TopFIND 4.0

Q7Z5M8: Protein ABHD12B {ECO:0000305}

General Information

Protein names
- Protein ABHD12B {ECO:0000305}
- 3.-.-.-
- Abhydrolase domain-containing protein 12B {ECO:0000312|HGNC:HGNC:19837}
- Alpha/beta hydrolase domain-containing protein 12B {ECO:0000305}
Gene names ABHD12B
Organism Homo sapiens
Protease Family
Protease ID S09.061
Chromosome location
UniProt ID Q7Z5M8

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDAQDCQAAA SPEPPGPPAR SCVAAWWDMV DRNLRYFPHS CSMLGRKIAA LYDSFTSKSL 
        70         80         90        100        110        120 
KEHVFLPLID MLIYFNFFKA PFLVDLKKPE LKIPHTVNFY LRVEPGVMLG IWHTVPSCRG 
       130        140        150        160        170        180 
EDAKGKDCCW YEAALRDGNP IIVYLHGSAE HRAASHRLKL VKVLSDGGFH VLSVDYRGFG 
       190        200        210        220        230        240 
DSTGKPTEEG LTTDAICVYE WTKARSGITP VCLWGHSLGT GVATNAAKVL EEKGCPVDAI 
       250        260        270        280        290        300 
VLEAPFTNMW VASINYPLLK IYRNIPGFLR TLMDALRKDK IIFPNDENVK FLSSPLLILH 
       310        320        330        340        350        360 
GEDDRTVPLE YGKKLYEIAR NAYRNKERVK MVIFPPGFQH NLLCKSPTLL ITVRDFLSKQ 
   
WS

Isoforms

- Isoform 2 of Abhydrolase domain-containing protein 12B - Isoform 4 of Abhydrolase domain-containing protein 12B - Isoform 5 of Abhydrolase domain-containing protein 12B - Isoform 2 of Protein ABHD12B - Isoform 4 of Protein ABHD12B - Isoform 5 of Protein ABHD12B

Sequence View

        10         20         30         40         50         60 
MDAQDCQAAA SPEPPGPPAR SCVAAWWDMV DRNLRYFPHS CSMLGRKIAA LYDSFTSKSL 
        70         80         90        100        110        120 
KEHVFLPLID MLIYFNFFKA PFLVDLKKPE LKIPHTVNFY LRVEPGVMLG IWHTVPSCRG 
       130        140        150        160        170        180 
EDAKGKDCCW YEAALRDGNP IIVYLHGSAE HRAASHRLKL VKVLSDGGFH VLSVDYRGFG 
       190        200        210        220        230        240 
DSTGKPTEEG LTTDAICVYE WTKARSGITP VCLWGHSLGT GVATNAAKVL EEKGCPVDAI 
       250        260        270        280        290        300 
VLEAPFTNMW VASINYPLLK IYRNIPGFLR TLMDALRKDK IIFPNDENVK FLSSPLLILH 
       310        320        330        340        350        360 
GEDDRTVPLE YGKKLYEIAR NAYRNKERVK MVIFPPGFQH NLLCKSPTLL ITVRDFLSKQ 
   
WS         10         20         30         40         50         60 
MDAQDCQAAA SPEPPGPPAR SCVAAWWDMV DRNLRYFPHS CSMLGRKIAA LYDSFTSKSL 
        70         80         90        100        110        120 
KEHVFLPLID MLIYFNFFKA PFLVDLKKPE LKIPHTVNFY LRVEPGVMLG IWHTVPSCRG 
       130        140        150        160        170        180 
EDAKGKDCCW YEAALRDGNP IIVYLHGSAE HRAASHRLKL VKVLSDGGFH VLSVDYRGFG 
       190        200        210        220        230        240 
DSTGKPTEEG LTTDAICVYE WTKARSGITP VCLWGHSLGT GVATNAAKVL EEKGCPVDAI 
       250        260        270        280        290        300 
VLEAPFTNMW VASINYPLLK IYRNIPGFLR TLMDALRKDK IIFPNDENVK FLSSPLLILH 
       310        320        330        340        350        360 
GEDDRTVPLE YGKKLYEIAR NAYRNKERVK MVIFPPGFQH NLLCKSPTLL ITVRDFLSKQ 
   
