Q7TPH6: E3 ubiquitin-protein ligase MYCBP2 {ECO:0000305}
| Protein names | - E3 ubiquitin-protein ligase MYCBP2 {ECO:0000305} - 2.3.2.- {ECO:0000250|UniProtKB:O75592} - Myc-binding protein 2 {ECO:0000305} - Pam/highwire/rpm-1 protein {ECO:0000303|PubMed:14729956} - Protein Magellan {ECO:0000303|PubMed:18031680} - Protein associated with Myc {ECO:0000303|PubMed:14729956} |
|---|---|
| Gene names | Mycbp2 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q7TPH6 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MMMCAATASP AAASSGPGGD GFFAAATISS SPAPGALFMP VPDGSVAAAG LGLGLPTTDS
70 80 90 100 110 120
RGHYQLLLSG RALADRYRRI YTTALSDRDQ AGSSTGHPAS RNKKILNKKK LKRKQKSKSK
130 140 150 160 170 180
VKTRSKSENV ENTVIIPDIK LHSNPSAFNI YCNVRHCVLE WQKKETSLAA ASKNSVQSGE
190 200 210 220 230 240
SDSDEEEESR EPPIKLPKII EVGLCEVFEL IKETRFSHPS LCLRSLQALL NVLQGQQPEG
250 260 270 280 290 300
LQSEPPEVLE SLFQLLLEIT VRSTGMNDST GQSLTALSCA CLFSLVASWG ETGRTLQAIS
310 320 330 340 350 360
AILTNNGSHA CQTIQVPTIL NSLQRSVQAV LVGKIQVQDW FSNGIKKAAL MHKWPLKEVS
370 380 390 400 410 420
VDEDDQCLLQ NDGFFLYLLC KDGLYKIGSG YSGTVRGHIY NSTSRIRNRK EKKSWLGYAQ
430 440 450 460 470 480
GYLLYRDLNN HSMTAIRISP ETLEQDGTVL LPDCHTEGQN ILFTDGEYIN QIAASRDDGF
490 500 510 520 530 540
VVRIFATSTE PVLQQELQLK LARKCLHACG ISLFDLEKDL HIISTGFDEE SAILGAGREF
550 560 570 580 590 600
ALMKTANGKI YYTGKYQSLG IKQGGPSAGK WVELPITKSP KIVHFSVGHD GSHALLVAED
610 620 630 640 650 660
GSVFFTGSAS KGEDGESTKS RRQSKPYKPK KIIKMEGKIV VYTACNNGSS SVISKDGELY
670 680 690 700 710 720
MFGKDAIYSD SSSLVSDLKG HFVTQVAMGK AHTCVLMKNG EVWTFGVNNK GQCGRDTGAM
730 740 750 760 770 780
NQGGKGFGVE NMATAMDEDL EEELDEKDEK SMMCPPGMHK WKLEQCMVCT VCGDCTGYGA
790 800 810 820 830 840
SCVSSGRPDR VPGGICGCGS GESGCAVCGC CKACARELDG QEARQRGILD AVKEMIPLDL
850 860 870 880 890 900
LLAVPVPGVN IEEHLQLRQE EKRQRVIRRH RLEDGRGPLV FAGPIFMNHR EQALARLRSH
910 920 930 940 950 960
PAQLKHKRDK HKDGSGDRGE KDASKITTYP PGSVRFDCEL RAVQVSCGFH HSVVLMENGD
970 980 990 1000 1010 1020
VYTFGYGQHG QLGHGDVNSR GCPTLVQALP GPSTQVTAGS NHTAVLLMDG QVFTFGSFSK
1030 1040 1050 1060 1070 1080
GQLGRPILDI PYWNAKPAPM PNIGSKYGRK ATWIGASGDQ TFLRIDEALI NSHVLATSEI
1090 1100 1110 1120 1130 1140
FASKHIIGLV PASISEPPPF KCLLINKVDG SCKTFNDSEQ EDLQGFGVCL DPVYDVLWRF
1150 1160 1170 1180 1190 1200
RPSTRELWCY NAVVADARLP SATDMQSRCS ILSPELALPT GSRALTTRSH AALHILGCLD
1210 1220 1230 1240 1250 1260
TLAAMQDLKM GIASTEEETQ AVMKVYSKED YSVVNRFESH GGGWGYSAHS VEAIRFSADT
1270 1280 1290 1300 1310 1320
DILLGGLGLF GGRGEYTAKI KLFELGPDGG DHETDGDLLA ETDVLAYDCA AREKYAMMFD
1330 1340 1350 1360 1370 1380
EPVLLQAGWW YVAWARVSGP SSDCGSHGQA SITTDDGVIF QFKSSKKSNN GTDVNAGQIP
1390 1400 1410 1420 1430 1440
QLLYRLPTSD GSTSKGKQQT SEPVHILKRS FARTVSVECF ESLLSILHWS WTTLVLGVEE
1450 1460 1470 1480 1490 1500
LRGLKGFQFT ATLLDLERLR FVGTCCLRLL RVYTCEIYPV SATGKAVVEE TSKLAECIGK
1510 1520 1530 1540 1550 1560
TRTLLRKILS EGVDHCMVKL DNDPQGYLSQ PLRLLEAVLQ ECHNTFTACF HSFYPTPALQ
1570 1580 1590 1600 1610 1620
