Q6ZWQ0: Nesprin-2
| Protein names | - Nesprin-2 - KASH domain-containing protein 2 - KASH2 - Nuclear envelope spectrin repeat protein 2 - Nucleus and actin connecting element protein - Protein NUANCE - Synaptic nuclear envelope protein 2 - Syne-2 |
|---|---|
| Gene names | Syne2 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q6ZWQ0 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAASPVLPTE DGEGFLGIDD LHFSLQAEQE DTQKKTFTCW INSQLAKHTP PSVVSDLFAD
70 80 90 100 110 120
IKKGHVLLDL LEVLSGQQLP RDKGSNTFQC RINIEHALTF LKNRSIKLIN IHVADIVEGN
130 140 150 160 170 180
PSIILGLIWT IILHFHIEKL AQTLSCDYNQ PSPEVVSVAA SSPTSSPPTK KCSKAQAQAR
190 200 210 220 230 240
WQWSAKKALL QWAQEQCARS ESVNVTDFKS SWRNGMAFLA VIHALRPDLI DMDSMRHRSN
250 260 270 280 290 300
KDNLKEAFRI AEHELKIPKL LEPEDVDVVN PDEKSIMTYV AQFLKYSKDA PGPGDSTQAK
310 320 330 340 350 360
VRDALVWLTL QEKRFQKMLK DSASETYCNK YHSLLSFMES LNEEKESFID VLSLKGRMGE
370 380 390 400 410 420
LNEDESRLRQ GWTSLMHQVA AWRAQLDDAL PSPLKETEAW LKDIEGVVQE GVPTSQSYSE
430 440 450 460 470 480
ARTLIQGKLS SFKSLMGSFD YHSDVLMAFQ SNAEKSLPAV PPVKLEEMTR RINNVLGKNF
490 500 510 520 530 540
IPLLEFHDSK CSVLALLDEA KAKLDVWNGT YESKESVEVL LEDWHKFTGE KKFLIQLDAS
550 560 570 580 590 600
FQKCEEMYKN SARECESIRE EYMMLEKNVH SCRQYIHNTK ATLQRALMSW ATFEEDLALL
610 620 630 640 650 660
KASFDLTKKE QIKEVPVETL LQWNTKHTSL NEVGSFLIGV SSREVAASIS KELRRLNKRW
670 680 690 700 710 720
RKFITKTPLL KLPLVKIQDQ PPGNSSGTSL SKESAMAAEP GGSRGEDVKA AEKQEVEDEE
730 740 750 760 770 780
SAGQLKVNEE VEGLIKQVTI WESQTKSILD LLQHGDHADG SSADTLQHLI AKGSVYEELL
790 800 810 820 830 840
ARTEDTLQMD VQSPSNLEPF QNVLRAGLQA KIQEAKQGVQ ITMVELSAVL KNLSDEPLEL
850 860 870 880 890 900
DLGLKVEEAQ KELEVSILRA EQLLGQRERP GGFLLKYKEA LEILNTNSLA KYLRAVEELK
910 920 930 940 950 960
RTVPGGAKLQ LEEQSRVASA KWEPLRHEIS LYLQQLKIAI EEEKLRDNIA RLEKQINKEK
970 980 990 1000 1010 1020
KLIRRGRTRG LRKEHEACLS PESIKCQLEH HVGVLRVLCE ELTSPEDQQE LKRALRDYEQ
1030 1040 1050 1060 1070 1080
KIARLLKCAS EIHTTLQSSQ GGALEERSAL ITTENGRRDA DGEVPLEIPD NQLSTEKAME
1090 1100 1110 1120 1130 1140
PIKNFSQTSE LKPQQEESIM EKEGKDCSAS LSDLQERYDT QRGLLEQHLQ DSKSRVTSDF
1150 1160 1170 1180 1190 1200
ASEQERSSAC LQSKLAELQV LLADTDAHWE KFEITSLNLR RLMSDAEKPV LNQERDLLKG
1210 1220 1230 1240 1250 1260
NEQVLHGLLN TRMESLEMAL QIVLPLEKEC SLLCASDLPL CTVAVQDLHP VEIDGVYQNL
1270 1280 1290 1300 1310 1320
RDIRDSIAKQ IRVCTSLEEP SNSVPRELHT LDQCAIQDIV LKCRLQLETM NQKVEMREDA
1330 1340 1350 1360 1370 1380
LDALEGFLAS LRAAKLSAEL PADRPAPKAP EVLSEDILLM KEKAGPLDER LRTLGINIKD
1390 1400 1410 1420 1430 1440
AEGGENTTCE RLVGALSVNL VAMDGQSKEE GPPEDKKLLE ACSSKNLELF KNIQDLQNQI
1450 1460 1470 1480 1490 1500
SKIGLKDPTA PAVKHRKKSL LRLDKDLDGL EEEKVRIQKI AGSLPRFKDG SEKNVIQQCE
1510 1520 1530 1540 1550 1560
DTAALWESTK ASVTESLEQC GSALELLRQY QNIKNNLTAL IQKEEGIISQ QASYMGKDNL
1570 1580 1590 1600 1610 1620
KKKIAEIETV KEEFSDHLEV VDKINQICKN LQYHLNKMKT FEDPPFEKEA NAIVDRWLDI
1630 1640 1650 1660 1670 1680
NEKTEEYGEN LGRALALWDK LFIIKNNIDE WTEQILGKAE SHELTEEDRG RLKEELKVLE
1690 1700 1710 1720 1730 1740
EQSAEFSRRV ADIQSLLQSN EKPLELQVME SSVLSKMKDV KTHVAGGSNS YAPSGSTAEL
1750 1760 1770 1780 1790 1800
REDLDQAKTQ MGMTESLLNA LSPSDSLEIF TKLEEIQQQI FQQKHSMTVL ENQIGCLTPE
1810 1820 1830 1840 1850 1860
LSELKRQYAS VSNLFNTKKN ALQDHFATFL NEQCKNFNDW FSNVKTNLQE CFEPPETKLS
1870 1880 1890 1900 1910 1920
LEQRLQKLSD FLTLGGGNSK IQQVETVLQH VKMLLPKAHV KELDSWLRSQ ELELENMESI
1930 1940 1950 1960 1970 1980
CQARAGELNN SFQQLLRLED DCRSLSKWLT NQEENWGKME VSGERMDLFS QALTRKREQF
1990 2000 2010 2020 2030 2040
ETVAQLSDSL KEHGLTEGEE TIKESTHLID RYQALWRQLH EIEEEDKLPA AEDQSFNDLA
2050 2060 2070 2080 2090 2100
DDVIHWIKEI KESLMALNSS EGKMPLEERI QKIKEIIALK PEGDAKIQMV MRQAEHCEAP
2110 2120 2130 2140 2150 2160
LAQETFTDLS NQWDSTLHLA NTYLSHQEKL VLEGEKYLQS KEDLRLMLTE LKKQQEAGFA
2170 2180 2190 2200 2210 2220
LQPGLPEKQA QLKIYKKFLQ KAQDLTSLLE ELKSQGNYLL ECTKNPSFSE EPWLEVKHLH
2230 2240 2250 2260 2270 2280
ESLLQQLQDS VQKLEGHVQE HSSYQVCLTD LSSTLDDISK EYFSLCDGSK DQIMAKERMQ
2290 2300 2310 2320 2330 2340
KLQELESRLR FQGGALKKAS ALAKSIKQNT SSVGQKIIKD DIRSLKYKQK DLENRIESAK
2350 2360 2370 2380 2390 2400
QETENGLNSI LKSKSSTEKH VKFSLPVEEM PATSEVPKPT RESAAVGESG GARETNTNSA
2410 2420 2430 2440 2450 2460
VEMILSKQLS LNVQESMQNA QDEREVNELQ NQPLELDIML RNEQLKGMEE LSTHLEARRA
