TopFIND 4.0

Q6ZRR7: Leucine-rich repeat-containing protein 9

General Information

Protein names
- Leucine-rich repeat-containing protein 9
Gene names LRRC9
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6ZRR7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MIESENLNQE EIIKELCLCN GLSYEMVGQE GSDTSKLEMF FLGYPRIVGL SLFPNLTSLT 
        70         80         90        100        110        120 
IVAQDIKEIS GLEPCLQLKE LWIAECCIEK IEGLQECRNL EKLYLYFNKI SKIENLEKLI 
       130        140        150        160        170        180 
KLKVLWLNHN TIKNIEGLQT LKNLKDLNLA GNLINSIGRC LDSNEQLERL NLSGNQICSF 
       190        200        210        220        230        240 
KELTNLTRLP CLKDLCLNDP QYTTNPVCLL CNYSTHVLYH LPCLQRFDTL DVSAKQIKEL 
       250        260        270        280        290        300 
ADTTAMKKIM YYNMRIKTLQ RHLKEDLEKL NDQKCKLQKL PEERVKLFSF VKKTLERELA 
       310        320        330        340        350        360 
ELKGSGKGHS DGSNNSKVTD PETLKSCETV TEEPSLQQKI LAKLNALNER VTFWNKKLDE 
       370        380        390        400        410        420 
IEAIYHIEVK QKKKSHGLLI PLLLIELETV GNFHFEEGTR SDDWFNFCYE LILSRFCAWD 
       430        440        450        460        470        480 
FRTYGITGVK VKRIIKVNNR ILRLKFEEKF QKFLENEDMH DSESYRRMLE CLFYVFDPEV 
       490        500        510        520        530        540 
SVKKKHLLQI LEKGFKDSET SKLPLKKEAI IVSNSLSISE CPRIEFLQQK HKDEKKISLK 
       550        560        570        580        590        600 
HELFRHGILL ITKVFLGQSV QAHEKESISQ SNYPMVNSVF IPRKYLLNSV MGQRNCDCSV 
       610        620        630        640        650        660 
RQCKWFVFDH DLVLPEYVVE FEYITMVKAP SLFSVFNNVI LEESKKNPEV SVFSKDLKFD 
       670        680        690        700        710        720 
DEVIKMEPRI KARPKLISLD DKTILSLAKT SVYSHIVSLN LHGNSLSKLR DLSKLTGLRK 
       730        740        750        760        770        780 
LNISFNEFTC LDDVYHLYNL EYLDASHNHV ITLEGFRGLM KLKHLDLSWN QLKKSGNEIN 
       790        800        810        820        830        840 
MLCKHTTSLL TLDIQHNPWQ KPATLRLSVI GRLKTLTHLN GVFISEEEAT AAMKFIAGTR 
       850        860        870        880        890        900 
ITQLSLLRHS STKEERPRIL SIWPSAKILT QVSKLGPHLH LSGNCYLKIT ALNLDGQHLF 
       910        920        930        940        950        960 
EITNLEKLEN LKWASFSNNN LTKMEGLESC INLEELTLDG NCISKIEGIS KMTKLTRLSI 
       970        980        990       1000       1010       1020 
NNNLLTGWEE HTFDNMLHLH SLSLENNRIT SLSGLQKSFT LVELYISNNY IAVNQEMHNL 
      1030       1040       1050       1060       1070       1080 
KGLCNLVILD MCGNIIIWNQ ENYRLFVIFH LPELKALDGI PIEPSETDSA KDLFGGRLTS 
      1090       1100       1110       1120       1130       1140 
DMIAERQGHS NFKQMQELNW TSSSIRTVDL IPVDQFRNVC NVNLQNNHLT SFSGLIYLPN 
      1150       1160       1170       1180       1190       1200 
VKVLCLNYNH IESIMPRLKP QTHLTSRQLL YQKVPSSGYG QQGISKTNRD IMSSENLPPI 
      1210       1220       1230       1240       1250       1260 
MHSLEVLHLG YNGICNLIQL QLNRLRNLKF LFLQGNEISQ VEGLDNLVVL QELVVDHNRI 
      1270       1280       1290       1300       1310       1320 
RSFNDSAFAK PSSLLALHLE ENRLRELGKL QSLVKLEKLF LGYNKIQDIT ELEKLDVIST 
      1330       1340       1350       1360       1370       1380 
LRELTVYGNP ICRKMLHRHM LIFRLPNLQM LDGSPVNSDD RAKAEFHLAE LQAKKNSLIP 
      1390       1400       1410       1420       1430       1440 
VTHSPMDGRS FGQVKTPPIE ITNVLLPSGF SHYLGSDVTL TPEVEEFLGA TFQDQIECNC 
      1450    
LKRNEHTPRN SPV

