TopFIND 4.0

Q7TSU1: Brefeldin A-inhibited guanine nucleotide-exchange protein 2

General Information

Protein names
- Brefeldin A-inhibited guanine nucleotide-exchange protein 2
- Brefeldin A-inhibited GEP 2
- ADP-ribosylation factor guanine nucleotide-exchange factor 2
Gene names Arfgef2
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q7TSU1

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQESQTKSMF VSRALEKILA DKEVKRPQHS QLRRACQVAL DEIKAELEKQ RLGAAAPPKA 
        70         80         90        100        110        120 
NFIEADKYFL PFELACQSKS PRVVSTSLDC LQKLIAYGHI TGNAPDSGAP GKRLIDRIVE 
       130        140        150        160        170        180 
TVCNCFQGPQ TDEGVQLQII KALLTAVTSP HIEIHEGTIL QTVRTCYNIY LASKNLINQT 
       190        200        210        220        230        240 
TAKATLTQML NVIFTRMENQ VLQEARELEK PIQSKPQSPV IQATAGSPKF SRLKQSQAQS 
       250        260        270        280        290        300 
KPTTPEKTEL PNGDHARSSL GKVNSENGEA HRERGSSISG RAEPSGGSDN GAQEVVKDIL 
       310        320        330        340        350        360 
EDVVTSAVKE AAEKQGLPEP DQAPGVPECQ ECTVPPAVDE NSQTNGIADD RQSLSSADNL 
       370        380        390        400        410        420 
EPDAQGHPVA ARFSHILQKD AFLVFRSLCK LSMKPLGEGP PDPKSHELRS KVVSLQLLLS 
       430        440        450        460        470        480 
VLQNAGPVFR SHEMFVTAIK QYLCVALSKN GVSSVPDVFE LSLAIFLTLL SNFKMHLKMQ 
       490        500        510        520        530        540 
IEVFFKEIFL NILETSTSSF EHRWMVIQTL TRICADAQCV VDIYVNYDCD LNAANIFERL 
       550        560        570        580        590        600 
VNDLSKIAQG RSGHELGMTP LQELSLRKKG LECLVSILKC MVEWSKDLYV NPNHQATLGQ 
       610        620        630        640        650        660 
ERLPDQEMGD GKGLDMARRC SVTSVESTVS SGTQTAIPDD PEQFEVIKQQ KEIIEHGIEL 
       670        680        690        700        710        720 
FNKKPKRGIQ FLQEQGMLGA AVEDIAQFLH QEERLDSTQV GEFLGDSTRF NKEVMYAYVD 
       730        740        750        760        770        780 
QLDFCEKEFV SALRTFLEGF RLPGEAQKID RLMEKFAARY IECNQGQTLF ASADTAYVLA 
       790        800        810        820        830        840 
YSIIMLTTDL HSPQVKNKMT KEQYIKMNRG INDSKDLPEE YLSSIYEEIE GKKIAMKETK 
       850        860        870        880        890        900 
EHTMATKSTK QNVASEKQRR LLYNVEMEQM AKTAKALMEA VSHAKAPFTS ATHLDHVRPM 
       910        920        930        940        950        960 
FKLVWTPLLA AYSIGLQNCD DTEVASLCLE GIRCAVRIAC IFGMQLERDA YVQALARFSL 
       970        980        990       1000       1010       1020 
LTASSSITEM KQKNIDTIKT LITVAHTDGN YLGNSWHEIL KCISQLELAQ LIGTGVKTRY 
      1030       1040       1050       1060       1070       1080 
LSGSGREREG SLKGHSLAGE EFMGLGLGNL VSGGVDKRQM ASFQESVGET SSQSVVVAVD 
      1090       1100       1110       1120       1130       1140 
RIFTGSTRLD GNAIVDFVRW LCAVSMDELA SPHHPRMFSL QKIVEISYYN MNRIRLQWSR 
      1150       1160       1170       1180       1190       1200 
IWHVIGDHFN KVGCNPNEDV AIFAVDSLRQ LSMKFLEKGE LANFRFQKDF LRPFEHIMKK 
      1210       1220       1230       1240       1250       1260 
NRSPTIRDMV IRCIAQMVSS QAANIRSGWK NIFAVFHQAA SDHDGNIVEL AFQTTGHIVS 
      1270       1280       1290       1300       1310       1320 
TIFQHHFPAA IDSFQDAVKC LSEFACNAAF PDTSMEAIRL IRFCGKYVSE RPRVLQEYTS 
      1330       1340       1350       1360       1370       1380 
DDMNVAPGDR VWVRGWFPIL FELSCIINRC KLDVRTRGLT VMFEIMKSYG HTFAKHWWQD 
      1390       1400       1410       1420       1430       1440 
LFRIVFRIFD NMKLPEQQSE KSEWMTTTCN HALYAICDVF TQFYEALHEV LLSDVFAQLQ 
      1450       1460       1470       1480       1490       1500 
WCVKQDNEQL ARSGTNCLEN LVISNGEKFS PAVWDETCNC MLDIFRTTIP HVLLTWRPAG 
      1510       1520       1530       1540       1550       1560 
MEEEVSDRHL DVDLDRQSLS SIDRNASERG QSQLSNPTDD SWKGAPYANQ KLLASLLIKC 
      1570       1580       1590       1600       1610       1620 
VVQLELIQTI DNIVFYPATS KKEDAEHMVA AQQDTLDADI HIETENQGMY KFMSSQHLFK 
      1630       1640       1650       1660       1670       1680 
LLDCLQESHS FSKAFNSNYE QRTVLWRAGF KGKSKPNLLK QETSSLACCL RILFRMYVDE 
      1690       1700       1710       1720       1730       1740 
NRRDSWGEIQ QRLLTVCSEA LAYFITVNSE SHREAWTSLL LLLLTKTLKI NDEKFKAHAS 
      1750       1760       1770       1780       1790    
VYYPYLCEMM QFDLIPELRA VLRKFFLRIG LVYKIWVPEE PSQVPAASTA W

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q7TSU1-1-Acetylation MQESQT... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ASTAW 1791 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)