHES CNGLYKLSLS GLDGGDSIHR SFLLLAASTL
1750 1760 1770 1780 1790 1800
LKFLPDAQAL KPPRIDDYEE EPLLKPGCKE YFWLLCKLVD NIHIKDASQT TLLDLDALAR
1810 1820 1830 1840 1850 1860
HLADCIRSRE ILDHLDGSIE DDGLSGLLRL ATSVIKHKPP FKFSREGQEF LRDIFNLLFL
1870 1880 1890 1900 1910 1920
LPSLKDRRQP KCKSHSCRAA AYDLLVEMVK GSVENYRLIH NWVMAQHMQS HAPYKWDYWP
1930 1940 1950 1960 1970 1980
HEDVRAECRF VGLTNLGATC YLASTIQQLY MIPEARQAVF TAKYSEDMKH KTTLLELQKM
1990 2000 2010 2020 2030 2040
FTYLMESECK AYNPRPFCKT YTMDKQPLNT GEQKDMTEFF TDLITKVEEM SPELKNTVKS
2050 2060 2070 2080 2090 2100
LFGGVITNNV VSLDCEHVSQ TAEEFYTVRC QVADMKNIYE SLDEVTIKDT LEGDNMYTCS
2110 2120 2130 2140 2150 2160
HCGKKVRAEK RACFKKLPRI LSFNTMRYTF NMVTMMKEKV NTHFSFPLRL DMTPYTEDFL
2170 2180 2190 2200 2210 2220
MGKSDRKEGF KDVGDRSKDT ESYEYDLIGV TVHTGTADGG HYYSFIRDIV NPHAYKNNKW
2230 2240 2250 2260 2270 2280
YLFNDAEVKP FDSAQLASEC FGGEMTTKTY DSVTDKFMDF SFEKTHSAYM LFYKRMEPEE
2290 2300 2310 2320 2330 2340
ENGREYKFDV SSELLEWIWH DNMQFLQDKN IFEHTYFGFM WQLCSCIPST LPDPKAVSLM
2350 2360 2370 2380 2390 2400
TAKLSTSFVL ETFIHSKEKP TMLQWIELLT KQFNNSQAAC EWFLDRMADD DWWPMQILIK
2410 2420 2430 2440 2450 2460
CPNQIVRQMF QRLCIHVIQR LRPVHAHLYL QPGMEDGSDD MDASVEDIGG RSCVTRFVRT
2470 2480 2490 2500 2510 2520
LLLIMEHGVK PHSKHLTEYF AFLYEFAKMG EEESQFLLSL QAISTMVHFY MGTKGPENPQ
2530 2540 2550 2560 2570 2580
VEVLSEEEGE EEEEEEDILS LAEEKYRPAA LEKMIALVAL LVEQSRSERH LTLSQTDMAA
2590 2600 2610 2620 2630 2640
LTGGKGFPFL FQHIRDGINI RQTCNLIFSL CRYNNRLAEH IVSMLFTSIA KLTPEAANPF
2650 2660 2670 2680 2690 2700
FKLLTMLMEF AGGPPGMPPF ASYILQRIWE VIEYNPSQCL DWLAVQTPRN KLAHSWVLQN
2710 2720 2730 2740 2750 2760
MENWVERFLL AHNYPRVRTS AAYLLVSLIP SNSFRQMFRS TRSLHIPTRD LPLSPDTTVV
2770 2780 2790 2800 2810 2820
LHQVYNVLLG LLSRAKLYVD AAVHGTTKLV PYLSFMTYCL ISKTEKLMFS TYFMDLWNLF
2830 2840 2850 2860 2870 2880
QPKLSEPAIA TNHNKQALLS FWYNVCADCP ENIRLIVQNP VVTKNIAFNY ILADHDDQDV
2890 2900 2910 2920 2930 2940
VLFNRGMLPA YYGILRLCCE QSPAFTRQLA SHQNIQWAFK NLTPHASQYP GAVEELFNLM
2950 2960 2970 2980 2990 3000
QLFIAQRPDM REEELEDIKQ FKKTTISCYL RCLDGRSCWT TLISAFRILL ESDEDRLLVV
3010 3020 3030 3040 3050 3060
FNRGLILMTE SFNTLHMMYH EATACHVTGD LVELLSIFLS VLKSTRPYLQ RKDVKQALIQ
3070 3080 3090 3100 3110 3120
WQERIEFAHK LLTLLNSYSP PELRNACIDV LKELVLLSPH DFLHTLVPFL QHNHCTYHHS
3130 3140 3150 3160 3170 3180
NIPMSLGPYF PCRENIKLIG GKSNIRPPRP ELNMCLLPTM VETSKGKDDV YDRMLLDYFF
3190 3200 3210 3220 3230 3240
SYHQFIHLLC RVAINCEKFT ETLVKLSVLV AYEGLPLHLA LFPKLWTELC QTQSAMSKNC
3250 3260 3270 3280 3290 3300
IKLLCEDPVF AEYIKCILMD ERTFLNNNIV YTFMTHFLLK VQSQVFSEAN CASLISTLIT
3310 3320 3330 3340 3350 3360
