Q7L8W6: Diphthine--ammonia ligase

General Information

Protein names	- Diphthine--ammonia ligase - 6.3.1.14 - ATP-binding domain-containing protein 4 - Diphthamide synthase - Diphthamide synthetase - Protein DPH6 homolog
Gene names	DPH6
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7L8W6

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Diphthine--ammonia ligase - Isoform 2 of Diphthine--ammonia ligase

Sequence View

        10         20         30         40         50         60
MRVAALISGG KDSCYNMMQC IAAGHQIVAL ANLRPAENQV GSDELDSYMY QTVGHHAIDL
        70         80         90        100        110        120
YAEAMALPLY RRTIRGRSLD TRQVYTKCEG DEVEDLYELL KLVKEKEEVE GISVGAILSD
       130        140        150        160        170        180
YQRIRVENVC KRLNLQPLAY LWQRNQEDLL REMISSNIQA MIIKVAALGL DPDKHLGKTL
       190        200        210        220        230        240
DQMEPYLIEL SKKYGVHVCG EGGEYETFTL DCPLFKKKII VDSSEVVIHS ADAFAPVAYL
       250        260
RFLELHLEDK VSSVPDNYRT SNYIYNF         10         20         30         40         50         60
MRVAALISGG KDSCYNMMQC IAAGHQIVAL ANLRPAENQV GSDELDSYMY QTVGHHAIDL
        70         80         90        100        110        120
YAEAMALPLY RRTIRGRSLD TRQVYTKCEG DEVEDLYELL KLVKEKEEVE GISVGAILSD
       130        140        150        160        170        180
YQRIRVENVC KRLNLQPLAY LWQRNQEDLL REMISSNIQA MIIKVAALGL DPDKHLGKTL
       190        200        210        220        230        240
DQMEPYLIEL SKKYGVHVCG EGGEYETFTL DCPLFKKKII VDSSEVVIHS ADAFAPVAYL
       250        260
RFLELHLEDK VSSVPDNYRT SNYIYNF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q7L8W6-1-unknown	MRVAAL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q7L8W6-1-unknown	MRVAAL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73188
Q7L8W6-49-unknown	MYQTVG...	49	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453967
Q7L8W6-49-unknown	MYQTVG...	49	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196087
Q7L8W6-125-unknown	RVENVC...	125	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454015

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...PLFKKK	217	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000453967
...YIYNF	267	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...YIYNF	267		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...YIYNF	267		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)