Q7Z5N4: Protein sidekick-1 {ECO:0000303|PubMed:15213259}
| Protein names | - Protein sidekick-1 {ECO:0000303|PubMed:15213259} |
|---|---|
| Gene names | SDK1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q7Z5N4 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MARGARPSAA GGGGGGAEPP ERAGPGRPRG SPPGRARPSL APRPGPEPSR PRAAPETSGG
70 80 90 100 110 120
DTAGAGRCGG RRAAKLGPGR RGWWALLALQ LHLLRALAQD DVAPYFKTEP GLPQIHLEGN
130 140 150 160 170 180
RLVLTCLAEG SWPLEFKWMR DDSELTTYSS EYKYIIPSLQ KLDAGFYRCV VRNRMGALLQ
190 200 210 220 230 240
RKSEVQVAYM GSFMDTDQRK TVSQGRAAIL NLLPITSYPR PQVTWFREGH KIIPSNRIAI
250 260 270 280 290 300
TLENQLVILA TTTSDAGAYY VQAVNEKNGE NKTSPFIHLS IARDVGTPET MAPTIVVPPG
310 320 330 340 350 360
NRSVVAGSSE TTLECIASAR PVEDLSVTWK RNGVRITSGL HSFGRRLTIS NPTSADTGPY
370 380 390 400 410 420
VCEAALPGSA FEPARATAFL FIIEPPYFTA EPESRISAEV EETVDIGCQA MGVPLPTLQW
430 440 450 460 470 480
YKDAISISRL QNPRYKVLAS GGLRIQKLRP EDSGIFQCFA SNEGGEIQTH TYLDVTNIAP
490 500 510 520 530 540
VFTQRPVDTT VTDGMTAILR CEVSGAPKPA ITWKRENHIL ASGSVRIPRF MLLESGGLQI
550 560 570 580 590 600
APVFIQDAGN YTCYAANTEG SLNASATLTV WNRTSIVHPP EDHVVIKGTT ATLHCGATHD
610 620 630 640 650 660
PRVSLRYVWK KDNVALTPSS TSRIVVEKDG SLLISQTWSG DIGDYSCEIV SEGGNDSRMA
670 680 690 700 710 720
RLEVIELPHS PQNLLVSPNS SHSHAVVLSW VRPFDGNSPI LYYIVELSEN NSPWKVHLSN
730 740 750 760 770 780
VGPEMTGVTV SGLTPARTYQ FRVCAVNEVG RGQYSAETSR LMLPEEPPSA PPKNIVASGR
790 800 810 820 830 840
TNQSIMVQWQ PPPETEHNGV LRGYILRYRL AGLPGEYQQR NITSPEVNYC LVTDLIIWTQ
850 860 870 880 890 900
YEIQVAAYNG AGLGVFSRAV TEYTLQGVPT APPQNVQTEA VNSTTIQFLW NPPPQQFING
910 920 930 940 950 960
INQGYKLLAW PADAPEAVTV VTIAPDFHGV HHGHITNLKK FTAYFTSVLC FTTPGDGPPS
970 980 990 1000 1010 1020
TPQLVWTQED KPGAVGHLSF TEILDTSLKV SWQEPLEKNG IITGYQISWE VYGRNDSRLT
1030 1040 1050 1060 1070 1080
HTLNSTTHEY KIQGLSSLTT YTIDVAAVTA VGTGLVTSST ISSGVPPDLP GAPSNLVISN
1090 1100 1110 1120 1130 1140
ISPRSATLQF RPGYDGKTSI SRWIVEGQVG AIGDEEEWVT LYEEENEPDA QMLEIPNLTP
1150 1160 1170 1180 1190 1200
YTHYRFRMKQ VNIVGPSPYS PSSRVIQTLQ APPDVAPTSV TVRTASETSL RLRWVPLPDS
1210 1220 1230 1240 1250 1260
QYNGNPESVG YRIKYWRSDL QSSAVAQVVS DRLEREFTIE ELEEWMEYEL QMQAFNAVGA
1270 1280 1290 1300 1310 1320
GPWSEVVRGR TRESVPSAAP ENVSAEAVSS TQILLTWTSV PEQDQNGLIL GYKILFRAKD