WACLCDLLNC LDQEANFKTS SSRLLAAVMS ALCHTSVKLT SLFPIAYDGE VLLRSIVKQV
1630 1640 1650 1660 1670 1680
STENDSTLVH RFPLLVGHME KLSQSEENIS GMTSFREVLE KMLVIVVLPV RNSLRRESEL
1690 1700 1710 1720 1730 1740
FSSHLVSNTC GLLASIVSEL TASALGSEVD GLNSLHSVKA SANRFTKTSQ GRSWNTGNGS
1750 1760 1770 1780 1790 1800
PDAICFAVDK PGIVVVGFAV YGGGGIHEYE LEVLVDDSEH AGDSTHSHRW TSLELVKGTY
1810 1820 1830 1840 1850 1860
TTDDSPSDIA EIRLDKVVPL KENVKYAVRL RNYGSRTANG DGGMTTVQCP DGVTFTFSTC
1870 1880 1890 1900 1910 1920
SLSSNGTNQT RGQIPQILYY RSEFDGDLQS QLLSKANEED KNCSRALSVV STVVRAAKDL
1930 1940 1950 1960 1970 1980
LHRALAVDAD DIPELLSSSS LFSMLLPLII AYIGPVAAAI PKVAVEVFGL VQQLLPSVAI
1990 2000 2010 2020 2030 2040
LNQKYAPPAF NPNQSTDSTT GNQPEQGLSA CTTSNHYAVI ESEHPYKPAC VMHYKVTFPE
2050 2060 2070 2080 2090 2100
CVRWMTIEFD PQCGTAQSED VIRLLIPVRT IQNSGYGAKL TSVHENLNSW VELKKYSGSS
2110 2120 2130 2140 2150 2160
GWPTMVLVLP GNEALFSLET ASDYVKDDKA SFYGFKCFAI GYEFSPGPDE GVIQLEKELA
2170 2180 2190 2200 2210 2220
NLGGVCAAAL MKKDLALPVG NELEEDLEIL EEAALQVCKT HSGILGKGLA LSHSPTILEA
2230 2240 2250 2260 2270 2280
LEGNLPLQIQ SNEQSFLDDF IACVPGSSGG RLARWLQPDS YADPQKTSLI LNKDDIRCGW
2290 2300 2310 2320 2330 2340
PTTITVQTKD QYGDVVHVPN MKVEVKAVPV SQKKTSLQQD QGKKCQRIPG SPSAAASSAD
2350 2360 2370 2380 2390 2400
MTFGGLASPK LDVSYEPMIV KEARYIAITM MKVYENYSFE ELRFASPTPK RPSENMLIRV
2410 2420 2430 2440 2450 2460
NNDGTYCANW TPGAIGLYTV HVTIDGIEID AGLEVKVKDP PKGMIPPGTQ LVKPKADPQP
2470 2480 2490 2500 2510 2520
NKIRKFVAKD SAGLRIRSHP SLQSEQIGIV RVNGTITFID EIHNDDGVWL RLNEETIKKY
2530 2540 2550 2560 2570 2580
VPNMNGYTEA WCLSFNQHLG KSLLVPVDNI FNASQGVRDL DVFSWTSKAF FPQEPKTNTD
2590 2600 2610 2620 2630 2640
DFFKDMNSCG PQEATMQERD HPFLRGGPGM YKVVKTGPSG HNIRSCPNLR GIPIGMLVLG
2650 2660 2670 2680 2690 2700
NKVKAVGEVT NSEGAWVQLD KNSMVEFCES DEGEAWSLAR DRGGNQYLRH EDEQVLLDQN
2710 2720 2730 2740 2750 2760
SQPPPPSPFS VQAFNKGASC SAQGFDYGLG NNKGDQLSAI LNSIQSRPNL PAPSIFDQAA
2770 2780 2790 2800 2810 2820
KPPSSLVHSP FVFGQPLSFQ QRQLQSDRGT ISTSSRPVST SGKSELPSKH SRSVKPDGHV
2830 2840 2850 2860 2870 2880
SRTPADQKKP RGTEGLSASE SLMLKSDAAK LRSDSHSRSL SPNHNTLQTL KSDGRTSSGF
2890 2900 2910 2920 2930 2940
RAESPGPGSR SSSPKPKPLP TPRSSPSGAS SPRSSSPQDK NLPQKSTAPA KTKLDPPRER
2950 2960 2970 2980 2990 3000
SKSDSYTLDP DTLRKKKMPL TEPLRGRSTS PKPKPVPKDP KDSPGSENRA PSPHVVQENL
3010 3020 3030 3040 3050 3060
HSEVVEVCTS STLKTNGVTD STCDDSGDLK SVDEGSNKVH FSIGKAPLKD EQEMRASPKI
3070 3080 3090 3100 3110 3120
SRKCANRHTR PKKEKSNFLF KGDGTKSLEP AKQAMSPSVA ECARAVFASF LWHEGIVHDA
3130 3140 3150 3160 3170 3180
MACSSFLKFN PDLSKEHAPI RSSLNSQPPT EEKEIKLKNR HSLEISSALN MFNIAPHGPD
3190 3200 3210 3220 3230 3240
ISKMGSINKN KVLSMLKEPP LHEKCEDGKS EATFEMSMHH TMKSKSPLPL TLQHLVAFWE
3250 3260 3270 3280 3290 3300
DISLATIKAA SQNMIFPSPG SCAVLKKKEC EKENKKTKKE KKKKEKTEIR PRGNLFGEMA
3310 3320 3330 3340 3350 3360
QLAVGGPEKD TICELCGESH PYPVTYHMRQ AHPGCGRYAG GQGYNSIGHF CGGWAGNCGD
3370 3380 3390 3400 3410 3420
GGMGGSTWYL VCDRCREKYL REKQAAAREK VKQSRRKPMQ VKTPRALPTM EAHQVIKANA
3430 3440 3450 3460 3470 3480