2470 2480 2490 2500 2510 2520
AIELLEQSQH LNQTEEQALV LPAARPSVCH LGSLQQELHT LKKTKERQYG LLSGFQDQLV
2530 2540 2550 2560 2570 2580
MAEASLNTSL AEVESLKIGS LDSATYLGKI KKFLGSVENQ QGSLSKLRTE WAHLSSLLAA
2590 2600 2610 2620 2630 2640
ADQKLVESQM KHLEHGWELV EQLAHRKCFQ QATEHSELTC LLEKLQDLKV SLHQQQQRLT
2650 2660 2670 2680 2690 2700
LSLNSPGQQA AIVDMVTPAA ELQAIKCEFS GLKWQAELHM KRLWGEKDKK TLEDAINNLN
2710 2720 2730 2740 2750 2760
KQMEALEPLN REVENRIKKC ELQNRIKETL SWVKNTMAEL VVPIALLPDN ILSQIRKCKL
2770 2780 2790 2800 2810 2820
IHDGILGNQQ AVELLVEEVR GITPSLAPCE GDGLNALLED LQSQHQALLL KSTERSQQLE
2830 2840 2850 2860 2870 2880
LKLEEKSKLF AIIGKVQLTL EESETLMSPT GDRASTEAEL ERRLAILKAS QQQLQDTESA
2890 2900 2910 2920 2930 2940
LSAHLQELTN AYKDANVFER LFLDDQLKNL KARTNRTQRF LQNNGSELKQ KMESYREFHD
2950 2960 2970 2980 2990 3000
KAAVLQKEAE CILHGGLLPL RQELEQDAKE QLGNLRDKLA AIRGSLSQVL TSEEVFDTIG
3010 3020 3030 3040 3050 3060
LSWDGSLLAR LQTQVLERER EVEGKIKQLD TFLIARDRHQ ASISKIRAVD LQIKKGAESL
3070 3080 3090 3100 3110 3120
LKVPSMSPES TLLNAQTLIQ KIEKSKRLRD EIIRKLSKNE AFDDSFKESE MQRLKLCAEE
3130 3140 3150 3160 3170 3180
NSRLQEALQN MLLELQPREM GEKEFREKLE NALHVLKQIQ SRLQQPLCVN LGVQHIQHEK
3190 3200 3210 3220 3230 3240
ETWEAFGEQV EAEMCGLRAV RITEEQREEN DSGTGGMEAK LRDIEGLHME LSKSISLRAD
3250 3260 3270 3280 3290 3300
VLNDAYDSAN RYDELVAGAL RIITSLEATL LSYRVDLHNP QKTLELAHLK QEELQSSVAD
3310 3320 3330 3340 3350 3360
LRSLTETLGA ISSPEAKEQL RCTLEVLAAK NSALKAGLEA QEAEEERCLE NYKCFRKMKE
3370 3380 3390 3400 3410 3420
EICSRLRKME MDLGQSIFPL PRSYKEALAR LEQSKALTSN LLSTKEDLVK LRQLLRHLRC
3430 3440 3450 3460 3470 3480
RSTENDATCA LGVASALWEK WLSLLEAARE WQQWGGELKR EWKFISEEIE REAIILETLQ
3490 3500 3510 3520 3530 3540
EDLPEISKTN AAPTEELWQL LDSLCQHQES VEKQQLLLAL LLQRVRSIQN IPEGTETGET
3550 3560 3570 3580 3590 3600
IPALQEIGSM QERCDRLLHT TRKNKDLVQA EIQAQQSFLK EIKDVKRVFE QISTSFPNLA
3610 3620 3630 3640 3650 3660
PEGHPERAEQ FEELRSILQK GKLSFENIME KLRIKYSEMY SIVPAEIGSQ VEECRSALED
3670 3680 3690 3700 3710 3720
AEEKMSSEVS KSSPSSIMRR KIERINNGLH CVEKMLQQKS RNIEEAHEIQ KKIWDELDLW
3730 3740 3750 3760 3770 3780
HSKLNELDSE VQDFVEQDPG QAQEWMDNLM APFQQHQQVS QRAESRTSQL NKATIKMEEY
3790 3800 3810 3820 3830 3840
NDLLKSTEVW IEKTSCLLAN PACYDSSRTL SHRASTLQMA LEDSEQKHSL LHSIFTDLED
3850 3860 3870 3880 3890 3900
LSIIFETDDL IQTIHELSDQ VAALQQQIME ALPHVQQVAD DVVAIESEVK AMEKKVAKIK
3910 3920 3930 3940 3950 3960
AILLSKEIFD FPPEEHLKHG EVILENIHPM KKTIAEIMTY QVELRLPQTG TKPLPVFQRT
3970 3980 3990 4000 4010 4020
SQLLQDVKLL ENVTQEQNEL LKVVIKQTAE CDEEIDSLKQ MLTNYSAEIS PEHVSQNQVA
4030 4040 4050 4060 4070 4080
DLPSLQGEME RLEKQILNLN QKKEDLLVDL KTAVLNLHEH LKQEQQEVGD KPSAGASECT
4090 4100 4110 4120 4130 4140
VAERDASERK LSRTNSMSFL PVVKEEAEES SVKSEDGRRR TEPPSASWSF LGKHSKDLEG
4150 4160 4170 4180 4190 4200
DGASSSSSAT IVQDADGRIS TCDSSMVHII APDSGSTEEG PAPSPRLSQT DEGATPPIEA
4210 4220 4230 4240 4250 4260
ALLDFPREQG AFESTVERSR PRPADILRVC KTQVAKLELW LQQANVAFEP ETVDADMQQV
4270 4280 4290 4300 4310 4320
VEEELAGCQA MLTEIEYKVA SLLETCKDQG LGDCGTTQQE AEALSWKLKT VKCNLEKVQM
4330 4340 4350 4360 4370 4380
VLQEKFSEDQ HPSTLKKPSE PHDVDQPAGL SELDSVLTER PQFSRQKDAP QPQILELKPS
4390 4400 4410 4420 4430 4440
EQKDLIKFTE LNAKKTWLQG HQENEDANRQ SASSSKVPSP GNAASDSTLP LQAQSGDKWQ
4450 4460 4470 4480 4490 4500
YLHHELTSRP NPSVPQLVEP QVALTTSTLP SVSVYNFRCP TADELQAYTT QLEELRQEAN
4510 4520 4530 4540 4550 4560
TIQTQGSMTE ETYISLDKRL FELFLSLSRC LGSVEGLLQR PGLLREDACA QQVFFQKLAL
4570 4580 4590 4600 4610 4620
ELKKLYLALG DKKDDFLKAV TWPGKEATLL PECIDALTVS LESVQSRAAW RDASLKAGLE
4630 4640 4650 4660 4670 4680
HSRSYQNEVK RLYSQLIKKK TALQQSLNEI SGQSISKQLQ KADVHTAELQ NSEKQVAKLR
4690 4700 4710 4720 4730 4740
DEGERLRFPH GLLQDVYKLE DVLDSMWGIL RARYLELSSP FLSKSLQTLL QGMAELVSIG
4750 4760 4770 4780 4790 4800
KGKLAADPLQ HAKSKAALQA QLQDHKAFFQ KLVADMLLIQ TYSATMFPPS LQKGEGFGAE
4810 4820 4830 4840 4850 4860
QVAEVRALEE EACLRGAQLQ SMLQKWEEFD DNYASLEKDL EALISSLPSV SLVEETEERL
4870 4880 4890 4900 4910 4920
LERISFYQQI KRNIDGKHAR LCQTLNEGRQ LAASVSCPEP EGQIARLEEQ WLSLNKRIDQ
4930 4940 4950 4960 4970 4980
ELHRLQTLLK HLLSYSRDSD ELTRWLETSQ QTLNYWKEQS LNVSQDLNTI RSNIDRFFKF
4990 5000 5010 5020 5030 5040
SKEVDERSSL KSAVMSTGNQ LLHLKEADTA TLRASLAQFE QKWTVLITQL PDIQEKLHQL
5050 5060 5070 5080 5090 5100
QMEKLPSREA ISEMISWMNA VEPQAAGKDT ELSKSSASQV KHLLQKLKEF RMEMDYKQWV
