TopFIND 4.0

Q80U87: Ubiquitin carboxyl-terminal hydrolase 8 {ECO:0000305}

General Information

Protein names
- Ubiquitin carboxyl-terminal hydrolase 8 {ECO:0000305}
- 3.4.19.12 {ECO:0000269|PubMed:16120644}
- Deubiquitinating enzyme 8
- Ubiquitin isopeptidase Y
- mUBPy
- Ubiquitin thioesterase 8
- Ubiquitin-specific-processing protease 8
Gene names Usp8
Organism Mus musculus
Protease Family
Protease ID C19.011
Chromosome location
UniProt ID Q80U87

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPAVASVPKE LYLSSSLKDL NKKTEVKPEK TSTKNYIHSA QKIFKTAEEC RLDRDEERAY 
        70         80         90        100        110        120 
VLYMKYVAVY NLIKKRPDFK QQQDYYLSIL GPANIKKAIE EAERLSESLK LRYEEAEVRK 
       130        140        150        160        170        180 
QLEEKDRREE EQLQQQKRQE MGREDSGAAA KRSVENLLDS KTKTQRINGE KSEGAAAAER 
       190        200        210        220        230        240 
GAITAKELYT MMMDKNTSLI IMDARKIQDY QHSCILDSLS VPEEAISPGV TASWIEANLS 
       250        260        270        280        290        300 
DDSKDTWKKR GSVDYVVLLD WFSSAKDLLL GTTLRSLKDA LFKWESKTVL RHEPLVLEGG 
       310        320        330        340        350        360 
YENWLLCYPQ FTTNAKVTPP PRSRAEEVSV SLDFTYPSLE EPVPSKLPTQ MPPPPIETNE 
       370        380        390        400        410        420 
KALLVTDQDE KLRLSTQPAL AGPGAAPRAE ASPIIQPAPA TKSVPQVDRT KKPSVKLPED 
       430        440        450        460        470        480 
HRIKSENTDQ SGRVLSDRST KPVFPSPTTM LTDEEKARIH QETALLMEKN KQEKELWDKQ 
       490        500        510        520        530        540 
QKEQKEKLRR EEQERKAGKT QDADERDSTE NQHKAKDGQE KKDSKQTKTE DRELSADGAQ 
       550        560        570        580        590        600 
EATGTQRQSK SEHEASDAKV PVEGKRCPTS EAQKRPADVS PASVSGELNA GKAQREPLTR 
       610        620        630        640        650        660 
ARSEEMGRIV PGLPLGWAKF LDPITGTFRY YHSPTNTVHM YPPEMAPSSA PPSTPPTHKV 
       670        680        690        700        710        720 
KPQVPAERDR EPSKLKRSYS SPDITQALQE EEKRRPAVTP MVNRENKPPC YPKAEISRLS 
       730        740        750        760        770        780 
ASQIRNLNPV FGGSGPALTG LRNLGNTCYM NSILQCLCNA PHLADYFNRN CYQDDINRSN 
       790        800        810        820        830        840 
LLGHKGEVAE EFGIIMKALW TGQYRYISPK DFKVTIGKIN DQFAGSSQQD SQELLLFLMD 
       850        860        870        880        890        900 
GLHEDLNKAD NRKRHKEENN EHLDDLQAAE HAWQKHKQLN ESIIVALFQG QFKSTVQCLT 
       910        920        930        940        950        960 
CRRRSRTFEA FMYLSLPLAS TSKCTLQDCL RLFSKEEKLT DNNRFYCSHC RARRDSLKKI 
       970        980        990       1000       1010       1020 
EIWKLPPVLL VHLKRFSYDG RWKQKLQTSV DFPLENLDLS QYVIGPKNSL KKYNLFSVSN 
      1030       1040       1050       1060       1070       1080 
HYGGLDGGHY TAYCKNAARQ RWFKFDDHEV SDISVSSVRS SAAYILFYTS LGPRITDVAT 
   

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q80U87-1-unknown MPAVAS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q80U87-364-unknown LVTDQD... 364 inferred from cleavage unknown TopFIND Inferred from cleavage TC30691

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)