TopFIND 4.0

Q71RH2: Ceramide synthase {ECO:0000250|UniProtKB:Q7TNV1}

General Information

Protein names
- Ceramide synthase {ECO:0000250|UniProtKB:Q7TNV1}
- 2.3.1.- {ECO:0000250|UniProtKB:Q7TNV1}
- Protein FAM57B
Gene names FAM57B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q71RH2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLTPMVAGGV VFPGLFLLSK NTLQRLPQLR WEEADAVIVS ARLVSSVQAI MASTAGYIVS 
        70         80         90        100        110        120 
TSCKHIIDDQ HWLSSAYTQF AVPYFIYDIY AMFLCHWHKH QVKGHGGDDG AARAPGSTWA 
       130        140        150        160        170        180 
IARGYLHKEF LMVLHHAAMV LVCFPLSVVW RQGKGDFFLG CMLMAEVSTP FVCLGKILIQ 
       190        200        210        220        230        240 
YKQQHTLLHK VNGALMLLSF LCCRVLLFPY LYWAYGRHAG LPLLAVPLAI PAHVNLGAAL 
       250        260        270    
LLAPQLYWFF LICRGACRLF WPRSRPPPAC QAQD

Isoforms

- Isoform 2 of Protein FAM57B - Isoform 2 of Ceramide synthase

Sequence View

        10         20         30         40         50         60 
MLTPMVAGGV VFPGLFLLSK NTLQRLPQLR WEEADAVIVS ARLVSSVQAI MASTAGYIVS 
        70         80         90        100        110        120 
TSCKHIIDDQ HWLSSAYTQF AVPYFIYDIY AMFLCHWHKH QVKGHGGDDG AARAPGSTWA 
       130        140        150        160        170        180 
IARGYLHKEF LMVLHHAAMV LVCFPLSVVW RQGKGDFFLG CMLMAEVSTP FVCLGKILIQ 
       190        200        210        220        230        240 
YKQQHTLLHK VNGALMLLSF LCCRVLLFPY LYWAYGRHAG LPLLAVPLAI PAHVNLGAAL 
       250        260        270    
LLAPQLYWFF LICRGACRLF WPRSRPPPAC QAQD         10         20         30         40         50         60 
MLTPMVAGGV VFPGLFLLSK NTLQRLPQLR WEEADAVIVS ARLVSSVQAI MASTAGYIVS 
        70         80         90        100        110        120 
TSCKHIIDDQ HWLSSAYTQF AVPYFIYDIY AMFLCHWHKH QVKGHGGDDG AARAPGSTWA 
       130        140        150        160        170        180 
IARGYLHKEF LMVLHHAAMV LVCFPLSVVW RQGKGDFFLG CMLMAEVSTP FVCLGKILIQ 
       190        200        210        220        230        240 
YKQQHTLLHK VNGALMLLSF LCCRVLLFPY LYWAYGRHAG LPLLAVPLAI PAHVNLGAAL 
       250        260        270    
LLAPQLYWFF LICRGACRLF WPRSRPPPAC QAQD



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q71RH2-1-unknown MLTPMV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q71RH2-51-unknown MASTAG... 51 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74636

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CQAQD 274 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...CQAQD 274 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt70254

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)