TopFIND 4.0

Q7LGA3: Heparan sulfate 2-O-sulfotransferase 1

General Information

Protein names
- Heparan sulfate 2-O-sulfotransferase 1
- 2-O-sulfotransferase
- 2OST
- 2.8.2.-
Gene names HS2ST1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q7LGA3

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGLLRIMMPP KLQLLAVVAF AVAMLFLENQ IQKLEESRSK LERAIARHEV REIEQRHTMD 
        70         80         90        100        110        120 
GPRQDATLDE EEDMVIIYNR VPKTASTSFT NIAYDLCAKN KYHVLHINTT KNNPVMSLQD 
       130        140        150        160        170        180 
QVRFVKNITS WKEMKPGFYH GHVSYLDFAK FGVKKKPIYI NVIRDPIERL VSYYYFLRFG 
       190        200        210        220        230        240 
DDYRPGLRRR KQGDKKTFDE CVAEGGSDCA PEKLWLQIPF FCGHSSECWN VGSRWAMDQA 
       250        260        270        280        290        300 
KYNLINEYFL VGVTEELEDF IMLLEAALPR FFRGATELYR TGKKSHLRKT TEKKLPTKQT 
       310        320        330        340        350    
IAKLQQSDIW KMENEFYEFA LEQFQFIRAH AVREKDGDLY ILAQNFFYEK IYPKSN

Isoforms

- Isoform 2 of Heparan sulfate 2-O-sulfotransferase 1 - Isoform 3 of Heparan sulfate 2-O-sulfotransferase 1

Sequence View

        10         20         30         40         50         60 
MGLLRIMMPP KLQLLAVVAF AVAMLFLENQ IQKLEESRSK LERAIARHEV REIEQRHTMD 
        70         80         90        100        110        120 
GPRQDATLDE EEDMVIIYNR VPKTASTSFT NIAYDLCAKN KYHVLHINTT KNNPVMSLQD 
       130        140        150        160        170        180 
QVRFVKNITS WKEMKPGFYH GHVSYLDFAK FGVKKKPIYI NVIRDPIERL VSYYYFLRFG 
       190        200        210        220        230        240 
DDYRPGLRRR KQGDKKTFDE CVAEGGSDCA PEKLWLQIPF FCGHSSECWN VGSRWAMDQA 
       250        260        270        280        290        300 
KYNLINEYFL VGVTEELEDF IMLLEAALPR FFRGATELYR TGKKSHLRKT TEKKLPTKQT 
       310        320        330        340        350    
IAKLQQSDIW KMENEFYEFA LEQFQFIRAH AVREKDGDLY ILAQNFFYEK IYPKSN         10         20         30         40         50         60 
MGLLRIMMPP KLQLLAVVAF AVAMLFLENQ IQKLEESRSK LERAIARHEV REIEQRHTMD 
        70         80         90        100        110        120 
GPRQDATLDE EEDMVIIYNR VPKTASTSFT NIAYDLCAKN KYHVLHINTT KNNPVMSLQD 
       130        140        150        160        170        180 
QVRFVKNITS WKEMKPGFYH GHVSYLDFAK FGVKKKPIYI NVIRDPIERL VSYYYFLRFG 
       190        200        210        220        230        240 
DDYRPGLRRR KQGDKKTFDE CVAEGGSDCA PEKLWLQIPF FCGHSSECWN VGSRWAMDQA 
       250        260        270        280        290        300 
KYNLINEYFL VGVTEELEDF IMLLEAALPR FFRGATELYR TGKKSHLRKT TEKKLPTKQT 
       310        320        330        340        350    
IAKLQQSDIW KMENEFYEFA LEQFQFIRAH AVREKDGDLY ILAQNFFYEK IYPKSN



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q7LGA3-1-unknown MGLLRI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q7LGA3-1-unknown MGLLRI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77281

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)