5110 5120 5130 5140 5150 5160
VDFVNQSLLQ LSTCDVESKR YERTEFAEHL GEMNRQWQRV HGTLNRKIQH LEQLLESITE
5170 5180 5190 5200 5210 5220
NENKVQNLNS WLEAQEERLK MLQKPESAVS MEKLLLDCQD IENQLALKSK ALDELRQSSL
5230 5240 5250 5260 5270 5280
TMDGGDVPLL EDMASGIVEL FQKKNNVTSQ VHQLRASVQS VLQEWKACDK LYDEATMRTT
5290 5300 5310 5320 5330 5340
QLTYSMEHSK PAVLSLQALA CQVQNLEALQ DEAENGERSW EKLQEVIGRL KASCPSMAGI
5350 5360 5370 5380 5390 5400
IEEKCQDAHS RWTQVNQDLA DQLQEARGQL QLWKAPHNAH AEAAAWLQQQ EAKFQQLANT
5410 5420 5430 5440 5450 5460
NLSGDNLADI LPRALKDIKG LQSDLQKTKE AFLENSTLSD QLPQPEERST PGLHSGQRHS
5470 5480 5490 5500 5510 5520
LQTAAYLEKM LLAKSNEFEI VLAQFKDFTD RLAYSKDLIV HKEENLNKLY HEEKEEVPDL
5530 5540 5550 5560 5570 5580
FLNHVLALTA QSPDIERLNE ESLRLPLSDV TIKTLQSLNR QWIRATATAL DHYSELQGNG
5590 5600 5610 5620 5630 5640
LNEKFLHYCE RWIQVLEKIQ ESLSVEVAHS LPALLEQQKT YEILEAEVST NQAVADAYVT
5650 5660 5670 5680 5690 5700
QSLQLLDTAE IEKRPEFVSE FSKLSDQWQR AARGVRQRKC DISRLVTQWR FFTTSVEDLL
5710 5720 5730 5740 5750 5760
RFLADTSQLL SAVKEQDCYS LCQTRRLVHE LKSKEIHLQR WRTTYALALE AGEKLRNTPS
5770 5780 5790 5800 5810 5820
PETREFVDGQ ISRLQESWKD TELSLGEVIS RLQSTAETWD QCKKKIKKLK KRLQALKAQS
5830 5840 5850 5860 5870 5880
EDPLPELHEA LHEEKELIKE VEKSLANWTH SLKELQTMKA DLSQHILAED VTVLKEQIQL
5890 5900 5910 5920 5930 5940
LHRQWEDLCL RVAIRKQEIE DRLNSWIVFN EKNKELCAWL VQMENKVLQT ADVSIEEMIE
5950 5960 5970 5980 5990 6000
KLQKDCMEEI SLFTENKLQL KQMGDQLIKA SSKAKAAELE EKLSKINDRW QHLFDVIGSR
6010 6020 6030 6040 6050 6060
VKKLKETFAF IQQLDKNMSN LRTWLARIES ELSKPVVYDV CDNQEIQKRL AEQQDLQRDI
6070 6080 6090 6100 6110 6120
EQHSAGVESV FNICDVLLHD SDACANETEC DSIQQTTRSL DRRWRNICAM SMERRMKIEE
6130 6140 6150 6160 6170 6180
TWRLWQKFLD DYSRFEDWLK SAERTAACPN SSEVLYTNAK EELKRFEAFQ RQIHERLTQL
6190 6200 6210 6220 6230 6240
ELINKQYRRL ARENRTDTAS KLKQMVHEGN QRWDNLQKRV TAILRRLRYF TNQREEFEGT
6250 6260 6270 6280 6290 6300
RESILVWLTE MDLQLTNVEH FSESDAEDKM RQLNGFQQEI TLNTNKIDQL IVFGEQLIQK
6310 6320 6330 6340 6350 6360
SEPLDAVLIE DELEELHRYC QEVFGRVSRF HRRLTSHTPG LDDEKEASEN ETDIEDPREI
6370 6380 6390 6400 6410 6420
QADSWRKRRE SEEPTSPQSL CHLVPPALGH ERSGCETPVS VDSIPLEWDH TGDVGGSSSH
6430 6440 6450 6460 6470 6480
EDDEEGPFYS ALSGKSISEG HPWHVPDSPS HSKHHYKHME GDRTEAPVPT DASTPFKSDY
6490 6500 6510 6520 6530 6540
VKLLLRQGTD DSKEGLKEAQ QEDEQLATLT GQQPGAFDRW ELIQAQELHS KLRLKQTVQQ
6550 6560 6570 6580 6590 6600
LKSDIGSIAA WLGKTEAELE ALKLAEPPSD IQEIALRVKR LQEILKAFDT YKALMVSVNV
6610 6620 6630 6640 6650 6660
SHKEYLPSQS PEATELQNRL HQLSLSWDSV QGVLDSWRGD LRQSLMQCQD FHQLSQDLLL
6670 6680 6690 6700 6710 6720
WLATAESRRQ KAHVTSPEAD RQVLLECQKD LMRLEKELVA RQPQVSSLRE ISSSLLVKGQ
6730 6740 6750 6760 6770 6780
GEDYIEAEEK VHVIEKKLKQ LQEQVAQDLM SLQRSLDPDA SLTSFDEVDS GEQLPAAFAK
6790 6800 6810 6820 6830 6840
SPRPRWTFLE EEEEEEETDS RMPHLDSPGS SQPRRSFLSR VIRAALPLQL LLLLLLLLAC
6850 6860 6870
LLPASEDDYS CTQANNFARS FYPMLRYTNG PPPT
Isoforms
- Isoform 2 of Nesprin-2 - Isoform 3 of Nesprin-2Sequence View
10 20 30 40 50 60
MAASPVLPTE DGEGFLGIDD LHFSLQAEQE DTQKKTFTCW INSQLAKHTP PSVVSDLFAD
70 80 90 100 110 120
IKKGHVLLDL LEVLSGQQLP RDKGSNTFQC RINIEHALTF LKNRSIKLIN IHVADIVEGN
130 140 150 160 170 180
PSIILGLIWT IILHFHIEKL AQTLSCDYNQ PSPEVVSVAA SSPTSSPPTK KCSKAQAQAR
190 200 210 220 230 240
WQWSAKKALL QWAQEQCARS ESVNVTDFKS SWRNGMAFLA VIHALRPDLI DMDSMRHRSN
250 260 270 280 290 300
KDNLKEAFRI AEHELKIPKL LEPEDVDVVN PDEKSIMTYV AQFLKYSKDA PGPGDSTQAK
310 320 330 340 350 360
VRDALVWLTL QEKRFQKMLK DSASETYCNK YHSLLSFMES LNEEKESFID VLSLKGRMGE
370 380 390 400 410 420
LNEDESRLRQ GWTSLMHQVA AWRAQLDDAL PSPLKETEAW LKDIEGVVQE GVPTSQSYSE
430 440 450 460 470 480
ARTLIQGKLS SFKSLMGSFD YHSDVLMAFQ SNAEKSLPAV PPVKLEEMTR RINNVLGKNF
490 500 510 520 530 540
IPLLEFHDSK CSVLALLDEA KAKLDVWNGT YESKESVEVL LEDWHKFTGE KKFLIQLDAS
550 560 570 580 590 600
FQKCEEMYKN SARECESIRE EYMMLEKNVH SCRQYIHNTK ATLQRALMSW ATFEEDLALL
610 620 630 640 650 660
KASFDLTKKE QIKEVPVETL LQWNTKHTSL NEVGSFLIGV SSREVAASIS KELRRLNKRW
670 680 690 700 710 720
RKFITKTPLL KLPLVKIQDQ PPGNSSGTSL SKESAMAAEP GGSRGEDVKA AEKQEVEDEE
730 740 750 760 770 780
SAGQLKVNEE VEGLIKQVTI WESQTKSILD LLQHGDHADG SSADTLQHLI AKGSVYEELL
790 800 810 820 830 840
ARTEDTLQMD VQSPSNLEPF QNVLRAGLQA KIQEAKQGVQ ITMVELSAVL KNLSDEPLEL
850 860 870 880 890 900
