Q7M6Y3: Phosphatidylinositol-binding clathrin assembly protein
Protein names | - Phosphatidylinositol-binding clathrin assembly protein - Clathrin assembly lymphoid myeloid leukemia - CALM |
---|---|
Gene names | Picalm |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q7M6Y3 |
5
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA
70 80 90 100 110 120
DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM
130 140 150 160 170 180
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD
190 200 210 220 230 240
FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF
250 260 270 280 290 300
LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT
310 320 330 340 350 360
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP
370 380 390 400 410 420
VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD
430 440 450 460 470 480
PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH
490 500 510 520 530 540
SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL
550 560 570 580 590 600
DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ
610 620 630 640 650 660
YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG PVSGAQIQFM
Isoforms
- Isoform 2 of Phosphatidylinositol-binding clathrin assembly protein - Isoform 3 of Phosphatidylinositol-binding clathrin assembly protein - Isoform 4 of Phosphatidylinositol-binding clathrin assembly protein - Isoform 5 of Phosphatidylinositol-binding clathrin assembly protein - Isoform 6 of Phosphatidylinositol-binding clathrin assembly proteinSequence View
10 20 30 40 50 60
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA
70 80 90 100 110 120
DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM
130 140 150 160 170 180
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD
190 200 210 220 230 240
FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF
250 260 270 280 290 300
LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT
310 320 330 340 350 360
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP
370 380 390 400 410 420
VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD
430 440 450 460 470 480
PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH
490 500 510 520 530 540
SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL
550 560 570 580 590 600
DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ
610 620 630 640 650 660
YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG PVSGAQIQFM
10 20 30 40 50 60
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA
70 80 90 100 110 120
DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM
130 140 150 160 170 180
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD
190 200 210 220 230 240
FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF
250 260 270 280 290 300
LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT
310 320 330 340 350 360
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP
370 380 390 400 410 420
VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD
430 440 450 460 470 480
PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH
490 500 510 520 530 540
SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL
550 560 570 580 590 600
DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ
610 620 630 640 650 660
YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG PVSGAQIQFM
10 20 30 40 50 60
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA
70 80 90 100 110 120
DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM
130 140 150 160 170 180
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD
190 200 210 220 230 240
FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF
250 260 270 280 290 300
LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT
310 320 330 340 350 360
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP
370 380 390 400 410 420
VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD
430 440 450 460 470 480
PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH
490 500 510 520 530 540
SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL
550 560 570 580 590 600
DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ
610 620 630 640 650 660
YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG PVSGAQIQFM
10 20 30 40 50 60
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA
70 80 90 100 110 120
DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM
130 140 150 160 170 180
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD
190 200 210 220 230 240
FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF
250 260 270 280 290 300
LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT
310 320 330 340 350 360
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP
370 380 390 400 410 420
VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD
430 440 450 460 470 480
PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH
490 500 510 520 530 540
SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL
550 560 570 580 590 600
DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ
610 620 630 640 650 660
YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG PVSGAQIQFM
10 20 30 40 50 60
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA
70 80 90 100 110 120
DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM
130 140 150 160 170 180
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD
190 200 210 220 230 240
FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF
250 260 270 280 290 300
LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT
310 320 330 340 350 360
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP
370 380 390 400 410 420
VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD
430 440 450 460 470 480
PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH
490 500 510 520 530 540
SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL
550 560 570 580 590 600
DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ
610 620 630 640 650 660
YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG PVSGAQIQFM
Protein Neighborhood
Domains & Features
5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q7M6Y3-2-unknown | MSGQSL... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
Q7M6Y3-2-unknown | MSGQSL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q7M6Y3-1-unknown | MSGQSL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85168 | |||
Q7M6Y3-1-unknown | MSGQSL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85169 | |||
Q7M6Y3-1-unknown | MSGQSL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85170 | |||
Q7M6Y3-1-unknown | MSGQSL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85171 | |||
Q7M6Y3-1-unknown | MSGQSL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85172 | |||
Q7M6Y3-2-Acetylation | SGQSLT... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q7M6Y3-2-Acetylation | SGQSLT... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110575 | ||
Q7M6Y3-2-Acetylation | SGQSLT... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110576 | ||
Q7M6Y3-2-Acetylation | SGQSLT... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110577 | ||
Q7M6Y3-2-Acetylation | SGQSLT... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110578 | ||
Q7M6Y3-2-Acetylation | SGQSLT... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110579 | ||
Q7M6Y3-2-Acetylation | SGQSLT... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
Q7M6Y3-251-unknown | LKVAEQ... | 251 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30661 | |||
Q7M6Y3-251-unknown | LKVAEQ... | 251 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148448 | |||
Q7M6Y3-251-unknown | LKVAEQ... | 251 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148449 | |||
Q7M6Y3-251-unknown | LKVAEQ... | 251 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148450 | |||
Q7M6Y3-251-unknown | LKVAEQ... | 251 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148451 | |||
Q7M6Y3-251-unknown | LKVAEQ... | 251 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148452 | |||
Q7M6Y3-283-unknown | ASLEGK... | 283 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30667 | |||
Q7M6Y3-283-unknown | ASLEGK... | 283 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149430 | |||
Q7M6Y3-283-unknown | ASLEGK... | 283 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149431 | |||
Q7M6Y3-283-unknown | ASLEGK... | 283 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149432 | |||
Q7M6Y3-283-unknown | ASLEGK... | 283 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149433 | |||
Q7M6Y3-283-unknown | ASLEGK... | 283 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149434 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...RISEFL | 250 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30661 | |||
...RISEFL | 250 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131821 | |||
...RISEFL | 250 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131822 | |||
...RISEFL | 250 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131823 | |||
...RISEFL | 250 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131824 | |||
...RISEFL | 250 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131825 | |||
...LEQHLA | 282 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30667 | |||
...LEQHLA | 282 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132815 | |||
...LEQHLA | 282 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132816 | |||
...LEQHLA | 282 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132817 | |||
...LEQHLA | 282 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132818 | |||
...LEQHLA | 282 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132819 | |||
...QIQFM | 660 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...QIQFM | 660 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt80786 | |||
...QIQFM | 660 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt80787 | |||
...QIQFM | 660 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt80788 | |||
...QIQFM | 660 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt80790 | |||
...QIQFM | 660 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt80789 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 250 | SEFL.|.LKVA | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> PICAL_MOUSE @250 | ||
CATE_MOUSE | 282 | QHLA.|.ASLE | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> PICAL_MOUSE @282 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|