Q7Z5R6: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein

General Information

Protein names	- Amyloid beta A4 precursor protein-binding family B member 1-interacting protein - APBB1-interacting protein 1 - Proline-rich EVH1 ligand 1 - PREL-1 - Proline-rich protein 73 - Rap1-GTP-interacting adapter molecule - RIAM - Retinoic acid-responsive proline-rich protein 1 - RARP-1
Gene names	APBB1IP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z5R6

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGESSEDIDQ MFSTLLGEMD LLTQSLGVDT LPPPDPNPPR AEFNYSVGFK DLNESLNALE
        70         80         90        100        110        120
DQDLDALMAD LVADISEAEQ RTIQAQKESL QNQHHSASLQ ASIFSGAASL GYGTNVAATG
       130        140        150        160        170        180
ISQYEDDLPP PPADPVLDLP LPPPPPEPLS QEEEEAQAKA DKIKLALEKL KEAKVKKLVV
       190        200        210        220        230        240
KVHMNDNSTK SLMVDERQLA RDVLDNLFEK THCDCNVDWC LYEIYPELQI ERFFEDHENV
       250        260        270        280        290        300
VEVLSDWTRD TENKILFLEK EEKYAVFKNP QNFYLDNRGK KESKETNEKM NAKNKESLLE
       310        320        330        340        350        360
ESFCGTSIIV PELEGALYLK EDGKKSWKRR YFLLRASGIY YVPKGKTKTS RDLACFIQFE
       370        380        390        400        410        420
NVNIYYGTQH KMKYKAPTDY CFVLKHPQIQ KESQYIKYLC CDDTRTLNQW VMGIRIAKYG
       430        440        450        460        470        480
KTLYDNYQRA VAKAGLASRW TNLGTVNAAA PAQPSTGPKT GTTQPNGQIP QATHSVSAVL
       490        500        510        520        530        540
QEAQRHAETS KDKKPALGNH HDPAVPRAPH APKSSLPPPP PVRRSSDTSG SPATPLKAKG
       550        560        570        580        590        600
TGGGGLPAPP DDFLPPPPPP PPLDDPELPP PPPDFMEPPP DFVPPPPPSY AGIAGSELPP
       610        620        630        640        650        660
PPPPPPAPAP APVPDSARPP PAVAKRPPVP PKRQENPGHP GGAGGGEQDF MSDLMKALQK

KRGNVS

Isoforms

- Isoform 2 of Amyloid beta A4 precursor protein-binding family B member 1-interacting protein

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z5R6-1-unknown	MGESSE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z5R6-445-	TVNAAA...	445		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q7Z5R6-448-	AAAPAQ...	448		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q7Z5R6-448-	AAAPAQ...	448		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q7Z5R6-467-	GQIPQA...	467		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q7Z5R6-467-	GQIPQA...	467		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q7Z5R6-467-unknown	GQIPQA...	467		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q7Z5R6-508-	APHAPK...	508		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...RGNVS	666	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)