DLGLKVEEAQ KELEVSILRA EQLLGQRERP GGFLLKYKEA LEILNTNSLA KYLRAVEELK
910 920 930 940 950 960
RTVPGGAKLQ LEEQSRVASA KWEPLRHEIS LYLQQLKIAI EEEKLRDNIA RLEKQINKEK
970 980 990 1000 1010 1020
KLIRRGRTRG LRKEHEACLS PESIKCQLEH HVGVLRVLCE ELTSPEDQQE LKRALRDYEQ
1030 1040 1050 1060 1070 1080
KIARLLKCAS EIHTTLQSSQ GGALEERSAL ITTENGRRDA DGEVPLEIPD NQLSTEKAME
1090 1100 1110 1120 1130 1140
PIKNFSQTSE LKPQQEESIM EKEGKDCSAS LSDLQERYDT QRGLLEQHLQ DSKSRVTSDF
1150 1160 1170 1180 1190 1200
ASEQERSSAC LQSKLAELQV LLADTDAHWE KFEITSLNLR RLMSDAEKPV LNQERDLLKG
1210 1220 1230 1240 1250 1260
NEQVLHGLLN TRMESLEMAL QIVLPLEKEC SLLCASDLPL CTVAVQDLHP VEIDGVYQNL
1270 1280 1290 1300 1310 1320
RDIRDSIAKQ IRVCTSLEEP SNSVPRELHT LDQCAIQDIV LKCRLQLETM NQKVEMREDA
1330 1340 1350 1360 1370 1380
LDALEGFLAS LRAAKLSAEL PADRPAPKAP EVLSEDILLM KEKAGPLDER LRTLGINIKD
1390 1400 1410 1420 1430 1440
AEGGENTTCE RLVGALSVNL VAMDGQSKEE GPPEDKKLLE ACSSKNLELF KNIQDLQNQI
1450 1460 1470 1480 1490 1500
SKIGLKDPTA PAVKHRKKSL LRLDKDLDGL EEEKVRIQKI AGSLPRFKDG SEKNVIQQCE
1510 1520 1530 1540 1550 1560
DTAALWESTK ASVTESLEQC GSALELLRQY QNIKNNLTAL IQKEEGIISQ QASYMGKDNL
1570 1580 1590 1600 1610 1620
KKKIAEIETV KEEFSDHLEV VDKINQICKN LQYHLNKMKT FEDPPFEKEA NAIVDRWLDI
1630 1640 1650 1660 1670 1680
NEKTEEYGEN LGRALALWDK LFIIKNNIDE WTEQILGKAE SHELTEEDRG RLKEELKVLE
1690 1700 1710 1720 1730 1740
EQSAEFSRRV ADIQSLLQSN EKPLELQVME SSVLSKMKDV KTHVAGGSNS YAPSGSTAEL
1750 1760 1770 1780 1790 1800
REDLDQAKTQ MGMTESLLNA LSPSDSLEIF TKLEEIQQQI FQQKHSMTVL ENQIGCLTPE
1810 1820 1830 1840 1850 1860
LSELKRQYAS VSNLFNTKKN ALQDHFATFL NEQCKNFNDW FSNVKTNLQE CFEPPETKLS
1870 1880 1890 1900 1910 1920
LEQRLQKLSD FLTLGGGNSK IQQVETVLQH VKMLLPKAHV KELDSWLRSQ ELELENMESI
1930 1940 1950 1960 1970 1980
CQARAGELNN SFQQLLRLED DCRSLSKWLT NQEENWGKME VSGERMDLFS QALTRKREQF
1990 2000 2010 2020 2030 2040
ETVAQLSDSL KEHGLTEGEE TIKESTHLID RYQALWRQLH EIEEEDKLPA AEDQSFNDLA
2050 2060 2070 2080 2090 2100
DDVIHWIKEI KESLMALNSS EGKMPLEERI QKIKEIIALK PEGDAKIQMV MRQAEHCEAP
2110 2120 2130 2140 2150 2160
LAQETFTDLS NQWDSTLHLA NTYLSHQEKL VLEGEKYLQS KEDLRLMLTE LKKQQEAGFA
2170 2180 2190 2200 2210 2220
LQPGLPEKQA QLKIYKKFLQ KAQDLTSLLE ELKSQGNYLL ECTKNPSFSE EPWLEVKHLH
2230 2240 2250 2260 2270 2280
ESLLQQLQDS VQKLEGHVQE HSSYQVCLTD LSSTLDDISK EYFSLCDGSK DQIMAKERMQ
2290 2300 2310 2320 2330 2340
KLQELESRLR FQGGALKKAS ALAKSIKQNT SSVGQKIIKD DIRSLKYKQK DLENRIESAK
2350 2360 2370 2380 2390 2400
QETENGLNSI LKSKSSTEKH VKFSLPVEEM PATSEVPKPT RESAAVGESG GARETNTNSA
2410 2420 2430 2440 2450 2460
VEMILSKQLS LNVQESMQNA QDEREVNELQ NQPLELDIML RNEQLKGMEE LSTHLEARRA
2470 2480 2490 2500 2510 2520
AIELLEQSQH LNQTEEQALV LPAARPSVCH LGSLQQELHT LKKTKERQYG LLSGFQDQLV
2530 2540 2550 2560 2570 2580
MAEASLNTSL AEVESLKIGS LDSATYLGKI KKFLGSVENQ QGSLSKLRTE WAHLSSLLAA
2590 2600 2610 2620 2630 2640
ADQKLVESQM KHLEHGWELV EQLAHRKCFQ QATEHSELTC LLEKLQDLKV SLHQQQQRLT
2650 2660 2670 2680 2690 2700
LSLNSPGQQA AIVDMVTPAA ELQAIKCEFS GLKWQAELHM KRLWGEKDKK TLEDAINNLN
2710 2720 2730 2740 2750 2760
KQMEALEPLN REVENRIKKC ELQNRIKETL SWVKNTMAEL VVPIALLPDN ILSQIRKCKL
2770 2780 2790 2800 2810 2820
IHDGILGNQQ AVELLVEEVR GITPSLAPCE GDGLNALLED LQSQHQALLL KSTERSQQLE
2830 2840 2850 2860 2870 2880
LKLEEKSKLF AIIGKVQLTL EESETLMSPT GDRASTEAEL ERRLAILKAS QQQLQDTESA
2890 2900 2910 2920 2930 2940
LSAHLQELTN AYKDANVFER LFLDDQLKNL KARTNRTQRF LQNNGSELKQ KMESYREFHD
2950 2960 2970 2980 2990 3000
KAAVLQKEAE CILHGGLLPL RQELEQDAKE QLGNLRDKLA AIRGSLSQVL TSEEVFDTIG
3010 3020 3030 3040 3050 3060
LSWDGSLLAR LQTQVLERER EVEGKIKQLD TFLIARDRHQ ASISKIRAVD LQIKKGAESL
3070 3080 3090 3100 3110 3120
LKVPSMSPES TLLNAQTLIQ KIEKSKRLRD EIIRKLSKNE AFDDSFKESE MQRLKLCAEE
3130 3140 3150 3160 3170 3180
NSRLQEALQN MLLELQPREM GEKEFREKLE NALHVLKQIQ SRLQQPLCVN LGVQHIQHEK
3190 3200 3210 3220 3230 3240
ETWEAFGEQV EAEMCGLRAV RITEEQREEN DSGTGGMEAK LRDIEGLHME LSKSISLRAD
3250 3260 3270 3280 3290 3300
VLNDAYDSAN RYDELVAGAL RIITSLEATL LSYRVDLHNP QKTLELAHLK QEELQSSVAD
3310 3320 3330 3340 3350 3360
LRSLTETLGA ISSPEAKEQL RCTLEVLAAK NSALKAGLEA QEAEEERCLE NYKCFRKMKE
3370 3380 3390 3400 3410 3420
EICSRLRKME MDLGQSIFPL PRSYKEALAR LEQSKALTSN LLSTKEDLVK LRQLLRHLRC
3430 3440 3450 3460 3470 3480
RSTENDATCA LGVASALWEK WLSLLEAARE WQQWGGELKR EWKFISEEIE REAIILETLQ
3490 3500 3510 3520 3530 3540
