TopFIND 4.0

Q80XL1: E3 ubiquitin-protein ligase CBL-C

General Information

Protein names
- E3 ubiquitin-protein ligase CBL-C
- 2.3.2.27 {ECO:0000250|UniProtKB:Q9ULV8}
- RING-type E3 ubiquitin transferase CBL-C {ECO:0000305}
- SH3-binding protein CBL-3
- SH3-binding protein CBL-C
- Signal transduction protein CBL-C
Gene names Cblc
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q80XL1

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAAAAPRGW QRGEPRALSR AVKLLQRLEE QCRDPRMVTG PPSLRDLLPR TAQLLGEVAK 
        70         80         90        100        110        120 
ARREAREDPE GPGGADDFLA IYLANLEVKG RQVAELLPPR GKKDVNQDVF REGSRFRRQL 
       130        140        150        160        170        180 
AKLALIFSHM HAELSALFPA GKYCGHLYQL TKGSAHIFWR QNCGVRCVLP WAEFQSLLCA 
       190        200        210        220        230        240 
CHPVEPGPTM QALRSTLDLT CNGHVSVFEF DVFTRLFQPW PTLLRNWQLL AVNHPGYMAF 
       250        260        270        280        290        300 
LTYDEVQTRL QAYRDKPGSY IFRPSCTRLG QWAIGYVSSD GSILQTIPLN KPLLQVLLKG 
       310        320        330        340        350        360 
QKDGIFLFPD GKKHNPDLTE LCRVEPYQRI QVSEEQLLLY QAMNSTFQLC KICAERDKDV 
       370        380        390        400        410        420 
RIEPCGHLLC SCCLAAWQDS DSQTCPFCRC EIKGREAVSI CQAQERPTEV RTAADGSRDN 
       430        440        450        460        470        480 
CHQEAAEQKL GPVIPSAPSL LPEDQFPQGP QDKGWLTLAP LALPRLRPPL PLPKMASVLW 
       490    
EVTSRPRARE EATESS

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase CBL-C

Sequence View

        10         20         30         40         50         60 
MAAAAAPRGW QRGEPRALSR AVKLLQRLEE QCRDPRMVTG PPSLRDLLPR TAQLLGEVAK 
        70         80         90        100        110        120 
ARREAREDPE GPGGADDFLA IYLANLEVKG RQVAELLPPR GKKDVNQDVF REGSRFRRQL 
       130        140        150        160        170        180 
AKLALIFSHM HAELSALFPA GKYCGHLYQL TKGSAHIFWR QNCGVRCVLP WAEFQSLLCA 
       190        200        210        220        230        240 
CHPVEPGPTM QALRSTLDLT CNGHVSVFEF DVFTRLFQPW PTLLRNWQLL AVNHPGYMAF 
       250        260        270        280        290        300 
LTYDEVQTRL QAYRDKPGSY IFRPSCTRLG QWAIGYVSSD GSILQTIPLN KPLLQVLLKG 
       310        320        330        340        350        360 
QKDGIFLFPD GKKHNPDLTE LCRVEPYQRI QVSEEQLLLY QAMNSTFQLC KICAERDKDV 
       370        380        390        400        410        420 
RIEPCGHLLC SCCLAAWQDS DSQTCPFCRC EIKGREAVSI CQAQERPTEV RTAADGSRDN 
       430        440        450        460        470        480 
CHQEAAEQKL GPVIPSAPSL LPEDQFPQGP QDKGWLTLAP LALPRLRPPL PLPKMASVLW 
       490    
EVTSRPRARE EATESS



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q80XL1-1-unknown MAAAAA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q80XL1-1-unknown MAAAAA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt69425

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ATESS 496 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)