TopFIND 4.0

Q7TNV1: Ceramide synthase {ECO:0000305|PubMed:23275342}

General Information

Protein names
- Ceramide synthase {ECO:0000305|PubMed:23275342}
- 2.3.1.- {ECO:0000269|PubMed:23275342}
- Protein FAM57B
Gene names Fam57b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q7TNV1

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLTPMVAGGV VFPGLFLLSK NTLQRLPQLR WEEADAVIVS ARLVSSVQAI MASTAGYIVS 
        70         80         90        100        110        120 
TSCKHIIDDQ HWLSSAYTQF AVPYFIYDIY AMFLCHWHKH QVKGHGGEDG TPRALGSTWA 
       130        140        150        160        170        180 
VVRGYLHKEF LMVLHHAAMV LVCFPLSVVW RQGKGDFFLG CMLMAEVSTP FVCLGKILIQ 
       190        200        210        220        230        240 
YKQQHTLLHK VNGALMLLSF LCCRVLLFPY LYWAYGRHAG LPLLSVPMAI PAHVNLGAAL 
       250        260        270    
LLAPQLYWFF LICRGACRLF RPRGSPPPSP CQTQD

Isoforms

- Isoform 2 of Protein FAM57B - Isoform 3 of Protein FAM57B - Isoform 2 of Ceramide synthase - Isoform 3 of Ceramide synthase

Sequence View

        10         20         30         40         50         60 
MLTPMVAGGV VFPGLFLLSK NTLQRLPQLR WEEADAVIVS ARLVSSVQAI MASTAGYIVS 
        70         80         90        100        110        120 
TSCKHIIDDQ HWLSSAYTQF AVPYFIYDIY AMFLCHWHKH QVKGHGGEDG TPRALGSTWA 
       130        140        150        160        170        180 
VVRGYLHKEF LMVLHHAAMV LVCFPLSVVW RQGKGDFFLG CMLMAEVSTP FVCLGKILIQ 
       190        200        210        220        230        240 
YKQQHTLLHK VNGALMLLSF LCCRVLLFPY LYWAYGRHAG LPLLSVPMAI PAHVNLGAAL 
       250        260        270    
LLAPQLYWFF LICRGACRLF RPRGSPPPSP CQTQD         10         20         30         40         50         60 
MLTPMVAGGV VFPGLFLLSK NTLQRLPQLR WEEADAVIVS ARLVSSVQAI MASTAGYIVS 
        70         80         90        100        110        120 
TSCKHIIDDQ HWLSSAYTQF AVPYFIYDIY AMFLCHWHKH QVKGHGGEDG TPRALGSTWA 
       130        140        150        160        170        180 
VVRGYLHKEF LMVLHHAAMV LVCFPLSVVW RQGKGDFFLG CMLMAEVSTP FVCLGKILIQ 
       190        200        210        220        230        240 
YKQQHTLLHK VNGALMLLSF LCCRVLLFPY LYWAYGRHAG LPLLSVPMAI PAHVNLGAAL 
       250        260        270    
LLAPQLYWFF LICRGACRLF RPRGSPPPSP CQTQD         10         20         30         40         50         60 
MLTPMVAGGV VFPGLFLLSK NTLQRLPQLR WEEADAVIVS ARLVSSVQAI MASTAGYIVS 
        70         80         90        100        110        120 
TSCKHIIDDQ HWLSSAYTQF AVPYFIYDIY AMFLCHWHKH QVKGHGGEDG TPRALGSTWA 
       130        140        150        160        170        180 
VVRGYLHKEF LMVLHHAAMV LVCFPLSVVW RQGKGDFFLG CMLMAEVSTP FVCLGKILIQ 
       190        200        210        220        230        240 
YKQQHTLLHK VNGALMLLSF LCCRVLLFPY LYWAYGRHAG LPLLSVPMAI PAHVNLGAAL 
       250        260        270    
LLAPQLYWFF LICRGACRLF RPRGSPPPSP CQTQD         10         20         30         40         50         60 
MLTPMVAGGV VFPGLFLLSK NTLQRLPQLR WEEADAVIVS ARLVSSVQAI MASTAGYIVS 
        70         80         90        100        110        120 
TSCKHIIDDQ HWLSSAYTQF AVPYFIYDIY AMFLCHWHKH QVKGHGGEDG TPRALGSTWA 
       130        140        150        160        170        180 
VVRGYLHKEF LMVLHHAAMV LVCFPLSVVW RQGKGDFFLG CMLMAEVSTP FVCLGKILIQ 
       190        200        210        220        230        240 
YKQQHTLLHK VNGALMLLSF LCCRVLLFPY LYWAYGRHAG LPLLSVPMAI PAHVNLGAAL 
       250        260        270    
LLAPQLYWFF LICRGACRLF RPRGSPPPSP CQTQD



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Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q7TNV1-1-unknown MLTPMV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q7TNV1-51-unknown MASTAG... 51 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74637
    Q7TNV1-51-unknown MASTAG... 51 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt103868

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)