EDLPEISKTN AAPTEELWQL LDSLCQHQES VEKQQLLLAL LLQRVRSIQN IPEGTETGET
3550 3560 3570 3580 3590 3600
IPALQEIGSM QERCDRLLHT TRKNKDLVQA EIQAQQSFLK EIKDVKRVFE QISTSFPNLA
3610 3620 3630 3640 3650 3660
PEGHPERAEQ FEELRSILQK GKLSFENIME KLRIKYSEMY SIVPAEIGSQ VEECRSALED
3670 3680 3690 3700 3710 3720
AEEKMSSEVS KSSPSSIMRR KIERINNGLH CVEKMLQQKS RNIEEAHEIQ KKIWDELDLW
3730 3740 3750 3760 3770 3780
HSKLNELDSE VQDFVEQDPG QAQEWMDNLM APFQQHQQVS QRAESRTSQL NKATIKMEEY
3790 3800 3810 3820 3830 3840
NDLLKSTEVW IEKTSCLLAN PACYDSSRTL SHRASTLQMA LEDSEQKHSL LHSIFTDLED
3850 3860 3870 3880 3890 3900
LSIIFETDDL IQTIHELSDQ VAALQQQIME ALPHVQQVAD DVVAIESEVK AMEKKVAKIK
3910 3920 3930 3940 3950 3960
AILLSKEIFD FPPEEHLKHG EVILENIHPM KKTIAEIMTY QVELRLPQTG TKPLPVFQRT
3970 3980 3990 4000 4010 4020
SQLLQDVKLL ENVTQEQNEL LKVVIKQTAE CDEEIDSLKQ MLTNYSAEIS PEHVSQNQVA
4030 4040 4050 4060 4070 4080
DLPSLQGEME RLEKQILNLN QKKEDLLVDL KTAVLNLHEH LKQEQQEVGD KPSAGASECT
4090 4100 4110 4120 4130 4140
VAERDASERK LSRTNSMSFL PVVKEEAEES SVKSEDGRRR TEPPSASWSF LGKHSKDLEG
4150 4160 4170 4180 4190 4200
DGASSSSSAT IVQDADGRIS TCDSSMVHII APDSGSTEEG PAPSPRLSQT DEGATPPIEA
4210 4220 4230 4240 4250 4260
ALLDFPREQG AFESTVERSR PRPADILRVC KTQVAKLELW LQQANVAFEP ETVDADMQQV
4270 4280 4290 4300 4310 4320
VEEELAGCQA MLTEIEYKVA SLLETCKDQG LGDCGTTQQE AEALSWKLKT VKCNLEKVQM
4330 4340 4350 4360 4370 4380
VLQEKFSEDQ HPSTLKKPSE PHDVDQPAGL SELDSVLTER PQFSRQKDAP QPQILELKPS
4390 4400 4410 4420 4430 4440
EQKDLIKFTE LNAKKTWLQG HQENEDANRQ SASSSKVPSP GNAASDSTLP LQAQSGDKWQ
4450 4460 4470 4480 4490 4500
YLHHELTSRP NPSVPQLVEP QVALTTSTLP SVSVYNFRCP TADELQAYTT QLEELRQEAN
4510 4520 4530 4540 4550 4560
TIQTQGSMTE ETYISLDKRL FELFLSLSRC LGSVEGLLQR PGLLREDACA QQVFFQKLAL
4570 4580 4590 4600 4610 4620
ELKKLYLALG DKKDDFLKAV TWPGKEATLL PECIDALTVS LESVQSRAAW RDASLKAGLE
4630 4640 4650 4660 4670 4680
HSRSYQNEVK RLYSQLIKKK TALQQSLNEI SGQSISKQLQ KADVHTAELQ NSEKQVAKLR
4690 4700 4710 4720 4730 4740
DEGERLRFPH GLLQDVYKLE DVLDSMWGIL RARYLELSSP FLSKSLQTLL QGMAELVSIG
4750 4760 4770 4780 4790 4800
KGKLAADPLQ HAKSKAALQA QLQDHKAFFQ KLVADMLLIQ TYSATMFPPS LQKGEGFGAE
4810 4820 4830 4840 4850 4860
QVAEVRALEE EACLRGAQLQ SMLQKWEEFD DNYASLEKDL EALISSLPSV SLVEETEERL
4870 4880 4890 4900 4910 4920
LERISFYQQI KRNIDGKHAR LCQTLNEGRQ LAASVSCPEP EGQIARLEEQ WLSLNKRIDQ
4930 4940 4950 4960 4970 4980
ELHRLQTLLK HLLSYSRDSD ELTRWLETSQ QTLNYWKEQS LNVSQDLNTI RSNIDRFFKF
4990 5000 5010 5020 5030 5040
SKEVDERSSL KSAVMSTGNQ LLHLKEADTA TLRASLAQFE QKWTVLITQL PDIQEKLHQL
5050 5060 5070 5080 5090 5100
QMEKLPSREA ISEMISWMNA VEPQAAGKDT ELSKSSASQV KHLLQKLKEF RMEMDYKQWV
5110 5120 5130 5140 5150 5160
VDFVNQSLLQ LSTCDVESKR YERTEFAEHL GEMNRQWQRV HGTLNRKIQH LEQLLESITE
5170 5180 5190 5200 5210 5220
NENKVQNLNS WLEAQEERLK MLQKPESAVS MEKLLLDCQD IENQLALKSK ALDELRQSSL
5230 5240 5250 5260 5270 5280
TMDGGDVPLL EDMASGIVEL FQKKNNVTSQ VHQLRASVQS VLQEWKACDK LYDEATMRTT
5290 5300 5310 5320 5330 5340
QLTYSMEHSK PAVLSLQALA CQVQNLEALQ DEAENGERSW EKLQEVIGRL KASCPSMAGI
5350 5360 5370 5380 5390 5400
IEEKCQDAHS RWTQVNQDLA DQLQEARGQL QLWKAPHNAH AEAAAWLQQQ EAKFQQLANT
5410 5420 5430 5440 5450 5460
NLSGDNLADI LPRALKDIKG LQSDLQKTKE AFLENSTLSD QLPQPEERST PGLHSGQRHS
5470 5480 5490 5500 5510 5520
LQTAAYLEKM LLAKSNEFEI VLAQFKDFTD RLAYSKDLIV HKEENLNKLY HEEKEEVPDL
5530 5540 5550 5560 5570 5580
FLNHVLALTA QSPDIERLNE ESLRLPLSDV TIKTLQSLNR QWIRATATAL DHYSELQGNG
5590 5600 5610 5620 5630 5640
LNEKFLHYCE RWIQVLEKIQ ESLSVEVAHS LPALLEQQKT YEILEAEVST NQAVADAYVT
5650 5660 5670 5680 5690 5700
QSLQLLDTAE IEKRPEFVSE FSKLSDQWQR AARGVRQRKC DISRLVTQWR FFTTSVEDLL
5710 5720 5730 5740 5750 5760
RFLADTSQLL SAVKEQDCYS LCQTRRLVHE LKSKEIHLQR WRTTYALALE AGEKLRNTPS
5770 5780 5790 5800 5810 5820
PETREFVDGQ ISRLQESWKD TELSLGEVIS RLQSTAETWD QCKKKIKKLK KRLQALKAQS
5830 5840 5850 5860 5870 5880
EDPLPELHEA LHEEKELIKE VEKSLANWTH SLKELQTMKA DLSQHILAED VTVLKEQIQL
5890 5900 5910 5920 5930 5940
LHRQWEDLCL RVAIRKQEIE DRLNSWIVFN EKNKELCAWL VQMENKVLQT ADVSIEEMIE
5950 5960 5970 5980 5990 6000
KLQKDCMEEI SLFTENKLQL KQMGDQLIKA SSKAKAAELE EKLSKINDRW QHLFDVIGSR
6010 6020 6030 6040 6050 6060
VKKLKETFAF IQQLDKNMSN LRTWLARIES ELSKPVVYDV CDNQEIQKRL AEQQDLQRDI
6070 6080 6090 6100 6110 6120
EQHSAGVESV FNICDVLLHD SDACANETEC DSIQQTTRSL DRRWRNICAM SMERRMKIEE
6130 6140 6150 6160 6170 6180