LFLLSLSSAA EPSILCYHPA KPFQSQLPIV KEGVSEDLPV KMPCLYLQTL ARHHHENFVG
3490 3500 3510 3520 3530 3540
YQDDNLFQDE MRYLRSTSVP APYISVTPDA SPNVFEEPES NMKSMPPSLE TSPITDTDLA
3550 3560 3570 3580 3590 3600
KRTVFQRSYS VVASEYDKQH SILPARVKAI PRRRVNSGDT VGSSLLRHPS PELSRLISAH
3610 3620 3630 3640 3650 3660
SSLSKGERNF QWPVLAFVIQ HHDLEGLEIA MKQALRKSAC RVFAMEAFNW LLCNVIQTTS
3670 3680 3690 3700 3710 3720
LHDILWHFVA ALTPSPVEAE EDEDEDNKSN KENAEQEKDT RVCEHPLSDI VIAGEAAHPL
3730 3740 3750 3760 3770 3780
PHTFHRLLQT ISDLMMSLPS GSSLQQMALR CWSLKFKQSD HQFLHQSNVF HHINNILSKS
3790 3800 3810 3820 3830 3840
DDGDSEESFS ISVQSGFEAM SQELCIVMCL KDLTSIVDIK TSSRPAMIGS LTDGSTETFW
3850 3860 3870 3880 3890 3900
ESGDEDKNKT KNITINCVKG INARYVSVHV DNSRDLGNKV TSMTFLTGKA VEELCRIKQV
3910 3920 3930 3940 3950 3960
DLDSRHIGWV TSELPGGDNQ IIKIELKGPE NTLRVRQVKV LGWKDGESTK IAGQISASVA
3970 3980 3990 4000 4010 4020
QQRSCEAETL RVFRLITSQV FGKLISGDAE PTPEQEEKAL LSSPEGEEKV YNATSDADLK
4030 4040 4050 4060 4070 4080
EHMVGIIFSR SKLTNLQKQV CAHIVQAIRM EATRVREEWE HAISSKENAN SQPSDEDASS
4090 4100 4110 4120 4130 4140
DAYCFELLSM VLALSGSNVG RQYLAQQLTL LQDLFSLLHT ASPRVQRQVT SLLRRVLPEV
4150 4160 4170 4180 4190 4200
TPNRLASIIG VKSLPPADIS DIIHSTEKGD WNKLGILDMF LGCIAKALTV QLKAKGTTIT
4210 4220 4230 4240 4250 4260
GTAGTTVGKG VTTVTLPMIF NSSYLRRGES HWWMKGSTPT QISEIIIRLI KDMAAGHLSE
4270 4280 4290 4300 4310 4320
AWSRVTKNAI AETIIALTKM EEEFRSPVRC IATTRLWLAL ASLCVLDQDH VDRLSSGRWM
4330 4340 4350 4360 4370 4380
GKDGQQKQMP MCDNHDDGET AAIILCNICG NLCTDCDRFL HLHRRTKTHQ RQVFKEEEEA
4390 4400 4410 4420 4430 4440
IKVDLHEGCG RTKLFWLMAL ADSKTMKAMV EFREHTGKPT TSSSEACRFC GSRSGTELSA
4450 4460 4470 4480 4490 4500
VGSVCSDADC QEYAKIACSK THPCGHPCGG VRNEEHCLPC LHGCDKSATT LKQDADDMCM
4510 4520 4530 4540 4550 4560
ICFTEALSAA PAIQLDCSHV FHLQCCRRVL ENRWLGPRIT FGFISCPICK NKINHIVLKD
4570 4580 4590 4600 4610 4620
LLDPIKELYE DVRRKALMRL EYEGLHKSEA ITTPGVRFYN DAAGYAMNRY AYYVCYKCRK
4630 4640 4650 4660 4670 4680
AYFGGEARCD AEAGQGDDYD PRELICGACS DVSRAQMCPK HGTDFLEYKC RYCCSVAVFF
4690 4700 4710 4720 4730 4740
CFGTTHFCNA CHDDFQRMTS IPKEELPHCP AGPKGKQLEG TECPLHVVHP PTGEEFALGC
GVCRNAHTF
Isoforms
- Isoform 2 of E3 ubiquitin-protein ligase MYCBP2 - Isoform 2 of E3 ubiquitin-protein ligase MYCBP2Sequence View
10 20 30 40 50 60
MMMCAATASP AAASSGPGGD GFFAAATISS SPAPGALFMP VPDGSVAAAG LGLGLPTTDS
70 80 90 100 110 120
RGHYQLLLSG RALADRYRRI YTTALSDRDQ AGSSTGHPAS RNKKILNKKK LKRKQKSKSK
130 140 150 160 170 180
VKTRSKSENV ENTVIIPDIK LHSNPSAFNI YCNVRHCVLE WQKKETSLAA ASKNSVQSGE
190 200 210 220 230 240
SDSDEEEESR EPPIKLPKII EVGLCEVFEL IKETRFSHPS LCLRSLQALL NVLQGQQPEG
250 260 270 280 290 300
LQSEPPEVLE SLFQLLLEIT VRSTGMNDST GQSLTALSCA CLFSLVASWG ETGRTLQAIS
310 320 330 340 350 360
AILTNNGSHA CQTIQVPTIL NSLQRSVQAV LVGKIQVQDW FSNGIKKAAL MHKWPLKEVS
370 380 390 400 410 420
VDEDDQCLLQ NDGFFLYLLC KDGLYKIGSG YSGTVRGHIY NSTSRIRNRK EKKSWLGYAQ
430 440 450 460 470 480
GYLLYRDLNN HSMTAIRISP ETLEQDGTVL LPDCHTEGQN ILFTDGEYIN QIAASRDDGF
