TopFIND 4.0

Q7Z745: Maestro heat-like repeat-containing protein family member 2B {ECO:0000312|HGNC:HGNC:26857}

General Information

Protein names
- Maestro heat-like repeat-containing protein family member 2B {ECO:0000312|HGNC:HGNC:26857}
- HEAT repeat-containing protein 7B2
- Sperm PKA-interacting factor {ECO:0000250|UniProtKB:Q7M6Y6}
- SPIF {ECO:0000250|UniProtKB:Q7M6Y6}
Gene names MROH2B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q7Z745

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTLSTEESIE MFGDINLTLG MLNKEDIVNK EDIYSHLTSV IQNTDILDDA IVQRLIYYAS 
        70         80         90        100        110        120 
KDMRDNNMLR EIRMLAGEVL VSLAAHDFNS VMYEVQSNFR ILELPDEFVV LALAELATSY 
       130        140        150        160        170        180 
VSQSIPFMMM TLLTMQTMLR LAEDERMKGT FCIALEKFSK AIYKYVNHWR DFPYPRLDAN 
       190        200        210        220        230        240 
RLSDKIFMLF WYIMEKWAPL ASPMQTLSIV KAHGPTVSLL LHREDFRGYA LGQVPWLLNQ 
       250        260        270        280        290        300 
YKDKEIDFHV TQSLKQILTA AVLYDIGLPR SLRRSIFINL LQQICRAPEP PVKENEMKAS 
       310        320        330        340        350        360 
SCFLILAHSN PGELMEFFDE QVRSNNEAIR VGILTLLRLA VNADEPRLRD HIISIERTVK 
       370        380        390        400        410        420 
IVMGDLSTKV RNSVLLLIQT MCEKSYIEAR EGWPLIDYVF SQFATLNRNL EKPVKTNFHE 
       430        440        450        460        470        480 
NEKEEESVRE TSLEVLKTLD PLVIGMPQVL WPRILTFVVP AEYTEALEPL FSIIRILIMA 
       490        500        510        520        530        540 
EEKKQHSAKE STALVVSTGA VKLPSPQQLL ARLLVISMPA SLGELRGAGA IGLLKILPEI 
       550        560        570        580        590        600 
IHPKLVDLWK TRLPELLQPL EGKNISTVLW ETMLLQLLKE SLWKISDVAW TIQLTQDFKQ 
       610        620        630        640        650        660 
QMGSYSNNST EKKFLWKALG TTLACCQDSD FVNSQIKEFL TAPNQLGDQR QGITSILGYC 
       670        680        690        700        710        720 
AENHLDIVLK VLKTFQNQEK FFMNRCKSLF SGKKSLTKTD VMVIYGAVAL HAPKKQLLSR 
       730        740        750        760        770        780 
LNQDIISQVL SLHGQCSQVL GMSVMNKDMD LQMSFTRSIT EIGIAVQDAE DQGFQFSYKE 
       790        800        810        820        830        840 
MLIGYMLDFI RDEPLDSLAS PIRWKALIAI RYLSKLKPQL SLQDHLNILE ENIRRLLPLP 
       850        860        870        880        890        900 
PLENLKSEGQ TDKDKEHIQF LYERSMDALG KLLKTMMWDN VNAEDCQEMF NLLQMWLVSQ 
       910        920        930        940        950        960 
KEWERERAFQ ITAKVLTNDI EAPENFKIGS LLGLLAPHSC DTLPTIRQAA ASSTIGLFYI 
       970        980        990       1000       1010       1020 
KGIHLEVERL QGLQEGLESD DVQVQIKISS KIAKIVSKFI PNEEILMFLE EMLDGLESLN 
      1030       1040       1050       1060       1070       1080 
PTCTKACGIW MITVLKQQGA ALEDQLLEIL GTIYHHMPVL RQKEESFQFI LEAISQIASF 
      1090       1100       1110       1120       1130       1140 
HMDTVVVNLL QKPLPFDRDT KTLWKALAEK PASSGKLLQA LIDKLETELE DDIARVEAIS 
      1150       1160       1170       1180       1190       1200 
VACAMYEVIS MGTSVTGLYP ELFTLLLKLV SCTLGQKMLT CPWSHRRHVM QQGEQQQIPD 
      1210       1220       1230       1240       1250       1260 
PCRLSTATLK CLQAQAMREG LAKESDEGDN LWTLLSSPST HHIGVCSLAR SMAVWQHGVI 
      1270       1280       1290       1300       1310       1320 
LDIMEQLLSS LTSSSENYRI TGAAFFSELM KEPILWKHGN LRNVLILMDQ SAWDSNATLR 
      1330       1340       1350       1360       1370       1380 
QMAIRGLGNT ASGAPHKVKK HKQLMLESII RGLYHLARTE VVCESLKALK KILELLTDRD 
      1390       1400       1410       1420       1430       1440 
VSFYFKEIVL QTRTFFEDEQ DDVRLTAIFL FEDLAPLTGR RWKIFFAEEI KKSLISFLLH 
      1450       1460       1470       1480       1490       1500 
LWDPNPKIGV ACRDVLMVCI PFLGLQELYG VLDRLLDQDL PRARDFYRQF CVKLAKKNQE 
      1510       1520       1530       1540       1550       1560 
ILWILHTHSF TFFTSTWEVI RSAAVKLTDA VVLNLTSQYV ELLDREQLTT RLQALRQDPC 
      1570       1580    
ISVQRAAEAA LQTLLRRCKE TSIPL