TWRLWQKFLD DYSRFEDWLK SAERTAACPN SSEVLYTNAK EELKRFEAFQ RQIHERLTQL
6190 6200 6210 6220 6230 6240
ELINKQYRRL ARENRTDTAS KLKQMVHEGN QRWDNLQKRV TAILRRLRYF TNQREEFEGT
6250 6260 6270 6280 6290 6300
RESILVWLTE MDLQLTNVEH FSESDAEDKM RQLNGFQQEI TLNTNKIDQL IVFGEQLIQK
6310 6320 6330 6340 6350 6360
SEPLDAVLIE DELEELHRYC QEVFGRVSRF HRRLTSHTPG LDDEKEASEN ETDIEDPREI
6370 6380 6390 6400 6410 6420
QADSWRKRRE SEEPTSPQSL CHLVPPALGH ERSGCETPVS VDSIPLEWDH TGDVGGSSSH
6430 6440 6450 6460 6470 6480
EDDEEGPFYS ALSGKSISEG HPWHVPDSPS HSKHHYKHME GDRTEAPVPT DASTPFKSDY
6490 6500 6510 6520 6530 6540
VKLLLRQGTD DSKEGLKEAQ QEDEQLATLT GQQPGAFDRW ELIQAQELHS KLRLKQTVQQ
6550 6560 6570 6580 6590 6600
LKSDIGSIAA WLGKTEAELE ALKLAEPPSD IQEIALRVKR LQEILKAFDT YKALMVSVNV
6610 6620 6630 6640 6650 6660
SHKEYLPSQS PEATELQNRL HQLSLSWDSV QGVLDSWRGD LRQSLMQCQD FHQLSQDLLL
6670 6680 6690 6700 6710 6720
WLATAESRRQ KAHVTSPEAD RQVLLECQKD LMRLEKELVA RQPQVSSLRE ISSSLLVKGQ
6730 6740 6750 6760 6770 6780
GEDYIEAEEK VHVIEKKLKQ LQEQVAQDLM SLQRSLDPDA SLTSFDEVDS GEQLPAAFAK
6790 6800 6810 6820 6830 6840
SPRPRWTFLE EEEEEEETDS RMPHLDSPGS SQPRRSFLSR VIRAALPLQL LLLLLLLLAC
6850 6860 6870
LLPASEDDYS CTQANNFARS FYPMLRYTNG PPPT
10 20 30 40 50 60
MAASPVLPTE DGEGFLGIDD LHFSLQAEQE DTQKKTFTCW INSQLAKHTP PSVVSDLFAD
70 80 90 100 110 120
IKKGHVLLDL LEVLSGQQLP RDKGSNTFQC RINIEHALTF LKNRSIKLIN IHVADIVEGN
130 140 150 160 170 180
PSIILGLIWT IILHFHIEKL AQTLSCDYNQ PSPEVVSVAA SSPTSSPPTK KCSKAQAQAR
190 200 210 220 230 240
WQWSAKKALL QWAQEQCARS ESVNVTDFKS SWRNGMAFLA VIHALRPDLI DMDSMRHRSN
250 260 270 280 290 300
KDNLKEAFRI AEHELKIPKL LEPEDVDVVN PDEKSIMTYV AQFLKYSKDA PGPGDSTQAK
310 320 330 340 350 360
VRDALVWLTL QEKRFQKMLK DSASETYCNK YHSLLSFMES LNEEKESFID VLSLKGRMGE
370 380 390 400 410 420
LNEDESRLRQ GWTSLMHQVA AWRAQLDDAL PSPLKETEAW LKDIEGVVQE GVPTSQSYSE
430 440 450 460 470 480
ARTLIQGKLS SFKSLMGSFD YHSDVLMAFQ SNAEKSLPAV PPVKLEEMTR RINNVLGKNF
490 500 510 520 530 540
IPLLEFHDSK CSVLALLDEA KAKLDVWNGT YESKESVEVL LEDWHKFTGE KKFLIQLDAS
550 560 570 580 590 600
FQKCEEMYKN SARECESIRE EYMMLEKNVH SCRQYIHNTK ATLQRALMSW ATFEEDLALL
610 620 630 640 650 660
KASFDLTKKE QIKEVPVETL LQWNTKHTSL NEVGSFLIGV SSREVAASIS KELRRLNKRW
670 680 690 700 710 720
RKFITKTPLL KLPLVKIQDQ PPGNSSGTSL SKESAMAAEP GGSRGEDVKA AEKQEVEDEE
730 740 750 760 770 780
SAGQLKVNEE VEGLIKQVTI WESQTKSILD LLQHGDHADG SSADTLQHLI AKGSVYEELL
790 800 810 820 830 840
ARTEDTLQMD VQSPSNLEPF QNVLRAGLQA KIQEAKQGVQ ITMVELSAVL KNLSDEPLEL
850 860 870 880 890 900
DLGLKVEEAQ KELEVSILRA EQLLGQRERP GGFLLKYKEA LEILNTNSLA KYLRAVEELK
910 920 930 940 950 960
RTVPGGAKLQ LEEQSRVASA KWEPLRHEIS LYLQQLKIAI EEEKLRDNIA RLEKQINKEK
970 980 990 1000 1010 1020
KLIRRGRTRG LRKEHEACLS PESIKCQLEH HVGVLRVLCE ELTSPEDQQE LKRALRDYEQ
1030 1040 1050 1060 1070 1080
KIARLLKCAS EIHTTLQSSQ GGALEERSAL ITTENGRRDA DGEVPLEIPD NQLSTEKAME
1090 1100 1110 1120 1130 1140
PIKNFSQTSE LKPQQEESIM EKEGKDCSAS LSDLQERYDT QRGLLEQHLQ DSKSRVTSDF
1150 1160 1170 1180 1190 1200
ASEQERSSAC LQSKLAELQV LLADTDAHWE KFEITSLNLR RLMSDAEKPV LNQERDLLKG
1210 1220 1230 1240 1250 1260
NEQVLHGLLN TRMESLEMAL QIVLPLEKEC SLLCASDLPL CTVAVQDLHP VEIDGVYQNL
1270 1280 1290 1300 1310 1320
RDIRDSIAKQ IRVCTSLEEP SNSVPRELHT LDQCAIQDIV LKCRLQLETM NQKVEMREDA
1330 1340 1350 1360 1370 1380
LDALEGFLAS LRAAKLSAEL PADRPAPKAP EVLSEDILLM KEKAGPLDER LRTLGINIKD
1390 1400 1410 1420 1430 1440
AEGGENTTCE RLVGALSVNL VAMDGQSKEE GPPEDKKLLE ACSSKNLELF KNIQDLQNQI
1450 1460 1470 1480 1490 1500
SKIGLKDPTA PAVKHRKKSL LRLDKDLDGL EEEKVRIQKI AGSLPRFKDG SEKNVIQQCE
1510 1520 1530 1540 1550 1560
DTAALWESTK ASVTESLEQC GSALELLRQY QNIKNNLTAL IQKEEGIISQ QASYMGKDNL
1570 1580 1590 1600 1610 1620
KKKIAEIETV KEEFSDHLEV VDKINQICKN LQYHLNKMKT FEDPPFEKEA NAIVDRWLDI
1630 1640 1650 1660 1670 1680
NEKTEEYGEN LGRALALWDK LFIIKNNIDE WTEQILGKAE SHELTEEDRG RLKEELKVLE
1690 1700 1710 1720 1730 1740
EQSAEFSRRV ADIQSLLQSN EKPLELQVME SSVLSKMKDV KTHVAGGSNS YAPSGSTAEL
1750 1760 1770 1780 1790 1800
REDLDQAKTQ MGMTESLLNA LSPSDSLEIF TKLEEIQQQI FQQKHSMTVL ENQIGCLTPE
1810 1820 1830 1840 1850 1860
LSELKRQYAS VSNLFNTKKN ALQDHFATFL NEQCKNFNDW FSNVKTNLQE CFEPPETKLS
1870 1880 1890 1900 1910 1920
LEQRLQKLSD FLTLGGGNSK IQQVETVLQH VKMLLPKAHV KELDSWLRSQ ELELENMESI
1930 1940 1950 1960 1970 1980
CQARAGELNN SFQQLLRLED DCRSLSKWLT NQEENWGKME VSGERMDLFS QALTRKREQF
