Q7Z569: BRCA1-associated protein

General Information

Protein names	- BRCA1-associated protein - 2.3.2.27 {ECO:0000269\|PubMed:14724641} - BRAP2 - Impedes mitogenic signal propagation - IMP - RING finger protein 52 - RING-type E3 ubiquitin transferase BRAP2 {ECO:0000305} - Renal carcinoma antigen NY-REN-63
Gene names	BRAP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z569

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSVSLVVIRL ELAEHSPVPA GFGFSAAAGE MSDEEIKKTT LASAVACLEG KSPGEKVAII
        70         80         90        100        110        120
HQHLGRREMT DVIIETMKSN PDELKTTVEE RKSSEASPTA QRSKDHSKEC INAAPDSPSK
       130        140        150        160        170        180
QLPDQISFFS GNPSVEIVHG IMHLYKTNKM TSLKEDVRRS AMLCILTVPA AMTSHDLMKF
       190        200        210        220        230        240
VAPFNEVIEQ MKIIRDSTPN QYMVLIKFRA QADADSFYMT CNGRQFNSIE DDVCQLVYVE
       250        260        270        280        290        300
RAEVLKSEDG ASLPVMDLTE LPKCTVCLER MDESVNGILT TLCNHSFHSQ CLQRWDDTTC
       310        320        330        340        350        360
PVCRYCQTPE PVEENKCFEC GVQENLWICL ICGHIGCGRY VSRHAYKHFE ETQHTYAMQL
       370        380        390        400        410        420
TNHRVWDYAG DNYVHRLVAS KTDGKIVQYE CEGDTCQEEK IDALQLEYSY LLTSQLESQR
       430        440        450        460        470        480
IYWENKIVRI EKDTAEEINN MKTKFKETIE KCDNLEHKLN DLLKEKQSVE RKCTQLNTKV
       490        500        510        520        530        540
AKLTNELKEE QEMNKCLRAN QVLLQNKLKE EERVLKETCD QKDLQITEIQ EQLRDVMFYL
       550        560        570        580        590
ETQQKINHLP AETRQEIQEG QINIAMASAS SPASSGGSGK LPSRKGRSKR GK

Isoforms

- Isoform 2 of BRCA1-associated protein

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z569-1-unknown	MSVSLV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z569-2-acetylation	SVSLVV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q7Z569-2-acetylation	SVSLVV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q7Z569-31-unknown	MSDEEI...	31		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000330813
Q7Z569-142-unknown	MHLYKT...	142		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000441659

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...SKRGK	592	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)