TopFIND 4.0

Q715S9: Thioredoxin domain-containing protein 3

General Information

Protein names
- Thioredoxin domain-containing protein 3
- NME/NM23 family member 8
- Spermatid-specific thioredoxin-2
- Sptrx-2
Gene names Nme8
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q715S9

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASKKREVQL QSVVNSQNLW DEMLLNKGLT VIDVYQAWCG PCKAVQALFR KLKNELNEDE 
        70         80         90        100        110        120 
LLHFVVAEAD SIVTLQPFRD KCEPVFLFSL NGKIIAKIQG ANAPLINRKV IALIDEEKKI 
       130        140        150        160        170        180 
AAGEMARPQY VEIPLVDSLD EEYGEVHYES NVEVYNMAVI NPDAVLMRKN LEIKEKITKE 
       190        200        210        220        230        240 
GFIIEIQENM LLPEEVAREF YNHMIDEPDF EEFVYSMTNR LSCVLIISQG EDTEVIEEEA 
       250        260        270        280        290        300 
LPQSDDEEEP DPLEEPHVRF APMLVKKKRD SLQEYMDRQH MSDYCHVEDD AVKVSKFIDI 
       310        320        330        340        350        360 
LFPDFKTMKS TNVQRTLGLL YPEVCEEEKD NVLDIIQNEG FTILMQRQVV LSEEEARAVC 
       370        380        390        400        410        420 
HVHEDEDYFD NLIGYMCSNN SYILVLMREH SVERWKELIG PKTVEEAYAS HPDSLCVRFA 
       430        440        450        460        470        480 
SGNFPVNQFY GSSSKAAAET EIEHFFPPQS TLALIKPHVS HKERMEILKA IRDARFELTQ 
       490        500        510        520        530        540 
MKEMHLTPEH ASKVYFKITG KDFYKNVLDV LSSGMSVVMI LTKWNAVGEW RRMMGPVDPE 
       550        560        570        580    
EAKLLSPNSL RARYGIDVLR NAVHGASNMS EAATAISNVF TESNFEN

Isoforms

- Isoform 2 of Thioredoxin domain-containing protein 3

Sequence View

        10         20         30         40         50         60 
MASKKREVQL QSVVNSQNLW DEMLLNKGLT VIDVYQAWCG PCKAVQALFR KLKNELNEDE 
        70         80         90        100        110        120 
LLHFVVAEAD SIVTLQPFRD KCEPVFLFSL NGKIIAKIQG ANAPLINRKV IALIDEEKKI 
       130        140        150        160        170        180 
AAGEMARPQY VEIPLVDSLD EEYGEVHYES NVEVYNMAVI NPDAVLMRKN LEIKEKITKE 
       190        200        210        220        230        240 
GFIIEIQENM LLPEEVAREF YNHMIDEPDF EEFVYSMTNR LSCVLIISQG EDTEVIEEEA 
       250        260        270        280        290        300 
LPQSDDEEEP DPLEEPHVRF APMLVKKKRD SLQEYMDRQH MSDYCHVEDD AVKVSKFIDI 
       310        320        330        340        350        360 
LFPDFKTMKS TNVQRTLGLL YPEVCEEEKD NVLDIIQNEG FTILMQRQVV LSEEEARAVC 
       370        380        390        400        410        420 
HVHEDEDYFD NLIGYMCSNN SYILVLMREH SVERWKELIG PKTVEEAYAS HPDSLCVRFA 
       430        440        450        460        470        480 
SGNFPVNQFY GSSSKAAAET EIEHFFPPQS TLALIKPHVS HKERMEILKA IRDARFELTQ 
       490        500        510        520        530        540 
MKEMHLTPEH ASKVYFKITG KDFYKNVLDV LSSGMSVVMI LTKWNAVGEW RRMMGPVDPE 
       550        560        570        580    
EAKLLSPNSL RARYGIDVLR NAVHGASNMS EAATAISNVF TESNFEN



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q715S9-1-unknown MASKKR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q715S9-1-unknown MASKKR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193670

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SNFEN 587 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SNFEN 587 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt153616

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)