490 500 510 520 530 540
VVRIFATSTE PVLQQELQLK LARKCLHACG ISLFDLEKDL HIISTGFDEE SAILGAGREF
550 560 570 580 590 600
ALMKTANGKI YYTGKYQSLG IKQGGPSAGK WVELPITKSP KIVHFSVGHD GSHALLVAED
610 620 630 640 650 660
GSVFFTGSAS KGEDGESTKS RRQSKPYKPK KIIKMEGKIV VYTACNNGSS SVISKDGELY
670 680 690 700 710 720
MFGKDAIYSD SSSLVSDLKG HFVTQVAMGK AHTCVLMKNG EVWTFGVNNK GQCGRDTGAM
730 740 750 760 770 780
NQGGKGFGVE NMATAMDEDL EEELDEKDEK SMMCPPGMHK WKLEQCMVCT VCGDCTGYGA
790 800 810 820 830 840
SCVSSGRPDR VPGGICGCGS GESGCAVCGC CKACARELDG QEARQRGILD AVKEMIPLDL
850 860 870 880 890 900
LLAVPVPGVN IEEHLQLRQE EKRQRVIRRH RLEDGRGPLV FAGPIFMNHR EQALARLRSH
910 920 930 940 950 960
PAQLKHKRDK HKDGSGDRGE KDASKITTYP PGSVRFDCEL RAVQVSCGFH HSVVLMENGD
970 980 990 1000 1010 1020
VYTFGYGQHG QLGHGDVNSR GCPTLVQALP GPSTQVTAGS NHTAVLLMDG QVFTFGSFSK
1030 1040 1050 1060 1070 1080
GQLGRPILDI PYWNAKPAPM PNIGSKYGRK ATWIGASGDQ TFLRIDEALI NSHVLATSEI
1090 1100 1110 1120 1130 1140
FASKHIIGLV PASISEPPPF KCLLINKVDG SCKTFNDSEQ EDLQGFGVCL DPVYDVLWRF
1150 1160 1170 1180 1190 1200
RPSTRELWCY NAVVADARLP SATDMQSRCS ILSPELALPT GSRALTTRSH AALHILGCLD
1210 1220 1230 1240 1250 1260
TLAAMQDLKM GIASTEEETQ AVMKVYSKED YSVVNRFESH GGGWGYSAHS VEAIRFSADT
1270 1280 1290 1300 1310 1320
DILLGGLGLF GGRGEYTAKI KLFELGPDGG DHETDGDLLA ETDVLAYDCA AREKYAMMFD
1330 1340 1350 1360 1370 1380
EPVLLQAGWW YVAWARVSGP SSDCGSHGQA SITTDDGVIF QFKSSKKSNN GTDVNAGQIP
1390 1400 1410 1420 1430 1440
QLLYRLPTSD GSTSKGKQQT SEPVHILKRS FARTVSVECF ESLLSILHWS WTTLVLGVEE
1450 1460 1470 1480 1490 1500
LRGLKGFQFT ATLLDLERLR FVGTCCLRLL RVYTCEIYPV SATGKAVVEE TSKLAECIGK
1510 1520 1530 1540 1550 1560
TRTLLRKILS EGVDHCMVKL DNDPQGYLSQ PLRLLEAVLQ ECHNTFTACF HSFYPTPALQ
1570 1580 1590 1600 1610 1620
WACLCDLLNC LDQEANFKTS SSRLLAAVMS ALCHTSVKLT SLFPIAYDGE VLLRSIVKQV
1630 1640 1650 1660 1670 1680
STENDSTLVH RFPLLVGHME KLSQSEENIS GMTSFREVLE KMLVIVVLPV RNSLRRESEL
1690 1700 1710 1720 1730 1740
FSSHLVSNTC GLLASIVSEL TASALGSEVD GLNSLHSVKA SANRFTKTSQ GRSWNTGNGS
1750 1760 1770 1780 1790 1800
PDAICFAVDK PGIVVVGFAV YGGGGIHEYE LEVLVDDSEH AGDSTHSHRW TSLELVKGTY
1810 1820 1830 1840 1850 1860
TTDDSPSDIA EIRLDKVVPL KENVKYAVRL RNYGSRTANG DGGMTTVQCP DGVTFTFSTC
1870 1880 1890 1900 1910 1920
SLSSNGTNQT RGQIPQILYY RSEFDGDLQS QLLSKANEED KNCSRALSVV STVVRAAKDL
1930 1940 1950 1960 1970 1980
LHRALAVDAD DIPELLSSSS LFSMLLPLII AYIGPVAAAI PKVAVEVFGL VQQLLPSVAI
1990 2000 2010 2020 2030 2040
LNQKYAPPAF NPNQSTDSTT GNQPEQGLSA CTTSNHYAVI ESEHPYKPAC VMHYKVTFPE
2050 2060 2070 2080 2090 2100
CVRWMTIEFD PQCGTAQSED VIRLLIPVRT IQNSGYGAKL TSVHENLNSW VELKKYSGSS
2110 2120 2130 2140 2150 2160
GWPTMVLVLP GNEALFSLET ASDYVKDDKA SFYGFKCFAI GYEFSPGPDE GVIQLEKELA
2170 2180 2190 2200 2210 2220
NLGGVCAAAL MKKDLALPVG NELEEDLEIL EEAALQVCKT HSGILGKGLA LSHSPTILEA
2230 2240 2250 2260 2270 2280
LEGNLPLQIQ SNEQSFLDDF IACVPGSSGG RLARWLQPDS YADPQKTSLI LNKDDIRCGW
2290 2300 2310 2320 2330 2340
PTTITVQTKD QYGDVVHVPN MKVEVKAVPV SQKKTSLQQD QGKKCQRIPG SPSAAASSAD
2350 2360 2370 2380 2390 2400