NLINQYQNLQ SDFTNRVEIS KASAALNGDL RALALLLSVH TPKQLNPALI PTLQELLNKC
3370 3380 3390 3400 3410 3420
RTCLQQRNSL QEQEAKERKT KDDEGATPVK RRRVSSDEEH TVDSCIGDIK TETREVLTPT
3430 3440 3450 3460 3470 3480
STSDNETRDS SIIDPGTEQD LPSPENSSVK EYRMEGPSSF SEDGSHIRSQ HAEEQSNNGR
3490 3500 3510 3520 3530 3540
FDDCKEFKDH CSKDTTLAED ESEFPSTSIS AVLSDLADLR SCDGQALSSQ DPEAAVSLSC
3550 3560 3570 3580
GHSRGLISHM QQHDILDTLC RTIESTIHVV TRISGKGNQA AS
Isoforms
- Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 34 - Isoform 3 of Ubiquitin carboxyl-terminal hydrolase 34 - Isoform 4 of Ubiquitin carboxyl-terminal hydrolase 34Sequence View
10 20 30 40 50 60
MCENCADLVE VLNEISDIEG GDGLQLRKEH TLKIFAYINS WTQRQCLCCF KEYKHLEIFN
70 80 90 100 110 120
QVVCALINLV IAQVQVLRDQ LCKHCTTINI DSTWQDESNQ AEEPLSIDRE CNEGNTERQK
130 140 150 160 170 180
SIEKKSNSTR TCNLTEEESS KSSDPFSLWN TDEKEKLLLC VAKIFQIQFP LYTAYKHNTH
190 200 210 220 230 240
PTIEDISTQE SNILGAFCDM NDVEVPLHLL RYVCLFCGKN GLSLMKDCFE YGTPETLPFL
250 260 270 280 290 300
IAHAFITVVS NIRIWLHIPA VMQHIIPFRT YVIRYLCKLS DQELRQSAAR NMADLMWSTV
310 320 330 340 350 360
KEPLDTTLCF DKESLDLAFK YFMSPTLTMR LAGLSQITNQ LHTFNDVCNN ESLVSDTETS
370 380 390 400 410 420
IAKELADWLI SNNVVEHIFG PNLHIEIIKQ CQVILNFLAA EGRLSTQHID CIWAAAQLKH
430 440 450 460 470 480
CSRYIHDLFP SLIKNLDPVP LRHLLNLVSA LEPGVHTEQT LYLASMLIKA LWNNALAAKA
490 500 510 520 530 540
QLSKQSSFAS LLNTNMPIGN KKEEEELRRA APSPWSPAAS PQSSDNSDTH QSGASDIEMD
550 560 570 580 590 600
EQLINRNKHV QQRLSDTEES MQGSSDETAN SGEDGSSGPG SSSGHSDGSS NEVNSSHASQ
610 620 630 640 650 660
SAGSPGSEVQ SEDIADIEAL KEEEEEEEEE EEEEEEEDDE EEEDEEEDDD DDDDHGHNPA
670 680 690 700 710 720
KNTCGTELRN RKLENPAGIC LGESQGTSER NGTNSGTGKD LVFNTEPLPS VDNRIRMLDA
730 740 750 760 770 780
CAHSEDPEHG ISGEVSSAHL AQGSQEACIT RSGDFLGETI GNELFNCRQF IGPQHHHHHH
790 800 810 820 830 840
HHHHHHHHHH HHHHHHHDGH MVDDMLSADD VSCSSSQVSA KSEKNMADFD GEESGCEEEL
850 860 870 880 890 900
VQINSHAELT SHLQQHLPNL ASIYHEHLSQ GPAVHKHQFS SNAVTDINLD NVCKKGNTLL
910 920 930 940 950 960
WDIVQDDDAI NLSEGLINEA EKLLCSLVCW FTDRQIRMRF IEGCLENLGN NRSVVISLRL
970 980 990 1000 1010 1020
LPKLFGTFQQ FGSSYDTHWI TMWAEKELNM MKLFFDNLVY YIQGIREGRQ KHALYSHSAE
1030 1040 1050 1060 1070 1080
VQVRLQFLTC VFSTLGSPDH FRLSLEQVDI LWHCLVEDSE CYDDALHWFL NQVRSKDQHA
1090 1100 1110 1120 1130 1140
MGMETYKHLF LEKMPQLKPE TISMTGLNLF QHLCNLARLA TSAYDGGSNS ELCGMDQFWG
1150 1160 1170 1180 1190 1200
IALRAQSGDV SRAAIQYINS YYINGKTGLE KEQEFISKCM ESLMIASSSL EQESHSSLTV
1210 1220 1230 1240 1250 1260
IERGLLMLKT HLEAFRRRFA YHLRQWQIEG TGISSHLKAL SDKQSLPLRV VCQPAGLPDK
1270 1280 1290 1300 1310 1320
MTIEMYPSDQ VADLRAEVTH WYENLQKEQI NQQAQLQEFG QSSRKGEFPG GLMGPVRMIS