WS         10         20         30         40         50         60 
MDAQDCQAAA SPEPPGPPAR SCVAAWWDMV DRNLRYFPHS CSMLGRKIAA LYDSFTSKSL 
        70         80         90        100        110        120 
KEHVFLPLID MLIYFNFFKA PFLVDLKKPE LKIPHTVNFY LRVEPGVMLG IWHTVPSCRG 
       130        140        150        160        170        180 
EDAKGKDCCW YEAALRDGNP IIVYLHGSAE HRAASHRLKL VKVLSDGGFH VLSVDYRGFG 
       190        200        210        220        230        240 
DSTGKPTEEG LTTDAICVYE WTKARSGITP VCLWGHSLGT GVATNAAKVL EEKGCPVDAI 
       250        260        270        280        290        300 
VLEAPFTNMW VASINYPLLK IYRNIPGFLR TLMDALRKDK IIFPNDENVK FLSSPLLILH 
       310        320        330        340        350        360 
GEDDRTVPLE YGKKLYEIAR NAYRNKERVK MVIFPPGFQH NLLCKSPTLL ITVRDFLSKQ 
   
WS         10         20         30         40         50         60 
MDAQDCQAAA SPEPPGPPAR SCVAAWWDMV DRNLRYFPHS CSMLGRKIAA LYDSFTSKSL 
        70         80         90        100        110        120 
KEHVFLPLID MLIYFNFFKA PFLVDLKKPE LKIPHTVNFY LRVEPGVMLG IWHTVPSCRG 
       130        140        150        160        170        180 
EDAKGKDCCW YEAALRDGNP IIVYLHGSAE HRAASHRLKL VKVLSDGGFH VLSVDYRGFG 
       190        200        210        220        230        240 
DSTGKPTEEG LTTDAICVYE WTKARSGITP VCLWGHSLGT GVATNAAKVL EEKGCPVDAI 
       250        260        270        280        290        300 
VLEAPFTNMW VASINYPLLK IYRNIPGFLR TLMDALRKDK IIFPNDENVK FLSSPLLILH 
       310        320        330        340        350        360 
GEDDRTVPLE YGKKLYEIAR NAYRNKERVK MVIFPPGFQH NLLCKSPTLL ITVRDFLSKQ 
   
WS         10         20         30         40         50         60 
MDAQDCQAAA SPEPPGPPAR SCVAAWWDMV DRNLRYFPHS CSMLGRKIAA LYDSFTSKSL 
        70         80         90        100        110        120 
KEHVFLPLID MLIYFNFFKA PFLVDLKKPE LKIPHTVNFY LRVEPGVMLG IWHTVPSCRG 
       130        140        150        160        170        180 
EDAKGKDCCW YEAALRDGNP IIVYLHGSAE HRAASHRLKL VKVLSDGGFH VLSVDYRGFG 
       190        200        210        220        230        240 
DSTGKPTEEG LTTDAICVYE WTKARSGITP VCLWGHSLGT GVATNAAKVL EEKGCPVDAI 
       250        260        270        280        290        300 
VLEAPFTNMW VASINYPLLK IYRNIPGFLR TLMDALRKDK IIFPNDENVK FLSSPLLILH 
       310        320        330        340        350        360 
GEDDRTVPLE YGKKLYEIAR NAYRNKERVK MVIFPPGFQH NLLCKSPTLL ITVRDFLSKQ 
   
WS         10         20         30         40         50         60 
MDAQDCQAAA SPEPPGPPAR SCVAAWWDMV DRNLRYFPHS CSMLGRKIAA LYDSFTSKSL 
        70         80         90        100        110        120 
KEHVFLPLID MLIYFNFFKA PFLVDLKKPE LKIPHTVNFY LRVEPGVMLG IWHTVPSCRG 
       130        140        150        160        170        180 
EDAKGKDCCW YEAALRDGNP IIVYLHGSAE HRAASHRLKL VKVLSDGGFH VLSVDYRGFG 
       190        200        210        220        230        240 
DSTGKPTEEG LTTDAICVYE WTKARSGITP VCLWGHSLGT GVATNAAKVL EEKGCPVDAI 
       250        260        270        280        290        300 
VLEAPFTNMW VASINYPLLK IYRNIPGFLR TLMDALRKDK IIFPNDENVK FLSSPLLILH 
       310        320        330        340        350        360 
GEDDRTVPLE YGKKLYEIAR NAYRNKERVK MVIFPPGFQH NLLCKSPTLL ITVRDFLSKQ 
   
WS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SKQWS 362 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SKQWS 362 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61525

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)