MTFGGLASPK LDVSYEPMIV KEARYIAITM MKVYENYSFE ELRFASPTPK RPSENMLIRV
2410 2420 2430 2440 2450 2460
NNDGTYCANW TPGAIGLYTV HVTIDGIEID AGLEVKVKDP PKGMIPPGTQ LVKPKADPQP
2470 2480 2490 2500 2510 2520
NKIRKFVAKD SAGLRIRSHP SLQSEQIGIV RVNGTITFID EIHNDDGVWL RLNEETIKKY
2530 2540 2550 2560 2570 2580
VPNMNGYTEA WCLSFNQHLG KSLLVPVDNI FNASQGVRDL DVFSWTSKAF FPQEPKTNTD
2590 2600 2610 2620 2630 2640
DFFKDMNSCG PQEATMQERD HPFLRGGPGM YKVVKTGPSG HNIRSCPNLR GIPIGMLVLG
2650 2660 2670 2680 2690 2700
NKVKAVGEVT NSEGAWVQLD KNSMVEFCES DEGEAWSLAR DRGGNQYLRH EDEQVLLDQN
2710 2720 2730 2740 2750 2760
SQPPPPSPFS VQAFNKGASC SAQGFDYGLG NNKGDQLSAI LNSIQSRPNL PAPSIFDQAA
2770 2780 2790 2800 2810 2820
KPPSSLVHSP FVFGQPLSFQ QRQLQSDRGT ISTSSRPVST SGKSELPSKH SRSVKPDGHV
2830 2840 2850 2860 2870 2880
SRTPADQKKP RGTEGLSASE SLMLKSDAAK LRSDSHSRSL SPNHNTLQTL KSDGRTSSGF
2890 2900 2910 2920 2930 2940
RAESPGPGSR SSSPKPKPLP TPRSSPSGAS SPRSSSPQDK NLPQKSTAPA KTKLDPPRER
2950 2960 2970 2980 2990 3000
SKSDSYTLDP DTLRKKKMPL TEPLRGRSTS PKPKPVPKDP KDSPGSENRA PSPHVVQENL
3010 3020 3030 3040 3050 3060
HSEVVEVCTS STLKTNGVTD STCDDSGDLK SVDEGSNKVH FSIGKAPLKD EQEMRASPKI
3070 3080 3090 3100 3110 3120
SRKCANRHTR PKKEKSNFLF KGDGTKSLEP AKQAMSPSVA ECARAVFASF LWHEGIVHDA
3130 3140 3150 3160 3170 3180
MACSSFLKFN PDLSKEHAPI RSSLNSQPPT EEKEIKLKNR HSLEISSALN MFNIAPHGPD
3190 3200 3210 3220 3230 3240
ISKMGSINKN KVLSMLKEPP LHEKCEDGKS EATFEMSMHH TMKSKSPLPL TLQHLVAFWE
3250 3260 3270 3280 3290 3300
DISLATIKAA SQNMIFPSPG SCAVLKKKEC EKENKKTKKE KKKKEKTEIR PRGNLFGEMA
3310 3320 3330 3340 3350 3360
QLAVGGPEKD TICELCGESH PYPVTYHMRQ AHPGCGRYAG GQGYNSIGHF CGGWAGNCGD
3370 3380 3390 3400 3410 3420
GGMGGSTWYL VCDRCREKYL REKQAAAREK VKQSRRKPMQ VKTPRALPTM EAHQVIKANA
3430 3440 3450 3460 3470 3480
LFLLSLSSAA EPSILCYHPA KPFQSQLPIV KEGVSEDLPV KMPCLYLQTL ARHHHENFVG
3490 3500 3510 3520 3530 3540
YQDDNLFQDE MRYLRSTSVP APYISVTPDA SPNVFEEPES NMKSMPPSLE TSPITDTDLA
3550 3560 3570 3580 3590 3600
KRTVFQRSYS VVASEYDKQH SILPARVKAI PRRRVNSGDT VGSSLLRHPS PELSRLISAH
3610 3620 3630 3640 3650 3660
SSLSKGERNF QWPVLAFVIQ HHDLEGLEIA MKQALRKSAC RVFAMEAFNW LLCNVIQTTS
3670 3680 3690 3700 3710 3720
LHDILWHFVA ALTPSPVEAE EDEDEDNKSN KENAEQEKDT RVCEHPLSDI VIAGEAAHPL
3730 3740 3750 3760 3770 3780
PHTFHRLLQT ISDLMMSLPS GSSLQQMALR CWSLKFKQSD HQFLHQSNVF HHINNILSKS
3790 3800 3810 3820 3830 3840
DDGDSEESFS ISVQSGFEAM SQELCIVMCL KDLTSIVDIK TSSRPAMIGS LTDGSTETFW
3850 3860 3870 3880 3890 3900
ESGDEDKNKT KNITINCVKG INARYVSVHV DNSRDLGNKV TSMTFLTGKA VEELCRIKQV
3910 3920 3930 3940 3950 3960
DLDSRHIGWV TSELPGGDNQ IIKIELKGPE NTLRVRQVKV LGWKDGESTK IAGQISASVA
3970 3980 3990 4000 4010 4020
QQRSCEAETL RVFRLITSQV FGKLISGDAE PTPEQEEKAL LSSPEGEEKV YNATSDADLK
4030 4040 4050 4060 4070 4080
EHMVGIIFSR SKLTNLQKQV CAHIVQAIRM EATRVREEWE HAISSKENAN SQPSDEDASS
4090 4100 4110 4120 4130 4140
DAYCFELLSM VLALSGSNVG RQYLAQQLTL LQDLFSLLHT ASPRVQRQVT SLLRRVLPEV
4150 4160 4170 4180 4190 4200
TPNRLASIIG VKSLPPADIS DIIHSTEKGD WNKLGILDMF LGCIAKALTV QLKAKGTTIT
