TopFIND 4.0

Q7TMB8: Cytoplasmic FMR1-interacting protein 1

General Information

Protein names
- Cytoplasmic FMR1-interacting protein 1
- Specifically Rac1-associated protein 1
- Sra-1
Gene names Cyfip1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q7TMB8

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAQVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSLLYQP NFNTNFEDRN AFVTGIARYI 
        70         80         90        100        110        120 
EQATVHSSMN EMLEEGQEYA VMLYTWRSCS RAIPQVKCNE QPNRVEIYEK TVEVLEPEVT 
       130        140        150        160        170        180 
KLMNFMYFQR NAIERFCGEV RRLCHAERRK DFVSEAYLIT LGKFINMFAV LDELKNMKCS 
       190        200        210        220        230        240 
VKNDHSAYKR AAQFLRKMAD PQSIQESQNL SMFLANHNKI TQSLQQQLEV ISGYEELLAD 
       250        260        270        280        290        300 
IVNLCVDYYE NRMYLTPSEK HMLLKVMGFG LYLMDGSVSN IYKLDAKKRI NLSKIDKYFK 
       310        320        330        340        350        360 
QLQVVPLFGD MQIELARYIK TSAHYEENKS RWTCASSSSS PQYNICEQMI QIREDHMRFI 
       370        380        390        400        410        420 
SELARYSNSE VVTGSGRQEA QKTDAEYRKL FDLALQGLQL LSQWSAHVME VYSWKLVHPT 
       430        440        450        460        470        480 
DKYSNKDCPD NAEEYERATR YNYTTEEKFA LVEVIAMIKG LQVLMGRMES VFNHAIRHTV 
       490        500        510        520        530        540 
YAALQDFSQV TLREPLRQAI KKKKNVIQSV LQAIRKTVCD WETGHEPFND PALRGEKDPK 
       550        560        570        580        590        600 
SGFDIKVPRR AVGPSSTQLY MVRTMLESLI ADKSGSKKTL RSSLEGPTIL DIEKFHRESF 
       610        620        630        640        650        660 
FYTHLINFSE TLQQCCDLSQ LWFREFFLEL TMGRRIQFPI EMSMPWILTD HILETKEASM 
       670        680        690        700        710        720 
MEYVLYSLDL YNDSAHYALT KFNKQFLYDE IEAEVNLCFD QFVYKLADQI FAYYKVMAGS 
       730        740        750        760        770        780 
LLLDKRLRSE CKNQGATIHL PPSNRYETLL KQRHVQLLGR SIDLNRLITQ RVSAAMYKSL 
       790        800        810        820        830        840 
ELAIGRFESE DLTSVVELDG LLEINRMTHK LLSRYLTLDS FDAMFREANH NVSAPYGRIT 
       850        860        870        880        890        900 
LHVFWELNYD FLPNYCYNGS TNRFVRTVLP FSQEFQRDKQ PNAQPQYLHG SKALNLAYSS 
       910        920        930        940        950        960 
IYGSYRNFVG PPHFQVICRL LGYQGIAVVM EELLKVVKSL LQGTILQYVK TLMEVMPKIC 
       970        980        990       1000       1010       1020 
RLPRHEYGSP GILEFFHHQL KDIVEYAELK TVCFQNLREV GNAVLFCLLI EQSLSLEEVC 
      1030       1040       1050       1060       1070       1080 
DLLHAAPFQN ILPRIHVKEG ERVDAKMKRL ESKYAPLHLV PLIERLGTPQ QIAIAREGDL 
      1090       1100       1110       1120       1130       1140 
LTKERLCCGL SMFEVILTRI RTFLDDPIWR GPLPSNGVMH VDECVEFHRL WSAMQFVYCI 
      1150       1160       1170       1180       1190       1200 
PVGTHEFTVE QCFGDGLHWA GCMIIVLLGQ QRRFAVLDFC YHLLKVQKHD GKDEIIKNVP 
      1210       1220       1230       1240       1250    
LKKMVERIRK FQILNDEIIT ILDKYLKSGD GESTPVEHVR CFQPPIHQSL ASS