1330 1340 1350 1360 1370 1380
SGHELTTDYD EKALHELGFK DMQMVFVSLG APRRERKGEG VQLPASCLPP PQKDNIPMLL
1390 1400 1410 1420 1430 1440
LLQEPHLTTL FDLLEMLASF KPPSGKVAVD DSESLKCEEL HLHAENLSRR VWELLMLLPT
1450 1460 1470 1480 1490 1500
CPNMLTAFQN VSDEQSNDGL NWKELLKIKS AHKLLYALEI IEALGKPNRR IRRESTGSYS
1510 1520 1530 1540 1550 1560
DLYPDSDDSS EDQVENSKNS WTCKFVAAGG LQQLLEIFNS AILEPKEQES WTVWQLDCLA
1570 1580 1590 1600 1610 1620
CLLKLICQFA VDPSDLDLAY HDVFAWSGIA ESHRKRTWPG KSRKAAGDHA KSLHIPRLTE
1630 1640 1650 1660 1670 1680
VFLVLVQGTS LIQRLMSVAY TYDNLAPRVL KAQSDHRSRH EVSHYSMWLL VSWAHCCSLV
1690 1700 1710 1720 1730 1740
KSSLADSDHL QDWLKQLTLL IPETAVRHES CNGLYKLSLS GLDGGDSIHR SFLLLAASTL
1750 1760 1770 1780 1790 1800
LKFLPDAQAL KPPRIDDYEE EPLLKPGCKE YFWLLCKLVD NIHIKDASQT TLLDLDALAR
1810 1820 1830 1840 1850 1860
HLADCIRSRE ILDHLDGSIE DDGLSGLLRL ATSVIKHKPP FKFSREGQEF LRDIFNLLFL
1870 1880 1890 1900 1910 1920
LPSLKDRRQP KCKSHSCRAA AYDLLVEMVK GSVENYRLIH NWVMAQHMQS HAPYKWDYWP
1930 1940 1950 1960 1970 1980
HEDVRAECRF VGLTNLGATC YLASTIQQLY MIPEARQAVF TAKYSEDMKH KTTLLELQKM
1990 2000 2010 2020 2030 2040
FTYLMESECK AYNPRPFCKT YTMDKQPLNT GEQKDMTEFF TDLITKVEEM SPELKNTVKS
2050 2060 2070 2080 2090 2100
LFGGVITNNV VSLDCEHVSQ TAEEFYTVRC QVADMKNIYE SLDEVTIKDT LEGDNMYTCS
2110 2120 2130 2140 2150 2160
HCGKKVRAEK RACFKKLPRI LSFNTMRYTF NMVTMMKEKV NTHFSFPLRL DMTPYTEDFL
2170 2180 2190 2200 2210 2220
MGKSDRKEGF KDVGDRSKDT ESYEYDLIGV TVHTGTADGG HYYSFIRDIV NPHAYKNNKW
2230 2240 2250 2260 2270 2280
YLFNDAEVKP FDSAQLASEC FGGEMTTKTY DSVTDKFMDF SFEKTHSAYM LFYKRMEPEE
2290 2300 2310 2320 2330 2340
ENGREYKFDV SSELLEWIWH DNMQFLQDKN IFEHTYFGFM WQLCSCIPST LPDPKAVSLM
2350 2360 2370 2380 2390 2400
TAKLSTSFVL ETFIHSKEKP TMLQWIELLT KQFNNSQAAC EWFLDRMADD DWWPMQILIK
2410 2420 2430 2440 2450 2460
CPNQIVRQMF QRLCIHVIQR LRPVHAHLYL QPGMEDGSDD MDASVEDIGG RSCVTRFVRT
2470 2480 2490 2500 2510 2520
LLLIMEHGVK PHSKHLTEYF AFLYEFAKMG EEESQFLLSL QAISTMVHFY MGTKGPENPQ
2530 2540 2550 2560 2570 2580
VEVLSEEEGE EEEEEEDILS LAEEKYRPAA LEKMIALVAL LVEQSRSERH LTLSQTDMAA
2590 2600 2610 2620 2630 2640
LTGGKGFPFL FQHIRDGINI RQTCNLIFSL CRYNNRLAEH IVSMLFTSIA KLTPEAANPF
2650 2660 2670 2680 2690 2700
FKLLTMLMEF AGGPPGMPPF ASYILQRIWE VIEYNPSQCL DWLAVQTPRN KLAHSWVLQN
2710 2720 2730 2740 2750 2760
MENWVERFLL AHNYPRVRTS AAYLLVSLIP SNSFRQMFRS TRSLHIPTRD LPLSPDTTVV
2770 2780 2790 2800 2810 2820
LHQVYNVLLG LLSRAKLYVD AAVHGTTKLV PYLSFMTYCL ISKTEKLMFS TYFMDLWNLF
2830 2840 2850 2860 2870 2880
QPKLSEPAIA TNHNKQALLS FWYNVCADCP ENIRLIVQNP VVTKNIAFNY ILADHDDQDV
2890 2900 2910 2920 2930 2940
VLFNRGMLPA YYGILRLCCE QSPAFTRQLA SHQNIQWAFK NLTPHASQYP GAVEELFNLM