4210 4220 4230 4240 4250 4260
GTAGTTVGKG VTTVTLPMIF NSSYLRRGES HWWMKGSTPT QISEIIIRLI KDMAAGHLSE
4270 4280 4290 4300 4310 4320
AWSRVTKNAI AETIIALTKM EEEFRSPVRC IATTRLWLAL ASLCVLDQDH VDRLSSGRWM
4330 4340 4350 4360 4370 4380
GKDGQQKQMP MCDNHDDGET AAIILCNICG NLCTDCDRFL HLHRRTKTHQ RQVFKEEEEA
4390 4400 4410 4420 4430 4440
IKVDLHEGCG RTKLFWLMAL ADSKTMKAMV EFREHTGKPT TSSSEACRFC GSRSGTELSA
4450 4460 4470 4480 4490 4500
VGSVCSDADC QEYAKIACSK THPCGHPCGG VRNEEHCLPC LHGCDKSATT LKQDADDMCM
4510 4520 4530 4540 4550 4560
ICFTEALSAA PAIQLDCSHV FHLQCCRRVL ENRWLGPRIT FGFISCPICK NKINHIVLKD
4570 4580 4590 4600 4610 4620
LLDPIKELYE DVRRKALMRL EYEGLHKSEA ITTPGVRFYN DAAGYAMNRY AYYVCYKCRK
4630 4640 4650 4660 4670 4680
AYFGGEARCD AEAGQGDDYD PRELICGACS DVSRAQMCPK HGTDFLEYKC RYCCSVAVFF
4690 4700 4710 4720 4730 4740
CFGTTHFCNA CHDDFQRMTS IPKEELPHCP AGPKGKQLEG TECPLHVVHP PTGEEFALGC
GVCRNAHTF
10 20 30 40 50 60
MMMCAATASP AAASSGPGGD GFFAAATISS SPAPGALFMP VPDGSVAAAG LGLGLPTTDS
70 80 90 100 110 120
RGHYQLLLSG RALADRYRRI YTTALSDRDQ AGSSTGHPAS RNKKILNKKK LKRKQKSKSK
130 140 150 160 170 180
VKTRSKSENV ENTVIIPDIK LHSNPSAFNI YCNVRHCVLE WQKKETSLAA ASKNSVQSGE
190 200 210 220 230 240
SDSDEEEESR EPPIKLPKII EVGLCEVFEL IKETRFSHPS LCLRSLQALL NVLQGQQPEG
250 260 270 280 290 300
LQSEPPEVLE SLFQLLLEIT VRSTGMNDST GQSLTALSCA CLFSLVASWG ETGRTLQAIS
310 320 330 340 350 360
AILTNNGSHA CQTIQVPTIL NSLQRSVQAV LVGKIQVQDW FSNGIKKAAL MHKWPLKEVS
370 380 390 400 410 420
VDEDDQCLLQ NDGFFLYLLC KDGLYKIGSG YSGTVRGHIY NSTSRIRNRK EKKSWLGYAQ
430 440 450 460 470 480
GYLLYRDLNN HSMTAIRISP ETLEQDGTVL LPDCHTEGQN ILFTDGEYIN QIAASRDDGF
490 500 510 520 530 540
VVRIFATSTE PVLQQELQLK LARKCLHACG ISLFDLEKDL HIISTGFDEE SAILGAGREF
550 560 570 580 590 600
ALMKTANGKI YYTGKYQSLG IKQGGPSAGK WVELPITKSP KIVHFSVGHD GSHALLVAED
610 620 630 640 650 660
GSVFFTGSAS KGEDGESTKS RRQSKPYKPK KIIKMEGKIV VYTACNNGSS SVISKDGELY
670 680 690 700 710 720
MFGKDAIYSD SSSLVSDLKG HFVTQVAMGK AHTCVLMKNG EVWTFGVNNK GQCGRDTGAM
730 740 750 760 770 780
NQGGKGFGVE NMATAMDEDL EEELDEKDEK SMMCPPGMHK WKLEQCMVCT VCGDCTGYGA
790 800 810 820 830 840
SCVSSGRPDR VPGGICGCGS GESGCAVCGC CKACARELDG QEARQRGILD AVKEMIPLDL
850 860 870 880 890 900
LLAVPVPGVN IEEHLQLRQE EKRQRVIRRH RLEDGRGPLV FAGPIFMNHR EQALARLRSH
910 920 930 940 950 960
PAQLKHKRDK HKDGSGDRGE KDASKITTYP PGSVRFDCEL RAVQVSCGFH HSVVLMENGD
970 980 990 1000 1010 1020
VYTFGYGQHG QLGHGDVNSR GCPTLVQALP GPSTQVTAGS NHTAVLLMDG QVFTFGSFSK
1030 1040 1050 1060 1070 1080
GQLGRPILDI PYWNAKPAPM PNIGSKYGRK ATWIGASGDQ TFLRIDEALI NSHVLATSEI
1090 1100 1110 1120 1130 1140
FASKHIIGLV PASISEPPPF KCLLINKVDG SCKTFNDSEQ EDLQGFGVCL DPVYDVLWRF
1150 1160 1170 1180 1190 1200
RPSTRELWCY NAVVADARLP SATDMQSRCS ILSPELALPT GSRALTTRSH AALHILGCLD
1210 1220 1230 1240 1250 1260
TLAAMQDLKM GIASTEEETQ AVMKVYSKED YSVVNRFESH GGGWGYSAHS VEAIRFSADT
1270 1280 1290 1300 1310 1320
DILLGGLGLF GGRGEYTAKI KLFELGPDGG DHETDGDLLA ETDVLAYDCA AREKYAMMFD
1330 1340 1350 1360 1370 1380
EPVLLQAGWW YVAWARVSGP SSDCGSHGQA SITTDDGVIF QFKSSKKSNN GTDVNAGQIP
