Q6ZQA0: Neurobeachin-like protein 2
| Protein names | - Neurobeachin-like protein 2 |
|---|---|
| Gene names | Nbeal2 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q6ZQA0 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAASERLYEL WLLYYAQKDL GYLQQWLKAF VGVFEKTISL SSLEPRRPEE AGAEVPLLPL
70 80 90 100 110 120
DALHALAEQL DQDDLDQALL LLKLFIILCR NLENVEAGWG QVLVPRVLAL LTVLMAELKG
130 140 150 160 170 180
SSQESHGTQL ENVALHALLL CEGLFDPYQT WRRQLTGEVI SSKEKSKYKF PPAALPCEFG
190 200 210 220 230 240
AFFQENLQDA ERLPPTLLLR LIHLFGAILA GGKANGQMAV SAGSVQGLLG VVRGWGRGPA
250 260 270 280 290 300
QDPQQVPLAL RALVGAVHVL HASRAPPRGP ELRTLLEGYF HILNADWPTS PSSSPEEALV
310 320 330 340 350 360
TLRVSMLDAI PMMLACEDRP VLQATFLSNN CFEHLIRLIQ NSKLYLQARA PPEGDSDLAT
370 380 390 400 410 420
WLLTEPDVQK VLDQDTDAIA VHVVRVLTCI MSGSPSAKEV FKERIGYQHL QEVLQSHGPP
430 440 450 460 470 480
THRLLQELLN MAVEGDHSMH PPPPIRNEQP VLVLMQWLPA LPTAELRLFL AQRLWWLCDS
490 500 510 520 530 540
CPASRTTCVQ AGLVGYLLET LNTGTALGAR CQEQLLALLQ ALGRVSLRPL ELRRLLRPPP
550 560 570 580 590 600
GLDSESSGNE SQKARHAGAV IRALSGMARH RGPARALRYF DLTPSMAGIM VPPVQRWPGA
610 620 630 640 650 660
GFTFHAWLCL QSSEAVPTSA PSRPLQRKQL YSFFTSSGSG FEAFFTAAGT LVVAVCTRKE
670 680 690 700 710 720
YVTVNLPEVS FADSAWHCVA IVHVPGRRPF SQNLVNVFKD GHLVKTVPFR FPSLSEPFSS
730 740 750 760 770 780
CCIGSAGHRT TTTTTGLPAS SVSTALAHTH PSLTRSQSVP ASTGLGWGPG LGTPLQEGSV
790 800 810 820 830 840
SSTLAGTQDT RWGSPTSLEG ELGAVAIFHE ALQPSALRVL CSLGPNEPAP FKPEGELHEF
850 860 870 880 890 900
GTKLLLHYSP QACKNNICLD LSPGHGLDGR LTGHRVETWD VKDVVNCVGG MGVLLPLLER
910 920 930 940 950 960
VAVQPQEAEA GPCETHDLVG PELTSGRNTQ GLLLPLGKSS EDRMERNAVA AFLLMLRNFL
970 980 990 1000 1010 1020
QNHTVNQESL VQCQGPAIIG ALLRKVPSSA MDMNVLMSAQ LLMEQAAADG GGPLLYLLYQ
1030 1040 1050 1060 1070 1080
HLLFNFHLWT LSDFAVRLGH IQYMSSMVRE HRQKLRKKYG VQFLLDALRT HYSPQRERPL
1090 1100 1110 1120 1130 1140
AADDLRTVQT SLLGLVREFL VRNFSVEDMQ VVLNFLAATG DDGQVVGTLE LLLTLLQGSP
1150 1160 1170 1180 1190 1200
VQDPLAAFLL ELGNLEVLLA LLVRPKSTPL LTDRVCKILR RLQQNERLPE RNRQRIRLHD
1210 1220 1230 1240 1250 1260
CGLQGLVASL SEESISPQLC QGLYKLFVGT DCLNLSDLLA VVQLSLQADL SVRLDICRQL
1270 1280 1290 1300 1310 1320
FYLIYGQPDV VRLLARQAGW QDVLTRLYVL EAATDSSPPR FLPELPISSE LALSPPPTEL
1330 1340 1350 1360 1370 1380
PADSSDVFLP SESPCPDQDA FYQALSPFST PFDLGLERAS IGSGNTAGGG SSNGTVTPAS
1390 1400 1410 1420 1430 1440
QPGTPSPLDG PRPFPTAQGR HSSSLSNVLE DGSLLEPNIS GDDTSNTSNP QQTPEEELCN
1450 1460 1470 1480 1490 1500