1990 2000 2010 2020 2030 2040
ETVAQLSDSL KEHGLTEGEE TIKESTHLID RYQALWRQLH EIEEEDKLPA AEDQSFNDLA
2050 2060 2070 2080 2090 2100
DDVIHWIKEI KESLMALNSS EGKMPLEERI QKIKEIIALK PEGDAKIQMV MRQAEHCEAP
2110 2120 2130 2140 2150 2160
LAQETFTDLS NQWDSTLHLA NTYLSHQEKL VLEGEKYLQS KEDLRLMLTE LKKQQEAGFA
2170 2180 2190 2200 2210 2220
LQPGLPEKQA QLKIYKKFLQ KAQDLTSLLE ELKSQGNYLL ECTKNPSFSE EPWLEVKHLH
2230 2240 2250 2260 2270 2280
ESLLQQLQDS VQKLEGHVQE HSSYQVCLTD LSSTLDDISK EYFSLCDGSK DQIMAKERMQ
2290 2300 2310 2320 2330 2340
KLQELESRLR FQGGALKKAS ALAKSIKQNT SSVGQKIIKD DIRSLKYKQK DLENRIESAK
2350 2360 2370 2380 2390 2400
QETENGLNSI LKSKSSTEKH VKFSLPVEEM PATSEVPKPT RESAAVGESG GARETNTNSA
2410 2420 2430 2440 2450 2460
VEMILSKQLS LNVQESMQNA QDEREVNELQ NQPLELDIML RNEQLKGMEE LSTHLEARRA
2470 2480 2490 2500 2510 2520
AIELLEQSQH LNQTEEQALV LPAARPSVCH LGSLQQELHT LKKTKERQYG LLSGFQDQLV
2530 2540 2550 2560 2570 2580
MAEASLNTSL AEVESLKIGS LDSATYLGKI KKFLGSVENQ QGSLSKLRTE WAHLSSLLAA
2590 2600 2610 2620 2630 2640
ADQKLVESQM KHLEHGWELV EQLAHRKCFQ QATEHSELTC LLEKLQDLKV SLHQQQQRLT
2650 2660 2670 2680 2690 2700
LSLNSPGQQA AIVDMVTPAA ELQAIKCEFS GLKWQAELHM KRLWGEKDKK TLEDAINNLN
2710 2720 2730 2740 2750 2760
KQMEALEPLN REVENRIKKC ELQNRIKETL SWVKNTMAEL VVPIALLPDN ILSQIRKCKL
2770 2780 2790 2800 2810 2820
IHDGILGNQQ AVELLVEEVR GITPSLAPCE GDGLNALLED LQSQHQALLL KSTERSQQLE
2830 2840 2850 2860 2870 2880
LKLEEKSKLF AIIGKVQLTL EESETLMSPT GDRASTEAEL ERRLAILKAS QQQLQDTESA
2890 2900 2910 2920 2930 2940
LSAHLQELTN AYKDANVFER LFLDDQLKNL KARTNRTQRF LQNNGSELKQ KMESYREFHD
2950 2960 2970 2980 2990 3000
KAAVLQKEAE CILHGGLLPL RQELEQDAKE QLGNLRDKLA AIRGSLSQVL TSEEVFDTIG
3010 3020 3030 3040 3050 3060
LSWDGSLLAR LQTQVLERER EVEGKIKQLD TFLIARDRHQ ASISKIRAVD LQIKKGAESL
3070 3080 3090 3100 3110 3120
LKVPSMSPES TLLNAQTLIQ KIEKSKRLRD EIIRKLSKNE AFDDSFKESE MQRLKLCAEE
3130 3140 3150 3160 3170 3180
NSRLQEALQN MLLELQPREM GEKEFREKLE NALHVLKQIQ SRLQQPLCVN LGVQHIQHEK
3190 3200 3210 3220 3230 3240
ETWEAFGEQV EAEMCGLRAV RITEEQREEN DSGTGGMEAK LRDIEGLHME LSKSISLRAD
3250 3260 3270 3280 3290 3300
VLNDAYDSAN RYDELVAGAL RIITSLEATL LSYRVDLHNP QKTLELAHLK QEELQSSVAD
3310 3320 3330 3340 3350 3360
LRSLTETLGA ISSPEAKEQL RCTLEVLAAK NSALKAGLEA QEAEEERCLE NYKCFRKMKE
3370 3380 3390 3400 3410 3420
EICSRLRKME MDLGQSIFPL PRSYKEALAR LEQSKALTSN LLSTKEDLVK LRQLLRHLRC
3430 3440 3450 3460 3470 3480
RSTENDATCA LGVASALWEK WLSLLEAARE WQQWGGELKR EWKFISEEIE REAIILETLQ
3490 3500 3510 3520 3530 3540
EDLPEISKTN AAPTEELWQL LDSLCQHQES VEKQQLLLAL LLQRVRSIQN IPEGTETGET
3550 3560 3570 3580 3590 3600
IPALQEIGSM QERCDRLLHT TRKNKDLVQA EIQAQQSFLK EIKDVKRVFE QISTSFPNLA
3610 3620 3630 3640 3650 3660
PEGHPERAEQ FEELRSILQK GKLSFENIME KLRIKYSEMY SIVPAEIGSQ VEECRSALED
3670 3680 3690 3700 3710 3720
AEEKMSSEVS KSSPSSIMRR KIERINNGLH CVEKMLQQKS RNIEEAHEIQ KKIWDELDLW
3730 3740 3750 3760 3770 3780
HSKLNELDSE VQDFVEQDPG QAQEWMDNLM APFQQHQQVS QRAESRTSQL NKATIKMEEY
3790 3800 3810 3820 3830 3840
NDLLKSTEVW IEKTSCLLAN PACYDSSRTL SHRASTLQMA LEDSEQKHSL LHSIFTDLED
3850 3860 3870 3880 3890 3900
LSIIFETDDL IQTIHELSDQ VAALQQQIME ALPHVQQVAD DVVAIESEVK AMEKKVAKIK
3910 3920 3930 3940 3950 3960
AILLSKEIFD FPPEEHLKHG EVILENIHPM KKTIAEIMTY QVELRLPQTG TKPLPVFQRT
3970 3980 3990 4000 4010 4020
SQLLQDVKLL ENVTQEQNEL LKVVIKQTAE CDEEIDSLKQ MLTNYSAEIS PEHVSQNQVA
4030 4040 4050 4060 4070 4080
DLPSLQGEME RLEKQILNLN QKKEDLLVDL KTAVLNLHEH LKQEQQEVGD KPSAGASECT
4090 4100 4110 4120 4130 4140
VAERDASERK LSRTNSMSFL PVVKEEAEES SVKSEDGRRR TEPPSASWSF LGKHSKDLEG
4150 4160 4170 4180 4190 4200
DGASSSSSAT IVQDADGRIS TCDSSMVHII APDSGSTEEG PAPSPRLSQT DEGATPPIEA
4210 4220 4230 4240 4250 4260
ALLDFPREQG AFESTVERSR PRPADILRVC KTQVAKLELW LQQANVAFEP ETVDADMQQV
4270 4280 4290 4300 4310 4320
VEEELAGCQA MLTEIEYKVA SLLETCKDQG LGDCGTTQQE AEALSWKLKT VKCNLEKVQM
4330 4340 4350 4360 4370 4380
VLQEKFSEDQ HPSTLKKPSE PHDVDQPAGL SELDSVLTER PQFSRQKDAP QPQILELKPS
4390 4400 4410 4420 4430 4440
EQKDLIKFTE LNAKKTWLQG HQENEDANRQ SASSSKVPSP GNAASDSTLP LQAQSGDKWQ
4450 4460 4470 4480 4490 4500
YLHHELTSRP NPSVPQLVEP QVALTTSTLP SVSVYNFRCP TADELQAYTT QLEELRQEAN
4510 4520 4530 4540 4550 4560
TIQTQGSMTE ETYISLDKRL FELFLSLSRC LGSVEGLLQR PGLLREDACA QQVFFQKLAL
4570 4580 4590 4600 4610 4620
ELKKLYLALG DKKDDFLKAV TWPGKEATLL PECIDALTVS LESVQSRAAW RDASLKAGLE