Isoforms

- Isoform 2 of Cytoplasmic FMR1-interacting protein 1

Sequence View

        10         20         30         40         50         60 
MAAQVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSLLYQP NFNTNFEDRN AFVTGIARYI 
        70         80         90        100        110        120 
EQATVHSSMN EMLEEGQEYA VMLYTWRSCS RAIPQVKCNE QPNRVEIYEK TVEVLEPEVT 
       130        140        150        160        170        180 
KLMNFMYFQR NAIERFCGEV RRLCHAERRK DFVSEAYLIT LGKFINMFAV LDELKNMKCS 
       190        200        210        220        230        240 
VKNDHSAYKR AAQFLRKMAD PQSIQESQNL SMFLANHNKI TQSLQQQLEV ISGYEELLAD 
       250        260        270        280        290        300 
IVNLCVDYYE NRMYLTPSEK HMLLKVMGFG LYLMDGSVSN IYKLDAKKRI NLSKIDKYFK 
       310        320        330        340        350        360 
QLQVVPLFGD MQIELARYIK TSAHYEENKS RWTCASSSSS PQYNICEQMI QIREDHMRFI 
       370        380        390        400        410        420 
SELARYSNSE VVTGSGRQEA QKTDAEYRKL FDLALQGLQL LSQWSAHVME VYSWKLVHPT 
       430        440        450        460        470        480 
DKYSNKDCPD NAEEYERATR YNYTTEEKFA LVEVIAMIKG LQVLMGRMES VFNHAIRHTV 
       490        500        510        520        530        540 
YAALQDFSQV TLREPLRQAI KKKKNVIQSV LQAIRKTVCD WETGHEPFND PALRGEKDPK 
       550        560        570        580        590        600 
SGFDIKVPRR AVGPSSTQLY MVRTMLESLI ADKSGSKKTL RSSLEGPTIL DIEKFHRESF 
       610        620        630        640        650        660 
FYTHLINFSE TLQQCCDLSQ LWFREFFLEL TMGRRIQFPI EMSMPWILTD HILETKEASM 
       670        680        690        700        710        720 
MEYVLYSLDL YNDSAHYALT KFNKQFLYDE IEAEVNLCFD QFVYKLADQI FAYYKVMAGS 
       730        740        750        760        770        780 
LLLDKRLRSE CKNQGATIHL PPSNRYETLL KQRHVQLLGR SIDLNRLITQ RVSAAMYKSL 
       790        800        810        820        830        840 
ELAIGRFESE DLTSVVELDG LLEINRMTHK LLSRYLTLDS FDAMFREANH NVSAPYGRIT 
       850        860        870        880        890        900 
LHVFWELNYD FLPNYCYNGS TNRFVRTVLP FSQEFQRDKQ PNAQPQYLHG SKALNLAYSS 
       910        920        930        940        950        960 
IYGSYRNFVG PPHFQVICRL LGYQGIAVVM EELLKVVKSL LQGTILQYVK TLMEVMPKIC 
       970        980        990       1000       1010       1020 
RLPRHEYGSP GILEFFHHQL KDIVEYAELK TVCFQNLREV GNAVLFCLLI EQSLSLEEVC 
      1030       1040       1050       1060       1070       1080 
DLLHAAPFQN ILPRIHVKEG ERVDAKMKRL ESKYAPLHLV PLIERLGTPQ QIAIAREGDL 
      1090       1100       1110       1120       1130       1140 
LTKERLCCGL SMFEVILTRI RTFLDDPIWR GPLPSNGVMH VDECVEFHRL WSAMQFVYCI 
      1150       1160       1170       1180       1190       1200 
PVGTHEFTVE QCFGDGLHWA GCMIIVLLGQ QRRFAVLDFC YHLLKVQKHD GKDEIIKNVP 
      1210       1220       1230       1240       1250    
LKKMVERIRK FQILNDEIIT ILDKYLKSGD GESTPVEHVR CFQPPIHQSL ASS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q7TMB8-1-unknown MAAQVT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q7TMB8-1-unknown MAAQVT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt72238
    Q7TMB8-134-unknown ERFCGE... 134 inferred from electronic annotation unknown TISdb inferred from TISdb
    Q7TMB8-134-unknown ERFCGE... 134 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt197451

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)