TopFIND 4.0

Q7TQ32: Hemojuvelin {ECO:0000305}

General Information

Protein names
- Hemojuvelin {ECO:0000305}
- Hemochromatosis type 2 protein homolog
- Hemojuvelin BMP coreceptor {ECO:0000305}
- RGM domain family member C
Gene names Hfe2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q7TQ32

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGQSPSPRSP HGSPPTLSTL TLLLLLCGQA HSQCKILRCN AEYVSSTLSL RGGGSPDTPR 
        70         80         90        100        110        120 
GGGRGGLASG GLCRALRSYA LCTRRTARTC RGDLAFHSAV HGIEDLMIQH NCSRQGPTAP 
       130        140        150        160        170        180 
PPARGPALPG AGPAPLTPDP CDYEARFSRL HGRAPGFLHC ASFGDPHVRS FHNQFHTCRV 
       190        200        210        220        230        240 
QGAWPLLDND FLFVQATSSP VSSGANATTI RKITIIFKNM QECIDQKVYQ AEVDNLPAAF 
       250        260        270        280        290        300 
EDGSINGGDR PGGSSLSIQT ANLGSHVEIR AAYIGTTIII RQTAGQLSFS IRVAEDVARA 
       310        320        330        340        350        360 
FSAEQDLQLC VGGCPPSQRL SRSERNRRGA IAIDTARRLC KEGLPVEDAY FQSCVFDVSV 
       370        380        390        400        410        420 
SGDPNFTVAA QTALDDARIF LTDLENLHLF PSDAGPPLSP AICLVPLLSA LFVLWLCFSK 
   

Isoforms

- Isoform 2 of Hemojuvelin

Sequence View

        10         20         30         40         50         60 
MGQSPSPRSP HGSPPTLSTL TLLLLLCGQA HSQCKILRCN AEYVSSTLSL RGGGSPDTPR 
        70         80         90        100        110        120 
GGGRGGLASG GLCRALRSYA LCTRRTARTC RGDLAFHSAV HGIEDLMIQH NCSRQGPTAP 
       130        140        150        160        170        180 
PPARGPALPG AGPAPLTPDP CDYEARFSRL HGRAPGFLHC ASFGDPHVRS FHNQFHTCRV 
       190        200        210        220        230        240 
QGAWPLLDND FLFVQATSSP VSSGANATTI RKITIIFKNM QECIDQKVYQ AEVDNLPAAF 
       250        260        270        280        290        300 
EDGSINGGDR PGGSSLSIQT ANLGSHVEIR AAYIGTTIII RQTAGQLSFS IRVAEDVARA 
       310        320        330        340        350        360 
FSAEQDLQLC VGGCPPSQRL SRSERNRRGA IAIDTARRLC KEGLPVEDAY FQSCVFDVSV 
       370        380        390        400        410        420 
SGDPNFTVAA QTALDDARIF LTDLENLHLF PSDAGPPLSP AICLVPLLSA LFVLWLCFSK 
   



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q7TQ32-33-unknown QCKILR... 33 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q7TQ32-220-unknown MQECID... 220 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87429

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)