4630 4640 4650 4660 4670 4680
HSRSYQNEVK RLYSQLIKKK TALQQSLNEI SGQSISKQLQ KADVHTAELQ NSEKQVAKLR
4690 4700 4710 4720 4730 4740
DEGERLRFPH GLLQDVYKLE DVLDSMWGIL RARYLELSSP FLSKSLQTLL QGMAELVSIG
4750 4760 4770 4780 4790 4800
KGKLAADPLQ HAKSKAALQA QLQDHKAFFQ KLVADMLLIQ TYSATMFPPS LQKGEGFGAE
4810 4820 4830 4840 4850 4860
QVAEVRALEE EACLRGAQLQ SMLQKWEEFD DNYASLEKDL EALISSLPSV SLVEETEERL
4870 4880 4890 4900 4910 4920
LERISFYQQI KRNIDGKHAR LCQTLNEGRQ LAASVSCPEP EGQIARLEEQ WLSLNKRIDQ
4930 4940 4950 4960 4970 4980
ELHRLQTLLK HLLSYSRDSD ELTRWLETSQ QTLNYWKEQS LNVSQDLNTI RSNIDRFFKF
4990 5000 5010 5020 5030 5040
SKEVDERSSL KSAVMSTGNQ LLHLKEADTA TLRASLAQFE QKWTVLITQL PDIQEKLHQL
5050 5060 5070 5080 5090 5100
QMEKLPSREA ISEMISWMNA VEPQAAGKDT ELSKSSASQV KHLLQKLKEF RMEMDYKQWV
5110 5120 5130 5140 5150 5160
VDFVNQSLLQ LSTCDVESKR YERTEFAEHL GEMNRQWQRV HGTLNRKIQH LEQLLESITE
5170 5180 5190 5200 5210 5220
NENKVQNLNS WLEAQEERLK MLQKPESAVS MEKLLLDCQD IENQLALKSK ALDELRQSSL
5230 5240 5250 5260 5270 5280
TMDGGDVPLL EDMASGIVEL FQKKNNVTSQ VHQLRASVQS VLQEWKACDK LYDEATMRTT
5290 5300 5310 5320 5330 5340
QLTYSMEHSK PAVLSLQALA CQVQNLEALQ DEAENGERSW EKLQEVIGRL KASCPSMAGI
5350 5360 5370 5380 5390 5400
IEEKCQDAHS RWTQVNQDLA DQLQEARGQL QLWKAPHNAH AEAAAWLQQQ EAKFQQLANT
5410 5420 5430 5440 5450 5460
NLSGDNLADI LPRALKDIKG LQSDLQKTKE AFLENSTLSD QLPQPEERST PGLHSGQRHS
5470 5480 5490 5500 5510 5520
LQTAAYLEKM LLAKSNEFEI VLAQFKDFTD RLAYSKDLIV HKEENLNKLY HEEKEEVPDL
5530 5540 5550 5560 5570 5580
FLNHVLALTA QSPDIERLNE ESLRLPLSDV TIKTLQSLNR QWIRATATAL DHYSELQGNG
5590 5600 5610 5620 5630 5640
LNEKFLHYCE RWIQVLEKIQ ESLSVEVAHS LPALLEQQKT YEILEAEVST NQAVADAYVT
5650 5660 5670 5680 5690 5700
QSLQLLDTAE IEKRPEFVSE FSKLSDQWQR AARGVRQRKC DISRLVTQWR FFTTSVEDLL
5710 5720 5730 5740 5750 5760
RFLADTSQLL SAVKEQDCYS LCQTRRLVHE LKSKEIHLQR WRTTYALALE AGEKLRNTPS
5770 5780 5790 5800 5810 5820
PETREFVDGQ ISRLQESWKD TELSLGEVIS RLQSTAETWD QCKKKIKKLK KRLQALKAQS
5830 5840 5850 5860 5870 5880
EDPLPELHEA LHEEKELIKE VEKSLANWTH SLKELQTMKA DLSQHILAED VTVLKEQIQL
5890 5900 5910 5920 5930 5940
LHRQWEDLCL RVAIRKQEIE DRLNSWIVFN EKNKELCAWL VQMENKVLQT ADVSIEEMIE
5950 5960 5970 5980 5990 6000
KLQKDCMEEI SLFTENKLQL KQMGDQLIKA SSKAKAAELE EKLSKINDRW QHLFDVIGSR
6010 6020 6030 6040 6050 6060
VKKLKETFAF IQQLDKNMSN LRTWLARIES ELSKPVVYDV CDNQEIQKRL AEQQDLQRDI
6070 6080 6090 6100 6110 6120
EQHSAGVESV FNICDVLLHD SDACANETEC DSIQQTTRSL DRRWRNICAM SMERRMKIEE
6130 6140 6150 6160 6170 6180
TWRLWQKFLD DYSRFEDWLK SAERTAACPN SSEVLYTNAK EELKRFEAFQ RQIHERLTQL
6190 6200 6210 6220 6230 6240
ELINKQYRRL ARENRTDTAS KLKQMVHEGN QRWDNLQKRV TAILRRLRYF TNQREEFEGT
6250 6260 6270 6280 6290 6300
RESILVWLTE MDLQLTNVEH FSESDAEDKM RQLNGFQQEI TLNTNKIDQL IVFGEQLIQK
6310 6320 6330 6340 6350 6360
SEPLDAVLIE DELEELHRYC QEVFGRVSRF HRRLTSHTPG LDDEKEASEN ETDIEDPREI
6370 6380 6390 6400 6410 6420
QADSWRKRRE SEEPTSPQSL CHLVPPALGH ERSGCETPVS VDSIPLEWDH TGDVGGSSSH
6430 6440 6450 6460 6470 6480
EDDEEGPFYS ALSGKSISEG HPWHVPDSPS HSKHHYKHME GDRTEAPVPT DASTPFKSDY
6490 6500 6510 6520 6530 6540
VKLLLRQGTD DSKEGLKEAQ QEDEQLATLT GQQPGAFDRW ELIQAQELHS KLRLKQTVQQ
6550 6560 6570 6580 6590 6600
LKSDIGSIAA WLGKTEAELE ALKLAEPPSD IQEIALRVKR LQEILKAFDT YKALMVSVNV
6610 6620 6630 6640 6650 6660
SHKEYLPSQS PEATELQNRL HQLSLSWDSV QGVLDSWRGD LRQSLMQCQD FHQLSQDLLL
6670 6680 6690 6700 6710 6720
WLATAESRRQ KAHVTSPEAD RQVLLECQKD LMRLEKELVA RQPQVSSLRE ISSSLLVKGQ
6730 6740 6750 6760 6770 6780
GEDYIEAEEK VHVIEKKLKQ LQEQVAQDLM SLQRSLDPDA SLTSFDEVDS GEQLPAAFAK
6790 6800 6810 6820 6830 6840
SPRPRWTFLE EEEEEEETDS RMPHLDSPGS SQPRRSFLSR VIRAALPLQL LLLLLLLLAC
6850 6860 6870
LLPASEDDYS CTQANNFARS FYPMLRYTNG PPPT
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q6ZWQ0-1-unknown | MAASPV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q6ZWQ0-1-unknown | MAASPV... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt91216 | |||
| Q6ZWQ0-4995-unknown | MSTGNQ... | 4995 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt91217 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GPPPT | 6874 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...GPPPT | 6874 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt86835 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|