Q80W14: Pre-mRNA-processing factor 40 homolog B

General Information

Protein names	- Pre-mRNA-processing factor 40 homolog B - Huntingtin yeast partner C - Huntingtin-interacting protein C
Gene names	Prpf40b
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q80W14

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Pre-mRNA-processing factor 40 homolog B - Isoform 3 of Pre-mRNA-processing factor 40 homolog B

Sequence View

        10         20         30         40         50         60
MMPPPFMPPP GLPPPFPPMG LPPMSQRPPA IPPMPPGILP PMLPPMGAPP PLTQIPGMVP
        70         80         90        100        110        120
PMMPGMLMPA VPVTAATAPG ADTASSAVAG TGPPRALWSE HVAPDGRIYY YNADDKQSVW
       130        140        150        160        170        180
EKPSVLKSKA ELLLSQCPWK EYKSDTGKPY YYNNQSQESR WTRPKDLDDL EALVKQESAG
       190        200        210        220        230        240
KQQTQQLQTL QPQPPQPQPD PPPIPPGPIP VPMALLEPEP GRSEDCDVLE AAQPLEQGFL
       250        260        270        280        290        300
QREEGPSSST GQHRQPQEEE EAKPEPERSG LSWSNREKAK QAFKELLRDK AVPSNASWEQ
       310        320        330        340        350        360
AMKMVVTDPR YSALPKLSEK KQAFNAYKAQ REKEEKEEAR LRAKEAKQTL QHFLEQHERM
       370        380        390        400        410        420
TSTTRYRRAE QTFGDLEVWA VVPERERKEV YDDVLFFLAK KEKEQAKQLR RRNIQALKSI
       430        440        450        460        470        480
LDGMSSVNFQ TTWSQAQQYL MDNPSFAQDQ QLQNMDKEDA LICFEEHIRA LEREEEEERE
       490        500        510        520        530        540
RARLRERRQQ RKNREAFQSF LDELHETGQL HSMSTWMELY PAVSTDVRFA NMLGQPGSTP
       550        560        570        580        590        600
LDLFKFYVEE LKARFHDEKK IIKDILKDRG FCVEVNTAFE DFAHVISFDK RAAALDAGNI
       610        620        630        640        650        660
KLTFNSLLEK AEARETEREK EEARRMRRRE AAFRSMLRQA VPALELGTAW EEVRERFVCD
       670        680        690        700        710        720
SAFEQITLES ERIRLFREFL QVLEQTECQH LHTKGRKHGR KGKKHHRKRS HSPSGSESDE
       730        740        750        760        770        780
EELPPPSLRP PKRRRRNPSE SGSEPSSSLD SVESGGAALG GPGSPSSHLL LGSDHGLRKT
       790        800        810        820        830        840
KKPKKKTKKR RHKSTSPDSE TDPEDKAGKE SEDREQEQDR EPRQAELPNR SPGFGIKKEK
       850        860        870
TGWDTSESEL SEGELERRRR TLLQQLDDHQ         10         20         30         40         50         60
MMPPPFMPPP GLPPPFPPMG LPPMSQRPPA IPPMPPGILP PMLPPMGAPP PLTQIPGMVP
        70         80         90        100        110        120
PMMPGMLMPA VPVTAATAPG ADTASSAVAG TGPPRALWSE HVAPDGRIYY YNADDKQSVW
       130        140        150        160        170        180
EKPSVLKSKA ELLLSQCPWK EYKSDTGKPY YYNNQSQESR WTRPKDLDDL EALVKQESAG
       190        200        210        220        230        240
KQQTQQLQTL QPQPPQPQPD PPPIPPGPIP VPMALLEPEP GRSEDCDVLE AAQPLEQGFL
       250        260        270        280        290        300
QREEGPSSST GQHRQPQEEE EAKPEPERSG LSWSNREKAK QAFKELLRDK AVPSNASWEQ
       310        320        330        340        350        360
AMKMVVTDPR YSALPKLSEK KQAFNAYKAQ REKEEKEEAR LRAKEAKQTL QHFLEQHERM
       370        380        390        400        410        420
TSTTRYRRAE QTFGDLEVWA VVPERERKEV YDDVLFFLAK KEKEQAKQLR RRNIQALKSI
       430        440        450        460        470        480
LDGMSSVNFQ TTWSQAQQYL MDNPSFAQDQ QLQNMDKEDA LICFEEHIRA LEREEEEERE
       490        500        510        520        530        540
RARLRERRQQ RKNREAFQSF LDELHETGQL HSMSTWMELY PAVSTDVRFA NMLGQPGSTP
       550        560        570        580        590        600
LDLFKFYVEE LKARFHDEKK IIKDILKDRG FCVEVNTAFE DFAHVISFDK RAAALDAGNI
       610        620        630        640        650        660
KLTFNSLLEK AEARETEREK EEARRMRRRE AAFRSMLRQA VPALELGTAW EEVRERFVCD
       670        680        690        700        710        720
SAFEQITLES ERIRLFREFL QVLEQTECQH LHTKGRKHGR KGKKHHRKRS HSPSGSESDE
       730        740        750        760        770        780
EELPPPSLRP PKRRRRNPSE SGSEPSSSLD SVESGGAALG GPGSPSSHLL LGSDHGLRKT
       790        800        810        820        830        840
KKPKKKTKKR RHKSTSPDSE TDPEDKAGKE SEDREQEQDR EPRQAELPNR SPGFGIKKEK
       850        860        870
TGWDTSESEL SEGELERRRR TLLQQLDDHQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q80W14-1-unknown	MMPPPF...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q80W14-1-unknown	MMPPPF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86076
Q80W14-1-unknown	MMPPPF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86077
Q80W14-7-unknown	MPPPGL...	7	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122649
Q80W14-7-unknown	MPPPGL...	7	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133072
Q80W14-7-unknown	MPPPGL...	7	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133073
Q80W14-628-unknown	RREAAF...	628	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119295
Q80W14-628-unknown	RREAAF...	628	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133075

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LLLSQC	136	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119556
...LLLSQC	136	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115624
...LLLSQC	136	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115625
...ELSEGE	853	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000023745
...ELSEGE	853	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115627
...LDDHQ	870	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LDDHQ	870	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81695

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)