2950 2960 2970 2980 2990 3000
QLFIAQRPDM REEELEDIKQ FKKTTISCYL RCLDGRSCWT TLISAFRILL ESDEDRLLVV
3010 3020 3030 3040 3050 3060
FNRGLILMTE SFNTLHMMYH EATACHVTGD LVELLSIFLS VLKSTRPYLQ RKDVKQALIQ
3070 3080 3090 3100 3110 3120
WQERIEFAHK LLTLLNSYSP PELRNACIDV LKELVLLSPH DFLHTLVPFL QHNHCTYHHS
3130 3140 3150 3160 3170 3180
NIPMSLGPYF PCRENIKLIG GKSNIRPPRP ELNMCLLPTM VETSKGKDDV YDRMLLDYFF
3190 3200 3210 3220 3230 3240
SYHQFIHLLC RVAINCEKFT ETLVKLSVLV AYEGLPLHLA LFPKLWTELC QTQSAMSKNC
3250 3260 3270 3280 3290 3300
IKLLCEDPVF AEYIKCILMD ERTFLNNNIV YTFMTHFLLK VQSQVFSEAN CASLISTLIT
3310 3320 3330 3340 3350 3360
NLINQYQNLQ SDFTNRVEIS KASAALNGDL RALALLLSVH TPKQLNPALI PTLQELLNKC
3370 3380 3390 3400 3410 3420
RTCLQQRNSL QEQEAKERKT KDDEGATPVK RRRVSSDEEH TVDSCIGDIK TETREVLTPT
3430 3440 3450 3460 3470 3480
STSDNETRDS SIIDPGTEQD LPSPENSSVK EYRMEGPSSF SEDGSHIRSQ HAEEQSNNGR
3490 3500 3510 3520 3530 3540
FDDCKEFKDH CSKDTTLAED ESEFPSTSIS AVLSDLADLR SCDGQALSSQ DPEAAVSLSC
3550 3560 3570 3580
GHSRGLISHM QQHDILDTLC RTIESTIHVV TRISGKGNQA AS
10 20 30 40 50 60
MCENCADLVE VLNEISDIEG GDGLQLRKEH TLKIFAYINS WTQRQCLCCF KEYKHLEIFN
70 80 90 100 110 120
QVVCALINLV IAQVQVLRDQ LCKHCTTINI DSTWQDESNQ AEEPLSIDRE CNEGNTERQK
130 140 150 160 170 180
SIEKKSNSTR TCNLTEEESS KSSDPFSLWN TDEKEKLLLC VAKIFQIQFP LYTAYKHNTH
190 200 210 220 230 240
PTIEDISTQE SNILGAFCDM NDVEVPLHLL RYVCLFCGKN GLSLMKDCFE YGTPETLPFL
250 260 270 280 290 300
IAHAFITVVS NIRIWLHIPA VMQHIIPFRT YVIRYLCKLS DQELRQSAAR NMADLMWSTV
310 320 330 340 350 360
KEPLDTTLCF DKESLDLAFK YFMSPTLTMR LAGLSQITNQ LHTFNDVCNN ESLVSDTETS
370 380 390 400 410 420
IAKELADWLI SNNVVEHIFG PNLHIEIIKQ CQVILNFLAA EGRLSTQHID CIWAAAQLKH
430 440 450 460 470 480
CSRYIHDLFP SLIKNLDPVP LRHLLNLVSA LEPGVHTEQT LYLASMLIKA LWNNALAAKA
490 500 510 520 530 540
QLSKQSSFAS LLNTNMPIGN KKEEEELRRA APSPWSPAAS PQSSDNSDTH QSGASDIEMD
550 560 570 580 590 600
EQLINRNKHV QQRLSDTEES MQGSSDETAN SGEDGSSGPG SSSGHSDGSS NEVNSSHASQ
610 620 630 640 650 660
SAGSPGSEVQ SEDIADIEAL KEEEEEEEEE EEEEEEEDDE EEEDEEEDDD DDDDHGHNPA
670 680 690 700 710 720
KNTCGTELRN RKLENPAGIC LGESQGTSER NGTNSGTGKD LVFNTEPLPS VDNRIRMLDA
730 740 750 760 770 780
CAHSEDPEHG ISGEVSSAHL AQGSQEACIT RSGDFLGETI GNELFNCRQF IGPQHHHHHH
790 800 810 820 830 840
HHHHHHHHHH HHHHHHHDGH MVDDMLSADD VSCSSSQVSA KSEKNMADFD GEESGCEEEL
850 860 870 880 890 900
VQINSHAELT SHLQQHLPNL ASIYHEHLSQ GPAVHKHQFS SNAVTDINLD NVCKKGNTLL
910 920 930 940 950 960
WDIVQDDDAI NLSEGLINEA EKLLCSLVCW FTDRQIRMRF IEGCLENLGN NRSVVISLRL
970 980 990 1000 1010 1020
LPKLFGTFQQ FGSSYDTHWI TMWAEKELNM MKLFFDNLVY YIQGIREGRQ KHALYSHSAE
1030 1040 1050 1060 1070 1080
