Q86SG6: Serine/threonine-protein kinase Nek8

General Information

Protein names	- Serine/threonine-protein kinase Nek8 - 2.7.11.1 - Never in mitosis A-related kinase 8 - NimA-related protein kinase 8 - Nima-related protein kinase 12a
Gene names	NEK8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86SG6

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEKYERIRVV GRGAFGIVHL CLRKADQKLV IIKQIPVEQM TKEERQAAQN ECQVLKLLNH
        70         80         90        100        110        120
PNVIEYYENF LEDKALMIAM EYAPGGTLAE FIQKRCNSLL EEETILHFFV QILLALHHVH
       130        140        150        160        170        180
THLILHRDLK TQNILLDKHR MVVKIGDFGI SKILSSKSKA YTVVGTPCYI SPELCEGKPY
       190        200        210        220        230        240
NQKSDIWALG CVLYELASLK RAFEAANLPA LVLKIMSGTF APISDRYSPE LRQLVLSLLS
       250        260        270        280        290        300
LEPAQRPPLS HIMAQPLCIR ALLNLHTDVG SVRMRRAEKS VAPSNTGSRT TSVRCRGIPR
       310        320        330        340        350        360
GPVRPAIPPP LSSVYAWGGG LGTPLRLPML NTEVVQVAAG RTQKAGVTRS GRLILWEAPP
       370        380        390        400        410        420
LGAGGGSLLP GAVEQPQPQF ISRFLEGQSG VTIKHVACGD FFTACLTDRG IIMTFGSGSN
       430        440        450        460        470        480
GCLGHGSLTD ISQPTIVEAL LGYEMVQVAC GASHVLALST ERELFAWGRG DSGRLGLGTR
       490        500        510        520        530        540
ESHSCPQQVP MPPGQEAQRV VCGIDSSMIL TVPGQALACG SNRFNKLGLD HLSLGEEPVP
       550        560        570        580        590        600
HQQVEEALSF TLLGSAPLDQ EPLLSIDLGT AHSAAVTASG DCYTFGSNQH GQLGTNTRRG
       610        620        630        640        650        660
SRAPCKVQGL EGIKMAMVAC GDAFTVAIGA ESEVYSWGKG ARGRLGRRDE DAGLPRPVQL
       670        680        690
DETHPYTVTS VSCCHGNTLL AVRSVTDEPV PP

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q86SG6-1-unknown	MEKYER...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q86SG6-40-unknown	MTKEER...	40	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467335
Q86SG6-40-unknown	MTKEER...	40	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466896

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KRAFEA	204	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467335
...AFEAAN	206	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466896
...TACLTD	407	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466476
...EPVPP	692	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)