1390 1400 1410 1420 1430 1440
QLLYRLPTSD GSTSKGKQQT SEPVHILKRS FARTVSVECF ESLLSILHWS WTTLVLGVEE
1450 1460 1470 1480 1490 1500
LRGLKGFQFT ATLLDLERLR FVGTCCLRLL RVYTCEIYPV SATGKAVVEE TSKLAECIGK
1510 1520 1530 1540 1550 1560
TRTLLRKILS EGVDHCMVKL DNDPQGYLSQ PLRLLEAVLQ ECHNTFTACF HSFYPTPALQ
1570 1580 1590 1600 1610 1620
WACLCDLLNC LDQEANFKTS SSRLLAAVMS ALCHTSVKLT SLFPIAYDGE VLLRSIVKQV
1630 1640 1650 1660 1670 1680
STENDSTLVH RFPLLVGHME KLSQSEENIS GMTSFREVLE KMLVIVVLPV RNSLRRESEL
1690 1700 1710 1720 1730 1740
FSSHLVSNTC GLLASIVSEL TASALGSEVD GLNSLHSVKA SANRFTKTSQ GRSWNTGNGS
1750 1760 1770 1780 1790 1800
PDAICFAVDK PGIVVVGFAV YGGGGIHEYE LEVLVDDSEH AGDSTHSHRW TSLELVKGTY
1810 1820 1830 1840 1850 1860
TTDDSPSDIA EIRLDKVVPL KENVKYAVRL RNYGSRTANG DGGMTTVQCP DGVTFTFSTC
1870 1880 1890 1900 1910 1920
SLSSNGTNQT RGQIPQILYY RSEFDGDLQS QLLSKANEED KNCSRALSVV STVVRAAKDL
1930 1940 1950 1960 1970 1980
LHRALAVDAD DIPELLSSSS LFSMLLPLII AYIGPVAAAI PKVAVEVFGL VQQLLPSVAI
1990 2000 2010 2020 2030 2040
LNQKYAPPAF NPNQSTDSTT GNQPEQGLSA CTTSNHYAVI ESEHPYKPAC VMHYKVTFPE
2050 2060 2070 2080 2090 2100
CVRWMTIEFD PQCGTAQSED VIRLLIPVRT IQNSGYGAKL TSVHENLNSW VELKKYSGSS
2110 2120 2130 2140 2150 2160
GWPTMVLVLP GNEALFSLET ASDYVKDDKA SFYGFKCFAI GYEFSPGPDE GVIQLEKELA
2170 2180 2190 2200 2210 2220
NLGGVCAAAL MKKDLALPVG NELEEDLEIL EEAALQVCKT HSGILGKGLA LSHSPTILEA
2230 2240 2250 2260 2270 2280
LEGNLPLQIQ SNEQSFLDDF IACVPGSSGG RLARWLQPDS YADPQKTSLI LNKDDIRCGW
2290 2300 2310 2320 2330 2340
PTTITVQTKD QYGDVVHVPN MKVEVKAVPV SQKKTSLQQD QGKKCQRIPG SPSAAASSAD
2350 2360 2370 2380 2390 2400
MTFGGLASPK LDVSYEPMIV KEARYIAITM MKVYENYSFE ELRFASPTPK RPSENMLIRV
2410 2420 2430 2440 2450 2460
NNDGTYCANW TPGAIGLYTV HVTIDGIEID AGLEVKVKDP PKGMIPPGTQ LVKPKADPQP
2470 2480 2490 2500 2510 2520
NKIRKFVAKD SAGLRIRSHP SLQSEQIGIV RVNGTITFID EIHNDDGVWL RLNEETIKKY
2530 2540 2550 2560 2570 2580
VPNMNGYTEA WCLSFNQHLG KSLLVPVDNI FNASQGVRDL DVFSWTSKAF FPQEPKTNTD
2590 2600 2610 2620 2630 2640
DFFKDMNSCG PQEATMQERD HPFLRGGPGM YKVVKTGPSG HNIRSCPNLR GIPIGMLVLG
2650 2660 2670 2680 2690 2700
NKVKAVGEVT NSEGAWVQLD KNSMVEFCES DEGEAWSLAR DRGGNQYLRH EDEQVLLDQN
2710 2720 2730 2740 2750 2760
SQPPPPSPFS VQAFNKGASC SAQGFDYGLG NNKGDQLSAI LNSIQSRPNL PAPSIFDQAA
2770 2780 2790 2800 2810 2820
KPPSSLVHSP FVFGQPLSFQ QRQLQSDRGT ISTSSRPVST SGKSELPSKH SRSVKPDGHV
2830 2840 2850 2860 2870 2880
SRTPADQKKP RGTEGLSASE SLMLKSDAAK LRSDSHSRSL SPNHNTLQTL KSDGRTSSGF
2890 2900 2910 2920 2930 2940
RAESPGPGSR SSSPKPKPLP TPRSSPSGAS SPRSSSPQDK NLPQKSTAPA KTKLDPPRER
2950 2960 2970 2980 2990 3000
SKSDSYTLDP DTLRKKKMPL TEPLRGRSTS PKPKPVPKDP KDSPGSENRA PSPHVVQENL
3010 3020 3030 3040 3050 3060
HSEVVEVCTS STLKTNGVTD STCDDSGDLK SVDEGSNKVH FSIGKAPLKD EQEMRASPKI
3070 3080 3090 3100 3110 3120
SRKCANRHTR PKKEKSNFLF KGDGTKSLEP AKQAMSPSVA ECARAVFASF LWHEGIVHDA
3130 3140 3150 3160 3170 3180
MACSSFLKFN PDLSKEHAPI RSSLNSQPPT EEKEIKLKNR HSLEISSALN MFNIAPHGPD
3190 3200 3210 3220 3230 3240