VQVRLQFLTC VFSTLGSPDH FRLSLEQVDI LWHCLVEDSE CYDDALHWFL NQVRSKDQHA
1090 1100 1110 1120 1130 1140
MGMETYKHLF LEKMPQLKPE TISMTGLNLF QHLCNLARLA TSAYDGGSNS ELCGMDQFWG
1150 1160 1170 1180 1190 1200
IALRAQSGDV SRAAIQYINS YYINGKTGLE KEQEFISKCM ESLMIASSSL EQESHSSLTV
1210 1220 1230 1240 1250 1260
IERGLLMLKT HLEAFRRRFA YHLRQWQIEG TGISSHLKAL SDKQSLPLRV VCQPAGLPDK
1270 1280 1290 1300 1310 1320
MTIEMYPSDQ VADLRAEVTH WYENLQKEQI NQQAQLQEFG QSSRKGEFPG GLMGPVRMIS
1330 1340 1350 1360 1370 1380
SGHELTTDYD EKALHELGFK DMQMVFVSLG APRRERKGEG VQLPASCLPP PQKDNIPMLL
1390 1400 1410 1420 1430 1440
LLQEPHLTTL FDLLEMLASF KPPSGKVAVD DSESLKCEEL HLHAENLSRR VWELLMLLPT
1450 1460 1470 1480 1490 1500
CPNMLTAFQN VSDEQSNDGL NWKELLKIKS AHKLLYALEI IEALGKPNRR IRRESTGSYS
1510 1520 1530 1540 1550 1560
DLYPDSDDSS EDQVENSKNS WTCKFVAAGG LQQLLEIFNS AILEPKEQES WTVWQLDCLA
1570 1580 1590 1600 1610 1620
CLLKLICQFA VDPSDLDLAY HDVFAWSGIA ESHRKRTWPG KSRKAAGDHA KSLHIPRLTE
1630 1640 1650 1660 1670 1680
VFLVLVQGTS LIQRLMSVAY TYDNLAPRVL KAQSDHRSRH EVSHYSMWLL VSWAHCCSLV
1690 1700 1710 1720 1730 1740
KSSLADSDHL QDWLKQLTLL IPETAVRHES CNGLYKLSLS GLDGGDSIHR SFLLLAASTL
1750 1760 1770 1780 1790 1800
LKFLPDAQAL KPPRIDDYEE EPLLKPGCKE YFWLLCKLVD NIHIKDASQT TLLDLDALAR
1810 1820 1830 1840 1850 1860
HLADCIRSRE ILDHLDGSIE DDGLSGLLRL ATSVIKHKPP FKFSREGQEF LRDIFNLLFL
1870 1880 1890 1900 1910 1920
LPSLKDRRQP KCKSHSCRAA AYDLLVEMVK GSVENYRLIH NWVMAQHMQS HAPYKWDYWP
1930 1940 1950 1960 1970 1980
HEDVRAECRF VGLTNLGATC YLASTIQQLY MIPEARQAVF TAKYSEDMKH KTTLLELQKM
1990 2000 2010 2020 2030 2040
FTYLMESECK AYNPRPFCKT YTMDKQPLNT GEQKDMTEFF TDLITKVEEM SPELKNTVKS
2050 2060 2070 2080 2090 2100
LFGGVITNNV VSLDCEHVSQ TAEEFYTVRC QVADMKNIYE SLDEVTIKDT LEGDNMYTCS
2110 2120 2130 2140 2150 2160
HCGKKVRAEK RACFKKLPRI LSFNTMRYTF NMVTMMKEKV NTHFSFPLRL DMTPYTEDFL
2170 2180 2190 2200 2210 2220
MGKSDRKEGF KDVGDRSKDT ESYEYDLIGV TVHTGTADGG HYYSFIRDIV NPHAYKNNKW
2230 2240 2250 2260 2270 2280
YLFNDAEVKP FDSAQLASEC FGGEMTTKTY DSVTDKFMDF SFEKTHSAYM LFYKRMEPEE
2290 2300 2310 2320 2330 2340
ENGREYKFDV SSELLEWIWH DNMQFLQDKN IFEHTYFGFM WQLCSCIPST LPDPKAVSLM
2350 2360 2370 2380 2390 2400
TAKLSTSFVL ETFIHSKEKP TMLQWIELLT KQFNNSQAAC EWFLDRMADD DWWPMQILIK
2410 2420 2430 2440 2450 2460
CPNQIVRQMF QRLCIHVIQR LRPVHAHLYL QPGMEDGSDD MDASVEDIGG RSCVTRFVRT
2470 2480 2490 2500 2510 2520
LLLIMEHGVK PHSKHLTEYF AFLYEFAKMG EEESQFLLSL QAISTMVHFY MGTKGPENPQ
2530 2540 2550 2560 2570 2580
VEVLSEEEGE EEEEEEDILS LAEEKYRPAA LEKMIALVAL LVEQSRSERH LTLSQTDMAA
2590 2600 2610 2620 2630 2640
LTGGKGFPFL FQHIRDGINI RQTCNLIFSL CRYNNRLAEH IVSMLFTSIA KLTPEAANPF
2650 2660 2670 2680 2690 2700