LLTNVLFSVT WRGVEGSAEA AWRERGQVFS VLTQLGASAT LVRPPDCIKR SLLEMMLESA
1510 1520 1530 1540 1550 1560
LTDIKEAPPG GLANLSQQAL WLLRLLQDFL CAEGHGNQEL WSEKLFEGVC NLLDRLGAWP
1570 1580 1590 1600 1610 1620
HLANSTADLR EMAQIGLRLV LGYILLEDPQ LHAQAYVKLH TLLQTAVPTR REEACYVLSK
1630 1640 1650 1660 1670 1680
LEAALSRALT TSSSETEHAS TAVAASERCS WLVPLVRTLL DRAYGPLGLQ WGLPSLPPTN
1690 1700 1710 1720 1730 1740
GSPTFFEDFQ AFCATAEWRH FIDKQVQPTM SKFEMDTYAK SHDLMSGFWN ACYDTLMSSG
1750 1760 1770 1780 1790 1800
QRHQRDRIQS RRAFKELVLE PAQRRARVEG LRYASVLKQQ AAQHSTALLH WGALWRQLSS
1810 1820 1830 1840 1850 1860
PCGAWALRIP PAPHWKLSSA ETYSRMRLKL VPNHHFDPHL EASALRDNLG EAPMTPTEET
1870 1880 1890 1900 1910 1920
SLPLAVTKEA KISAPPEELP EEQLGEEDLA ALESLMEAAE LDEKREKLVL SAECQLVTVV
1930 1940 1950 1960 1970 1980
AVVPGLLEIT TQHVYFYDGS TERVETEEGI GHDFRRPLAQ LREVHLRRFN LRRSALELFF
1990 2000 2010 2020 2030 2040
IDQSNYFLNF PHKVAASSAS SPCQAPRPQL YPIPSHTQLR NQVYSLLLRL RPPTQGYLSS
2050 2060 2070 2080 2090 2100
RSPLEMLRAS GLTQKWVQRE ISNFEYLMQL NTIAGRTYND LSQYPVFPWV LQDYVSPVLD
2110 2120 2130 2140 2150 2160
LSNPAVFRDL SKPIGVVNPK HAQLVREKYE SFEDPAGTID KFHYGTHYSN AAGVMHYLIR
2170 2180 2190 2200 2210 2220
VEPFTSLHVQ LQSGRFDCSD RQFHSVAAAW QARLESPADV KELIPEFFYF PDFLENQNGF
2230 2240 2250 2260 2270 2280
DLGCLQLTNE KVGDVVLPPW AGSPEDFIQK HRQALESEYV STHLHEWIDL IFGYKQRGPA
2290 2300 2310 2320 2330 2340
AEEALNVFYY CTYEGAVDLD HVADERERKA LEGIISNFGQ TPCQLLKEPH PPRLSAEEAA
2350 2360 2370 2380 2390 2400
NRLARLDTNS PSIFQNLNQL KAFFAEVVSE AVPLVLALVP HRQSHSFITQ SSSDMLVTVS
2410 2420 2430 2440 2450 2460
ASGLLGTHTW LPYDRNINNY FTFSKDPTMG SPKVQKLLSG PWVSDSGVSA QALAVAPDGK
2470 2480 2490 2500 2510 2520
LLFSGGHWDG SLRVTSLPRG RLLNQLSRHL DIVTCLALDT CGIYLISGSR DTTCMVWRLL
2530 2540 2550 2560 2570 2580
QQSGLSAGLA PKPVQVLYGH VAAVSCVAIS TELDMAVSGS EDGTVIIHTV RRGQFVAALR
2590 2600 2610 2620 2630 2640
PPGATLPGPI SHLALGAEGQ IVVQSSACER PGAQVTYSLH LYSVNGRLRA SVTLTEQPTA
2650 2660 2670 2680 2690 2700
LTVAEDFVLL GTAQCSLHIL HLNKLRPAVP PLPMKVPVHS VSVTKERSHV LVGLEDGKLI
2710 2720 2730 2740
VVGAGQPSEV RSSQFARRLW RSSRRISQVS SGETEYNPGE AR
Isoforms
- Isoform 2 of Neurobeachin-like protein 2Sequence View
10 20 30 40 50 60
MAASERLYEL WLLYYAQKDL GYLQQWLKAF VGVFEKTISL SSLEPRRPEE AGAEVPLLPL
70 80 90 100 110 120
DALHALAEQL DQDDLDQALL LLKLFIILCR NLENVEAGWG QVLVPRVLAL LTVLMAELKG
130 140 150 160 170 180
SSQESHGTQL ENVALHALLL CEGLFDPYQT WRRQLTGEVI SSKEKSKYKF PPAALPCEFG
190 200 210 220 230 240
AFFQENLQDA ERLPPTLLLR LIHLFGAILA GGKANGQMAV SAGSVQGLLG VVRGWGRGPA
250 260 270 280 290 300
