Q7L1W4: Volume-regulated anion channel subunit LRRC8D

General Information

Protein names	- Volume-regulated anion channel subunit LRRC8D - Leucine-rich repeat-containing protein 5 - Leucine-rich repeat-containing protein 8D
Gene names	LRRC8D
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7L1W4

1 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MFTLAEVASL NDIQPTYRIL KPWWDVFMDY LAVVMLMVAI FAGTMQLTKD QVVCLPVLPS
        70         80         90        100        110        120
PVNSKAHTPP GNAEVTTNIP KMEAATNQDQ DGRTTNDISF GTSAVTPDIP LRATYPRTDF
       130        140        150        160        170        180
ALPNQEAKKE KKDPTGRKTN LDFQQYVFIN QMCYHLALPW YSKYFPYLAL IHTIILMVSS
       190        200        210        220        230        240
NFWFKYPKTC SKVEHFVSIL GKCFESPWTT KALSETACED SEENKQRITG AQTLPKHVST
       250        260        270        280        290        300
SSDEGSPSAS TPMINKTGFK FSAEKPVIEV PSMTILDKKD GEQAKALFEK VRKFRAHVED
       310        320        330        340        350        360
SDLIYKLYVV QTVIKTAKFI FILCYTANFV NAISFEHVCK PKVEHLIGYE VFECTHNMAY
       370        380        390        400        410        420
MLKKLLISYI SIICVYGFIC LYTLFWLFRI PLKEYSFEKV REESSFSDIP DVKNDFAFLL
       430        440        450        460        470        480
HMVDQYDQLY SKRFGVFLSE VSENKLREIS LNHEWTFEKL RQHISRNAQD KQELHLFMLS
       490        500        510        520        530        540
GVPDAVFDLT DLDVLKLELI PEAKIPAKIS QMTNLQELHL CHCPAKVEQT AFSFLRDHLR
       550        560        570        580        590        600
CLHVKFTDVA EIPAWVYLLK NLRELYLIGN LNSENNKMIG LESLRELRHL KILHVKSNLT
       610        620        630        640        650        660
KVPSNITDVA PHLTKLVIHN DGTKLLVLNS LKKMMNVAEL ELQNCELERI PHAIFSLSNL
       670        680        690        700        710        720
QELDLKSNNI RTIEEIISFQ HLKRLTCLKL WHNKIVTIPP SITHVKNLES LYFSNNKLES
       730        740        750        760        770        780
LPVAVFSLQK LRCLDVSYNN ISMIPIEIGL LQNLQHLHIT GNKVDILPKQ LFKCIKLRTL
       790        800        810        820        830        840
NLGQNCITSL PEKVGQLSQL TQLELKGNCL DRLPAQLGQC RMLKKSGLVV EDHLFDTLPL
       850
EVKEALNQDI NIPFANGI

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7L1W4-1-unknown	MFTLAE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VFMDYL	30	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435609
...RATYPR	116	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415117
...RTDFAL	121	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435504
...FWFKYP	186	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000433422
...VPSMTI	274	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000405784
...FANGI	858	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)