FKLLTMLMEF AGGPPGMPPF ASYILQRIWE VIEYNPSQCL DWLAVQTPRN KLAHSWVLQN
2710 2720 2730 2740 2750 2760
MENWVERFLL AHNYPRVRTS AAYLLVSLIP SNSFRQMFRS TRSLHIPTRD LPLSPDTTVV
2770 2780 2790 2800 2810 2820
LHQVYNVLLG LLSRAKLYVD AAVHGTTKLV PYLSFMTYCL ISKTEKLMFS TYFMDLWNLF
2830 2840 2850 2860 2870 2880
QPKLSEPAIA TNHNKQALLS FWYNVCADCP ENIRLIVQNP VVTKNIAFNY ILADHDDQDV
2890 2900 2910 2920 2930 2940
VLFNRGMLPA YYGILRLCCE QSPAFTRQLA SHQNIQWAFK NLTPHASQYP GAVEELFNLM
2950 2960 2970 2980 2990 3000
QLFIAQRPDM REEELEDIKQ FKKTTISCYL RCLDGRSCWT TLISAFRILL ESDEDRLLVV
3010 3020 3030 3040 3050 3060
FNRGLILMTE SFNTLHMMYH EATACHVTGD LVELLSIFLS VLKSTRPYLQ RKDVKQALIQ
3070 3080 3090 3100 3110 3120
WQERIEFAHK LLTLLNSYSP PELRNACIDV LKELVLLSPH DFLHTLVPFL QHNHCTYHHS
3130 3140 3150 3160 3170 3180
NIPMSLGPYF PCRENIKLIG GKSNIRPPRP ELNMCLLPTM VETSKGKDDV YDRMLLDYFF
3190 3200 3210 3220 3230 3240
SYHQFIHLLC RVAINCEKFT ETLVKLSVLV AYEGLPLHLA LFPKLWTELC QTQSAMSKNC
3250 3260 3270 3280 3290 3300
IKLLCEDPVF AEYIKCILMD ERTFLNNNIV YTFMTHFLLK VQSQVFSEAN CASLISTLIT
3310 3320 3330 3340 3350 3360
NLINQYQNLQ SDFTNRVEIS KASAALNGDL RALALLLSVH TPKQLNPALI PTLQELLNKC
3370 3380 3390 3400 3410 3420
RTCLQQRNSL QEQEAKERKT KDDEGATPVK RRRVSSDEEH TVDSCIGDIK TETREVLTPT
3430 3440 3450 3460 3470 3480
STSDNETRDS SIIDPGTEQD LPSPENSSVK EYRMEGPSSF SEDGSHIRSQ HAEEQSNNGR
3490 3500 3510 3520 3530 3540
FDDCKEFKDH CSKDTTLAED ESEFPSTSIS AVLSDLADLR SCDGQALSSQ DPEAAVSLSC
3550 3560 3570 3580
GHSRGLISHM QQHDILDTLC RTIESTIHVV TRISGKGNQA AS
10 20 30 40 50 60
MCENCADLVE VLNEISDIEG GDGLQLRKEH TLKIFAYINS WTQRQCLCCF KEYKHLEIFN
70 80 90 100 110 120
QVVCALINLV IAQVQVLRDQ LCKHCTTINI DSTWQDESNQ AEEPLSIDRE CNEGNTERQK
130 140 150 160 170 180
SIEKKSNSTR TCNLTEEESS KSSDPFSLWN TDEKEKLLLC VAKIFQIQFP LYTAYKHNTH
190 200 210 220 230 240
PTIEDISTQE SNILGAFCDM NDVEVPLHLL RYVCLFCGKN GLSLMKDCFE YGTPETLPFL
250 260 270 280 290 300
IAHAFITVVS NIRIWLHIPA VMQHIIPFRT YVIRYLCKLS DQELRQSAAR NMADLMWSTV
310 320 330 340 350 360
KEPLDTTLCF DKESLDLAFK YFMSPTLTMR LAGLSQITNQ LHTFNDVCNN ESLVSDTETS
370 380 390 400 410 420
IAKELADWLI SNNVVEHIFG PNLHIEIIKQ CQVILNFLAA EGRLSTQHID CIWAAAQLKH
430 440 450 460 470 480
CSRYIHDLFP SLIKNLDPVP LRHLLNLVSA LEPGVHTEQT LYLASMLIKA LWNNALAAKA
490 500 510 520 530 540
QLSKQSSFAS LLNTNMPIGN KKEEEELRRA APSPWSPAAS PQSSDNSDTH QSGASDIEMD
550 560 570 580 590 600
EQLINRNKHV QQRLSDTEES MQGSSDETAN SGEDGSSGPG SSSGHSDGSS NEVNSSHASQ
610 620 630 640 650 660
SAGSPGSEVQ SEDIADIEAL KEEEEEEEEE EEEEEEEDDE EEEDEEEDDD DDDDHGHNPA
670 680 690 700 710 720
KNTCGTELRN RKLENPAGIC LGESQGTSER NGTNSGTGKD LVFNTEPLPS VDNRIRMLDA
730 740 750 760 770 780
CAHSEDPEHG ISGEVSSAHL AQGSQEACIT RSGDFLGETI GNELFNCRQF IGPQHHHHHH