QDPQQVPLAL RALVGAVHVL HASRAPPRGP ELRTLLEGYF HILNADWPTS PSSSPEEALV
310 320 330 340 350 360
TLRVSMLDAI PMMLACEDRP VLQATFLSNN CFEHLIRLIQ NSKLYLQARA PPEGDSDLAT
370 380 390 400 410 420
WLLTEPDVQK VLDQDTDAIA VHVVRVLTCI MSGSPSAKEV FKERIGYQHL QEVLQSHGPP
430 440 450 460 470 480
THRLLQELLN MAVEGDHSMH PPPPIRNEQP VLVLMQWLPA LPTAELRLFL AQRLWWLCDS
490 500 510 520 530 540
CPASRTTCVQ AGLVGYLLET LNTGTALGAR CQEQLLALLQ ALGRVSLRPL ELRRLLRPPP
550 560 570 580 590 600
GLDSESSGNE SQKARHAGAV IRALSGMARH RGPARALRYF DLTPSMAGIM VPPVQRWPGA
610 620 630 640 650 660
GFTFHAWLCL QSSEAVPTSA PSRPLQRKQL YSFFTSSGSG FEAFFTAAGT LVVAVCTRKE
670 680 690 700 710 720
YVTVNLPEVS FADSAWHCVA IVHVPGRRPF SQNLVNVFKD GHLVKTVPFR FPSLSEPFSS
730 740 750 760 770 780
CCIGSAGHRT TTTTTGLPAS SVSTALAHTH PSLTRSQSVP ASTGLGWGPG LGTPLQEGSV
790 800 810 820 830 840
SSTLAGTQDT RWGSPTSLEG ELGAVAIFHE ALQPSALRVL CSLGPNEPAP FKPEGELHEF
850 860 870 880 890 900
GTKLLLHYSP QACKNNICLD LSPGHGLDGR LTGHRVETWD VKDVVNCVGG MGVLLPLLER
910 920 930 940 950 960
VAVQPQEAEA GPCETHDLVG PELTSGRNTQ GLLLPLGKSS EDRMERNAVA AFLLMLRNFL
970 980 990 1000 1010 1020
QNHTVNQESL VQCQGPAIIG ALLRKVPSSA MDMNVLMSAQ LLMEQAAADG GGPLLYLLYQ
1030 1040 1050 1060 1070 1080
HLLFNFHLWT LSDFAVRLGH IQYMSSMVRE HRQKLRKKYG VQFLLDALRT HYSPQRERPL
1090 1100 1110 1120 1130 1140
AADDLRTVQT SLLGLVREFL VRNFSVEDMQ VVLNFLAATG DDGQVVGTLE LLLTLLQGSP
1150 1160 1170 1180 1190 1200
VQDPLAAFLL ELGNLEVLLA LLVRPKSTPL LTDRVCKILR RLQQNERLPE RNRQRIRLHD
1210 1220 1230 1240 1250 1260
CGLQGLVASL SEESISPQLC QGLYKLFVGT DCLNLSDLLA VVQLSLQADL SVRLDICRQL
1270 1280 1290 1300 1310 1320
FYLIYGQPDV VRLLARQAGW QDVLTRLYVL EAATDSSPPR FLPELPISSE LALSPPPTEL
1330 1340 1350 1360 1370 1380
PADSSDVFLP SESPCPDQDA FYQALSPFST PFDLGLERAS IGSGNTAGGG SSNGTVTPAS
1390 1400 1410 1420 1430 1440
QPGTPSPLDG PRPFPTAQGR HSSSLSNVLE DGSLLEPNIS GDDTSNTSNP QQTPEEELCN
1450 1460 1470 1480 1490 1500
LLTNVLFSVT WRGVEGSAEA AWRERGQVFS VLTQLGASAT LVRPPDCIKR SLLEMMLESA
1510 1520 1530 1540 1550 1560
LTDIKEAPPG GLANLSQQAL WLLRLLQDFL CAEGHGNQEL WSEKLFEGVC NLLDRLGAWP
1570 1580 1590 1600 1610 1620
HLANSTADLR EMAQIGLRLV LGYILLEDPQ LHAQAYVKLH TLLQTAVPTR REEACYVLSK
1630 1640 1650 1660 1670 1680
LEAALSRALT TSSSETEHAS TAVAASERCS WLVPLVRTLL DRAYGPLGLQ WGLPSLPPTN
1690 1700 1710 1720 1730 1740
GSPTFFEDFQ AFCATAEWRH FIDKQVQPTM SKFEMDTYAK SHDLMSGFWN ACYDTLMSSG
1750 1760 1770 1780 1790 1800
QRHQRDRIQS RRAFKELVLE PAQRRARVEG LRYASVLKQQ AAQHSTALLH WGALWRQLSS
1810 1820 1830 1840 1850 1860