1330 1340 1350 1360 1370 1380
LDPEPRSHIV RGNHTQSALL AGLRKFVLYE LQVLAFTRIG NGVPSTPLIL ERTKDDAPGP
1390 1400 1410 1420 1430 1440
PVRLVFPEVR LTSVRIVWQP PEEPNGIILG YQIAYRLASS SPHTFTTVEV GATVRQFTAT
1450 1460 1470 1480 1490 1500
DLAPESAYIF RLSAKTRQGW GEPLEATVIT TEKRERPAPP RELLVPQAEV TARSLRLQWV
1510 1520 1530 1540 1550 1560
PGSDGASPIR YFTMQVRELP RGEWQTYSSS ISHEATACVV DRLRPFTSYK LRLKATNDIG
1570 1580 1590 1600 1610 1620
DSDFSSETEA VTTLQDVPGE PPGSVSATPH TTSSVLIQWQ PPRDESLNGL LQGYRIYYRE
1630 1640 1650 1660 1670 1680
LEYEAGSGTE AKTLKNPIAL HAELTAQSSF KTVNSSSTST MCELTHLKKY RRYEVIMTAY
1690 1700 1710 1720 1730 1740
NIIGESPASA PVEVFVGEAA PAMAPQNVQV TPLTASQLEV TWDPPPPESQ NGNIQGYKIY
1750 1760 1770 1780 1790 1800
YWEADSQNET EKMKVLFLPE PVVRLKNLTS HTKYLVSISA FNAAGDGPKS DPQQGRTHQA
1810 1820 1830 1840 1850 1860
APGAPSFLAF SEITSTTLNV SWGEPAAANG ILQGYRVVYE PLAPVQGVSK VVTVEVRGNW
1870 1880 1890 1900 1910 1920
QRWLKVRDLT KGVTYFFRVQ ARTITYGPEL QANITAGPAE GSPGSPRDVL VTKSASELTL
1930 1940 1950 1960 1970 1980
QWTEGHSGDT PTTGYVIEAR PSDEGLWDMF VKDIPRSATS YTLSLDKLRQ GVTYEFRVVA
1990 2000 2010 2020 2030 2040
VNEAGYGEPS NPSTAVSAQV EAPFYEEWWF LLVMALSSLI VILLVVFALV LHGQNKKYKN
2050 2060 2070 2080 2090 2100
CSTGKGISTM EESVTLDNGG FAALELSSRH LNVKSTFSKK NGTRSPPRPS PGGLHYSDED
2110 2120 2130 2140 2150 2160
ICNKYNGAVL TESVSLKEKS ADASESEATD SDYEDALPKH SFVNHYMSDP TYYNSWKRRA
2170 2180 2190 2200 2210
QGRAPAPHRY EAVAGSEAGA QLHPVITTQS AGGVYTPAGP GARTPLTGFS SFV
Isoforms
- Isoform 2 of Protein sidekick-1 - Isoform 3 of Protein sidekick-1Sequence View
10 20 30 40 50 60
MARGARPSAA GGGGGGAEPP ERAGPGRPRG SPPGRARPSL APRPGPEPSR PRAAPETSGG
70 80 90 100 110 120
DTAGAGRCGG RRAAKLGPGR RGWWALLALQ LHLLRALAQD DVAPYFKTEP GLPQIHLEGN
130 140 150 160 170 180
RLVLTCLAEG SWPLEFKWMR DDSELTTYSS EYKYIIPSLQ KLDAGFYRCV VRNRMGALLQ
190 200 210 220 230 240
RKSEVQVAYM GSFMDTDQRK TVSQGRAAIL NLLPITSYPR PQVTWFREGH KIIPSNRIAI
250 260 270 280 290 300
TLENQLVILA TTTSDAGAYY VQAVNEKNGE NKTSPFIHLS IARDVGTPET MAPTIVVPPG
310 320 330 340 350 360
NRSVVAGSSE TTLECIASAR PVEDLSVTWK RNGVRITSGL HSFGRRLTIS NPTSADTGPY
370 380 390 400 410 420
VCEAALPGSA FEPARATAFL FIIEPPYFTA EPESRISAEV EETVDIGCQA MGVPLPTLQW
430 440 450 460 470 480
YKDAISISRL QNPRYKVLAS GGLRIQKLRP EDSGIFQCFA SNEGGEIQTH TYLDVTNIAP
490 500 510 520 530 540