790 800 810 820 830 840
HHHHHHHHHH HHHHHHHDGH MVDDMLSADD VSCSSSQVSA KSEKNMADFD GEESGCEEEL
850 860 870 880 890 900
VQINSHAELT SHLQQHLPNL ASIYHEHLSQ GPAVHKHQFS SNAVTDINLD NVCKKGNTLL
910 920 930 940 950 960
WDIVQDDDAI NLSEGLINEA EKLLCSLVCW FTDRQIRMRF IEGCLENLGN NRSVVISLRL
970 980 990 1000 1010 1020
LPKLFGTFQQ FGSSYDTHWI TMWAEKELNM MKLFFDNLVY YIQGIREGRQ KHALYSHSAE
1030 1040 1050 1060 1070 1080
VQVRLQFLTC VFSTLGSPDH FRLSLEQVDI LWHCLVEDSE CYDDALHWFL NQVRSKDQHA
1090 1100 1110 1120 1130 1140
MGMETYKHLF LEKMPQLKPE TISMTGLNLF QHLCNLARLA TSAYDGGSNS ELCGMDQFWG
1150 1160 1170 1180 1190 1200
IALRAQSGDV SRAAIQYINS YYINGKTGLE KEQEFISKCM ESLMIASSSL EQESHSSLTV
1210 1220 1230 1240 1250 1260
IERGLLMLKT HLEAFRRRFA YHLRQWQIEG TGISSHLKAL SDKQSLPLRV VCQPAGLPDK
1270 1280 1290 1300 1310 1320
MTIEMYPSDQ VADLRAEVTH WYENLQKEQI NQQAQLQEFG QSSRKGEFPG GLMGPVRMIS
1330 1340 1350 1360 1370 1380
SGHELTTDYD EKALHELGFK DMQMVFVSLG APRRERKGEG VQLPASCLPP PQKDNIPMLL
1390 1400 1410 1420 1430 1440
LLQEPHLTTL FDLLEMLASF KPPSGKVAVD DSESLKCEEL HLHAENLSRR VWELLMLLPT
1450 1460 1470 1480 1490 1500
CPNMLTAFQN VSDEQSNDGL NWKELLKIKS AHKLLYALEI IEALGKPNRR IRRESTGSYS
1510 1520 1530 1540 1550 1560
DLYPDSDDSS EDQVENSKNS WTCKFVAAGG LQQLLEIFNS AILEPKEQES WTVWQLDCLA
1570 1580 1590 1600 1610 1620
CLLKLICQFA VDPSDLDLAY HDVFAWSGIA ESHRKRTWPG KSRKAAGDHA KSLHIPRLTE
1630 1640 1650 1660 1670 1680
VFLVLVQGTS LIQRLMSVAY TYDNLAPRVL KAQSDHRSRH EVSHYSMWLL VSWAHCCSLV
1690 1700 1710 1720 1730 1740
KSSLADSDHL QDWLKQLTLL IPETAVRHES CNGLYKLSLS GLDGGDSIHR SFLLLAASTL
1750 1760 1770 1780 1790 1800
LKFLPDAQAL KPPRIDDYEE EPLLKPGCKE YFWLLCKLVD NIHIKDASQT TLLDLDALAR
1810 1820 1830 1840 1850 1860
HLADCIRSRE ILDHLDGSIE DDGLSGLLRL ATSVIKHKPP FKFSREGQEF LRDIFNLLFL
1870 1880 1890 1900 1910 1920
LPSLKDRRQP KCKSHSCRAA AYDLLVEMVK GSVENYRLIH NWVMAQHMQS HAPYKWDYWP
1930 1940 1950 1960 1970 1980
HEDVRAECRF VGLTNLGATC YLASTIQQLY MIPEARQAVF TAKYSEDMKH KTTLLELQKM
1990 2000 2010 2020 2030 2040
FTYLMESECK AYNPRPFCKT YTMDKQPLNT GEQKDMTEFF TDLITKVEEM SPELKNTVKS
2050 2060 2070 2080 2090 2100
LFGGVITNNV VSLDCEHVSQ TAEEFYTVRC QVADMKNIYE SLDEVTIKDT LEGDNMYTCS
2110 2120 2130 2140 2150 2160
HCGKKVRAEK RACFKKLPRI LSFNTMRYTF NMVTMMKEKV NTHFSFPLRL DMTPYTEDFL
2170 2180 2190 2200 2210 2220
MGKSDRKEGF KDVGDRSKDT ESYEYDLIGV TVHTGTADGG HYYSFIRDIV NPHAYKNNKW
2230 2240 2250 2260 2270 2280
YLFNDAEVKP FDSAQLASEC FGGEMTTKTY DSVTDKFMDF SFEKTHSAYM LFYKRMEPEE
2290 2300 2310 2320 2330 2340
ENGREYKFDV SSELLEWIWH DNMQFLQDKN IFEHTYFGFM WQLCSCIPST LPDPKAVSLM
2350 2360 2370 2380 2390 2400
TAKLSTSFVL ETFIHSKEKP TMLQWIELLT KQFNNSQAAC EWFLDRMADD DWWPMQILIK
