TopFIND 4.0

Q7TNR9: Rho guanine nucleotide exchange factor 4

General Information

Protein names
- Rho guanine nucleotide exchange factor 4
- APC-stimulated guanine nucleotide exchange factor
- Asef
Gene names Arhgef4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q7TNR9

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDDQELGFKA GDVIEVMDAT NREWWWGRVA DGEGWFPASF VRLRVNQDEP ADDYEAPRAG 
        70         80         90        100        110        120 
AREADDSGPE AQSCKDQMRT NVINEILSTE RDYIKHLRDI CEGYVRQCRK REDMFSEEQL 
       130        140        150        160        170        180 
RTIFGNIEDI YRCQKAFVKA LEQKFNTERP HLSELGACFL EHQADFQIYS EYCNNHPNAC 
       190        200        210        220        230        240 
VELSRLTKLS KYVYFFEACR LLQRMIDISL DGFLLTPVQK ICKYPLQLAE LLKYTHPQHR 
       250        260        270        280        290        300 
DFKNVEAALH AMKNVAQLIN ERKRRLENID KIAQWQSSIE DWEGEDLLVR SSELIHSGEL 
       310        320        330        340        350        360 
TRVTQPQARS QQRMFFLFDR QLIYCKKDLL RRDVLYYKGR LDMDDLEVVD VEDGKDRDLH 
       370        380        390        400        410        420 
VSVKNAFRLY CGTTGDSHLL CARKPEQKQR WLKAFARERE QVRLDQETGF SITELQRKQA 
       430        440        450        460        470        480 
MLNASKQQAT GKPKAVGRPG YLTRHKHPSL PASRPQQQVL VLAEPRRKPS NFWHSISRLA 
   
PFRK

Isoforms



Sequence View



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q7TNR9-1-unknown MDDQEL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)