VFTQRPVDTT VTDGMTAILR CEVSGAPKPA ITWKRENHIL ASGSVRIPRF MLLESGGLQI
550 560 570 580 590 600
APVFIQDAGN YTCYAANTEG SLNASATLTV WNRTSIVHPP EDHVVIKGTT ATLHCGATHD
610 620 630 640 650 660
PRVSLRYVWK KDNVALTPSS TSRIVVEKDG SLLISQTWSG DIGDYSCEIV SEGGNDSRMA
670 680 690 700 710 720
RLEVIELPHS PQNLLVSPNS SHSHAVVLSW VRPFDGNSPI LYYIVELSEN NSPWKVHLSN
730 740 750 760 770 780
VGPEMTGVTV SGLTPARTYQ FRVCAVNEVG RGQYSAETSR LMLPEEPPSA PPKNIVASGR
790 800 810 820 830 840
TNQSIMVQWQ PPPETEHNGV LRGYILRYRL AGLPGEYQQR NITSPEVNYC LVTDLIIWTQ
850 860 870 880 890 900
YEIQVAAYNG AGLGVFSRAV TEYTLQGVPT APPQNVQTEA VNSTTIQFLW NPPPQQFING
910 920 930 940 950 960
INQGYKLLAW PADAPEAVTV VTIAPDFHGV HHGHITNLKK FTAYFTSVLC FTTPGDGPPS
970 980 990 1000 1010 1020
TPQLVWTQED KPGAVGHLSF TEILDTSLKV SWQEPLEKNG IITGYQISWE VYGRNDSRLT
1030 1040 1050 1060 1070 1080
HTLNSTTHEY KIQGLSSLTT YTIDVAAVTA VGTGLVTSST ISSGVPPDLP GAPSNLVISN
1090 1100 1110 1120 1130 1140
ISPRSATLQF RPGYDGKTSI SRWIVEGQVG AIGDEEEWVT LYEEENEPDA QMLEIPNLTP
1150 1160 1170 1180 1190 1200
YTHYRFRMKQ VNIVGPSPYS PSSRVIQTLQ APPDVAPTSV TVRTASETSL RLRWVPLPDS
1210 1220 1230 1240 1250 1260
QYNGNPESVG YRIKYWRSDL QSSAVAQVVS DRLEREFTIE ELEEWMEYEL QMQAFNAVGA
1270 1280 1290 1300 1310 1320
GPWSEVVRGR TRESVPSAAP ENVSAEAVSS TQILLTWTSV PEQDQNGLIL GYKILFRAKD
1330 1340 1350 1360 1370 1380
LDPEPRSHIV RGNHTQSALL AGLRKFVLYE LQVLAFTRIG NGVPSTPLIL ERTKDDAPGP
1390 1400 1410 1420 1430 1440
PVRLVFPEVR LTSVRIVWQP PEEPNGIILG YQIAYRLASS SPHTFTTVEV GATVRQFTAT
1450 1460 1470 1480 1490 1500
DLAPESAYIF RLSAKTRQGW GEPLEATVIT TEKRERPAPP RELLVPQAEV TARSLRLQWV
1510 1520 1530 1540 1550 1560
PGSDGASPIR YFTMQVRELP RGEWQTYSSS ISHEATACVV DRLRPFTSYK LRLKATNDIG
1570 1580 1590 1600 1610 1620
DSDFSSETEA VTTLQDVPGE PPGSVSATPH TTSSVLIQWQ PPRDESLNGL LQGYRIYYRE
1630 1640 1650 1660 1670 1680
LEYEAGSGTE AKTLKNPIAL HAELTAQSSF KTVNSSSTST MCELTHLKKY RRYEVIMTAY
1690 1700 1710 1720 1730 1740
NIIGESPASA PVEVFVGEAA PAMAPQNVQV TPLTASQLEV TWDPPPPESQ NGNIQGYKIY
1750 1760 1770 1780 1790 1800
YWEADSQNET EKMKVLFLPE PVVRLKNLTS HTKYLVSISA FNAAGDGPKS DPQQGRTHQA
1810 1820 1830 1840 1850 1860
APGAPSFLAF SEITSTTLNV SWGEPAAANG ILQGYRVVYE PLAPVQGVSK VVTVEVRGNW
1870 1880 1890 1900 1910 1920
QRWLKVRDLT KGVTYFFRVQ ARTITYGPEL QANITAGPAE GSPGSPRDVL VTKSASELTL
1930 1940 1950 1960 1970 1980