PCGAWALRIP PAPHWKLSSA ETYSRMRLKL VPNHHFDPHL EASALRDNLG EAPMTPTEET
1870 1880 1890 1900 1910 1920
SLPLAVTKEA KISAPPEELP EEQLGEEDLA ALESLMEAAE LDEKREKLVL SAECQLVTVV
1930 1940 1950 1960 1970 1980
AVVPGLLEIT TQHVYFYDGS TERVETEEGI GHDFRRPLAQ LREVHLRRFN LRRSALELFF
1990 2000 2010 2020 2030 2040
IDQSNYFLNF PHKVAASSAS SPCQAPRPQL YPIPSHTQLR NQVYSLLLRL RPPTQGYLSS
2050 2060 2070 2080 2090 2100
RSPLEMLRAS GLTQKWVQRE ISNFEYLMQL NTIAGRTYND LSQYPVFPWV LQDYVSPVLD
2110 2120 2130 2140 2150 2160
LSNPAVFRDL SKPIGVVNPK HAQLVREKYE SFEDPAGTID KFHYGTHYSN AAGVMHYLIR
2170 2180 2190 2200 2210 2220
VEPFTSLHVQ LQSGRFDCSD RQFHSVAAAW QARLESPADV KELIPEFFYF PDFLENQNGF
2230 2240 2250 2260 2270 2280
DLGCLQLTNE KVGDVVLPPW AGSPEDFIQK HRQALESEYV STHLHEWIDL IFGYKQRGPA
2290 2300 2310 2320 2330 2340
AEEALNVFYY CTYEGAVDLD HVADERERKA LEGIISNFGQ TPCQLLKEPH PPRLSAEEAA
2350 2360 2370 2380 2390 2400
NRLARLDTNS PSIFQNLNQL KAFFAEVVSE AVPLVLALVP HRQSHSFITQ SSSDMLVTVS
2410 2420 2430 2440 2450 2460
ASGLLGTHTW LPYDRNINNY FTFSKDPTMG SPKVQKLLSG PWVSDSGVSA QALAVAPDGK
2470 2480 2490 2500 2510 2520
LLFSGGHWDG SLRVTSLPRG RLLNQLSRHL DIVTCLALDT CGIYLISGSR DTTCMVWRLL
2530 2540 2550 2560 2570 2580
QQSGLSAGLA PKPVQVLYGH VAAVSCVAIS TELDMAVSGS EDGTVIIHTV RRGQFVAALR
2590 2600 2610 2620 2630 2640
PPGATLPGPI SHLALGAEGQ IVVQSSACER PGAQVTYSLH LYSVNGRLRA SVTLTEQPTA
2650 2660 2670 2680 2690 2700
LTVAEDFVLL GTAQCSLHIL HLNKLRPAVP PLPMKVPVHS VSVTKERSHV LVGLEDGKLI
2710 2720 2730 2740
VVGAGQPSEV RSSQFARRLW RSSRRISQVS SGETEYNPGE AR
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q6ZQA0-1-unknown | MAASER... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q6ZQA0-1-unknown | MAASER... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt82347 | |||
| Q6ZQA0-2700-unknown | IVVGAG... | 2700 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30648 | |||
| Q6ZQA0-2700-unknown | IVVGAG... | 2700 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159242 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...EDGKLI | 2699 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30648 | |||
| ...EDGKLI | 2699 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142746 | |||
| ...PGEAR | 2742 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...PGEAR | 2742 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt77965 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CATE_MOUSE | 2699 | GKLI.|.IVVG | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> NBEL2_MOUSE @2699 |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|