TopFIND 4.0

Q715T0: Thioredoxin domain-containing protein 3

General Information

Protein names
- Thioredoxin domain-containing protein 3
- NME/NM23 family member 8
- Spermatid-specific thioredoxin-2
- Sptrx-2
Gene names Nme8
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q715T0

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASKKREVQL QSVVNSQNLW DEMLLNKGLT VIDVYQAWCG PCKAVQSLFR KLKNELNEDE 
        70         80         90        100        110        120 
ILHFVVAEAD NIVTLQPFRD KCEPVFLFSL NGKIIAKIQG ANAPLINRKV ITLIDEERKI 
       130        140        150        160        170        180 
VAGEMDRPQY VEIPLVDAID EEYGEVQYES AAEVYNMAII KPDAVLMRKN IEVREKIAKE 
       190        200        210        220        230        240 
GFVIEIQENL ILPEEVVREF YTHIADQPDF EEFVVSMTNG LSCVLIVSQE DSEVIQEETL 
       250        260        270        280        290        300 
PQTDTEEEPG VLEEPHVRFA PVMIKKKRDS LQEYMDRQHM SDYCDVEDDA VKVSKLIDIL 
       310        320        330        340        350        360 
FPDFKTMKST NVQTTLALLH PDICEEEKDD VLNVIHNEGF TILMQRQIVL SEEEARTVCK 
       370        380        390        400        410        420 
IHENEEYFDN LIGHMTSNHS YVLALRRENG VEYWKTLIGP KTIEEAYASH PQSLCVQFAS 
       430        440        450        460        470        480 
GNFPTNQFYG SSSKAAAEKE IAHFFPPQST LALIKPHVTH KERMEILKTI KEAGFELTLM 
       490        500        510        520        530        540 
KEMHLTPEHA NKIYFKITGK DFYKNVLEVL SLGMSLVMVL TKWNAVAEWR RMVGPVDPEE 
       550        560        570        580    
AKLLSPESLR AKYGLDILRN AVHGASNFSE ASEIISNVFT EGNPEN

Isoforms

- Isoform 2 of Thioredoxin domain-containing protein 3

Sequence View

        10         20         30         40         50         60 
MASKKREVQL QSVVNSQNLW DEMLLNKGLT VIDVYQAWCG PCKAVQSLFR KLKNELNEDE 
        70         80         90        100        110        120 
ILHFVVAEAD NIVTLQPFRD KCEPVFLFSL NGKIIAKIQG ANAPLINRKV ITLIDEERKI 
       130        140        150        160        170        180 
VAGEMDRPQY VEIPLVDAID EEYGEVQYES AAEVYNMAII KPDAVLMRKN IEVREKIAKE 
       190        200        210        220        230        240 
GFVIEIQENL ILPEEVVREF YTHIADQPDF EEFVVSMTNG LSCVLIVSQE DSEVIQEETL 
       250        260        270        280        290        300 
PQTDTEEEPG VLEEPHVRFA PVMIKKKRDS LQEYMDRQHM SDYCDVEDDA VKVSKLIDIL 
       310        320        330        340        350        360 
FPDFKTMKST NVQTTLALLH PDICEEEKDD VLNVIHNEGF TILMQRQIVL SEEEARTVCK 
       370        380        390        400        410        420 
IHENEEYFDN LIGHMTSNHS YVLALRRENG VEYWKTLIGP KTIEEAYASH PQSLCVQFAS 
       430        440        450        460        470        480 
GNFPTNQFYG SSSKAAAEKE IAHFFPPQST LALIKPHVTH KERMEILKTI KEAGFELTLM 
       490        500        510        520        530        540 
KEMHLTPEHA NKIYFKITGK DFYKNVLEVL SLGMSLVMVL TKWNAVAEWR RMVGPVDPEE 
       550        560        570        580    
AKLLSPESLR AKYGLDILRN AVHGASNFSE ASEIISNVFT EGNPEN



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q715T0-1-unknown MASKKR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q715T0-1-unknown MASKKR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93475

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GNPEN 586 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)