Q7L5A8: Fatty acid 2-hydroxylase {ECO:0000303|PubMed:15337768, ECO:0000303|PubMed:15863841, ECO:0000303|PubMed:17355976, ECO:0000303|PubMed:22517924}
| Protein names | - Fatty acid 2-hydroxylase {ECO:0000303|PubMed:15337768, ECO:0000303|PubMed:15863841, ECO:0000303|PubMed:17355976, ECO:0000303|PubMed:22517924} - 1.14.18.- {ECO:0000269|PubMed:15337768, ECO:0000269|PubMed:15863841, ECO:0000269|PubMed:22517924} - Fatty acid alpha-hydroxylase {ECO:0000303|PubMed:15863841} |
|---|---|
| Gene names | FA2H |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q7L5A8 |
2
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAPAPPPAAS FSPSEVQRRL AAGACWVRRG ARLYDLSSFV RHHPGGEQLL RARAGQDISA
70 80 90 100 110 120
DLDGPPHRHS ANARRWLEQY YVGELRGEQQ GSMENEPVAL EETQKTDPAM EPRFKVVDWD
130 140 150 160 170 180
KDLVDWRKPL LWQVGHLGEK YDEWVHQPVT RPIRLFHSDL IEGLSKTVWY SVPIIWVPLV
190 200 210 220 230 240
LYLSWSYYRT FAQGNVRLFT SFTTEYTVAV PKSMFPGLFM LGTFLWSLIE YLIHRFLFHM
250 260 270 280 290 300
KPPSDSYYLI MLHFVMHGQH HKAPFDGSRL VFPPVPASLV IGVFYLCMQL ILPEAVGGTV
310 320 330 340 350 360
FAGGLLGYVL YDMTHYYLHF GSPHKGSYLY SLKAHHVKHH FAHQKSGFGI STKLWDYCFH
370
TLTPEKPHLK TQ
Isoforms
- Isoform 2 of Fatty acid 2-hydroxylaseSequence View
10 20 30 40 50 60
MAPAPPPAAS FSPSEVQRRL AAGACWVRRG ARLYDLSSFV RHHPGGEQLL RARAGQDISA
70 80 90 100 110 120
DLDGPPHRHS ANARRWLEQY YVGELRGEQQ GSMENEPVAL EETQKTDPAM EPRFKVVDWD
130 140 150 160 170 180
KDLVDWRKPL LWQVGHLGEK YDEWVHQPVT RPIRLFHSDL IEGLSKTVWY SVPIIWVPLV
190 200 210 220 230 240
LYLSWSYYRT FAQGNVRLFT SFTTEYTVAV PKSMFPGLFM LGTFLWSLIE YLIHRFLFHM
250 260 270 280 290 300
KPPSDSYYLI MLHFVMHGQH HKAPFDGSRL VFPPVPASLV IGVFYLCMQL ILPEAVGGTV
310 320 330 340 350 360
FAGGLLGYVL YDMTHYYLHF GSPHKGSYLY SLKAHHVKHH FAHQKSGFGI STKLWDYCFH
370
TLTPEKPHLK TQ
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q7L5A8-1-unknown | MAPAPP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q7L5A8-214-unknown | MFPGLF... | 214 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000442334 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...FVMHGQ | 258 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000464576 | |||
| ...HLKTQ | 372 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|