QWTEGHSGDT PTTGYVIEAR PSDEGLWDMF VKDIPRSATS YTLSLDKLRQ GVTYEFRVVA
1990 2000 2010 2020 2030 2040
VNEAGYGEPS NPSTAVSAQV EAPFYEEWWF LLVMALSSLI VILLVVFALV LHGQNKKYKN
2050 2060 2070 2080 2090 2100
CSTGKGISTM EESVTLDNGG FAALELSSRH LNVKSTFSKK NGTRSPPRPS PGGLHYSDED
2110 2120 2130 2140 2150 2160
ICNKYNGAVL TESVSLKEKS ADASESEATD SDYEDALPKH SFVNHYMSDP TYYNSWKRRA
2170 2180 2190 2200 2210
QGRAPAPHRY EAVAGSEAGA QLHPVITTQS AGGVYTPAGP GARTPLTGFS SFV
10 20 30 40 50 60
MARGARPSAA GGGGGGAEPP ERAGPGRPRG SPPGRARPSL APRPGPEPSR PRAAPETSGG
70 80 90 100 110 120
DTAGAGRCGG RRAAKLGPGR RGWWALLALQ LHLLRALAQD DVAPYFKTEP GLPQIHLEGN
130 140 150 160 170 180
RLVLTCLAEG SWPLEFKWMR DDSELTTYSS EYKYIIPSLQ KLDAGFYRCV VRNRMGALLQ
190 200 210 220 230 240
RKSEVQVAYM GSFMDTDQRK TVSQGRAAIL NLLPITSYPR PQVTWFREGH KIIPSNRIAI
250 260 270 280 290 300
TLENQLVILA TTTSDAGAYY VQAVNEKNGE NKTSPFIHLS IARDVGTPET MAPTIVVPPG
310 320 330 340 350 360
NRSVVAGSSE TTLECIASAR PVEDLSVTWK RNGVRITSGL HSFGRRLTIS NPTSADTGPY
370 380 390 400 410 420
VCEAALPGSA FEPARATAFL FIIEPPYFTA EPESRISAEV EETVDIGCQA MGVPLPTLQW
430 440 450 460 470 480
YKDAISISRL QNPRYKVLAS GGLRIQKLRP EDSGIFQCFA SNEGGEIQTH TYLDVTNIAP
490 500 510 520 530 540
VFTQRPVDTT VTDGMTAILR CEVSGAPKPA ITWKRENHIL ASGSVRIPRF MLLESGGLQI
550 560 570 580 590 600
APVFIQDAGN YTCYAANTEG SLNASATLTV WNRTSIVHPP EDHVVIKGTT ATLHCGATHD
610 620 630 640 650 660
PRVSLRYVWK KDNVALTPSS TSRIVVEKDG SLLISQTWSG DIGDYSCEIV SEGGNDSRMA
670 680 690 700 710 720
RLEVIELPHS PQNLLVSPNS SHSHAVVLSW VRPFDGNSPI LYYIVELSEN NSPWKVHLSN
730 740 750 760 770 780
VGPEMTGVTV SGLTPARTYQ FRVCAVNEVG RGQYSAETSR LMLPEEPPSA PPKNIVASGR
790 800 810 820 830 840
TNQSIMVQWQ PPPETEHNGV LRGYILRYRL AGLPGEYQQR NITSPEVNYC LVTDLIIWTQ
850 860 870 880 890 900
YEIQVAAYNG AGLGVFSRAV TEYTLQGVPT APPQNVQTEA VNSTTIQFLW NPPPQQFING
910 920 930 940 950 960
INQGYKLLAW PADAPEAVTV VTIAPDFHGV HHGHITNLKK FTAYFTSVLC FTTPGDGPPS
970 980 990 1000 1010 1020
TPQLVWTQED KPGAVGHLSF TEILDTSLKV SWQEPLEKNG IITGYQISWE VYGRNDSRLT
1030 1040 1050 1060 1070 1080
HTLNSTTHEY KIQGLSSLTT YTIDVAAVTA VGTGLVTSST ISSGVPPDLP GAPSNLVISN
1090 1100 1110 1120 1130 1140
ISPRSATLQF RPGYDGKTSI SRWIVEGQVG AIGDEEEWVT LYEEENEPDA QMLEIPNLTP
1150 1160 1170 1180 1190 1200
YTHYRFRMKQ VNIVGPSPYS PSSRVIQTLQ APPDVAPTSV TVRTASETSL RLRWVPLPDS