ISKMGSINKN KVLSMLKEPP LHEKCEDGKS EATFEMSMHH TMKSKSPLPL TLQHLVAFWE
3250 3260 3270 3280 3290 3300
DISLATIKAA SQNMIFPSPG SCAVLKKKEC EKENKKTKKE KKKKEKTEIR PRGNLFGEMA
3310 3320 3330 3340 3350 3360
QLAVGGPEKD TICELCGESH PYPVTYHMRQ AHPGCGRYAG GQGYNSIGHF CGGWAGNCGD
3370 3380 3390 3400 3410 3420
GGMGGSTWYL VCDRCREKYL REKQAAAREK VKQSRRKPMQ VKTPRALPTM EAHQVIKANA
3430 3440 3450 3460 3470 3480
LFLLSLSSAA EPSILCYHPA KPFQSQLPIV KEGVSEDLPV KMPCLYLQTL ARHHHENFVG
3490 3500 3510 3520 3530 3540
YQDDNLFQDE MRYLRSTSVP APYISVTPDA SPNVFEEPES NMKSMPPSLE TSPITDTDLA
3550 3560 3570 3580 3590 3600
KRTVFQRSYS VVASEYDKQH SILPARVKAI PRRRVNSGDT VGSSLLRHPS PELSRLISAH
3610 3620 3630 3640 3650 3660
SSLSKGERNF QWPVLAFVIQ HHDLEGLEIA MKQALRKSAC RVFAMEAFNW LLCNVIQTTS
3670 3680 3690 3700 3710 3720
LHDILWHFVA ALTPSPVEAE EDEDEDNKSN KENAEQEKDT RVCEHPLSDI VIAGEAAHPL
3730 3740 3750 3760 3770 3780
PHTFHRLLQT ISDLMMSLPS GSSLQQMALR CWSLKFKQSD HQFLHQSNVF HHINNILSKS
3790 3800 3810 3820 3830 3840
DDGDSEESFS ISVQSGFEAM SQELCIVMCL KDLTSIVDIK TSSRPAMIGS LTDGSTETFW
3850 3860 3870 3880 3890 3900
ESGDEDKNKT KNITINCVKG INARYVSVHV DNSRDLGNKV TSMTFLTGKA VEELCRIKQV
3910 3920 3930 3940 3950 3960
DLDSRHIGWV TSELPGGDNQ IIKIELKGPE NTLRVRQVKV LGWKDGESTK IAGQISASVA
3970 3980 3990 4000 4010 4020
QQRSCEAETL RVFRLITSQV FGKLISGDAE PTPEQEEKAL LSSPEGEEKV YNATSDADLK
4030 4040 4050 4060 4070 4080
EHMVGIIFSR SKLTNLQKQV CAHIVQAIRM EATRVREEWE HAISSKENAN SQPSDEDASS
4090 4100 4110 4120 4130 4140
DAYCFELLSM VLALSGSNVG RQYLAQQLTL LQDLFSLLHT ASPRVQRQVT SLLRRVLPEV
4150 4160 4170 4180 4190 4200
TPNRLASIIG VKSLPPADIS DIIHSTEKGD WNKLGILDMF LGCIAKALTV QLKAKGTTIT
4210 4220 4230 4240 4250 4260
GTAGTTVGKG VTTVTLPMIF NSSYLRRGES HWWMKGSTPT QISEIIIRLI KDMAAGHLSE
4270 4280 4290 4300 4310 4320
AWSRVTKNAI AETIIALTKM EEEFRSPVRC IATTRLWLAL ASLCVLDQDH VDRLSSGRWM
4330 4340 4350 4360 4370 4380
GKDGQQKQMP MCDNHDDGET AAIILCNICG NLCTDCDRFL HLHRRTKTHQ RQVFKEEEEA
4390 4400 4410 4420 4430 4440
IKVDLHEGCG RTKLFWLMAL ADSKTMKAMV EFREHTGKPT TSSSEACRFC GSRSGTELSA
4450 4460 4470 4480 4490 4500
VGSVCSDADC QEYAKIACSK THPCGHPCGG VRNEEHCLPC LHGCDKSATT LKQDADDMCM
4510 4520 4530 4540 4550 4560
ICFTEALSAA PAIQLDCSHV FHLQCCRRVL ENRWLGPRIT FGFISCPICK NKINHIVLKD
4570 4580 4590 4600 4610 4620
LLDPIKELYE DVRRKALMRL EYEGLHKSEA ITTPGVRFYN DAAGYAMNRY AYYVCYKCRK
4630 4640 4650 4660 4670 4680
AYFGGEARCD AEAGQGDDYD PRELICGACS DVSRAQMCPK HGTDFLEYKC RYCCSVAVFF
4690 4700 4710 4720 4730 4740
CFGTTHFCNA CHDDFQRMTS IPKEELPHCP AGPKGKQLEG TECPLHVVHP PTGEEFALGC
GVCRNAHTF
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q7TPH6-1-unknown | MMMCAA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q7TPH6-1-unknown | MMMCAA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt81929 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...PHCPAG | 4711 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...PHCPAG | 4711 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt77547 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|