Isoforms

- Isoform 2 of Leucine-rich repeat-containing protein 9

Sequence View

        10         20         30         40         50         60 
MIESENLNQE EIIKELCLCN GLSYEMVGQE GSDTSKLEMF FLGYPRIVGL SLFPNLTSLT 
        70         80         90        100        110        120 
IVAQDIKEIS GLEPCLQLKE LWIAECCIEK IEGLQECRNL EKLYLYFNKI SKIENLEKLI 
       130        140        150        160        170        180 
KLKVLWLNHN TIKNIEGLQT LKNLKDLNLA GNLINSIGRC LDSNEQLERL NLSGNQICSF 
       190        200        210        220        230        240 
KELTNLTRLP CLKDLCLNDP QYTTNPVCLL CNYSTHVLYH LPCLQRFDTL DVSAKQIKEL 
       250        260        270        280        290        300 
ADTTAMKKIM YYNMRIKTLQ RHLKEDLEKL NDQKCKLQKL PEERVKLFSF VKKTLERELA 
       310        320        330        340        350        360 
ELKGSGKGHS DGSNNSKVTD PETLKSCETV TEEPSLQQKI LAKLNALNER VTFWNKKLDE 
       370        380        390        400        410        420 
IEAIYHIEVK QKKKSHGLLI PLLLIELETV GNFHFEEGTR SDDWFNFCYE LILSRFCAWD 
       430        440        450        460        470        480 
FRTYGITGVK VKRIIKVNNR ILRLKFEEKF QKFLENEDMH DSESYRRMLE CLFYVFDPEV 
       490        500        510        520        530        540 
SVKKKHLLQI LEKGFKDSET SKLPLKKEAI IVSNSLSISE CPRIEFLQQK HKDEKKISLK 
       550        560        570        580        590        600 
HELFRHGILL ITKVFLGQSV QAHEKESISQ SNYPMVNSVF IPRKYLLNSV MGQRNCDCSV 
       610        620        630        640        650        660 
RQCKWFVFDH DLVLPEYVVE FEYITMVKAP SLFSVFNNVI LEESKKNPEV SVFSKDLKFD 
       670        680        690        700        710        720 
DEVIKMEPRI KARPKLISLD DKTILSLAKT SVYSHIVSLN LHGNSLSKLR DLSKLTGLRK 
       730        740        750        760        770        780 
LNISFNEFTC LDDVYHLYNL EYLDASHNHV ITLEGFRGLM KLKHLDLSWN QLKKSGNEIN 
       790        800        810        820        830        840 
MLCKHTTSLL TLDIQHNPWQ KPATLRLSVI GRLKTLTHLN GVFISEEEAT AAMKFIAGTR 
       850        860        870        880        890        900 
ITQLSLLRHS STKEERPRIL SIWPSAKILT QVSKLGPHLH LSGNCYLKIT ALNLDGQHLF 
       910        920        930        940        950        960 
EITNLEKLEN LKWASFSNNN LTKMEGLESC INLEELTLDG NCISKIEGIS KMTKLTRLSI 
       970        980        990       1000       1010       1020 
NNNLLTGWEE HTFDNMLHLH SLSLENNRIT SLSGLQKSFT LVELYISNNY IAVNQEMHNL 
      1030       1040       1050       1060       1070       1080 
KGLCNLVILD MCGNIIIWNQ ENYRLFVIFH LPELKALDGI PIEPSETDSA KDLFGGRLTS 
      1090       1100       1110       1120       1130       1140 
DMIAERQGHS NFKQMQELNW TSSSIRTVDL IPVDQFRNVC NVNLQNNHLT SFSGLIYLPN 
      1150       1160       1170       1180       1190       1200 
VKVLCLNYNH IESIMPRLKP QTHLTSRQLL YQKVPSSGYG QQGISKTNRD IMSSENLPPI 
      1210       1220       1230       1240       1250       1260 
MHSLEVLHLG YNGICNLIQL QLNRLRNLKF LFLQGNEISQ VEGLDNLVVL QELVVDHNRI 
      1270       1280       1290       1300       1310       1320 
RSFNDSAFAK PSSLLALHLE ENRLRELGKL QSLVKLEKLF LGYNKIQDIT ELEKLDVIST 
      1330       1340       1350       1360       1370       1380 
LRELTVYGNP ICRKMLHRHM LIFRLPNLQM LDGSPVNSDD RAKAEFHLAE LQAKKNSLIP 
      1390       1400       1410       1420       1430       1440 
VTHSPMDGRS FGQVKTPPIE ITNVLLPSGF SHYLGSDVTL TPEVEEFLGA TFQDQIECNC 
      1450    
LKRNEHTPRN SPV



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6ZRR7-1-unknown MIESEN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6ZRR7-1-unknown MIESEN... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79973

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RNSPV 1453 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)