TopFIND 4.0

Q7TSC3: Serine/threonine-protein kinase Nek5

General Information

Protein names
- Serine/threonine-protein kinase Nek5
- 2.7.11.1
- Never in mitosis A-related kinase 5
- NimA-related protein kinase 5
Gene names Nek5
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q7TSC3

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDNFHLIKII GEGTFGKVYL AKDKSESSHC VIKEISLTKE KEASKNEVIL LARMEHPNIV 
        70         80         90        100        110        120 
TFFSSFQENG RLFIVMEYCD GGDLMQRIQR QRGVMFSEDQ ILCWFVQISL GLKHIHDRKI 
       130        140        150        160        170        180 
LHRDIKSQNI FLSKNGMVAK LGDFGTARTL NDSMELAQTC AGTPYYLSPE ICQNRPYNNK 
       190        200        210        220        230        240 
TDIWSLGCVL YELCTLKHPF ESNNFHHLVL KICQGRVAPI SPHFSRDLQS LIPQLFRVSP 
       250        260        270        280        290        300 
QDRPSVTSLL KRPFLETLIA RSLYPEVCSR RIQSHAHMEN MAIGPTACWR VSPWSAAYLQ 
       310        320        330        340        350        360 
RKFEAQQYKL KVERQLGLRP SSVEPHPNEG EKLQSHWEET KFQELQYRKN KMKDQEYWKQ 
       370        380        390        400        410        420 
LEEIRQQYHN DMKEIKKKMG RELKRVVKFE ISLDKCISEE DTVQENEAVD KLNATLSFED 
       430        440        450        460        470        480 
GTKFQEHRCK EEHEDYTDRA FEELCGPEAE GFFQDVIAAE NRRQWDAGAP HTLLRIMAMA 
       490        500        510        520        530        540 
DVTSTCPTMP DDGQVIVMEG SVENGKQWWL DVPGTPCALA AECACSGSLS ASKGETVMIK 
       550        560        570        580        590        600 
PQLPKEDQEK VEIATGIMVD DEQLEPGSDE DDIKFEESED ELRSEIIESL EKLAASTEEA 
       610        620    
EQAPSSSKNA EEPGEKEKTN LPVKKLQ

Isoforms

- Isoform 2 of Serine/threonine-protein kinase Nek5 - Isoform 3 of Serine/threonine-protein kinase Nek5

Sequence View

        10         20         30         40         50         60 
MDNFHLIKII GEGTFGKVYL AKDKSESSHC VIKEISLTKE KEASKNEVIL LARMEHPNIV 
        70         80         90        100        110        120 
TFFSSFQENG RLFIVMEYCD GGDLMQRIQR QRGVMFSEDQ ILCWFVQISL GLKHIHDRKI 
       130        140        150        160        170        180 
LHRDIKSQNI FLSKNGMVAK LGDFGTARTL NDSMELAQTC AGTPYYLSPE ICQNRPYNNK 
       190        200        210        220        230        240 
TDIWSLGCVL YELCTLKHPF ESNNFHHLVL KICQGRVAPI SPHFSRDLQS LIPQLFRVSP 
       250        260        270        280        290        300 
QDRPSVTSLL KRPFLETLIA RSLYPEVCSR RIQSHAHMEN MAIGPTACWR VSPWSAAYLQ 
       310        320        330        340        350        360 
RKFEAQQYKL KVERQLGLRP SSVEPHPNEG EKLQSHWEET KFQELQYRKN KMKDQEYWKQ 
       370        380        390        400        410        420 
LEEIRQQYHN DMKEIKKKMG RELKRVVKFE ISLDKCISEE DTVQENEAVD KLNATLSFED 
       430        440        450        460        470        480 
GTKFQEHRCK EEHEDYTDRA FEELCGPEAE GFFQDVIAAE NRRQWDAGAP HTLLRIMAMA 
       490        500        510        520        530        540 
DVTSTCPTMP DDGQVIVMEG SVENGKQWWL DVPGTPCALA AECACSGSLS ASKGETVMIK 
       550        560        570        580        590        600 
PQLPKEDQEK VEIATGIMVD DEQLEPGSDE DDIKFEESED ELRSEIIESL EKLAASTEEA 
       610        620    
EQAPSSSKNA EEPGEKEKTN LPVKKLQ         10         20         30         40         50         60 
MDNFHLIKII GEGTFGKVYL AKDKSESSHC VIKEISLTKE KEASKNEVIL LARMEHPNIV 
        70         80         90        100        110        120 
TFFSSFQENG RLFIVMEYCD GGDLMQRIQR QRGVMFSEDQ ILCWFVQISL GLKHIHDRKI 
       130        140        150        160        170        180 
LHRDIKSQNI FLSKNGMVAK LGDFGTARTL NDSMELAQTC AGTPYYLSPE ICQNRPYNNK 
       190        200        210        220        230        240 
TDIWSLGCVL YELCTLKHPF ESNNFHHLVL KICQGRVAPI SPHFSRDLQS LIPQLFRVSP 
       250        260        270        280        290        300 
QDRPSVTSLL KRPFLETLIA RSLYPEVCSR RIQSHAHMEN MAIGPTACWR VSPWSAAYLQ 
       310        320        330        340        350        360 
RKFEAQQYKL KVERQLGLRP SSVEPHPNEG EKLQSHWEET KFQELQYRKN KMKDQEYWKQ 
       370        380        390        400        410        420 
LEEIRQQYHN DMKEIKKKMG RELKRVVKFE ISLDKCISEE DTVQENEAVD KLNATLSFED 
       430        440        450        460        470        480 
GTKFQEHRCK EEHEDYTDRA FEELCGPEAE GFFQDVIAAE NRRQWDAGAP HTLLRIMAMA 
       490        500        510        520        530        540 
DVTSTCPTMP DDGQVIVMEG SVENGKQWWL DVPGTPCALA AECACSGSLS ASKGETVMIK 
       550        560        570        580        590        600 
PQLPKEDQEK VEIATGIMVD DEQLEPGSDE DDIKFEESED ELRSEIIESL EKLAASTEEA 
       610        620    
EQAPSSSKNA EEPGEKEKTN LPVKKLQ



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q7TSC3-1-unknown MDNFHL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q7TSC3-1-unknown MDNFHL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82594
    Q7TSC3-1-unknown MDNFHL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82595

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VKKLQ 627 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)