2410 2420 2430 2440 2450 2460
CPNQIVRQMF QRLCIHVIQR LRPVHAHLYL QPGMEDGSDD MDASVEDIGG RSCVTRFVRT
2470 2480 2490 2500 2510 2520
LLLIMEHGVK PHSKHLTEYF AFLYEFAKMG EEESQFLLSL QAISTMVHFY MGTKGPENPQ
2530 2540 2550 2560 2570 2580
VEVLSEEEGE EEEEEEDILS LAEEKYRPAA LEKMIALVAL LVEQSRSERH LTLSQTDMAA
2590 2600 2610 2620 2630 2640
LTGGKGFPFL FQHIRDGINI RQTCNLIFSL CRYNNRLAEH IVSMLFTSIA KLTPEAANPF
2650 2660 2670 2680 2690 2700
FKLLTMLMEF AGGPPGMPPF ASYILQRIWE VIEYNPSQCL DWLAVQTPRN KLAHSWVLQN
2710 2720 2730 2740 2750 2760
MENWVERFLL AHNYPRVRTS AAYLLVSLIP SNSFRQMFRS TRSLHIPTRD LPLSPDTTVV
2770 2780 2790 2800 2810 2820
LHQVYNVLLG LLSRAKLYVD AAVHGTTKLV PYLSFMTYCL ISKTEKLMFS TYFMDLWNLF
2830 2840 2850 2860 2870 2880
QPKLSEPAIA TNHNKQALLS FWYNVCADCP ENIRLIVQNP VVTKNIAFNY ILADHDDQDV
2890 2900 2910 2920 2930 2940
VLFNRGMLPA YYGILRLCCE QSPAFTRQLA SHQNIQWAFK NLTPHASQYP GAVEELFNLM
2950 2960 2970 2980 2990 3000
QLFIAQRPDM REEELEDIKQ FKKTTISCYL RCLDGRSCWT TLISAFRILL ESDEDRLLVV
3010 3020 3030 3040 3050 3060
FNRGLILMTE SFNTLHMMYH EATACHVTGD LVELLSIFLS VLKSTRPYLQ RKDVKQALIQ
3070 3080 3090 3100 3110 3120
WQERIEFAHK LLTLLNSYSP PELRNACIDV LKELVLLSPH DFLHTLVPFL QHNHCTYHHS
3130 3140 3150 3160 3170 3180
NIPMSLGPYF PCRENIKLIG GKSNIRPPRP ELNMCLLPTM VETSKGKDDV YDRMLLDYFF
3190 3200 3210 3220 3230 3240
SYHQFIHLLC RVAINCEKFT ETLVKLSVLV AYEGLPLHLA LFPKLWTELC QTQSAMSKNC
3250 3260 3270 3280 3290 3300
IKLLCEDPVF AEYIKCILMD ERTFLNNNIV YTFMTHFLLK VQSQVFSEAN CASLISTLIT
3310 3320 3330 3340 3350 3360
NLINQYQNLQ SDFTNRVEIS KASAALNGDL RALALLLSVH TPKQLNPALI PTLQELLNKC
3370 3380 3390 3400 3410 3420
RTCLQQRNSL QEQEAKERKT KDDEGATPVK RRRVSSDEEH TVDSCIGDIK TETREVLTPT
3430 3440 3450 3460 3470 3480
STSDNETRDS SIIDPGTEQD LPSPENSSVK EYRMEGPSSF SEDGSHIRSQ HAEEQSNNGR
3490 3500 3510 3520 3530 3540
FDDCKEFKDH CSKDTTLAED ESEFPSTSIS AVLSDLADLR SCDGQALSSQ DPEAAVSLSC
3550 3560 3570 3580
GHSRGLISHM QQHDILDTLC RTIESTIHVV TRISGKGNQA AS
Protein Neighborhood
Domains & Features
1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q6ZQ93-1-unknown | MCENCA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...QSRSER | 2568 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89305 | |||
| ...QSRSER | 2568 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93825 | |||
| ...QSRSER | 2568 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93826 | |||
| ...NQAAS | 3582 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...NQAAS | 3582 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89304 | |||
| ...NQAAS | 3582 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89303 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|