1210 1220 1230 1240 1250 1260
QYNGNPESVG YRIKYWRSDL QSSAVAQVVS DRLEREFTIE ELEEWMEYEL QMQAFNAVGA
1270 1280 1290 1300 1310 1320
GPWSEVVRGR TRESVPSAAP ENVSAEAVSS TQILLTWTSV PEQDQNGLIL GYKILFRAKD
1330 1340 1350 1360 1370 1380
LDPEPRSHIV RGNHTQSALL AGLRKFVLYE LQVLAFTRIG NGVPSTPLIL ERTKDDAPGP
1390 1400 1410 1420 1430 1440
PVRLVFPEVR LTSVRIVWQP PEEPNGIILG YQIAYRLASS SPHTFTTVEV GATVRQFTAT
1450 1460 1470 1480 1490 1500
DLAPESAYIF RLSAKTRQGW GEPLEATVIT TEKRERPAPP RELLVPQAEV TARSLRLQWV
1510 1520 1530 1540 1550 1560
PGSDGASPIR YFTMQVRELP RGEWQTYSSS ISHEATACVV DRLRPFTSYK LRLKATNDIG
1570 1580 1590 1600 1610 1620
DSDFSSETEA VTTLQDVPGE PPGSVSATPH TTSSVLIQWQ PPRDESLNGL LQGYRIYYRE
1630 1640 1650 1660 1670 1680
LEYEAGSGTE AKTLKNPIAL HAELTAQSSF KTVNSSSTST MCELTHLKKY RRYEVIMTAY
1690 1700 1710 1720 1730 1740
NIIGESPASA PVEVFVGEAA PAMAPQNVQV TPLTASQLEV TWDPPPPESQ NGNIQGYKIY
1750 1760 1770 1780 1790 1800
YWEADSQNET EKMKVLFLPE PVVRLKNLTS HTKYLVSISA FNAAGDGPKS DPQQGRTHQA
1810 1820 1830 1840 1850 1860
APGAPSFLAF SEITSTTLNV SWGEPAAANG ILQGYRVVYE PLAPVQGVSK VVTVEVRGNW
1870 1880 1890 1900 1910 1920
QRWLKVRDLT KGVTYFFRVQ ARTITYGPEL QANITAGPAE GSPGSPRDVL VTKSASELTL
1930 1940 1950 1960 1970 1980
QWTEGHSGDT PTTGYVIEAR PSDEGLWDMF VKDIPRSATS YTLSLDKLRQ GVTYEFRVVA
1990 2000 2010 2020 2030 2040
VNEAGYGEPS NPSTAVSAQV EAPFYEEWWF LLVMALSSLI VILLVVFALV LHGQNKKYKN
2050 2060 2070 2080 2090 2100
CSTGKGISTM EESVTLDNGG FAALELSSRH LNVKSTFSKK NGTRSPPRPS PGGLHYSDED
2110 2120 2130 2140 2150 2160
ICNKYNGAVL TESVSLKEKS ADASESEATD SDYEDALPKH SFVNHYMSDP TYYNSWKRRA
2170 2180 2190 2200 2210
QGRAPAPHRY EAVAGSEAGA QLHPVITTQS AGGVYTPAGP GARTPLTGFS SFV
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q7Z5N4-0-unknown | VMARGA... | 0 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q7Z5N4-1-unknown | MARGAR... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q7Z5N4-1-unknown | MARGAR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt89161 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...FSSFV | 2213 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...FSSFV | 2213 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt84778 | |||
| ...FSSFV | 2213 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt84779 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|