Q7RTN6: STE20-related kinase adapter protein alpha

General Information

Protein names	- STE20-related kinase adapter protein alpha - STRAD alpha - STE20-related adapter protein - Serologically defined breast cancer antigen NY-BR-96
Gene names	STRADA
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7RTN6

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of STE20-related kinase adapter protein alpha - Isoform 3 of STE20-related kinase adapter protein alpha - Isoform 4 of STE20-related kinase adapter protein alpha - Isoform 5 of STE20-related kinase adapter protein alpha - Isoform 6 of STE20-related kinase adapter protein alpha

Sequence View

        10         20         30         40         50         60
MSFLVSKPER IRRWVSEKFI VEGLRDLELF GEQPPGDTRR KTNDASSESI ASFSKQEVMS
        70         80         90        100        110        120
SFLPEGGCYE LLTVIGKGFE DLMTVNLARY KPTGEYVTVR RINLEACSNE MVTFLQGELH
       130        140        150        160        170        180
VSKLFNHPNI VPYRATFIAD NELWVVTSFM AYGSAKDLIC THFMDGMNEL AIAYILQGVL
       190        200        210        220        230        240
KALDYIHHMG YVHRSVKASH ILISVDGKVY LSGLRSNLSM ISHGQRQRVV HDFPKYSVKV
       250        260        270        280        290        300
LPWLSPEVLQ QNLQGYDAKS DIYSVGITAC ELANGHVPFK DMPATQMLLE KLNGTVPCLL
       310        320        330        340        350        360
DTSTIPAEEL TMSPSRSVAN SGLSDSLTTS TPRPSNGDSP SHPYHRTFSP HFHHFVEQCL
       370        380        390        400        410        420
QRNPDARPSA STLLNHSFFK QIKRRASEAL PELLRPVTPI TNFEGSQSQD HSGIFGLVTN
       430
LEELEVDDWE F         10         20         30         40         50         60
MSFLVSKPER IRRWVSEKFI VEGLRDLELF GEQPPGDTRR KTNDASSESI ASFSKQEVMS
        70         80         90        100        110        120
SFLPEGGCYE LLTVIGKGFE DLMTVNLARY KPTGEYVTVR RINLEACSNE MVTFLQGELH
       130        140        150        160        170        180
VSKLFNHPNI VPYRATFIAD NELWVVTSFM AYGSAKDLIC THFMDGMNEL AIAYILQGVL
       190        200        210        220        230        240
KALDYIHHMG YVHRSVKASH ILISVDGKVY LSGLRSNLSM ISHGQRQRVV HDFPKYSVKV
       250        260        270        280        290        300
LPWLSPEVLQ QNLQGYDAKS DIYSVGITAC ELANGHVPFK DMPATQMLLE KLNGTVPCLL
       310        320        330        340        350        360
DTSTIPAEEL TMSPSRSVAN SGLSDSLTTS TPRPSNGDSP SHPYHRTFSP HFHHFVEQCL
       370        380        390        400        410        420
QRNPDARPSA STLLNHSFFK QIKRRASEAL PELLRPVTPI TNFEGSQSQD HSGIFGLVTN
       430
LEELEVDDWE F         10         20         30         40         50         60
MSFLVSKPER IRRWVSEKFI VEGLRDLELF GEQPPGDTRR KTNDASSESI ASFSKQEVMS
        70         80         90        100        110        120
SFLPEGGCYE LLTVIGKGFE DLMTVNLARY KPTGEYVTVR RINLEACSNE MVTFLQGELH
       130        140        150        160        170        180
VSKLFNHPNI VPYRATFIAD NELWVVTSFM AYGSAKDLIC THFMDGMNEL AIAYILQGVL
       190        200        210        220        230        240
KALDYIHHMG YVHRSVKASH ILISVDGKVY LSGLRSNLSM ISHGQRQRVV HDFPKYSVKV
       250        260        270        280        290        300
LPWLSPEVLQ QNLQGYDAKS DIYSVGITAC ELANGHVPFK DMPATQMLLE KLNGTVPCLL
       310        320        330        340        350        360
DTSTIPAEEL TMSPSRSVAN SGLSDSLTTS TPRPSNGDSP SHPYHRTFSP HFHHFVEQCL
       370        380        390        400        410        420
QRNPDARPSA STLLNHSFFK QIKRRASEAL PELLRPVTPI TNFEGSQSQD HSGIFGLVTN
       430
LEELEVDDWE F         10         20         30         40         50         60
MSFLVSKPER IRRWVSEKFI VEGLRDLELF GEQPPGDTRR KTNDASSESI ASFSKQEVMS
        70         80         90        100        110        120
SFLPEGGCYE LLTVIGKGFE DLMTVNLARY KPTGEYVTVR RINLEACSNE MVTFLQGELH
       130        140        150        160        170        180
VSKLFNHPNI VPYRATFIAD NELWVVTSFM AYGSAKDLIC THFMDGMNEL AIAYILQGVL
       190        200        210        220        230        240
KALDYIHHMG YVHRSVKASH ILISVDGKVY LSGLRSNLSM ISHGQRQRVV HDFPKYSVKV
       250        260        270        280        290        300
LPWLSPEVLQ QNLQGYDAKS DIYSVGITAC ELANGHVPFK DMPATQMLLE KLNGTVPCLL
       310        320        330        340        350        360
DTSTIPAEEL TMSPSRSVAN SGLSDSLTTS TPRPSNGDSP SHPYHRTFSP HFHHFVEQCL
       370        380        390        400        410        420
QRNPDARPSA STLLNHSFFK QIKRRASEAL PELLRPVTPI TNFEGSQSQD HSGIFGLVTN
       430
LEELEVDDWE F         10         20         30         40         50         60
MSFLVSKPER IRRWVSEKFI VEGLRDLELF GEQPPGDTRR KTNDASSESI ASFSKQEVMS
        70         80         90        100        110        120
SFLPEGGCYE LLTVIGKGFE DLMTVNLARY KPTGEYVTVR RINLEACSNE MVTFLQGELH
       130        140        150        160        170        180
VSKLFNHPNI VPYRATFIAD NELWVVTSFM AYGSAKDLIC THFMDGMNEL AIAYILQGVL
       190        200        210        220        230        240
KALDYIHHMG YVHRSVKASH ILISVDGKVY LSGLRSNLSM ISHGQRQRVV HDFPKYSVKV
       250        260        270        280        290        300
LPWLSPEVLQ QNLQGYDAKS DIYSVGITAC ELANGHVPFK DMPATQMLLE KLNGTVPCLL
       310        320        330        340        350        360
DTSTIPAEEL TMSPSRSVAN SGLSDSLTTS TPRPSNGDSP SHPYHRTFSP HFHHFVEQCL
       370        380        390        400        410        420
QRNPDARPSA STLLNHSFFK QIKRRASEAL PELLRPVTPI TNFEGSQSQD HSGIFGLVTN
       430
LEELEVDDWE F

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7RTN6-1-unknown	MSFLVS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7RTN6-1-unknown	MSFLVS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90968
Q7RTN6-2-acetylation	SFLVSK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q7RTN6-2-acetylation	SFLVSK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q7RTN6-2-acetylation	SFLVSK...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163011
Q7RTN6-59-unknown	MSSFLP...	59		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90969
Q7RTN6-59-unknown	MSSFLP...	59		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt100967
Q7RTN6-59-unknown	MSSFLP...	59		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt100968
Q7RTN6-59-unknown	MSSFLP...	59		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt100966

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DDWEF	431	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DDWEF	431	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86587
...DDWEF	431	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86585

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)