Isoforms

- Isoform 2 of Maestro heat-like repeat-containing protein family member 2B

Sequence View

        10         20         30         40         50         60 
MTLSTEESIE MFGDINLTLG MLNKEDIVNK EDIYSHLTSV IQNTDILDDA IVQRLIYYAS 
        70         80         90        100        110        120 
KDMRDNNMLR EIRMLAGEVL VSLAAHDFNS VMYEVQSNFR ILELPDEFVV LALAELATSY 
       130        140        150        160        170        180 
VSQSIPFMMM TLLTMQTMLR LAEDERMKGT FCIALEKFSK AIYKYVNHWR DFPYPRLDAN 
       190        200        210        220        230        240 
RLSDKIFMLF WYIMEKWAPL ASPMQTLSIV KAHGPTVSLL LHREDFRGYA LGQVPWLLNQ 
       250        260        270        280        290        300 
YKDKEIDFHV TQSLKQILTA AVLYDIGLPR SLRRSIFINL LQQICRAPEP PVKENEMKAS 
       310        320        330        340        350        360 
SCFLILAHSN PGELMEFFDE QVRSNNEAIR VGILTLLRLA VNADEPRLRD HIISIERTVK 
       370        380        390        400        410        420 
IVMGDLSTKV RNSVLLLIQT MCEKSYIEAR EGWPLIDYVF SQFATLNRNL EKPVKTNFHE 
       430        440        450        460        470        480 
NEKEEESVRE TSLEVLKTLD PLVIGMPQVL WPRILTFVVP AEYTEALEPL FSIIRILIMA 
       490        500        510        520        530        540 
EEKKQHSAKE STALVVSTGA VKLPSPQQLL ARLLVISMPA SLGELRGAGA IGLLKILPEI 
       550        560        570        580        590        600 
IHPKLVDLWK TRLPELLQPL EGKNISTVLW ETMLLQLLKE SLWKISDVAW TIQLTQDFKQ 
       610        620        630        640        650        660 
QMGSYSNNST EKKFLWKALG TTLACCQDSD FVNSQIKEFL TAPNQLGDQR QGITSILGYC 
       670        680        690        700        710        720 
AENHLDIVLK VLKTFQNQEK FFMNRCKSLF SGKKSLTKTD VMVIYGAVAL HAPKKQLLSR 
       730        740        750        760        770        780 
LNQDIISQVL SLHGQCSQVL GMSVMNKDMD LQMSFTRSIT EIGIAVQDAE DQGFQFSYKE 
       790        800        810        820        830        840 
MLIGYMLDFI RDEPLDSLAS PIRWKALIAI RYLSKLKPQL SLQDHLNILE ENIRRLLPLP 
       850        860        870        880        890        900 
PLENLKSEGQ TDKDKEHIQF LYERSMDALG KLLKTMMWDN VNAEDCQEMF NLLQMWLVSQ 
       910        920        930        940        950        960 
KEWERERAFQ ITAKVLTNDI EAPENFKIGS LLGLLAPHSC DTLPTIRQAA ASSTIGLFYI 
       970        980        990       1000       1010       1020 
KGIHLEVERL QGLQEGLESD DVQVQIKISS KIAKIVSKFI PNEEILMFLE EMLDGLESLN 
      1030       1040       1050       1060       1070       1080 
PTCTKACGIW MITVLKQQGA ALEDQLLEIL GTIYHHMPVL RQKEESFQFI LEAISQIASF 
      1090       1100       1110       1120       1130       1140 
HMDTVVVNLL QKPLPFDRDT KTLWKALAEK PASSGKLLQA LIDKLETELE DDIARVEAIS 
      1150       1160       1170       1180       1190       1200 
VACAMYEVIS MGTSVTGLYP ELFTLLLKLV SCTLGQKMLT CPWSHRRHVM QQGEQQQIPD 
      1210       1220       1230       1240       1250       1260 
PCRLSTATLK CLQAQAMREG LAKESDEGDN LWTLLSSPST HHIGVCSLAR SMAVWQHGVI 
      1270       1280       1290       1300       1310       1320 
LDIMEQLLSS LTSSSENYRI TGAAFFSELM KEPILWKHGN LRNVLILMDQ SAWDSNATLR 
      1330       1340       1350       1360       1370       1380 
QMAIRGLGNT ASGAPHKVKK HKQLMLESII RGLYHLARTE VVCESLKALK KILELLTDRD 
      1390       1400       1410       1420       1430       1440 
VSFYFKEIVL QTRTFFEDEQ DDVRLTAIFL FEDLAPLTGR RWKIFFAEEI KKSLISFLLH 
      1450       1460       1470       1480       1490       1500 
LWDPNPKIGV ACRDVLMVCI PFLGLQELYG VLDRLLDQDL PRARDFYRQF CVKLAKKNQE 
      1510       1520       1530       1540       1550       1560 
ILWILHTHSF TFFTSTWEVI RSAAVKLTDA VVLNLTSQYV ELLDREQLTT RLQALRQDPC 
      1570       1580    
ISVQRAAEAA LQTLLRRCKE TSIPL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q7Z745-1-unknown MTLSTE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q7Z745-297-unknown MKASSC... 297 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81531

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TSIPL 1585 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...TSIPL 1585 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt77149

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)