TopFIND 4.0

Q80UF9: Proton channel OTOP3 {ECO:0000305}

General Information

Protein names
- Proton channel OTOP3 {ECO:0000305}
- Otopetrin-3 {ECO:0000303|PubMed:12651873}
Gene names Otop3
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q80UF9

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASQTSAPAE PAPMPSPEAK TTEGASSYDQ ADMETKHAGS PCPPKQKSWL ARHFSLLLRR 
        70         80         90        100        110        120 
DRQAQKAGQL FSGLLALNVV FLGGAFICSM IFNKVSVTLG DVWILLAALK VLSLLWLLYY 
       130        140        150        160        170        180 
TVGTTRKPHA VLYRDPHAGP IWVRGSLVLF GSCTVCLNIF RMGYDVSHIH CKSEVELIFP 
       190        200        210        220        230        240 
AIEIVFMIIQ TWVLWRHCKD CVQVQTNFTR CGLMLTLATN LLMWVLAVTN DSMHREIEAE 
       250        260        270        280        290        300 
LDALMEKFSG NGTNTCMCLN TTVCEVFRKG YLMLYPFSTE YCLICCAVLF VMWKNVSRSL 
       310        320        330        340        350        360 
AAHTGAHPNR SPFRLHGTIF GPLLGLLALV AGVCVFVLFQ IEASGPDIAR QYFTLYYAFY 
       370        380        390        400        410        420 
VAVLPTMSLA CLAGTAIHGL EERELDTLKN PTRSLDVVLL MGAALGQMGI AYFSIVAIVA 
       430        440        450        460        470        480 
TQPHELLNQL ILAYSLLLIL QHITQNLFII EGLHRRPLWE PAVSGVMEKQ DVELPRRGSL 
       490        500        510        520        530        540 
RELGQDLRRA SRAYIHSFSH LNWKRRMLKE ISLFLILCNI TLWMMPAFGI HPEFENGLEK 
       550        560        570    
DFYGYRTWFT IVNFGLPLGV FYRMHSVGGL VEVYLGA

Isoforms

- Isoform 2 of Otopetrin-3 - Isoform 2 of Proton channel OTOP3

Sequence View

        10         20         30         40         50         60 
MASQTSAPAE PAPMPSPEAK TTEGASSYDQ ADMETKHAGS PCPPKQKSWL ARHFSLLLRR 
        70         80         90        100        110        120 
DRQAQKAGQL FSGLLALNVV FLGGAFICSM IFNKVSVTLG DVWILLAALK VLSLLWLLYY 
       130        140        150        160        170        180 
TVGTTRKPHA VLYRDPHAGP IWVRGSLVLF GSCTVCLNIF RMGYDVSHIH CKSEVELIFP 
       190        200        210        220        230        240 
AIEIVFMIIQ TWVLWRHCKD CVQVQTNFTR CGLMLTLATN LLMWVLAVTN DSMHREIEAE 
       250        260        270        280        290        300 
LDALMEKFSG NGTNTCMCLN TTVCEVFRKG YLMLYPFSTE YCLICCAVLF VMWKNVSRSL 
       310        320        330        340        350        360 
AAHTGAHPNR SPFRLHGTIF GPLLGLLALV AGVCVFVLFQ IEASGPDIAR QYFTLYYAFY 
       370        380        390        400        410        420 
VAVLPTMSLA CLAGTAIHGL EERELDTLKN PTRSLDVVLL MGAALGQMGI AYFSIVAIVA 
       430        440        450        460        470        480 
TQPHELLNQL ILAYSLLLIL QHITQNLFII EGLHRRPLWE PAVSGVMEKQ DVELPRRGSL 
       490        500        510        520        530        540 
RELGQDLRRA SRAYIHSFSH LNWKRRMLKE ISLFLILCNI TLWMMPAFGI HPEFENGLEK 
       550        560        570    
DFYGYRTWFT IVNFGLPLGV FYRMHSVGGL VEVYLGA         10         20         30         40         50         60 
MASQTSAPAE PAPMPSPEAK TTEGASSYDQ ADMETKHAGS PCPPKQKSWL ARHFSLLLRR 
        70         80         90        100        110        120 
DRQAQKAGQL FSGLLALNVV FLGGAFICSM IFNKVSVTLG DVWILLAALK VLSLLWLLYY 
       130        140        150        160        170        180 
TVGTTRKPHA VLYRDPHAGP IWVRGSLVLF GSCTVCLNIF RMGYDVSHIH CKSEVELIFP 
       190        200        210        220        230        240 
AIEIVFMIIQ TWVLWRHCKD CVQVQTNFTR CGLMLTLATN LLMWVLAVTN DSMHREIEAE 
       250        260        270        280        290        300 
LDALMEKFSG NGTNTCMCLN TTVCEVFRKG YLMLYPFSTE YCLICCAVLF VMWKNVSRSL 
       310        320        330        340        350        360 
AAHTGAHPNR SPFRLHGTIF GPLLGLLALV AGVCVFVLFQ IEASGPDIAR QYFTLYYAFY 
       370        380        390        400        410        420 
VAVLPTMSLA CLAGTAIHGL EERELDTLKN PTRSLDVVLL MGAALGQMGI AYFSIVAIVA 
       430        440        450        460        470        480 
TQPHELLNQL ILAYSLLLIL QHITQNLFII EGLHRRPLWE PAVSGVMEKQ DVELPRRGSL 
       490        500        510        520        530        540 
RELGQDLRRA SRAYIHSFSH LNWKRRMLKE ISLFLILCNI TLWMMPAFGI HPEFENGLEK 
       550        560        570    
DFYGYRTWFT IVNFGLPLGV FYRMHSVGGL VEVYLGA



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q80UF9-1-unknown MASQTS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q80UF9-1-unknown MASQTS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt83913

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VYLGA 577 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VYLGA 577 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79531

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)