Q7L622: G2/M phase-specific E3 ubiquitin-protein ligase

General Information

Protein names	- G2/M phase-specific E3 ubiquitin-protein ligase - 2.3.2.26 - G2/M phase-specific HECT-type E3 ubiquitin transferase
Gene names	G2E3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7L622

2 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNESKPGDSQ NLACVFCRKH DDCPNKYGEK KTKEKWNLTV HYYCLLMSSG IWQRGKEEEG
        70         80         90        100        110        120
VYGFLIEDIR KEVNRASKLK CCVCKKNGAS IGCVAPRCKR SYHFPCGLQR ECIFQFTGNF
       130        140        150        160        170        180
ASFCWDHRPV QIITSNNYRE SLPCTICLEF IEPIPSYNIL RSPCCKNAWF HRDCLQVQAI
       190        200        210        220        230        240
NAGVFFFRCT ICNNSDIFQK EMLRMGIHIP EKDASWELEE NAYQELLQHY ERCDVRRCRC
       250        260        270        280        290        300
KEGRDYNAPD SKWEIKRCQC CGSSGTHLAC SSLRSWEQNW ECLECRGIIY NSGEFQKAKK
       310        320        330        340        350        360
HVLPNSNNVG ITDCLLEESS PKLPRQSPGS QSKDLLRQGS KFRRNVSTLL IELGFQIKKK
       370        380        390        400        410        420
TKRLYINKAN IWNSALDAFR NRNFNPSYAI EVAYVIENDN FGSEHPGSKQ EFLSLLMQHL
       430        440        450        460        470        480
ENSSLFEGSL SKNLSLNSQA LKENLYYEAG KMLAISLVHG GPSPGFFSKT LFNCLVYGPE
       490        500        510        520        530        540
NTQPILDDVS DFDVAQIIIR INTATTVADL KSIINECYNY LELIGCLRLI TTLSDKYMLV
       550        560        570        580        590        600
KDILGYHVIQ RVHTPFESFK QGLKTLGVLE KIQAYPEAFC SILCHKPESL SAKILSELFT
       610        620        630        640        650        660
VHTLPDVKAL GFWNSYLQAV EDGKSTTTME DILIFATGCS SIPPAGFKPT PSIECLHVDF
       670        680        690        700
PVGNKCNNCL AIPITNTYKE FQENMDFTIR NTLRLEKEES SHYIGH

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7L622-1-unknown	MNESKP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7L622-47-unknown	MSSGIW...	47		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000391068

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RASKLK	79	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452275
...FTGNFA	120	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000448745
...HRPVQI	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000451147
...RDCLQV	176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000446615
...LGFQIK	357	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000448515
...HYIGH	706	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)